• Journal of Korean Neurosurgical Society
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• 제48권2호
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• pp.177-180
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• 2010

Giant serpentine aneurysms are rare and have distinct angiographic findings. The rarity, large size, complex anatomy and hemodynamic characteristics of giant serpentine aneurysms make treatment difficult. We report a case of a giant serpentine aneurysm of the right middle cerebral artery (MCA) that presented as headache. Treatment involved a superficial temporal artery (STA)-MCA bypass followed by aneurysm resection. The patient was discharged without neurological deficits, and early and late follow-up angiography disclosed successful removal of the aneurysm and a patent bypass graft. We conclude that STA-MCA bypass and aneurysm excision is a successful treatment method for a giant serpentine aneurysm.

• 대한상부위장관⦁헬리코박터학회지
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• 제18권3호
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• pp.150-156
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• 2018

Precision medicine stands for 4Ps - precise, preventive, participatory, and personal; in which "precision" is important because the current modern medicine starts from "trial and error," and "one does not fit all". Current targeted therapies for cancer have changed treatment approaches and led the precision medicine; however, clinical use of liquid biopsy, using blood or other liquid specimens to characterize circulating tumor cells (CTC) or tumor genes instead of biopsies of tumor tissues, still awaits availability of more information regarding non-invasive cancer detection and characterization, prediction of treatment response, monitoring the disease course and relapse possibilities, identification of mechanisms of drug resistance, and newer pathogenesis. In this review, we will introduce the basic concept of CTC, circulating cell free DNA, and exosomes and their possible application for gastric cancer relevant with Helicobacter pylori infection.

• 한국산업융합학회 논문집
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• 제25권6_2호
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• pp.1083-1090
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• 2022

Since renal cell carcinoma(RCC) has various examination and treatment methods according to clinical stage and histopathological characteristics, it is required to determine accurate and efficient treatment methods in the clinical field. However, the process of collecting and processing RCC medical data is difficult and complex, so there is currently no AI-based clinical decision support system for RCC treatments worldwide. In this study, we propose a clinical decision support system that helps clinicians decide on a precision treatment to each patient. RCC standard big database is built by collecting structured and unstructured data from the standard common data model and electronic medical information system. Based on this, various machine learning classification algorithms are applied to support a better clinical decision making.

• 동의생리병리학회지
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• 제35권5호
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• pp.193-198
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• 2021

The purpose of this study is to observe the effect of Cordyceps Militaris(CM) complex extract treatment on patients diagnosed with rheumatoid arthritis(RA). We reviewed medical records of 9 rheumatoid arthritis patients who visited the pain & rehabilitation center, Daejeon Korean Medicine Hospital of Daejeon University and were treated with CM complex extract from October 14, 2019 to October 14, 2020. We analyzed the records of DAS 28(Disease Activity Score 28), CDAI(Clinical Disease Activity Index), SDAI(Simplified Disease Activity Index), VAS(Visual analogue Scale), and KHAQ-D(Korean Health Assesment Questionnaire-Disability Index) before and after treatment to evaluate the effects of CM complex extract on RA. As a result, the scores of DAS 28(p<0.05), CDAI(p<0.01), SDAI(p<0.01) and VAS(p<0.01) were statistically significantly decreased, after 8 weeks of taking CM complex extract in RA patients. In conclusion, CM complex extract treatment may have potential effects of reducing disease activity and pain and improving quality of life in patients diagnosed with RA.

• 동의생리병리학회지
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• 제33권4호
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• pp.219-225
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• 2019

The objective of this study is to observe the effectiveness of complex Korean Medicine treatments on pain reduction of patients after meniscal surgery. We analyzed 16 patients who have been diagnosed as Meniscal injury on Magnetic Resonance Imaging(MRI) scan and had admitted to Dunsan Korean Medical hospital from January 30, 2014 to April 30, 2019. The analysis was conducted as retrospective study which analyzes patient's medical records. Statistical analysis was performed using the IBM SPSS statistics 25 program. We used Numeric Rating Scale to evaluate pain reduction, Five-point likert scale to asses treatment satisfaction. The result showed that there were statistically significant pain reduction on the postoperative meniscal injury patients treated with complex Korean Medicine treatments. In conclusion, we found that the complex Korean Medicine treatments showed a positive effect on pain reduction of postoperative meniscal injury patients. Further research is required to confirm the effectiveness of Korean Medicine treatment.

