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Lesion Localization in Patients with Hyperparathyroidism Using Double-phase Tc-99m MIBI Parathyroid Scintigraphy (부갑상선기능항진증 환자에서 Tc-99m MIBI 부갑상선 신티그라피를 이용한 병소 국소화)

  • Shin, Jung-Woo;Ryu, Jin-Sook;Kim, Jae-Seung;Moon, Dae-Hyuk;Hong, Seung-Mo;Gong, Gyung-Yub;Hong, Suk-Joon;Lee, Hee-Kyung
    • The Korean Journal of Nuclear Medicine
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    • v.33 no.2
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    • pp.120-130
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    • 1999
  • Purpose: This study was performed to evaluate the diagnostic usefulness of double-phase Tc-99m MIBI parathyroid scintigraphy with single photon emission computed tomography (SPECT) in patients with hyper-parathyroidism. We also evaluated the relationship between Tc-99m MIBI uptake and oxyphil cell contents in parathyroid glands. Materials and Methods: The subjects were 28 parathyroid glands of 10 patients who underwent Tc-99m MIBI parathyroid scintigraphy and parathyroidectomy for clinically suspected hyper-parathyroidism. Early and delayed pinhole images were obtained at 15 minutes and 2 hours after injection of Tc-99m MIBI, and SPECT images were followed. The weight and oxyphil cell contents of parathyroid tissue were obtained from pathologic specimen, and the scintigraphic findings were compared with histopathology. Results: In surgical histopathology, 6 parathyroid adenomas and 9 parathyroid hyperplasias were confirmed. The sensitivity, specificity, and positive predictive value of early and delayed images were 46.7% (7/15), 76.9% (10/13), 70% (7/10) and 66.7% (10/15), 92.3% (12/13), 90.9% (10/11), respectively. SPECT image detected an additional small hyperplasia.. The sensitivity, specificity, and positive predictive value of combined interpretation of early and delayed images with SPECT were 73.3% (11/15), 100% (13/13), 100% (11/11). The sensitivity was 100% (6/6) for adenoma, whereas that was 55.5% (5/9) for hyperplasia. Both adenomas and hyperplasias showed significantly increased oxyphil cell contents compared with normal parathyroid glands (p<0.0001), but the oxyphil cell content and weight were not significantly different between adenomas and hyperplasias. Conclusion: Double-phase Tc-99m MIBI parathyroid scintigraphy with SPECT is useful for lesion localization in patients with hyperparathyroidism. Although both adenoma and hyperplasia have increased oxyphil cell content, the sensitivity is high in adenoma, but low in hyperplasia.

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Study on the Interpretation of the Features Affacting to the N-supplying Capability of Field Soils to Corn in Pennsylvania (Pennsylvania주 옥수수재배지(栽培地) 토양(土壤)의 질소공급능력(窒素供給能力)에 영향(影響)을 미치는 요인분석(要因分析))

  • Hong, Soon-Dal
    • Korean Journal of Soil Science and Fertilizer
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    • v.25 no.1
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    • pp.26-37
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    • 1992
  • Fifty-five field experiments were conducted in order to find out some useful indices for the prediction of N-supplying capability(NSC) of soils under cultivation of corn in Pennsylvania over 3 years from 1986. Contents of $NO_3-N$, absorbance at 200 nm of the extract from soil with 0.01M $NaHCO_3$ were identified to be used as indices before planting. Methods for the estimation of organic nitrogen available later in the growing season(KCLA-N, PBBA-N, UV260 nm absorbance of $NaHCO_3$ extract) were not to be used as good indices individually, but when those are combined together with inorganic $NO_3-N$ showed a highly significant correlationship with the NSC. The year of an even distribution of rainfall, 1987, gave the highest significant correlationship between NSC and the indices. For soils of the same texture with slightly different physical properties, combined indices obtained from physico-chemical factors improved the degree of predictability when the grades of soil slope, depth of Ap were considered at the same time. More futher researches such as this need to be done before any conclusive result can be drawn.

