• Journal of Korean Neurosurgical Society
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• v.46 no.4
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• pp.351-354
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• 2009

Objective : Combined hyperative dysfunction syndrome (HDS) defined as the combination of HDSs such as trigeminal neuralgia (TN). hemifacial spasm (HFS) and glossopharyngeal neuralgia (GPN), which mayor may not occur simultaneously on one or both sides. We reviewed patients with combined HDS and demonstrated their demographic characteristics by comparing them with those of patients with a single HDS. Methods : Between October 1994 and February 2006, we retrospectively studied a series of 1,720 patients who suffered from HDS and found 51 patients with combined HDSs. We analyzed several independent variables in order to evaluate the prevalence and etiologic factors of combined HDS. Results : The combined HDS group accounted for 51 of 1,720 (2.97%) patients with HDS; 27 cases of bilateral HFS, 10 cases of bilateral TN and 14 cases of HFS with TN. Their mean age was 52.1 years (range, 26-79 years). There were 5 men and 46 women. Seven patients had synchronous and 44 patients metachronous onset of HDSs. By comparison of combined and single HDS groups, we found that age and hypertension were closely associated with the prevalence of combined HDS (p<0.05). Conclusion : This study revealed that combined HDS was very rare. Hypertension and age might be the most important causative factors to evoke combined HDS.

• Journal of Gastric Cancer
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• v.10 no.3
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• pp.118-125
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• 2010

Purpose: Operative morbidity and mortality from gastric cancer have decreased in recent years, but many studies have demonstrated that its prevalence is still high. Therefore, we investigated the risk factors for morbidity and mortality considering the type of complication in patients with gastric cancer. Materials and Methods: A total of 259 gastrectomies between 2004 and 2008 were retrospectively reviewed. Results: Overall morbidity and mortality rates were 26.6% and 1.9%, respectively. A major risk factor for morbidity was combined resection (especially more than two organs) (P=0.005). The risk factors for major complications in which a re-operation or intervention were required were type of gastrectomy, upper location of lesion, combined resection, and respiratory comorbidity (P=0.042, P=0.002, P=0.031). Mortality was associated with preexisting neurologic disease such as cerebral stroke (P=0.016). In the analysis of differen complication's risk factors, a wound complication was not associated with any risk factor, but combined resection was associated with bleeding (P=0.007). Combined resection was an independent risk factor for a major complication, surgical complication, and anastomotic leakage (P=0.01, P=0.003, P=0.011, respectively). Palliative resection was an independent risk factor for major complications and a previous surgery for malignant disease was significantly related to anastomosis site leakage (P=0.033, P=0.007, respectively). Conclusions: The risk factors for gastrectomy complications of gastric cancer were combined resection, palliative resection, and a previous surgery for a malignant disease. To decrease post-gastrectomy complications, we should make an effort to minimize the range of combined resection, if a palliative gastrectomy is needed for advanced gastric cancer.

• Proceedings of the Korea Concrete Institute Conference
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• 2005.11a
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• pp.407-410
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• 2005

This research investigates experimentally an effect on the properties of the combined high flowing concrete by mix design factors. The purpose of this study is to determine the optimum mix proportion of the combined high flowing concrete having good flowability, viscosity, no-segregation and design strength(40.0MPa). For this purpose, trial mixings used belite cement+lime stone powder(LSP) are tested by mix design factors including water-cement ratio($47.9\~54.0\%$), fine aggregate volume ratio($41\~45\%$) and coarse aggregate volume ratio($41\~45\%$). As test results of this study, the optimum mix proportion for the combined high flowing concrete is as followings. Water-cement ratio $51.0\%$, fine aggregate volume ratio $43{\pm}1\%$ and coarse aggregate volume ratio $0.30{\pm}0.05m^3/m^3$ and replacement ratio of LSP $42.7\%$.

• Journal of the Korean Society of Safety
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• v.13 no.3
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• pp.24-31
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• 1998

Variable thickness plates are commonly encountered in the majority of mechanical/structural components of industrial applications. And, as a result of the unsymmetry of the structure or the load and the anisoptropy of the materials, the cracks in engineering structures are generally subjected to combined stresses. In spite of considerable practical interest, however, a few fracture mechanics study on combined mode crack in a variable thickness plate have carried out. In this respect, combined mode I/III stress intensity factors $K_I$ and $K_III$ at the crack tip for a variable thickness plate were obtained by 3-dimensional finite element analysis. Variable thickness plates containing a central slant crack were chosen. The parameters used in this study were dimensionless crack length $\lamda$, crack slant angle $\alpha$, thickness ratio $\beta$ and width ratio $\omega$. Stress intensity factors were calculated by crack opening displacement(COD) and crack tearing displacement(CTD) method.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.7
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• pp.1416-1425
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• 2002

In this study, the effects of combined environmental factors on mechanical and thermal analysis properties of graphite/epoxy composites were evaluated by the use of an accelerated aging test. Environmental factors such as temperature, moisture. and ultraviolet were considered. A xenon-arc lamp was utilized for ultraviolet light. and exposure times of up to 3000 hours were applied. Several types of specimens - tensile. bending, and shear specimens those are transverse to the fiber direction, and bending specimens those are parallel to the tiber direction - were used to investigate the effects of environmental factors on mechanical properties of the composites. Also, glass transition temperature, storage shear modulus, loss shear modulus, and tan ${\delta}$ were measured as a function of exposure times through a dynamic mechanical analyzer. In addition. a suitable testing method for determining the effect of environmental factors on mechanical properties is suggested by comparing the results from using two different types of strain measuring sensors. Finally, composite surfaces exposed to environmental factors were examined using a scanning electron microscope.

