• Journal of the Computational Structural Engineering Institute of Korea
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• v.31 no.3
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• pp.155-163
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• 2018

One of the major disadvantages of isogeometric analysis(IGA) is that local refinement is nearly impossible in a conventional manner because of the tensor product nature in NURBS. In this research, we investigate a local refinement scheme for isogeometric analysis, named multi-resolution approach where different resolutions are employed at each subdomain, using h-refinement relation to endow displacement compatibility on an interface of subdomains. Then, we develop shape sensitivity analysis possessing same compatibility condition as in the analysis. Numerical examples are shown to demonstrate the computational efficiency of the method in analysis especially stress concentration problem and accurate sensitivity results which is also compatible on the interface.

• Korean Journal of Veterinary Research
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• v.24 no.1
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• pp.91-98
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• 1984

A total of 466 foremilk from dairy farms in Chonnam district was examined for the subclinical mastitis over a period of one year, using a method of the electrical conductivities(EC); absolute conductivity(AC) and differential conductivity(DC) and quarter difference value(QD), in relation to the California mastitis test(CMT) and the direct somatic cell count(DSCC). The compatibility and efficiency rating between the EC values and the other screening tests was conducted. Obtained results are summarized as follows. 1. A linear relationship was found between the EC values and the CMT scores and direct somatic cell counts and it was found that electrical conductivity measurements were comparable with other screening tests for diagnosing animals with mastitis. 2. Compatibilities between the EC and CMT were 70.4% in AC, 74.6% in DC and 70.7% in QD, and that of the EC and DSCC were 53.0% in AC, 63.1% in DC and 53.2% in QD. On the other hand, relative efficiency ratings of Postle's equation between EC and CMT were 37.3% in AC, 26.5% in DC and 13.6% in QD, and that of the EC and DSCC were 33.1% in AC, 20.2% in DC and 11.9% in QD. 3. In the foremilk samples collected from damaged quarters determined by EC, the false positive rate wart higher than the false negative rate, and consequently tests of EC produced lower compatibility or efficiency rating scores. These tendencies suggested that any factors other than the mastitic condition influencing the EC values might be existed.

• Journal of Pharmaceutical Investigation
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• v.40 no.6
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• pp.367-372
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• 2010

Rabeprazole sodium (RPN) is known to be very unstable at acidic condition or some acidic pharmaceutical excipients such as acrylic acid polymer (carbomer 934) with carboxylic acids. Thus, degradation mechanism of binary blends of rabeprazole with pharmaceutical excipients in a solid state without using solvents at three different ratios (3:1, 1:1 and 1:3) was investigated using Fourier transform infrad (FTIR) spectroscopy. Alkalizer (MgO), neutral hydroxypropymethylcellulose (HPMC 4000) were also tested for comparison. The binary blends were stored under accelerated conditions ($40^{\circ}C$/75% relative humidity) for two weeks. The concentration of thioether rabeprazole from the binary blends with acidic carbomer 934 increased as the rabeprazole concentration decreased. In addition, the degradation half-life of rabeprazole as well as the relative peak area ratios obtained from FTIR spectra of S=O stretching at $1094.1\;cm^{-1}$ decreased consistently as the fraction of carbomer 934 increased due to its sensitivity between the basic benzimidazole nitrogen and carboxylic acid group of carbomer 934. The physical appearance also turned into strong brown color in the presence of carbomer 934. In contrast, there were no significant changes in the degradation kinetics of rabeprazole with MgO and HPMC 4000 in a solid state. This present study demonstrated that the solid-state compatibility test with the aid of HPLC chromatographic and FTIR spectral analyses could offer a valuable methodology to select suitable pharmaceutical excipients and to elucidate the degradation mechanism of RPN for drug formulations at the early formulation stages.

• Smart Structures and Systems
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• v.33 no.1
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• pp.1-16
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• 2024

The investigation on vehicle-bridge coupling system (VBCS) is crucial in bridge design, bridge condition evaluation, and vehicle overload control. A real-time hybrid testing (RTHT) method for VBCS (RTHT-VBCS) is proposed in this paper for accurately and economically disclosing the dynamic performance of VBCSs. In the proposed method, one of the carriages is chosen as the experimental substructure loaded by servo-hydraulic actuator loading system in the laboratory, and the remaining carriages as well as the bridge structure are chosen as the numerical substructure numerically simulated in one computer. The numerical substructure and the experimental substructure are synchronized at their coupling points in terms of force equilibrium and deformation compatibility. Compared to the traditional iteration experimental method and the numerical simulation method, the proposed RTHT-VBCS method could not only obtain the dynamic response of VBCS, but also economically analyze various working conditions. Firstly, the theory of RTHT-VBCS is proposed. Secondly, numerical models of VBCS for RTHT method are presented. Finally, the feasibility and accuracy of the RTHT-VBCS are preliminarily validated by real-time hybrid simulations (RTHSs). It is shown that, the proposed RTHT-VBCS is feasible and shows great advantages over the traditional methods, and the proposed models can effectively represent the VBCS for RTHT method in terms of the force equilibrium and deformation compatibility at the coupling point. It is shown that the results of the single-degree-of-freedom model and the train vehicle model are match well with the referenced results. The RTHS results preliminarily prove the effectiveness and accuracy of the proposed RTHT-VBCS.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2000.04b
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• pp.141-149
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• 2000

