• 제목/요약/키워드: Commercial Practice

검색결과 330건 처리시간 0.024초

Plant Molecular Farming Using Oleosin Partitioning Technology in Oilseeds

  • Moloney, Maurice-M.
    • 식물조직배양학회지
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    • 제24권4호
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    • pp.197-201
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    • 1997
  • Plant seed oil-bodies or oleosomes ate the repository of the neutral lipid stored in seeds. These organelles in many oilseeds may comprise half of the total cellular volume. Oleosomes are surrounded by a half-unit membrane of phospholipid into which are embedded proteins called oleosins. Oleosins are present at high density on the oil-body surface and after storage proteins comprise the most abundant proteins in oilseeds. Oleosins are specifically targeted and anchored to oil-bodies after co-translation on the ER. It has been shown that the amino-acid sequences responsible for this unique targeting reside primarily in the central hydrophobic tore of the oleosin polypeptide. In addition, a signal-like sequence is found near the junction of the hydrophobic domain and ann N-terminal hydrophilic / amphipathic domain. This "signal" which is uncleaved is also essential for correct targeting. Oil-bodies and their associated oleosins may be recovered by floatation centrifugation of aqueous seed extracts. This simple partitioning step results in a dramatic enrichment for oleosins in the oil-body fraction. In the light of these properties, we reasoned that it would be feasible to create fusion proteins on oil-bodies comprising oleosins and an additional valuable protein of pharmaceutical or industrial interest. It was further postulated that if these proteins were displayed on the outer surface of oil-bodies, it would be possible to release them from the purified oil-bodies using chemical or proteolytic cleavage. This could result in a simple means of recovering high-value protein from seeds at a significant (i.e. commercial) scale. This procedure has been successfully reduced to practice for a wide variety of proteins of therapeutic, industrial and food no. The utillity of the method will be discussed using a blood anticoagulant, hirudin, and industrial enzymes as key examples.

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UNCITRAL 중재규칙 개정안의 내용과 쟁점에 관한 연구 (A Study on the Draft and Issues for the Revision of UNCITRAL Arbitration Rules)

  • 이강빈
    • 한국중재학회지:중재연구
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    • 제17권2호
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    • pp.43-70
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    • 2007
  • The purpose of this paper is to make research on the contents and discussions of the draft of revised UNCITRAL Arbitration Rules that have been discussed and considered by the Working Group. At its thirty-ninth session (New York, 19 June-7 July 2006), the Commission agreed that, in respect of future work of the Working Group, priority be given to a revision of the UNCITRAL Arbitration Rules (1976). At its forty-fifth session (Vienna, 11-15 September 2006), the Working Group undertook to identify areas where a revision of the UNCITRAL Arbitration Rules might be useful. At that session, it was considered that the focus of the revision should be on updating the Rules to meet changes that had taken place over the last thirty years in arbitral practice. The largely amended provisions of the draft of revised UNCITRAL Arbitration Rules are as follows : Notice of arbitration and response to the notice of arbitration (Article 3), Designating and appointing authorities (Article 4 bis), November of arbitrators (Article 5), Appointment of arbitrations (Article 6), Appointment of arbitrators in multi-party arbitration (Article 7 bis), Challenge of arbitrators (Article 9), Replacement of an arbitrator (Article 13), Pleas as to the jurisdiction of the arbitral tribunal (Article 21), Interim measures (Article 26), Form and effect of the award (Article 32), and Liability of arbitrators (Proposed additional provisions). There are some differences between the draft of revised UNCITRAL Arbitration Rules and the KCAB Arbitration Rules. In order to jnternationalize the Korea's commercial arbitration system, it is desirable that the main articles of the draft of revised UNCITRAL Arbitration Rules should be admitted to the KCAB Arbitration Rules. In conclusion, the Commission was generally of the view of any revision of the UNCITRAL Arbitration Rules should not alter the structure of the text, its spirit, its drafting style, and should respect the flexibility of the text rather than make it more complex. The Working Group agreed that harmonizing the provisions of the UNCITRAL Model Law should not be automatic but rather considered only where appropriate.

