• Title/Summary/Keyword: Combined sequence

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Metal-Poor F-G-K type Local Subdwarfs From SDSS + GAIA GR2: Spectrophotometric & Kinematic Properties

  • Yang, Soung-Chul;Kim, Young Kwang;Lee, Young Sun;Lee, Hogyu
    • 천문학회보
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    • 제43권2호
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    • pp.59.2-59.2
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    • 2018
  • We introduce a new project of constructing a large spectro-photometric samples of metal-poor (i.e. [Fe/H] < -1.0) subdwarfs in the Galactic halo. The sample is collected from a compilation of the stellar objects that are cross-identified both in the Sloan Digital Sky Survey (SDSS) and recently published data from GAIA mission. The color range of the selected stars covers 0.0 < (g-r) < 2.0; thus the spectral types of our sample span from early F- through late K-type stars on the metal-poor main sequence (i.e. the local subdwarf sequence). We scrutinized the physical, chemical, and kinematical properties of our samples using their SDSS medium-resolution (R ~ 2000) spectra, combined with accurately measured proper motions from GAIA satellite. Our study will provide useful information on the global trend in the various properties (e.g. abundance pattern as a function of the galactocentric distance; rotational velocity vs [Fe/H] ${\cdots}$ etc) of the metal-poor subdwarf populations in the Galactic halo, which is ultimately important to better understand metal-poor stellar evolutionary models and chemical evolution of the Milky Way halo in the early phase of its formation. Further our comprehensive catalog of the Galactic field halo subdwarfs collected in this study will serve a solid groundwork for future follow-up high resolution spectroscopic observations on many interesting individual targets.

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Flanking Sequence and Copy-Number Analysis of Transformation Events by Integrating Next-Generation Sequencing Technology with Southern Blot Hybridization

  • Qin, Yang;Woo, Hee-Jong;Shin, Kong-Sik;Lim, Myung-Ho;Cho, Hyun-Suk;Lee, Seong-Kon
    • Plant Breeding and Biotechnology
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    • 제5권4호
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    • pp.269-281
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    • 2017
  • With the continual development of genetically modified (GM) crops, it has become necessary to develop detailed and effective molecular characterization methods to select candidate events from a large pool of transformation events. Relative to traditional molecular analysis methods such as the polymerase chain reaction (PCR) and Southern blot hybridization, next generation sequencing (NGS) technology for whole-genome sequencing of complex crop genomes had proven comparatively useful for in-depth molecular characterization. In this study, four transformation events, including one in Bacillus thuringiensis (Bt)-resistant rice, one in resveratrol-producing rice, and two in beta-carotene-enhanced soybeans, were selected for molecular characterization. To merge NGS analysis and Southern blot-hybridization results, we confirmed the transgene insertion sites, insertion construction, and insertion numbers of these four transformation events. In addition, the read-coverage depth assessed by NGS analysis for inserted genes might provide consistent results in terms of inserted T-DNA numbers in case of complex insertion structures and highly duplicated donor genomes; however, PCR-based methods can produce incorrect conclusions. Our combined method provides an effective and complete analytical approach for whole-genome visual inspection of transformation events that require biosafety assessment.

A Hierarchical Bilateral-Diffusion Architecture for Color Image Encryption

  • Wu, Menglong;Li, Yan;Liu, Wenkai
    • Journal of Information Processing Systems
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    • 제18권1호
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    • pp.59-74
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    • 2022
  • During the last decade, the security of digital images has received considerable attention in various multimedia transmission schemes. However, many current cryptosystems tend to adopt a single-layer permutation or diffusion algorithm, resulting in inadequate security. A hierarchical bilateral diffusion architecture for color image encryption is proposed in response to this issue, based on a hyperchaotic system and DNA sequence operation. Primarily, two hyperchaotic systems are adopted and combined with cipher matrixes generation algorithm to overcome exhaustive attacks. Further, the proposed architecture involves designing pixelpermutation, pixel-diffusion, and DNA (deoxyribonucleic acid) based block-diffusion algorithm, considering system security and transmission efficiency. The pixel-permutation aims to reduce the correlation of adjacent pixels and provide excellent initial conditions for subsequent diffusion procedures, while the diffusion architecture confuses the image matrix in a bilateral direction with ultra-low power consumption. The proposed system achieves preferable number of pixel change rate (NPCR) and unified average changing intensity (UACI) of 99.61% and 33.46%, and a lower encryption time of 3.30 seconds, which performs better than some current image encryption algorithms. The simulated results and security analysis demonstrate that the proposed mechanism can resist various potential attacks with comparatively low computational time consumption.