• 대한치과의사협회지
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• 제48권1호
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• pp.27-37
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• 2010

Current trend of aging society suggests that many patients are at risk for various preoperative preparations and postoperative complications during and following invasive dental procedures, due to an acquired medically compromised conditions from systemic disease and/or from medications. The medical history is critical for the identification of patients potentially at risk for medically compromised and old aged patients' factors from dental treatment. The proper dental management requires an understanding of certain principles of pathophysiology for these medical conditions and some standard laboratory tests. Polypharmacy in old age, besides representing a risk in and of itself, points to the potential risk the underlying diseases that necessitated the drugs can present in the dental office. These diseases and medications can also present a risk to oral health. A sequence for categorizing drugs in a medication list is presented here to aid in the identification of potential risks in the dental treatment and management of patients with complex medical histories and drug regimens. Specific patient populations, such as pediatric, may have specific drugs or additional criteria that need to be considered. Practitioners must use the health history and the medication list in concert, using one to make sense of the other and utilizing all the information available from reviewing each one carefully in order to manage their increasingly complex patients safely and effectively.

• 대한한방내과학회지
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• 제26권2호
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• pp.489-497
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• 2005

Conversion disorder lacks temperamental grounds and is a type of somatoform disorder that includes alteration or loss of physical functions implicated in physical deficit suggestive psychological conflict. There is high incidence of return of conversion disorder and difficulty in producing exact approaches of cure and apparent effects of remedy with symptomatic treatment alone because of its complex clinical symptoms. The approach of Oriental Medicine in treatment of conversion disorder is to apprehend relative symptoms from the syndrome combined with several annexational symptoms centering around sequential symptoms. Thereupon, author made a Ganyanghwapung comprehensive diagnosis was conducted using Oriental Medicine measures by differential diagnostic methods in psychosomatic patients whose cases are diagnosed as conversion disorder. Then, Cheonmagudeungeum Gagambang was prescribed for them and it brought on satisfactory effects from the first or second treatment. There have been many cases reporting the application of Oriental Medicine treatment to conversion disorder to date and outcomes have also been favorable. Results of this study likewise suggest that this Oriental Medicine treatment for conversion disorder is effective.

• 의료법학
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• 제5권1호
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• pp.622-660
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• 2004

Medical services aren't done by doctors only but by different medical personnels. If any medical accident takes place, to what extent doctors, nurses and other personnels should respectively be liable for that should be determined. And when an employed doctor does any illegal medical act, his or her employer also should be responsible for that as a user. If a medical accident occurs, the victim or patient usually claims against the employer of the doctor sho causes the accident for compensation. And those who assist medical treatment, including nurses, should be liable for their own acts, but in case their doctor doesn't give any appropriate directions, the doctor should shoulder the liability. This indicates that nurses are also professional medical personnels, and that they should share the liability as well. There are lots of different medical personnels, but doctors and nurses are the pivot of team treatment, and nurses should also take responsibility for their services. Doctors and nurses are equal, as they are in pursuit of the same, namely, helping patients recover their health. Only their roles are different. If they respect each other and see each other as being responsible for their own roles, they will be able to consult together. Medical information on patients and nursing information should be shared by both of them, and patients should be provided accurate treatment and nursing services. If those who offer nursing services are unaware of required information due to conflicts with doctors, it might result in threatening the safety of patients. And in case any important information isn't properly conveyed between them, it might trigger a medical accident. Sophisticated and complex medical science requires medical personnels to be professional, and nurses as well as doctors need to be an expert. The fact treatment-related accidents take place often indicates that treatment is basically attended with danger. Furthermore, patients respond to all sorts of investigation and medicine in a different manner. They should be professional and knowledgeable to predict how they might respond and prevent any possible hazardous situations, and they are expected to have more knowledge in the future. Nonetheless, there aren't yet enough studies on the legal liability of nurses, and this study is expected to pave the way for future research on nurse liability against medical accidents.