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유도 결합 구조를 응용한 UHF 대역 Near-Isotropic 태그 안테나 (Near-Isotropic Tag Antenna in UHF band Using Inductively Coupled Feeding)

  • 안준오;장형민;문효상;이범선
    • 한국전자파학회논문지
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    • 제17권12호
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    • pp.1240-1248
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    • 2006
  • 본 논문에서는 유도 결합 구조를 응용하여 등방향 방사 특성에 근접하고 기 상용화된 태그 칩과의 임피던스 매칭과 제작이 용이한 UHF(911 MHz) 대역 RFID 태그 안테나를 설계 제작하였다. 제안된 안테나는 $40{\times}46mm\;(0.12{\times}0.14{\lambda})$의 크기를 가지고 수직 입사의 경우에 최대 RCS가 $-18.5dBm^2$이며, 3 dB RCS 대역폭이 9 MHz(1%)이다. 태그 칩과 안테나 임피던스가 단락 상태일 때의 RCS가 방향에 따라 최대 $-16.9dBm^2$, 최소 $-21.4dBm^2$로 4.5 dB의 차이를 보여, 기존 다이폴 형태의 안테나가 가지는 입사파의 방향에 따른 문제점을 대폭 개선하였다. 또한 설계된 안테나를 제작하여 입사파 각도에 따른 RCS를 측정하였고, 시뮬레이션 결과와 유사함을 확인하였다.

INCOTERMS 2000과 비용부담원칙(費用負擔原則) (Incoterms 2000 and Main Principle of Division of Costs)

  • 박남규
    • 무역상무연구
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    • 제13권
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    • pp.3-26
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    • 2000
  • The International Chamber of Commerce published the millennium edition of its standard trade definitions, Incoterms 2000. Incoterms are a basic reference for sales contracts, in constant daily use throughout the world. The new version will make it easier for traders to do business in the new century, despite the growing volume and complexity of international transactions. Since Incoterms were first published in 1936, they have been updated six times. They precisely define the responsibilities of buyer and seller and are recognized as the international standard by customs authorities and courts in all the main trading nations. It is important for traders to incorporate the correct Incoterms into their international contracts to avoid unnecessary legal problems. Courts may otherwise interpret trade terms according to often widely divergent national laws and unless the use of Incoterms is specified, expensive legal disputes can arise. Division of costs is a most important element in every contract of sale. The parties must know not only who does what but also how costs resulting therefrom should be divided between them. In most cases the fact that a party must do something means that he must also bear the resulting costs, unless otherwise agreed. But there are many exceptions to this principle and uncertainties arise, particularly with respect to services performed by other parties. Also, difficulties arise with respect to the division of costs whenever additional costs are caused by unexpected events, such as hindrances causing a ship to deviate or to remain in a seaport longer than expected. The main principle of the division of costs is clear enough: the seller has to pay costs necessary for the goods to reach the agreed point of delivery, and the buyer has to pay any further costs after that point. But as noted, it is not always easy to implement this principle in practice, since the detailed distribution of functions under the various trade terms is not and cannot be fully defined in Incoterms. Instead, failing precise stipulations in the contract of sale, guidance must be sought from other criteria such as commercial practices used earlier by the same parties or the custom of trade.

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Protein quality, hematological properties and nutritional status of albino rats fed complementary foods with fermented popcorn, African locust bean, and bambara groundnut flour blends

  • Ijarotimi, Oluwole Steve;Keshinro, Oluremi Olufunke
    • Nutrition Research and Practice
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    • 제6권5호
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    • pp.381-388
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    • 2012
  • The objective of this study was to determine protein quality and hematological properties of infant diets formulated from local food materials. The food materials were obtained locally, fermented, and milled into flour. The flours were mixed as 70% popcorn and 30% African locust bean (FPA), 70% popcorn and 30% bambara groundnut (FPB), and 70% popcorn, 20% bambara groundnut, and 10% African locust bean (FPAB). Proximate analysis, protein quality, hematological properties, and anthropometric measurements of the animals fed with the formulations were investigated. The protein contents of the formulated diets were significantly higher than that of Cerelac (a commercial preparation) ($15.75{\pm}0.01g$/100 g) and ogi (traditional complementary food) ($6.52{\pm}0.31g$/100 g). The energy value of FPAB ($464.94{\pm}1.22\;kcal$) was higher than those of FPA ($441.41{\pm}3.05\;kcal$) and FPB ($441.48{\pm}3.05\;kcal$). The biological value (BV) of FPAB (60.20%) was the highest followed by FPB (44.24%) and FPA (41.15%); however, BV of the diets was higher than that of ogi (10.03%) but lower than that of Cerelac (70.43%). Net protein utilization (NPU) of the formulations was 41.16-60.20%, whereas true protein digestibility was 41.05-60.05%. Metabolizable energy (232.98 kcal) and digestible energy (83.69 kcal) of FPAB were the highest, whereas that of FPA had the lowest values. The protein digestibility values corrected for amino acid score of the diets (0.22-0.44) were lower than that of Cerelac (0.52), but higher than that of ogi (0.21). The growth patterns and hematological properties (packed cell volume, red blood cells, hemoglobin, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, and mean corpuscular volume) of the formulated diets were higher than those of ogi, but lower than those of Cerelac. In conclusion, we established that the FPAB food sample was rated best in terms of protein quality over the other formulated diets. Therefore, a FPAB blend may be used as a substitute for ogi.

