• 대한약침학회지
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• 제8권2호
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• pp.83-90
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• 2005

Objective : This study was performed to compare needle acupuncture combined herbal acupuncture therapy with only needle acupuncture therapy in VAS and pain threshold. Methods : We used pressure algometer to evaluate the change of pain threshold before and after treatment. The numberical value of pressure algometer is obtained twice and averaged by identical acupuncturist. Visual analogue scale(VAS) was used to estimate the efficacy of needle acupuncture combined herbal acupuncture therapy. Result : The following results were obtained; 1. The significant difference in VAS was showed before and after treatment in only needle acupuncture therapy. 2. The significant difference in pain threshold and VAS was showed before and after treatment in needle acupuncture combined herbal acupuncture therapy. 3. In the pain threshold, the significant difference between only needle acupuncture and needle acupuncture combined herbal acupuncture therapy was not showed. 4. Needle acupuncture combined herbal acupuncture therapy showed the more effective change of VAS than only needle acupuncture therapy. Conclusions : In the pain control, needle acupuncture combined herbal acupuncture therapy is more effective than only needle acupuncture therapy.

• 산업융합연구
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• 제21권12호
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• pp.75-81
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• 2023

본 연구는 노인건강증진을 위한 복합운동프로그램의 효과 검증에 있다. 이를 위해 65세 이상 노인을 대상으로 운동군 10명과 통제군 10명을 선정하였다. 본 연구의 처치프로그램은 12주간 복합운동프로그램으로 유산소운동과 무산소운동을 주 3회 60일간 실시하였다. 운동 참여 전에 혈중지질과 염증지표 검사를 실시하였으며 복합운동프로그램을 종료하면서 혈중지질과 염증지표 검사를 재 실시하였다. 검사결과는 SPSS통계프로그램을 이용하여 기초통계와 집단간의 처치효과를 검증하였다. 이를 기본으로 이와 같은 결과 및 결론을 얻었다. 첫째, 노인건강증진을 위한 복합운동프로그램은 운동군과 통제군의 혈중지질에서 TC, LDL, TG에서 유의미한 차이를 나타내었으며, 처치프로그램에 대한 상호작용효과가 있었다. 둘째, 노인건강증진을 위한 복합운동프로그램은 운동군과 통제군의 염증지표에서 IL-6, TNF-a에서 유의미한 차이를 나타내었으며, 처치프로그램 대한 상호작용효과가 있었다.

• Medical Lasers
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• 제8권2호
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• pp.94-96
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• 2019

Burns are one of the most extensive injuries of soft tissues as well as skin, occasionally resulting in extensive, deep wounds and death. Burn wounds can lead to severe physical and psychological distress because of excessive scarring and skin contractures. Treatment of burn wounds has always been a challenging problem and many different methods have been used to treat such injuries. We report here on treating a patient with a burn wound using 830-nm light emitting diode (LED) phototherapy combined with epidermal growth factor (EGF) solution. After five daily sessions of LED with EGF solution treatment, the patient demonstrated nearly complete improvement with no remarkable side effects. We suggest that LED phototherapy combined with EGF solution could be an effective and safe treatment option for treating burn wounds.

• 한국식품영양과학회지
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• 제40권2호
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• pp.245-252
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• 2011

신선 채소 중 레드 치커리와 청경채의 미생물학적 안전성 확보를 위해 50 ppm 이산화염소수와 10 kJ/$m^2$ UV-C 조사 병합 처리에 따른 저장 중 미생물 수 및 품질 변화에 미치는 영향을 처리 후 $4{\pm}1^{\circ}C$에서 7일 동안 저장하면서 실험하였다. 레드 치커리와 청경채의 총 호기성 세균 수는 대조구와 비교 시, 이산화염소수와 UV-C 병합 처리구에서 2.64, 2.55 log CFU/g 감소시켰으며, 효모 및 곰팡이는 2.41, 2.00 log CFU/g 감소시켰다. 또한, 레드 치커리와 청경채의 저장 7일 후, 이산화염소수와 UV-C 병합 처리구의 총 호기성 세균수는 3.71, 3.93 log CFU/g으로 대조구와 비교할 때, 2.60, 2.69 log CFU/g의 유의적인(p<0.05) 차이를 나타냈다. 병합 처리는 대조구와 비교하여 레드 치커리와 청경채의 저장 중 Hunter 색도 값에 부정적인 영향을 끼치지 않았다. 관능검사에 있어서도 병합 처리구가 대조구보다 저장 중 관능적 품질 유지에도 효과가 있는 것으로 나타났다. 따라서 본 연구결과, 50 ppm 이산화염소수와 10 kJ/$m^2$ UV-C 조사의 병합 처리가 레드 치커리와 청경채의 저장 중에 오염될 수 있는 위해미생물의 감소와 외관적 품질유지에 효과적인 처리 기술이라고 판단된다.

