• Journal of the Korean Institute of Gas
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• v.1 no.1
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• pp.21-26
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• 1997

This paper presents the numerical results of six corrugation models which compute the stress behaviours and stress levels of the membrane structure under the hydrostatic pressure of cryogenic liquids and thermal loadings using a non -linear finite element analysis program. A three-dimensional analysis of various corrugation geometries was performed on the maximum mean normal stress distributions along the upper surface of the membrane sheet. Comparisons of the FEM results for various geometry models of the corrugation are presented, which shows that the corrugated configuration of the ring knot model can be effectively performed for the combined forces such as the hydrostatic pressure and thermal loading in comparison with the Technigaz type corrugation which has small comer and apex curvatures. The FEM results show that the ring knot corrugation can be used for the deepest depth, 180m of the LNG storage tank in comparison with other corrugation models.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.40 no.2
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• pp.167-173
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• 2016

This paper proposes ductile failure simulation under high strain rate conditions using finite element (FE) analyses. In order to simulate a cracked component under a high strain rate condition, this paper applies the stress-modified fracture strain model combined with the Johnson/Cook model. The stress-modified fracture strain model determines the incremental damage in terms of stress triaxiality (${\sigma}_m/{\sigma}_e$) and fracture strain (${\varepsilon}_f$) for a dimple fracture using the tensile test results. To validate the stress-modified fracture strain model under dynamic loading conditions, the parameters are calibrated using the tensile test results under various strain rates and the fracture toughness test results under quasi-static conditions. The calibrated damage model predicts the CT test results under a high strain rate. The simulated results were then compared with the experimental data.

• Journal of Microbiology and Biotechnology
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• v.26 no.10
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• pp.1746-1754
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• 2016

Recently, spherical beads entrapping quorum quenching (QQ) bacteria have been reported as effective moving QQ-media for biofouling control in MBRs for wastewater treatment owing to their combined effects of biological (i.e., quorum quenching) and physical washing. Taking into account both the mass transfer of signal molecules through the QQ-medium and collision efficiencies of the QQ-medium against the filtration membranes in a bioreactor, a cylindrical medium (QQ-cylinder) was developed as a new shape of moving QQ-medium. The QQ-cylinders were compared with previous QQ-beads in terms of the QQ activity and the physical washing effect under identical loading volumes of each medium in batch tests. It was found that the QQ activity of a QQ-medium was highly dependent on its specific surface area, regardless of the shape of the medium. In contrast, the physical washing effect of a QQ-medium was greatly affected by its geometric structure. The enhanced anti-biofouling property of the QQ-cylinders relative to QQ-beads was confirmed in a continuous laboratory-scale MBR with a flat-sheet membrane module.

• Steel and Composite Structures
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• v.29 no.1
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• pp.77-90
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• 2018

This paper presents a combined numerical, experimental, and theoretical study on the behavior of the concrete-filled double circular steel tubular (CFDT) stub columns under axial compressive loading. Four groups of stub column specimens were tested in this study to find out the effects of the concrete strength, steel ratio and diameter ratio on the mechanical behavior of CFDT stub columns. Nonlinear finite element (FE) models were also established to study the stresses of different components in the CFDT stub columns. The change of axial and transverse stresses in the internal and external steel tubes, as well as the change of axial stress in the concrete sandwich and concrete core, respectively, was thoroughly investigated for different CFDT stub columns with the same steel ratio. The influence of inner-to-outer diameter ratio and steel ratio on the ultimate bearing capacity of CFDT stub columns was identified, and a reasonable section configuration with proper inner-to-outer diameter ratio and steel ratio was proposed. Furthermore, a practical formula for predicting the ultimate bearing capacity was proposed based on the ultimate equilibrium principle. The predicted results showed satisfactory agreement with both experimental and numerical results, indicating that the proposed formula is applicable for design purposes.

• Archives of Pharmacal Research
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• v.20 no.4
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• pp.297-305
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• 1997

A new serum-free defined medium was developed that supports the growth of normal rat mammary epithelial cells. Mammary organoids from the glands of female F344 rats were cultured in a serum-free medium. Monolayer culture colonies developed within a week and remained viable for months in culture. Upon subculture of one-week-old primary colonies, almost the same morphology of colonies was developed. The scrape loading/dye transfer technique showed that most of colonies that developed in a serum-free medium containing EGF, human transferrin, insulin, and hydrocortisone (basal serum-free medium, BSFM) failed to show cell-cell communication. However, colonies cultured in BSFM supplemented with prolactin, $E_2$, and progesterone (complete hormone serum-free medium, CHSFM) showed cell-cell communication at 14 days of primary culture or of subculture. By flow cytometry with FITCPNA and PE-anti-Thy-1.1 monoclonal antibody, we distinguished four RMEC subpopulations in cultures in both media: Thy-1.1+ cells, PNA+ cells, cells negative to both reagents and cells positive to both reagents. It is likely that combined prolactin, cortisol, and insulin in CHSFM stimulate terminal differentiation of clonogenic cells.