일-생활 균형 관점에서 본 기혼남녀의 시간표 : 부부결합 가구노동시간 유형에 따른 남녀의 일-생활시간의 비교분석 (Investigating daily schedules of married couple by focusing on work-life balance : Comparison of work-life time by gender according to couple-combined work schedules)

  • 조미라
    • 사회복지연구
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    • 제49권2호
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    • pp.5-38
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    • 2018
  • 본 연구는 한국사회 기혼남녀의 일-생활 균형의 문제를 시간표 분석을 통해 파악하는 것을 목적으로 한다. 이를 위해 2014년도 통계청 생활시간조사 시간대자료를 이용하여 3,131쌍 기혼부부의 6,262개의 시간일지를 분석하였다. 분석 방법으로는 시간양뿐 아니라 시간배치를 고려한 전체적인 분석을 위해 배열분석을 사용하였으며, 이때 Lesnard(2014)의 DHM(Dynamic Hamming Matching) 방식으로 배열 간 거리를 산출하여 타이밍을 중시하는 시간분석에 무리가 없도록 조치하였다. 구체적으로는, 군집분석을 통해 도출된 부부결합의 가구노동시간 9개 유형별로, 남녀 각각의 노동, 가사, 수면, 자기관리, 적극적 여가, 소극적 여가, 기타로 구성된 일과 생활시간의 평균시간양과 시간대별 분포와 최빈상태의 그래프를 산출하여 해석하였다. 이러한 분석결과를 종합하여, 일-생활 불균형된 시간구성의 특성으로 '만연된 장시간노동', '젠더불평등한 시간배분', '비표준시간대 노동으로 인한 삶의 질 하락', '여가시간의 부족'을 지목하였으며, 마지막으로는 이러한 결과에 기초해 일-생활 균형을 높이기 위한 사회복지의 실천적 정책적 함의를 논의하고 후속연구를 제언하였다.

지표수로부터 세포배양-연계 PCR법에 의한 장바이러스의 검출 (Detection of Enterovituses from Surface Water by Combined Cell Culture-PCR)

  • 정은영;정종문;류재익;신판세;전홍기;장경립
    • 생명과학회지
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    • 제10권5호
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    • pp.484-489
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    • 2000
  • Enterovirues may cause gastrointestinal symptoms, cold, and fever, mainly in young children. They are also recognized as important agents in acute infections of the central nervous system such as meningitis and encephalitis, and in subacute and chronic infections of the cardiovascular system such as pericarditis, myocarditis and cardiomyopathy. They also can lead to postviral fatigue syndrome. For the detection of enteroviruses from the environmental samples, the combined cell culture-polymerase chain reaction (CC-PCR) technique was employed. In contrast to EPA standard method which mainly depends on the cell culture, it involved the use of cell culture, followed by PCR to improve the sensitivity and the accuracy of the test. According to the results of survey, from 1999 to 2000, for the presence of enteroviruses in the surface water samples from Nak-dong river, four out of twelve samples were positive for viruses. The titer of viruses in the surface water was ranged from 25 to 250 MPN. All of the viruses isolated were poliovirus type I with 98% nucleotide sequence homology. The result also clearly suggests the seasonal difference in the distribution of the waterborne enteroviruses in surface water because most of the viruses were mainly detected from the summer through the early autumn.

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Genetic Risk Prediction for Normal-Karyotype Acute Myeloid Leukemia Using Whole-Exome Sequencing

  • Heo, Seong Gu;Hong, Eun Pyo;Park, Ji Wan
    • Genomics & Informatics
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    • 제11권1호
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    • pp.46-51
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    • 2013
  • Normal-karyotype acute myeloid leukemia (NK-AML) is a highly malignant and cytogenetically heterogeneous hematologic cancer. We searched for somatic mutations from 10 pairs of tumor and normal cells by using a highly efficient and reliable analysis workflow for whole-exome sequencing data and performed association tests between the NK-AML and somatic mutations. We identified 21 nonsynonymous single nucleotide variants (SNVs) located in a coding region of 18 genes. Among them, the SNVs of three leukemia-related genes (MUC4, CNTNAP2, and GNAS) reported in previous studies were replicated in this study. We conducted stepwise genetic risk score (GRS) models composed of the NK-AML susceptible variants and evaluated the prediction accuracy of each GRS model by computing the area under the receiver operating characteristic curve (AUC). The GRS model that was composed of five SNVs (rs75156964, rs56213454, rs6604516, rs10888338, and rs2443878) showed 100% prediction accuracy, and the combined effect of the three reported genes was validated in the current study (AUC, 0.98; 95% confidence interval, 0.92 to 1.00). Further study with large sample sizes is warranted to validate the combined effect of these somatic point mutations, and the discovery of novel markers may provide an opportunity to develop novel diagnostic and therapeutic targets for NK-AML.

