• Child Health Nursing Research
• /
• v.8 no.2
• /
• pp.129-140
• /
• 2002

The article reports the process, contents and strategies in the development of community based-heath care management program for high-risk infants and family, which was based on literature review, empirical needs assessment from pilot study. The program was divided into two emphasis areas: (1) identification and home visiting nursing care program, and (2) the construction of self-supporting group. The contents of home visiting nursing care were developed from the pilot study of the direct home visiting to premature infants after discharge. The documentation form for home care was standardized, including the demographic data, birth history, home care services, education and counsels, and visiting schedules. The integrated education protocol was elaborated to enhance the body of knowledge as well as clinical competency in caring high-risk infants and family by the supports of neonatologists, nursing scholar, and clinical specialists. In addition, the process and strategies in developing self-supporting group, consisting the high-risk infants and family, and any significant others were addressed. Emphases were given to the role of public health center and the recycling health care referral system to maximize the growth and development of high-risk infants on the community-base, which in turn, contributing to decrease the postneonatal mortality rate.

• Journal of Korean Academy of Fundamentals of Nursing
• /
• v.18 no.3
• /
• pp.337-347
• /
• 2011

Purpose: Purposes of this study were to develop a community-based respite program for family caregivers and to test the effects of the program. Methods: Focus group interviews were performed to extract meaning of respite care for family caregivers (13 participants) and a survey was done to identify respite needs of family caregivers (157 participants). The community-based respite program for family caregivers was developed based on results of the focus group interview and survey. The program was used with 41 participants (19 experimental and 22 control). Independent t-test and Mann-Whitney U-test were used to test differences between control and experimental groups for respite needs, burden of caregivers, subjective wellbeing, social support, fatigue and functional status of elders with dementia. Results: There were statistical differences in caregiver burden, subjective wellbeing, and social support after the program, but, none for respite needs, fatigue and functional status of elders with dementia. Conclusion: The results indicate that a respite program can be useful to decrease burden of caregivers and increase subjective wellbeing and perceived social support of family caregivers in community settings. Further intervention research is needed to increase the functional status of elders with dementia and decrease fatigue in caregivers.

• Mass Spectrometry Letters
• /
• v.11 no.4
• /
• pp.113-117
• /
• 2020

Cytochrome P450 2J2 (CYP2J2) is a member of the cytochrome P450 superfamily, and is known to be arachidonic acid epoxygenase that mediates the formation of four bioactive regioisomers of epoxyeicosatrienoic acids (EETs). CYP2J2 is also involved in the metabolism of drugs such as albendazole, astemizole, danazol, ebastine, and terfenadine. CYP2J2 is highly expressed in the heart and cancer tissues. In this study, the inhibitory potential of ten natural products against CYP2J2 activity was evaluated using human liver microsomes and tandem mass spectrometry. Among them, bilobetin, which is a kind of biflavonoid, exhibits a strong inhibitory effect against the CYP2J2-mediated astemizole O-demethylation (IC50 = 0.73 μM) and terfenadine hydroxylation (IC50 = 0.89 μM). This result suggests that bilobetin can be used as strong CYP2J2 inhibitor in drug metabolism study.

• Mass Spectrometry Letters
• /
• v.13 no.4
• /
• pp.152-157
• /
• 2022

Schisandra chinensis and its fruits have been used as a traditional herbal medicine to treat liver dysfunction, fatigue, and chronic coughs. Several in vitro and in vivo studies suggested that dibenzocyclooctadiene lignans present in Schisandra fruits strongly inhibit CYP3A4 activity. However, reports on the inhibitory potential of dietary Schisandra supplements against CYP3A activity are limited despite their increasing consumption as dietary supplements. In this study, we evaluated the CYP3A-inhibitory potential of four dietary Schisandra supplements in human liver microsomes. At a concentration of 0.05 mg/mL, Schisandra supplements from Nature's Way, Swanson, Planetary Herbals, and Only Natural inhibited CYP3A activity by 93.9, 70.8, 33.6, and 24.8%, respectively. Nature's Way, which exhibited the strongest inhibition against CYP3A, had the highest contents of gomisin B and gomisin C, which potently inhibit CYP3A activity. The in vivo pharmacokinetics of this product should be examined to determine whether the clinical relevance of inhibiting CYP3A activity by dietary Schisandra supplementation.