• Proceedings of the KSRS Conference
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• v.1
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• pp.236-238
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• 2006

An algorithm for detection of yellow sand aerosols has been developed with infrared bands from Moderate Resolution Imaging Spectroradiometer (MODIS) and Multi-functional Transport Satellite-1 Replacement (MTSAT-1R) data. The algorithm is the hybrid algorithm that has used two methods combined together. The first method used the differential absorption in brightness temperature difference between $11{\mu}m$ and $12{\mu}m$ (BTD1). The radiation at 11 ${\mu}m$ is absorbed more than at 12 ${\mu}m$ when yellow sand is loaded in the atmosphere, whereas it will be the other way around when cloud is present. The second method uses the brightness temperature difference between $3.7{\mu}m$ and $11{\mu}m$ (BTD2). The technique would be most sensitive to dust loading during the day when the BTD2 is enhanced by reflection of $3.7{\mu}m$ solar radiation. We have applied the three methods to MTSAT-1R for derivation of the yellow sand dust and in conjunction with the Principle Component Analysis (PCA), a form of eigenvector statistical analysis. As produced Principle Component Image (PCI) through the PCA is the correlation between BTD1 and BTD2, errors of about 10% that have a low correlation are eliminated for aerosol detection. For the region of aerosol detection, aerosol index (AI) is produced to the scale of BTD1 and BTD2 values over land and ocean respectively. AI shows better results for yellow sand detection in comparison with the results from individual method. The comparison between AI and OMI aerosol index (AI) shows remarkable good correlations during daytime and relatively good correlations over the land.

• Journal of Korean Society on Water Environment
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• v.21 no.5
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• pp.458-463
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• 2005

Considering the characteristics of a filtration bio-reactor equipped with a mesh filter module which can effectively maintain high concentration of biomass and enhanced solid-liquid separation performance, the hybrid process of filtration bio-reactor combined with coagulation was investigated to get improved filtration characteristics as well as water quality in this work. Two bio-reactors (Run-1 & Run-2) were operated under the following conditions: working volume of 25 L, continuous loading of a synthetic wastewater (BOD: 200 mg/L, T-N: 50 mg/L, T-P: 5 mg/L), where an appropriate amount of alum ($Al_2(SO_4)_3{\cdot}18H_2O$) was added once a day into the reactor (Run-2). In the system without using a alum (Run-1), the clogging of mesh filter module was observed two times through 85 days of whole operation. Meanwhile, the filter module did not clog even at higher MLSS concentration (6,000~12,000 mg/L) and the stable filtration (0.7 mid) was continued in the case of using a alum. Due to the stable formation of cake layers, BOD and SS were shown below 6 and 3 mg/L, respectively. T-P and pH of the effluent were changed because of the intermittent addition of the alum. In the case of Al/P=2.5, the average T-P removal efficiency per day was 85.2% and the average T-P concentration of the effluent was 0.3 mg/L. However, the removal efficiency of phosphate was influenced by pH in the reactor.

• Bulletin of the Korean Chemical Society
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• v.35 no.6
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• pp.1720-1726
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• 2014

(S)-Alanine Racemase Chiral Analogue ((S)-ARCA) was used as an efficient adsorbent for the selective separation of D-amino acids (D-AAs), which are industrially important as chiral building blocks for the synthesis of pharmaceutical intermediates. The organic phase, containing (S)-ARCA adsorbent and phase transfer reagents, such as ionic liquid type molecules (Tetraphenylphosphonium chloride (TPPC), Octyltriphenylphosponium bromide (OTPPBr)), were coated on the surfaces of mesoporous carbon supports. For the immobilization of chiral adsorbents, meso/macroporous monolithic carbon (MMC), having bimodal pore structures with high surface areas and pore volumes, were fabricated. The separation of chiral AAs by adsorption onto the heterogeneous (S)-ARCA was performed using a continuous flow type packed bed reactor system. The effects of loading amount of ARCA on the support, the molar ratio of AA to ARCA, flow rates, and the type of phase transfer reagent (PTR) on the isolation yields and the optical purity of product D-AAs were investigated. D-AAs were selectively combined to (S)-ARCA through imine formation reaction in an aqueous basic solution of racemic D/L-AA. The (S)-ARCA coated MMC support showed a high selectivity, up to 95 ee%, for the separation of D-type phenylalanine, serine and tryptophan from racemic mixtures. The ionic liquids TPPC and OTPPBr exhibited superior properties to those of the ionic surfactant Cetyltrimethyl ammonium bromide (CTAB), as a PTR, showing constant optical purities of 95 ee%, with high isolation yields for five repeated reuses. The unique separation properties in this heterogeneous adsorption system should provide for an expansion of the applications of porous materials for commercial processes.