일부 다빈도 질환에서 개원의의 의약품 처방에 영향을 미치는 요인 (Factors Influencing Physicians' Prescriptions in Some Frequent Diseases)

  • 박실비아;문옥륜;강영호
    • 보건행정학회지
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    • 제8권2호
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    • pp.166-190
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    • 1998
  • This study presents the status on drug prescription for clinic outpatients' bronchitis, gastritis, and gastric ulcer, and also the physician factors that affects their prescriptions. In this research project the physician factors are as follows: their demographic features, their work related features, education related features, drug information related features and drug promotion related features. The variables in drug prescriptions are drug expenses, daily drug expenses, days of medication, the highest price of the drugs used and the number of the different drugs used. Analysis of the use of prescription drugs was performed on NFMI(National Federation of Medical Insurance) 1994 medical expense claim data. Data on physicians' characteristics were collected by mailing surveys. Patients with secondary diseases were excluded. In this study, 388 adults with bronchitis, 1,038 children with bronchitis, 1,158 patients with gastritis, 369 patients with gastric ulcer were included. The older physicians tend to allow the lower drug costs: this explains that the older doctors who are more experienced less depend on the medicines. It can be also explained that doctors are likely to use the medicines that had been used for their intern and resident practice/training period. General practitioners give more intensive prescription compared to specialists. And specialists prescribed medicines to patients for longer period. The doctors' prescriptions for patients are largely affected by commercial sources. So objective and reliable sources for drug information is needed for patients' benefits. Physician factors explain better at the daily drug expenses, the drug price and the number of different drugs than days of medication. Gastric ulcer are better explained by the prescription model adopted in this study than other diseases.

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환승센터내 환승정보서비스를 위한 정보연계 표준화 연구 (A Study on the Standardization of Information Connection for Transfer Information Service in Transfer Center)

  • 배명환;오동섭;이승환;오세창
    • 대한교통학회지
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    • 제29권5호
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    • pp.33-42
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    • 2011
  • 환승센터의 규모가 점차 대형화됨에 따라 대규모 환승센터에서 동적으로 이동하는 이용자의 편의를 고려한 환승정보서비스가 필요하다. 이러한 서비스는 동적으로 이동하는 이용자에게 무선통신이 가능한 개인 휴대단말기(Mobile phone, Smart phone)를 통해 환승정보제공을 가능하게 한다. 특히, Wi-Fi를 이용한 실내위치측위 기술은 실용화 단계로서 GPS와 Wi-Fi를 탑재한 Smart phone을 통해서는 실내외 위치기반 환승정보서비스가 가능하다. 따라서, 본 연구에서는 환승센터에서 환승센터 내부 이용객의 위치를 기반으로 하는 환승정보의 제공과 환승활동을 지원하는 정보제공서비스를 제시하였으며, 이러한 환승정보서비스를 위해 필요한 논리/물리 아키텍처 및 물리적 구성요소의 정보흐름의 제시와 정보연계 표준화 대상을 도출하여 각 표준화 대상에 대한 정보연계 표준안을 제시하였다.