• Journal of Korean Biological Nursing Science
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• v.16 no.2
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• pp.105-112
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• 2014

Purpose: The purpose of this study was to examine the effects of a Combined Exercise Program on Obesity and Metabolic Syndrome Factors for Chronic Psychiatric Inpatients. Methods: Thirty two subjects participated in this program who were admitted into a national mental hospital of C city. All measurements were done at baseline, 4 week, 8 week, and 12 week during the program. The effectiveness of the program was evaluated according to the change of body mass index, body fat, waist circumference, total cholesterol, high density lipoprotein cholesterol, triglyceride, and fasting blood sugar. Collected data was analyzed by frequency, percentage, and repeated measures ANOVA with SPSS WIN 19.0. Results: There were statistically significant differences in the body mass index (p=.002), body fat (p<.001), waist circumference (p<.001), triglyceride (p=.020), and fasting blood sugar (p=.008). However, there were no statistically significant differences in the total cholesterol, or high density lipoprotein cholesterol. Conclusion: The results of this study showed that a combined exercise program has positive effect on obesity and metabolic syndrome factor. Thus, a Combined Exercise program is recommended as an intervention to improve obesity and metabolic syndrome factors for chronic psychiatric inpatients.

• Journal of International Academy of Physical Therapy Research
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• v.2 no.2
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• pp.329-338
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• 2011

The purpose of this study is to examine the effect of stabilization, resistance exercise, and combined exercise for lumbar on balance and walking ability of elderly. This study selected 22 subjects of over 65 years old elderly women who satisfy the study condition from A, B and C Senior Citizen's Center, in Daegu. The subjects were divided into groups; 7 for resistance exercise group, 8 for stabilization exercise group, and 7 for combined exercise group(resistance and stabilization exercise). The exercises were conducted for 60min a day, three times a week for 12 weeks. Balance and walking ability were checked before the exercise, 6 weeks later, and 12 weeks later. First, all lumbar muscle strengthening exercises were effective for static balance which changed according to exercising period. In dynamic balance, the resistance exercise group showed significant improvement in sit to stand. Stabilization exercise group showed significant improvement in all factors. The combined exercise group showed significant improvement in sit to stand and timed up and go. There was no difference between the exercise types. Second, the resistance exercise group showed significant change in Cadence which changed according to exercising period. The combined exercise group showed significant improvement in all factors. Between the exercise types, combined exercise was a bit more effective than resistance exercise. According to the result of 12 weeks of lumbar muscle exercise, combined exercise is considered to be the most effective exercise to prevent fall as it helps balance and walking ability slightly more than other exercises. Therefore, this study can understand the risk factors for fall accidents that frequently occur among elderly and adopt the combined exercise to prevent fall which in turn will prevent secondary problems occur from fall accidents and improve quality of life of elderly.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5941-5944
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• 2014

Purpose: To highlight the potential factors that could predict the response rate of patients with metastatic colorectal cancer (mCRC) treated with pemetrexed combined chemotherapy after first- or second-line chemotherapy using the FOLFOX regimen. Materials and Methods: Between January 2007 and July 2014, 54 patients diagnosed and pathologically-confirmed with advanced colorectal cancer in Jiangsu Cancer Hospital and Research Institute, were enrolled. They received pemetrexed at a dose of $500mg/m^2$ by 10 minute infusion on day 1, repeated every 3 weeks. Doses were modified depending on nadir counts of blood cells. Combined chemotherapeutic agents included irinotecan, lobaplatin, carboplatin, oxaliplatin, gemcitabine, cis-platinum or bevacizumab. Multiple variables (age, sex, hemoglobin, platinum drugs combined, metastasis sites, LDH, ALP, CEA>40 ug/ml) reported earlier were selected. We used logistic regression analysis to evaluate relationships between these and tumor response. Results: On multivariable analysis, we found that age was significant in predicting the responsiveness to pemetrexed (p<0.05) combined with oxaliplatin. We did not find any other factors which were significantly associated with the response rate to chemotherapy with pemetrexed and irinotecan. Conclusions: By multivariate analysis, we found that age had significant impact on the responsiveness of pemetrexed when combined with oxaliplatin. Additional research based on genomic properties of host and tumors are needed to clarify markers for better selection of patients who could benefit from pemetrexed combined chemotherapy.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.8
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• pp.1875-1882
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• 1993

Variable thickness plates are commonly used as structural members in the majority of industrial sectors. Previous fracture mechanics researches on variable thickness plates were limited to mode I loading cases. In practice, however, cracks are usually located inclined to the loading direction. In this respect, combined mode(mode I/II) stress intensity factors $K_{I}$ and $K_{II}$ at the crack tip for a variable thickness plate were obtained by 3-dimensional finite element analysis. Variable thickness plates containing a slant edge crack were chosen. The parameters used in this study were dimensionless crack $length{\lambda}$, slant $angle{\alpha}$, thickness $ratio{\beta}$ and width ratio{\omega}$. Stress intensity factors were calculated by crack opening displacement(COD) and crack sliding displacement(CSD)method proposed by Ingraffea and Manu.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.183-188
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• 2007

In this paper, we propose a 2D-FE model in single impact with combined physical factors to obtain a unique residual stress by shot peening. Applied physical parameters include elastic-plastic deformation of shot ball, material damping coefficients, strain rate, dynamic friction coefficients. Single impact FE model consists of 2D axisymmetric elements. The FE model with combined factors showed converged and unique distributions of surface stress, maximum compressive residual stress and deformation depth. Further, in contrast to the FE models with rigid shot and elastic deformable shot, FE model with plastic deformable shot produces residual stresses very close to experimental solutions by X-ray diffraction. We therefore validated the 2D FE model with combined peeing factors and plastic deformable shot. This FE model will be a base of the 3D FE model for residual stresses by multi-impact shot peening.