• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제8권12호
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• pp.473-482
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• 2019

이동 객체의 데이터 스트림으로부터 객체들의 궤적을 분석하는 연구는 이미 이루어진 바가 있다. 그 중 같이 움직이는 객체들의 그룹, 즉 동반 그룹을 찾는 연구도 이미 존재한다, 이들 대부분은 서로 가까이 존재하는 객체들의 그룹을 탐색하기 위해 기존의 클러스터링 기법을 사용한다. 하지만 클러스터링에 기반한 방법들은 정확한 클러스터의 수를 미리 알 수 없거나 클러스터의 모양이나 크기를 제어할 수 없기 때문에 정확한 동반 그룹을 찾기 어려운 경우가 많다. 본 논문은 실시간으로 유입되는 궤적 데이터 스트림에서 기존의 클러스터링 기법이 아니라 사용자가 지정한 거리를 기반으로 동반 그룹을 탐색하는 새로운 방법을 제안한다. 본 논문에서 제안하는 기법은 서로 가까이 존재하는 객체들의 그룹을 주기적으로 탐색하며, 이 때 사용자가 지정한 거리 내에 존재하는 객체들의 그룹을 매우 효율적으로 찾아내는 기법을 사용한다. 또한 동반 그룹 및 그의 궤적만을 반환하는 기존 방법과 달리 제안 방법은 동반 그룹의 생성 시간과 지속 시간도 같이 알려준다. 본 논문에서는 다양한 실험을 통해 제안 방법이 동반 그룹을 정확하고 매우 효율적으로 탐색할 수 있음을 보인다.

• Journal of Veterinary Science
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• 제22권2호
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• pp.17.1-17.13
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• 2021

Background: Klebsiella spp. is an important conditional pathogen in humans and animals. However, due to the indiscriminate use of antibiotics, the incidence of antimicrobial resistance has increased. Objectives: The purpose of this study was to investigate antimicrobial resistance in strains of Klebsiella strains and the phylogenetic relatedness of extended-spectrum cephalosporin (ESC)-resistance among Klebsiella strains isolated from clinically ill companion animals. Methods: A total of 336 clinical specimens were collected from animal hospitals. Identification of Klebsiella species, determination of minimum inhibitory concentrations, detection of ESC resistance genes, polymerase chain reaction-based replicon typing of plasmids by conjugation, and multilocus sequence typing were performed. Results: Forty-three Klebsiella strains were isolated and, subsequently, 28 were identified as K. pneumoniae, 11 as K. oxytoca, and 4 as K. aerogenes. Eleven strains were isolated from feces, followed by 10 from ear, 7 from the nasal cavity, 6 from urine, 5 from genitals, and 4 from skin. Klebsiella isolates showed more than 40% resistance to penicillin, cephalosporin, fluoroquinolone, and aminoglycoside. ESCresistance genes, CTX-M groups (CTX-M-3, CTX-M-15, and CTX-M-65), and AmpC (CMY-2 and DHA-1) were most common in the K. pneumoniae strains. Some K. pneumoniae carrying CTX-M or AmpC were transferred via IncFII plasmids. Two sequence types, ST709 and ST307, from K. pneumoniae were most common. Conclusions: In conclusion, this is the first report on the prevalence, ESCresistance genotypes, and sequence types of Klebsiella strains isolated from clinically ill companion animals. The combination of infectious diseases and antimicrobial resistance by Klebsiella in companion animals suggest that, in clinical veterinary, antibiotic selection should be made carefully and in conjunction with the disease diagnosis.

• Journal of Veterinary Science
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• 제21권1호
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• pp.16.1-16.10
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• 2020

Cancer is a major cause of death in dogs worldwide, and the incidence of cancer in dogs is increasing. The attenuated total reflection Fourier transform infrared spectroscopic (ATR-FTIR) technique is a powerful tool for the diagnosis of several diseases. This method enables samples to be examined directly without pre-preparation. In this study, we evaluated the diagnostic value of ATR-FTIR for the detection of cancer in dogs. Cancer-bearing dogs (n = 30) diagnosed by pathologists and clinically healthy dogs (n = 40) were enrolled in this study. Peripheral blood was collected for clinicopathological diagnosis. ATR-FTIR spectra were acquired, and principal component analysis was performed on the full wave number spectra (4,000-650 cm^-1). The leave-one-out cross validation technique and partial least squares regression analysis were used to predict normal and cancer spectra. Red blood cell counts, hemoglobin levels and white blood cell counts were significantly lower in cancer-bearing dogs than in clinically healthy dogs (p < 0.01, p < 0.01 and p = 0.03, respectively). ATR-FTIR spectra showed significant differences between the clinically healthy and cancer-bearing groups. This finding demonstrates that ATR-FTIR can be applied as a screening technique to distinguish between cancer-bearing dogs and healthy dogs.