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Protective Effects of Lotus Root (Nelumbo nucifera G.) Extract on Hepatic Injury Induced by Alcohol in Rats (알코올로 유발된 흰쥐의 간손상에 대한 연근 추출물의 간 보호효과)

  • Lee, Jae-Joon;Park, Se-Young;Lee, Yu-Mi;Lee, Myung-Yul
    • Food Science and Preservation
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    • v.13 no.6
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    • pp.774-782
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    • 2006
  • This study investigated the hepatoprotective effects of an ethanol extract of lotus root (LRE) on alcohol-induced liver damage in rat. Sprague-Dawley rae weighing $100{\sim}150g$, were divided into 6 groups: basal diet group (BD), alcohol (35% 10 mL/kg/day) teated stoup (ET), LRE 200 mg/kg/day teated group (BD-LREL). LRE 400 mg/kg/day treated group (BD-LREH), LRE 200 mg/kg/day and alcohol treated group (ET-LREL), and LRE 400 3mg/kg/day and alcohol teated group (ET-LREH). After the administration, rats were sacrificed to get serum and liver to analyze antioxidant enzyme activity, glutathione and lipid peroxide contents. The body weight gain and feed efficiency ratio were decreased by alcohol administration, however, were gradually increased to a little lower level than the basal diet group by the combined administration of alcohol and LRE. The serum alanine aminotransferase (ALT), asparate aminotransferase (AST) and alkaline phosphatase (ALP) activities that were elevated by alcohol were significantly decreased by LRE administration. It was also observed that thiobarbituric acid reactive substances (TBARS) content, xanthine oxidase (XO), superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-Px) activities in liver that were increased by alcohol, were markedly decreased in the combined alcohol and LRE administered groups as compared with the alcohol administrated group. These effect of LRE within the alcohol groups were in a dose-dependent manner. The glutathione (GSH) content in liver was decreased by alcohol administration, however, increased after administering LRE. Teken together, these result suggest that ethanol extract of lotus root may have a possible protective effect on liver function in hepatotoxicity-induced rat by alcohol administration.

Batch Scale Storage of Sprouting Foods by Irradiation Combined with Natural Low Temperature - I. Storage of Potatoes - (방사선(放射線) 조사(照射)와 자연저온(自然低溫)에 의한 발아식품(發芽食品)의 Batch Scale 저장(貯藏)에 관(關)한 연구(硏究) - 제(第) 1 보(報) : 감자의 저장(貯藏) -)

  • Cho, Han-Ok;Byun, Myung-Woo;Kwon, Joong-Ho;Yang, Ho-Sook;Lee, Chul-Ho
    • Korean Journal of Food Science and Technology
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    • v.14 no.4
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    • pp.355-363
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    • 1982
  • In order to develop the commercial storage method of potatoes by irradiation combined with natural low temperature, storage room($450{\times}650{\times}250cm$; year round temperature change, $2-17^{\circ}C;\;70-85%\;R.H.$) on a batch scale followed by irradiation with optimum dose level. Irish cobbler and Shimabara were 100% sprouted after 3 months storage in control, whereas in 15 Krad irradiated group, sprouting was completely inhibited at Irish cobbler for 9 months storage, and at Shimabara for 12 months. The extent of loss due to rot attack after 9 months storage was 6% in control, 6-8% in 10-15 Krad irradiated group at Irish cobbler and weight loss was 16.5% in control, 5.1-5.6% in irradiated group, whereas rotting rate of Shimabara after 12 months storage was 100% in control, 15% in irradiated group and the weight loss of its was 12.6% in control, $7.3{\sim}7.4%$ in irradiated group. The moisture content in whole storage period of two varieties were $72{\sim}82%$ without remarkable changes. The total sugar and ascorbic acid contents were slightly decreased according to the dose increase and elapse of storage period, whereas reducing sugar content was increased. Irish cobbler was 90% marketable after 9 months storage and 85% in Shimabara after 12 months storage.

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Pseudo Image Composition and Sensor Models Analysis of SPOT Satellite Imagery for Inaccessible Area (비접근 지역에 대한 SPOT 위성영상의 Pseudo영상 구성 및 센서모델 분석)

  • 방기인;조우석
    • Korean Journal of Remote Sensing
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    • v.17 no.1
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    • pp.33-44
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    • 2001
  • The paper presents several satellite models and satellite image decomposition methods for inaccessible area where ground control points can hardly acquired in conventional ways. First, 10 different satellite sensor models, which were extended from collinearity condition equations, were developed and then behavior of each sensor model was investigated. Secondly, satellite images were decomposed and also pseudo images were generated. The satellite sensor model extended from collinearity equations was represented by the six exterior orientation parameters in $1^{st}$, $2^{nd}$ and $3^{rd}$ order function of satellite image row. Among them, the rotational angle parameters such as $\omega$(omega) and $\Phi$(phi) correlated highly with positional parameters could be assigned to constant values. For inaccessible area, satellite images were decomposed, which means that two consecutive images were combined as one image, The combined image consists of one satellite image with ground control points and the other without ground control points. In addition, a pseudo image which is an imaginary image, was prepared from one satellite image with ground control points and the other without ground control points. In other words, the pseudo image is an arbitrary image bridging two consecutive images. For the experiments, SPOT satellite images exposed to the similar area in different pass were used. Conclusively, it was found that 10 different satellite sensor models and 5 different decomposed methods delivered different levels of accuracy. Among them, the satellite camera model with 1st order function of image row for positional orientation parameters and rotational angle parameter of kappa, and constant rotational angle parameter omega and phi provided the best 60m maximum error at check point with pseudo images arrangement.