• Tuberculosis and Respiratory Diseases
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• 제57권3호
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• pp.234-241
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• 2004

연구배경 : MAC는 NTM 폐질환의 가장 흔한 원인균이다. Clarithromycin과 같은 새로운 항생제의 사용에도 불구하고, 아직까지 MAC 폐질환의 내과적 치료성적은 만족스럽지 못한 실정이다. 본 연구는 MAC 폐질환 환자를 대상으로 clarithromycin이 포함된 내과적 치료의 효과를 알아보고자 하였다. 대상 및 방법 : 2000년 1월부터 2003년 12월까지 삼성서울병원 호흡기내과에서 진단된 MAC 폐질환 환자 56명 중 clarithromycin이 포함된 병합 항생제 치료를 6개월 이상 시행한 환자 15명을 대상으로 하여 후향적 조사를 시행하였다. 결 과 : 남자가 6명(40%) 여자가 9명(60%)이었고, 연령의 중앙값은 67세(범위 53-87세)였다. 원인균은 M. intracellulare가 12명(80%), M. avium이 3명(20%)이었고, 객담 도말 양성환자가 13명(87%)이었다. 5명(27%)의 환자는 upper lobe cavitary form, 그리고 10명(67%)은 nodular bronchiectatic form이었다. 모든 환자에서 clarithromycin, rifampin, ethambutol을 투여하였고, 8명(53%)의 환자는 streptomycin을 함께 사용하였다. 치료기간은 중앙값 17개월(범위 8-22개월)이었다. 6개월 이상 치료한 15명 중 8명(53%)에서 균음전에 성공하였다. 6개월 치료 후 단순흉부방사선 촬영에서 10명(67%)이 호전되었고 5명(33%)은 변화가 없었다. 균음전에 실패한 1명은 폐절제술을 시행하였다. 폐절제술을 시행한 환자를 제외하고 12개월 이상 내과적 치료를 시행한 9명 중 4명(44%)이 균음전에 성공하였다. 12개월 치료 후 단순흉부방사선촬영에서 6명(67%)이 호전을 보였다. 전체적으로 내과적 치료 후 균음전에 성공한 환자는 9명(60%)으로, 이 중 5명의 환자는 치료 시작 1-2개월 후부터 배양 음성이 유지되었다. 1명의 환자에서 위장관 장애와 시신경염으로 치료를 중단하였다. 결 론 : MAC 폐질환에서 clarithromycin을 포함한 내과적 치료 후 균음전에 성공한 환자는 60%에 불과하였다. 보다 효과적인 치료약제의 개발이 필요하며, 내과적 치료에 반응하지 않는 환자에서는 폐절제술을 고려하여야 할 것으로 사료된다.

• 동의생리병리학회지
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• 제30권5호
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• pp.360-365
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• 2016

The purpose of this study is to suggest a possibility of the Korean medical treatment in patient with peroneal nerve palsy, and to suggest importance of differential diagnosis of foot drop. Peroneal nerve pasly was diagnosed by lumbar spine magnetic resonance imaging(MRI) and electromyogram(EMG). The patient was treated with acupuncture, herbal medicine, bee-venom acupuncture and moxibustion from March 7th to May 2nd. We measured Numerical Rating Scale(NRS), Range of Motion(ROM) of the ankle, and observed the change in body temperature using Digital Infrared Thermal Imaging(DITI). After received Korean medical treatment, the patient showed improvement in all the scales mentioned above. The result showed that Korean medical treatment is effective in peroneal nerve palsy before operation.