Energy intake from commercially-prepared meals by food source in Korean adults: Analysis of the 2001 and 2011 Korea National Health and Nutrition Examination Surveys

  • Choi, Injoo;Kim, Won Gyoung;Yoon, Jihyun
    • Nutrition Research and Practice
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    • 제11권2호
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    • pp.155-163
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    • 2017
  • BACKGROUND/OBJECTIVES: The commercial foodservice industry in Korea has shown rapid growth recently. This study examined Korean adults' consumption of commercially-prepared meals based on where the food was prepared. SUBJECTS/METHODS: Data from a 24-hour dietary recall of the 2001 and 2011 Korea National Health and Nutrition Examination Surveys were analyzed. A total of 10,539 subjects (n = 6,152 in 2001; n = 4,387 in 2011) aged 19-64 years were included for analysis. Commercially-prepared meals were classified into four food source groups based on where the food was prepared: Korean restaurants, Chinese/Western/Japanese restaurants, fast-food restaurants, and retail stores. Subjects' energy intake, including the amount and proportion of calories, was examined for each food source. The analysis was also conducted by gender for age-stratified groups: 19-29, 30-49, and 50-64 years old. RESULTS: Korean adults' energy intake from commercially-prepared meals increased in the amount of calories (551 kcal to 635 kcal, P < 0.01), but not in the proportion of daily calories (27% to 28%) from 2001 to 2011. The most frequent food source of commercially-prepared meals was Korean restaurants in both years. The amount and proportion of calories from retail stores increased from 83 kcal to 143 kcal (P < 0.001) and from 4% to 7% (P < 0.001), respectively, during the same period. Males aged 30-49 years (34%) and females aged 19-29 years (35%) consumed the highest proportion of daily calories from commercially-prepared meals in 2011. CONCLUSIONS: Korean adults consumed about one-fourth of their energy intake from commercially-prepared meals. In particular, males aged 30-49 years and females aged 19-29 years consumed more than one-third of their energy intake from commercially-prepared meals. Korean restaurants played a significant role in Korean adults' energy intake. Retail stores increased influence on Korean adults' energy intake. These results could be useful for developing health promotion policies and programs.

Shape memory alloy (SMA)-based head and neck immobilizer for radiotherapy

  • Lee, Hyun-Taek;Kim, Sung-In;Park, Jong Min;Kim, Ho-Jin;Song, Dae-Seob;Kim, Hyung-Il;Wu, Hong-Gyun;Ahn, Sung-Hoon
    • Journal of Computational Design and Engineering
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    • 제2권3호
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    • pp.176-182
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    • 2015
  • Head-and-neck cancer is often treated with intensive irradiation focused on the tumor, while delivering the minimum amount of irradiation to normal cells. Since a course of radiotherapy can take 5-6 weeks or more, the repeatability of the patient posture and the fastening method during treatment are important determinants of the success of radiotherapy. Many devices have been developed to minimize positional discrepancies, but all of the commercial devices used in clinical practice are operated manually and require customized fixtures for each patient. This is inefficient and the performance of the fixture device depends on the operator's skill. Therefore, this study developed an automated head-and-neck immobilizer that can be used during radiotherapy and evaluated the positioning reproducibility in a phantom experiment. To eliminate interference caused by the magnetic field from computed tomography hardware, Ni-Ti shape-memory alloy wires were used as the actuating elements of the fixtures. The resulting positional discrepancy was less than 5 mm for all positions, which is acceptable for radiotherapy.

박막 요소를 이용한 스피커 그릴 일체형 맵 포켓의 사출 성형 해석 (Injection Molding Analysis of Map Pocket with a Speaker Grill Using Shell Element)

  • 김홍석;조명상;손중식;서태수;김태웅
    • 대한기계학회논문집A
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    • 제25권8호
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    • pp.1294-1301
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    • 2001
  • In order to reduce the time and cost for assembly, automobile speaker grills have been injection molded with door trims or map pockets in one piece recently. However, several defects such as short shots or air traps can easily occur due to the decreased fluidity of the melting polymer according to the excessive heat transfer to the mold. Therefore, it is necessary to optimize the resin feed system and predict possible defects by CAE analysis. However it is not possible to obtain exact analysis results for the speaker grill by using general shell elements since the heat transfer in the thickness direction which is the dominant factor of the filling stage can not be considered. Therefore, there have been several efforts to simulate the injection molding nature of the speaker grill by using shell elements with an effective thickness which is smaller than the actual thickness of the part. Two empirical values have been recommended for the effective thickness in real practice. One is 50∼70% of the thickness of the speaker grill and another is the gap distance between the adjacent holes. In this paper, CAE analyses of a map pocket with a speaker grill were conducted using shell elements with both of these recommended effective thicknesses, and the predicted flow fronts were compared with the findings from injection molding experiments. The commercial code MOLDFLOW was used for injection molding analysis and an 850 ton injection molding machine was used for experiments.