Quality Characteristics of Doenjang Meju Fermented with Aspergillus Species and Bacillus subtilis during Fermentation (Aspergillus속과 Bacillus subtilis를 이용한 된장메주 발효 중 품질 특성)

  • Kim, Jong-Wook;Doo, Hong-Soo;Kwon, Tae-Ho;Kim, Yong-Suk;Shin, Dong-Hwa
    • Food Science and Preservation
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    • v.18 no.3
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    • pp.397-406
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    • 2011
  • To industrialize meju, four kinds of meju (Korean-style soybean koji) were made with humidity-controlled fermentation for 12 days at $28^{\circ}C$ after they were inoculated with selected strains such as Aspergillus otyzae (AO meju), Aspergillus sojae (AS meju), combined Aspergillus sojae and Bacillus subtilis (ASBS meju), and combined Aspergillus oryzae and Bacillus subtilis (AOBS meju) as starter microorganisms. The changes in the quality characteristics in the four kinds of meju were investigated during fermentation. Their enzyme activities were compared with those of the traditional meju that is made in Sunchang Folk Village according to the traditional method. In the meju that were inoculated with selective strains, the aerobic bacteria counts and mold counts exceeded 8 log cfu/g and 6 log cfu/g respectively, which were the highest fermentation values after 2 days. The aerobic bacteria counts were maintained from 2-day to the 12-day fermentation. The mold counts tended to decreased gradually after the 2-day fermentation. The amino-type nitrogen contents reached 430.5-577.5 mg%, which were the highest values after 2-day fermentation. The neutral protease activities of these mejus had the highest levels in the following order: traditional meju, $1,258.0{\pm}38.8$; AS meju, $1,238.3{\pm}38.6$; AO meju. $1,204.1{\pm}24.1$; ASBS meju, $1,040.6{\pm}10.6$; and AOBS meju, $1,033.5{\pm}11.2$ unit/g. The acidic protease activities of these meju had the highest levels in the following order: AO meju, $1,030.1{\pm}19.1$, traditional meju, $1,007.7{\pm}30.5$; AS meju, $990.9{\pm}25.0$; AOBS meju, $910.9{\pm}15.3$; and ASBS meju, $888.2{\pm}15.7$ unit/g.

Effect of Combined Supplementation Catechin and Vitamin C on Growth Performance, Meat Quality, Blood Composition and Stress Responses of Broilers under High Temperature (고온 환경에서 카테킨 및 비타민 C 첨가가 육계의 생산성, 계육품질, 혈액성분 및 스트레스 지표에 미치는 영향)

  • Jiseon Son;Woo-Do Lee;Hee-jin Kim;Hyunsoo Kim;Eui-Chul Hong;Iksoo Jeon;Hwan-Ku Kang
    • Korean Journal of Poultry Science
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    • v.50 no.1
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    • pp.1-13
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    • 2023
  • The study was carried out to investigate the effects of dietary combined supplementation of antioxidants as catechin and vitamin C on growth performance, meat quality, blood profiles and stress responses of broilers exposed to high temperature. For this experiment, a total of 360 21-day-old male Ross 308 broilers were used. Treatments were assigned with 6 replicates per treatment and 10 birds per replicate in a 2 × 3 factorial design with vitamin C (0, 250 mg/kg) and catechin (0, 600, 1,200 mg/kg). The heat stress environment was maintained at temperature 32±1℃ and relative humidity 60±5% for 24 hours until the end of the experiment. The supplemented antioxidants had no significant difference in weight gain, feed intake and feed conversion ratio (P>0.05). The content of total cholesterol in blood had no interaction, but decrease (P<0.01) in the supplemented catechin group. Also, the supplementation with catechin showed increase in the SOD activity of blood, and lower corticosterone and IgM levels of broilers. The contents of HSP70 and MDA in liver decrease (P<0.05) with the supplementation of antioxidants, and HSP70 showed an interaction between groups. DPPH radical scavenging ability in breast meat increased (P<0.01) in catechin, but meat quality did not show difference according to treatments. Respiratory rate decreased (P<0.05) in catechin, but no interaction with vitamin C. In conclusion, the combination of vitamin C and catechin can alleviate stress under high temperature, such as HSP70 and MDA, but further study on the optimal supplemental level is needed.