• Journal of Agricultural Extension & Community Development
• /
• v.13 no.1
• /
• pp.123-134
• /
• 2006

The purpose of this study was to establish the effective model for community-centered youth development in Korea. The research methods used the extensive review of related literatures and consultation with a panel of experts in this field. Based on the major results, the implications and suggestions were as follows. First, community youth development will need to provide the opportunities of competencies and a full complement of positive connections to youth activities. Second, communities promote to engage youth as partners with adults in the process of positive youth development. Third, youth development organizations operate to support the programs to prevent or treat specific problems in terms of community youth contexts. Finally, collaboration and network are necessarily required among youth, adults, home, school, organizations within the community.

• Journal of Information Technology Applications and Management
• /
• v.12 no.4
• /
• pp.71-92
• /
• 2005

As the Internet establishes and reinforces connections between people, virtual community is becoming one of considerable business model. We believe that benefits of the virtual community go to both customer and vendor organizing virtual community. Despite the explosive growth of virtual communities on the Internet, empirical research has been focused to study the issues related to characteristics of virtual community The objective of this study is to enhance the understanding about virtual communities as an e-business model by Customer Relation Management and by empirically validating their effect on the performance of website. Through path analysis, we find support for relations behavior influence the online commitment. we also find that the online commitment enhance the organization citizenship behavior. Finally, we discuss several theoretical and practical Implications, and suggest limitations for research and future research issue.

• Journal of the Korean Society of Environmental Restoration Technology
• /
• v.8 no.4
• /
• pp.52-67
• /
• 2005

The flora of the studied basin in the upper Keum River was listed as 237taxa; 63families, 162genera, 212species, 22varieties and 3forms. Based on the list of the ecosystem disturbance plants by the Ministry of Environment, 4taxa were recorded in the studied basin : Paspalum distichum(Gramineae), Paspalum distichum var. indutum(Gramineae), Ambrosia artemisiifolia var. elatior(Compositae), Ambrosia trifida(Compositae). Naturalized plants was listed as 54taxa; 16families, 41genera, 51species, 3varieties and naturalization index was 22.8percent of 1/4 the vascular plants. Upper Keum River was dominant floristic : indicator species were Salix gracilistyla community, Phragmites japonica community, native plants were Morus alba community, Spiraea prunifolia for. simpliciflora community, planting plants were Populus euramericana community, naturalized plants were Solidago serotina community, Helianthus tuberosus community.

• Journal of Agricultural Extension & Community Development
• /
• v.15 no.3
• /
• pp.417-432
• /
• 2008

The purpose of this study were to discuss on the importance of community youth development programs and review the enhancement of competence in youth The research methods used the extensive review of related literatures. Based on the major results, the implications and suggestions were as follows. First, community youth activity will need to provide the opportunities of enhancing the competencies and a full complement of positive connections to youth programs. Second, communities promote to engage youth as partners with adults in the process of positive youth development. Third, youth development organizations operate to support the programs to prevent risky-behaviors or treat specific problems in terms of community youth contexts. Finally, collaboration and network are necessarily required among youth, adults, family, school, organizations within the community. Changes to work and workplace are so significant that policies refer to 'the knowledge society' at the same time 'information society'. Future workers will need to have the skills of information and communications management and control.

• The Journal of Information Technology
• /
• v.8 no.2
• /
• pp.1-16
• /
• 2005

In high education, knowledge is the very important resource and output. Knowledge management is the art of creating additional value from academic knowledge assets. The e-community is the network community, newly created by information communication technology, and the critical place that share and transfer people's the various knowledge and thinking and the effective space that can apply knowledge management. If we construct a convenient and useful e-community in our university, we will be able to increase the student's intellectual needs, and create new knowledge. Web-portal will promote the activity of e-community providing easy to access and personalized web circumstance. The emergence of Internet and Web access to all university services will force institutions to rethik everything. We should reconfigure our academic environment in order to adapt information technology and educational change, and must do change management based on their structure and culture.

• Journal of Agricultural Extension & Community Development
• /
• v.4 no.1
• /
• pp.15-27
• /
• 1997

This paper reviews the concept and limits of rural community development, examines the relation between consciousness education and movement, and suggests the model of social consciousness education to rural community movement. Since consciousness education is closely related to social movement methodologically, organizational and systematic community development movements for re-structuring the urban-oreiented policies and education which back up them be followed as natural consequence. Based upon the results of this study, the new paradigm is suggested. As shown in the model, new understanding of urban-rural continuum theory, new roles and concept of social consciousness education should be emphasized to solve the contemporary rural community problems. The organizational community development movement for the rural-oriented policy should be an essential process, and peoples' re-orientation, such as 'breaking stereotype', 'assumming a critical thinking toward social reality' etc., is the indispensible background of successful movement.