• 한국식품영양과학회지
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• 제41권11호
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• pp.1632-1638
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• 2012

치콘의 미생물학적 안전성을 확보하기 위해 50 ppm 이산화염소수와 5 kJ/$m^2$ UV-C 및 2 kGy 전자빔 조사 병합처리에 따른 저장 중 미생물 수 및 품질 변화를 $4{\pm}1^{\circ}C$에서 11일 동안 저장하면서 측정하였다. 이산화염소수와 UV-C 병합처리 후 치콘의 총 호기성 세균 수는 대조구와 비교하여 1.49~2.92 log CFU/g, 효모 및 곰팡이는 1.63~1.78 log CFU/g의 감소를 보였다. 반면에, 이산화염소수와 2 kGy 전자빔 병합처리구의 경우 총 호기성 세균은 저장기간 동안 검출되지 않았으며, 효모 및 곰팡이 역시 11일 간의 저장기간 동안 나타나지 않았다. 이산화염소수와 전자빔의 병합처리는 대조구와 비교하여 치콘의 저장 중 Hunter 색도 값에 부정적 영향을 미치지 않았다. 관능검사에 있어서도 저장기간 동안 대조구와 비교 시 유의적인 차이가 없는 것으로 나타났다. 따라서 본 연구결과, 이산화염소수와 전자빔 조사의 병합처리가 치콘의 저장 중 오염될 수 있는 위해미생물의 감소와 외관적 품질유지에 효과적인 살균처리 기술이라고 판단된다.

• 한국환경보건학회지
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• 제22권4호
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• pp.16-24
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• 1996

This study was performed to investigate the effect of co-existence of carbaryl and chlorothalonil on the short-term bioconcentration factor in Carassius auratus(goldfish). The fishes were exposed to the combined treatment of carbaryl and chlorothalonil(0.05 ppm+0.005 ppm, 0.05 ppm+0.010 ppm, 0.10 ppm+0.005 ppm) for 1, 3 and 5 days, respectively. Carbaryl and chlorothalonil in fish and in test water were extracted with n-hexane and acetonitrile. GC-ECD was used to detect and quantitate carbaryl and chlorothalonil. 1-day, 3-day and 5-day bioconcentration factors($BCF_1, BCF_3$ and $BCF_5$) of each pesticide were calculated from the quantitation results. The depuration rate of each pesticide from the whole body of fish was determined over the 72-h period after combined treatment. The results were as follows: $BCF_1$ values of carbaryl were 3.521, 3.802 and 3.587, respectively, when the concentration of carbaryl and chlorothalonil in combined treatment were 0.05+0.005, 0.05+0.010 and 0.10+0.005 ppm. BCF3 values of carbaryl were 4.825, 4.556 and 3.828, respectively, and $BCF_5$ values of carbaryl were 3.974, 3.921 and 4.186, respectively, under the conditions. While $BCF_1$ of chlorothalonil were 0.829, 0.829 and 1.540, respectively, under the same condition of pesticide concentrations $BCF_3$ of chlorothalonil were 2.040, 2.208 and 3.633, respectively, and $BCF_5$ of chlorothalonil were 6.222, 6.667 and 7.095, respectively, under the conditions. Depuration rate constants of carbaryl were 0.022, 0.022 and 0.152, respectively, when the concentration of carbaryl and chlorothalonil in combined treatment were 0.05+0.005, 0.05+0.010 and 0.10+0.005 ppm. While depuration rate constants of chlorothalonil were 0.004, 0.004 and 0.006, respectively, under the same condition of pesticide concentrations. It was observed that no significant differences of carbaryl and chlorothalonil concentration in fish extracts, test water and $BCF_s$ of carbaryl and chlorothalonil between combined treatment and single treatment. It was considered that no appreciable interaction at experimental concentrations was due to low concentrations, 0.005~0.1 ppm. Co-existence of carbaryl and chlorothalonil had no effect on excretion of each pesticide and depuration rate of chlorothalonil was investigated 1/8 slower than that of carbaryl in combined treatment. Therefore, it is considered that the persistence of chlorothalonil in fish body would be higher than that of carbaryl.