This study performs the elastic and viscoelastic analysis of composite continuous beams with flexible shear connectors. Due to creep and shrinkage of the concrete part, the stress redistribution between the concrete slab and steel beam, and the evolution of the redundant restraint reaction occur with time. Using the equation of equilibrium, internal and external compatibility condition, and constitutive relationships, mathematical formulations are formulated. The solution is obtained by means of numerical step-by-step techniques and the finite difference method. Numerical parametric studies are performed to evaluate the stress redistribution, and the evolution of the redundant restraint reaction. The parameters include the stiffness and spacing of shear connectors, the age of concrete at loading, and the relative humidity.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2005.04a
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• pp.167-174
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• 2005

Through time-dependent analyses of RC bridges constructed by a movable scaffolding system (MSS) considering the construction sequence and creep deformation of concrete, structural responses related to the member forces are reviewed. On the basis of the compatibility condition and equilibrium equation at every construction stage, basic equations that can describe the moment variation with time in movable scaffolding construction are derived. By using the introduced relations, the design moment and its variation over time can easily be obtained with only the elastic analysis results and without additional time-dependent analyses considering the construction sequences. In addition, the design moments determined by the introduced equations are compared with the results from a rigorous numerical analysis with the objective of establishing the relative efficiencies of the introduced equations.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2005.04a
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• pp.481-488
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• 2005

This study presents a elastic parabolic cable element for initial shaping analysis of cable structures. First, the compatibility condition and the tangent stiffness matrices of the elastic catenary cable element are shortly summarized. Next the force-deformation relations and the tangent stiffness matrices of the elastic parabolic cable elements are derived from the assumption that sag configuration under self-weights is small. To confirm the accuracy of this element, initial shaping analysis of cable-stayed bridges under dead loads is executed. Finally, the accuracy and the validity of the analysis-results are compared and analyzed through numerical examples.

• Proceedings of the Materials Research Society of Korea Conference
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• 2009.11a
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• pp.40.2-40.2
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• 2009

Using the favorable resorption behavior of amorphous Calcium phosphate (CaP) we fabricated a gelatin basednano fibrous mat by electrospinning for using as a fast healing patch for minorbone defects. Bone is predominantly formed by an inorganic phase of nano-crystalline HAp materials and nano fibrous protein material of collagen. The osteoblast cells, which are the bone formation cells and are key to the new bone formation, receive these materials to form new bone. Taking these considerations we make a new nano fibrous mat of amorphous CaP and gelatin, which is derived from collagen itself. A polymer carrier of poly caprolactone(PCL) was used in the system to stabilize the materials in biological condition. The electrospinning conditions were optimized for smooth mat without any droplet formation. The fabricated mat was characterized for its morphologyby SEM. Mechanical properties like tensile strength was evaluated. To investigate the bio-compatibility we performed the MTT assay and investigated its resorption behavior and apatite formation behavior by SBF immersion.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.19 no.1
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• pp.128-133
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• 2010

The Titanium has many superior characteristics which are specific strength, heat resistance, corrosion resistance, organism compatibility, non-magnetic and etc. and their quantity are abundant. this study performed turning operation of Ti-6Al-4V alloy using the TiAlN Coated Tool which treated Physical Vapor Deposition. Experimental works are also executed to measure cutting force, tool wear, chip figuration and surface roughness for different cutting conditions. As a result of study. Cutting depth influences on the cutting force much more than the feed rate and the value of the cutting force is the most stable at the depth of 1.0mm. And tool wear was serious at over 100m/min of cutting speed and cutting condition was excellent at 1.0mm of cutting depth.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1551-1554
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• 2005

The Titanium has many superior characteristics Which are specific strength, heat resistance, corrosion resistance, organism compatibility, non-magnetic and etc. and their quantity are abundant. this study performed turning operation of Ti-6Al-4V alloy using the TiAlN Coate Tool which treated PVD (Physical Vapor Deposition). Experimental works are also executed to measure cutting force, chip figuration and surface roughness for different cutting conditions. As a result of study. Tool wear was serious at over 100m/min of cutting speed and cutting condition was excellent at 1.0mm of cutting depth.