• Journal of Dental Anesthesia and Pain Medicine
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• v.18 no.5
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• pp.295-300
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• 2018

Background: Removal of the plate following Le Fort I osteotomy and BSSO (bilateral sagittal split osteotomy) is a common procedure. However, patients who undergo plate removal experience intense pain and discomfort. This study investigated the half-maximal effective concentration ($Ce_{50}$) of remifentanil in the prevention of plate removal pain under sedation using dexmedetomidine. Methods: The study evaluated 18 patients, between 18 and 35 years of age, scheduled for elective surgery. Remifentanil infusion was initiated after sedation using dexmedetomidine, and started at a dose of 1.5 ng/mL on the first patient via target-controlled infusion (TCI). Patients received a loading dose of $1.0{\mu}g/kg$ dexmedetomidine over 10 min, followed by a maintenance dose of $0.7{\mu}g/kg/h$. When the surgeon removed the plate, the patient Modified Observer's Assessment of Alertness/Sedation (MOAA/S) score was observed. Results: The Ce of remifentanil ranged from 0.9 to 2.1 ng/mL for the patients evaluated. The estimated effect-site concentrations of remifentanil associated with a 50% and 95% probability of reaching MOAA/S score of 3 were 1.28 and 2.51 ng/mL, respectively. Conclusion: Plate removal of maxilla can be successfully performed without any pain or adverse effects by using the optimal remifentanil effect-site concentration ($Ce_{50}$, 1.28 ng/mL; $Ce_{95}$, 2.51 ng/mL) combined with sedation using dexmedetomidine.

• The Journal of Advanced Prosthodontics
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• v.10 no.4
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• pp.300-307
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• 2018

PURPOSE. To investigate the fatigue and fracture resistance of computer-aided design and computer-aided manufacturing (CAD/CAM) ceramic molar crowns on dental implants and human teeth. MATERIALS AND METHODS. Molar crowns (n=48; n=8/group) were fabricated of a lithium-disilicate-strengthened lithium aluminosilicate glass ceramic (N). Surfaces were polished (P) or glazed (G). Crowns were tested on human teeth (T) and implant-abutment analogues (I) simulating a chairside (C, crown bonded to abutment) or labside (L, screw channel) procedure for implant groups. Polished/glazed lithium disilicate (E) crowns (n=16) served as reference. Combined thermal cycling and mechanical loading (TC: $3000{\times}5^{\circ}C/3000{\times}55^{\circ}C$; ML: $1.2{\time}10^6$ cycles, 50 N) with antagonistic human molars (groups T) and steatite spheres (groups I) was performed under a chewing simulator. TCML crowns were then analyzed for failures (optical microscopy, SEM) and fracture force was determined. Data were statistically analyzed (Kolmogorow-Smirnov, one-way-ANOVA, post-hoc Bonferroni, ${\alpha}=.05$). RESULTS. All crowns survived TCML and showed small traces of wear. In human teeth groups, fracture forces of N crowns varied between $1214{\pm}293N$ (NPT) and $1324{\pm}498N$ (NGT), differing significantly ($P{\leq}.003$) from the polished reference EPT ($2044{\pm}302N$). Fracture forces in implant groups varied between $934{\pm}154N$ (NGI_L) and $1782{\pm}153N$ (NPI_C), providing higher values for the respective chairside crowns. Differences between polishing and glazing were not significant ($P{\geq}.066$) between crowns of identical materials and abutment support. CONCLUSION. Fracture resistance was influenced by the ceramic material, and partly by the tooth or implant situation and the clinical procedure (chairside/labside). Type of surface finish (polishing/glazing) had no significant influence. Clinical survival of the new glass ceramic may be comparable to lithium disilicate.