• Food Science and Biotechnology
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• 제15권4호
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• pp.529-533
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• 2006

To produce fresh-cut fruit products of high quality, the combined effects of postharvest calcium and heat treatment on Tsugaru apple were examined. Whole fruits were treated for 20 min at three different conditions: dipping in 3% $CaCl_2$ solution at $45^{\circ}C$ or ambient temperature, or in heated water at $45^{\circ}C$. The calcium content of the apples dipped in $CaCl_2$ solution at $45^{\circ}C$ was higher than that of the control and the non-heated calcium dipping. The fruits with calcium and heat treatment showed the same pattern of respiration rates as the control did during storage. The browning degree of the apple slices increased to approximately 3% after one-day storage, but no significant difference was observed between the treated and untreated apples. The fruits with $CaCl_2$ solution dipping at $45^{\circ}C$ had higher firmness than those with calcium dipping or heat treatment alone.

• 생물정신의학
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• 제5권2호
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• pp.155-161
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• 1998

Mood disorder is a medical illness resulting from the disorder of CNS neurotransmission and its principal therapeutic tool is pharmacotherapy. Psychotherapeutic drugs for mood disorder have some clinical limitations which are due to no or partial response, decreased compliance for drug by the side effects, and delayed therapeutic effects. So, general hope of all clinicians that mood diorder will respond to a single psychotherapeutic agent may be the exception rather than the rule. Recently, combined drug treatments have become increasingly popular to overcome the clinical limitations of individual agent in mood disorder. Combined treatments are usually used for augmenting or initiating rapidly the effect of drug, and for treating different target symptoms or drug side effects. When combined treatments being tried, knowledge of the action mechanism, pharmacokinetics, and pharmacodynamics is crucial to cope with the possible adverse reactions of drugs.

• Journal of Chest Surgery
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• 제24권1호
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• pp.41-47
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• 1991

From January, 1980, to August, 1989, 23 patients underwent thoracotomy for treatment of pulmonary aspergillosis on the Department of Thoracic and Cardiovascular Surgery, School of Medicine, Keimyung University. There were 12 male and 11 female patients ranging from 23 years to 61 years old[mean age, 40.7 years]. The main clinical symptoms were hemoptysis[91.3%], cough[65.2%], chest pain[34.5%]. Sixteen patients[69.6%] had simple aspergilloma and 7[30.4%] had complex aspergilloma. The most common indication for operation was a hemoptysis, indeterminate mass, chronic cough, or obstructed bronchus. Anatomical location of lesion was mainly located upper lobe [82.6%] and most of cases were managed by lobectomy. Postoperative pathologic findings showed that 13 case[56.5%] were combined with tuberculosis, two were combined with bronchiectasis and two were combined with lung tumor, but 6 cases were not combined with other disease. Early complications occurred in 33.5% of patients with simple aspergilloma and in 85.7% of patients with complex aspergilloma. But there was no hospital death.

• 생명과학회지
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• 제9권5호
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• pp.504-509
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• 1999

The trend of organogenesis in Xenopus presumptive ectoderm was studied by combined dose of activin A and IGF-1(insulin-like growth factor-1). In reference study of Asashima and his colleagues, the inductive patterns of various organs were reported with activin, the potent mesoderm inducing factor. In present study, the inducing pattern was cleared with combined-dose of concentration 1-100 ng/ml activin A and IGF-1. In addition, the result from single treatment of activin A was compared with former study. As a result, eye was differentiated in 5-20% of explants at 10 and 50 ng/ml concentrative combination of activin A. Otic vesicle was appeared in the entire concentrative combination of IGF-1. Pronephric duct was induced 19-38% of explants at the concentration of activin A 100 ng/ml by adding IGF-1. The comparison of single treatment of activin A was showed some difference in dose-dependent inducing pattern.