적층배열 변화에 따른 진동하는 복합재료 적층 구조의 미시역학적 물성변화 추정 (Determination of Degraded Properties of Vibrating Laminated Composite Plates for Different Layup Sequences)

  • 김규동;이상열
    • Composites Research
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    • 제28권5호
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    • pp.277-284
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    • 2015
  • 본 연구의 목적은 고유진동 응답데이터로부터 적층된 GFRP 판구조의 섬유 물성 변화를 추정하는 것이다. 고등유한요소 상용프로그램(ABAQUS)와 연동된 알고리즘은 미시역학적 관점에서 손상된 요소를 추정할 뿐만 아니라 위치, 개수 및 정도를 탐색할 수 있다. 연동된 기법을 적용하여 역문제를 해결하기 위하여 본 연구에서는 모드형상 대신 제한된 몇 개의 고유진동수 데이터만을 적용하였다. 몇가지 수치해석 결과로부터 제안된 시스템 기법은 다양한 적층배열을 갖는 복합재료 적층판과 같은 복잡한 구조물의 섬유 강성 변화를 추정하는 데 수치해석적으로 효율적임을 보여준다.

성능함수제어 알고리즘을 이용한 3상 4선식 하이브리드형 직렬능동전력필터 (Hybrid Series Active Power filter Based on Performance Function Theory for 3-Phase 4-wire System)

  • 김진선;신재화;김영석
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2003년도 하계학술대회 논문집 B
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    • pp.1096-1098
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    • 2003
  • In this paper, the control algorithm and control methods for a combined system of shunt passive filter and series active filter in 3-phase 4-wire system are discussed. Moreover, the 3-phase 4-wire system is widely employed in distributing electric energy to several office building and manufacturing plants. In such systems, the third harmonic and odd multiples of $3^{rd}$($9^{th}$, $15^{th}$, etc.) are termed as triple and zero sequence components that do not cancel each other in the system neutral. As a result, the triple harmonics add together creating a primary source of excessive neutral current. Regarding this concern, this paper presents a new control scheme for a series hybrid active system. This series active power filter acts not only as a harmonic compensator but also as a harmonic isolator. Hence the required rating of the series active filter is much smaller than that of a conventional shunt active filter. However, the performance of the combined system is greatly influenced by the filtering algorithm employed in the active power filter. This paper proposes a series active power filter scheme based on performance function. Some experiments was executed and experimental results from a prototype active power filter confirm the suitability of the proposed approach.

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고속 버스트 모뎀을 위한 MSDD Diversity 수신 알고리즘 (The MSDD Diversity Receiver Algorithm for a High Speed Burst Modem)

  • 김재형;이영철
    • 한국정보통신학회논문지
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    • 제8권2호
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    • pp.281-288
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    • 2004
  • 본 논문에서는 저속 페이딩 환경 하에서 다중 심볼 차동 복조기의 다이버시티 수신 방법에 대하여 연구한다. MSDD(Multiple Symbol Differential Detection)를 이용하여 다이버시티 수신을 할 경우 복조 블럭의 길이를 크게 할수록 차동 부호화된 MPSK의 Maxim -Ratio-Combining(MRC) 다이버시티 수신기 성능에 수렴하지만 복잡도가 지수적으로 증가하여 현실적으로 구현이 불가능하다. 본 논문에서는 MSDD 수신기에 입력하기 전에 수신 신호들을 정렬 시켜서 결합하는 pre-combining 방식을 제안하였다. 여기서 제안된 pre-combined MSDD 다이버시티 수신기는 준최적 수신기로서 수신기의 복잡도가 복조 블록의 길이에 선형적으로 증가하는 효율적인 MSDD 복조를 가능케 한다. 따라서 고속의 버스트 모뎀과 같이 동기 복조의 어려움이 있을 경우, 채널에 대한 정보에 의존치 않고도 다이버시티 수신을 할 수 있으며 기존의 차동 복조 방식에 비하여 큰 성능 향상을 보여준다.

Orthodontic tooth movement after periodontal regeneration of intrabony defects

  • Conchita Martin;Mariano Sanz
    • 대한치과교정학회지
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    • 제54권1호
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    • pp.3-15
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    • 2024
  • The prevalence of intrabony defects in patients with advanced periodontitis stages III and IV is high. These patients usually need both periodontal treatment and orthodontic therapy, including tooth movement through bone defects, to improve masticatory function, aesthetics, and overall quality of life. Clinical practice guidelines recommend periodontal regenerative surgical interventions to resolve these defects and propose initiating orthodontic tooth movement (OTM) once periodontal therapy goals have been met. Surgical interventions using various regenerative technologies like barrier membranes and enamel matrix proteins, combined or not with bone replacement grafts, have proven effective in regenerating lost periodontal tissues. However, the combination of periodontal and orthodontic treatments requires consideration of how periodontal regenerative therapies influence OTM. Studies suggest that regenerated bone may differ in density, composition, vascularity, and cellular activity, potentially affecting the speed and efficiency of OTM, and potential root resorption of moved teeth. Understanding the sequence and timing of implementing OTM after regenerative periodontal interventions is crucial due to their interlinked processes of bone resorption and formation. This narrative review aims to uncover scientific evidence regarding these combined treatments, examining the impacts of different regenerative technologies on OTM and delineating their advantages, limitations, and best practices.