A Study on the Kyungsangnamdo Native Local Food Culture in the Novel "Toji" (소설 "토지"에 나타난 경상남도 향토 음식문화)

  • Kim, Mi-Hye;Chung, Hae-Kyung
    • Journal of the Korean Society of Food Culture
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    • v.26 no.6
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    • pp.583-598
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    • 2011
  • This study was intended to outline the characteristics of the food culture in the area of Kyungsangnamdo and its modernization by interpretation and analysis of the novel Toji, which was set in Hadong, Jinjoo in the area of Kyungsangnamdo in the early 20th century. The characteristics of the Kyungsangnamdo area's native dish during the Japanese ruling era in the latter half of the Choson dynasty are as follows. In the first part of the novel, which spans from 1897 to 1908, vegetable and grain food development can be seen in the area of Hadong, the interior plains of Kyungsangnamdo, where there is a typical farming village in the mountains. The second part of the novel, which spans from 1911 through 1917, includes some mentions of the properties of Kyungsangnamdo area's native dishes through the lens of emigrated Koreans living on Gando island. Gando island is in China, and is where Seohee, the heroine, escapes from her homeland and remains for a period of years. There is a unique type of seafood in the Gando area using fresh marine products, exactly the same as in the Kyungsangnamdo area. The third part of the novel spans 1919 through 1929, after Seohee returns to her own country and regains her house. There is a noticeable description of food culture in the area of Jinjoo in Kyungsangnamdo through the description of Seohee focusing on the education of her children. The well-described features of Jinjoo are boiled rice with soup of beef leg bones and Jinjoo bibimbob, with vegetables and a variety of foods using cod. Cod are caught in large quantities in Kyunjgsangnamdo, and cities in the area grow to medium size as the area became traffic-based. The fourth part of the novel spans from 1929 through 1938, and includes very detailed descriptions of characters and background locations. Salted fish combined with the wild ingredients of Mt. Jiri feature prominently in the Kyungsangnamdo's area descriptions. The fifth part spans from 1940 through 1945, and as the Japanese colonization era ends, the foods described in Kyungsangnamdo seem to develop the usage of soybean paste. With abundant fish and shellfish Kyungsangnamdo, the dishes that evolve to use soybean paste include mussel soybean paste soup, picked bean leaves in soybean paste, chaitgook - cold soup from soybean paste, and seolchigook used with seaweed and sea laver.

A Comparative Study on the Influences that 3 Faces of Intellect of Guilford Interact to Mathematics Teaching Patterns of 5 Categories of Higgins in a Viewpoint of Constructivism (Guilford의 지능 이론이 Higgins의 수업 형식에 미치는 영향에 대한 구성주의적 비교 연구)

  • Seo Sung Bo;Park Gyeong Suk
    • Journal of Elementary Mathematics Education in Korea
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    • v.3 no.1
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    • pp.1-20
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    • 1999
  • What do our mathematics teachers now do in the classroom? What does it actually mean to teach mathematics? Every preparatory mathematics teacher is confronted with these questions since they have studied to become a teacher. Almost all in-service teachers are faced by of questions, too, as they evaluate their teaching in the light of that of their colleagues. In this sense, Jon L. Higgins has proposed mathematics teaching patterns of five categories, i. e., exploring, modeling, underlining, challenging, and practicing, for the sake of our all teachers. Next, J. P. Guilford has suggested three faces of intellect presented by a single solid model, which we call the 'structure of intellect' Each dimension represents one of the modes of variation of the factors. It is found that the various kinds of operations are in one of the dimensions, the various kinds of products are in another, and the various kinds of contents are in the other one. In order to provide a better basis for understanding this model and regarding it as a picture of human intellect, I've explored it systematically and shown some concrete examples for its tests. Each cell in the model stands for a certain kind of ability that can be described in terms of operation, content, and product, for each cell is at the intersection uniquely combined with kinds of ope- ration, content, and product. In conclusion, how could we use the teaching patterns of five categories, that is, exploring, modeling, underlining, challenging, and practicing, according to the given mathematics learning substances? And also, how could children constitute the learning sub- stances well in their mind with a viewpoint of constructivism if teachers would connect the mathematics teaching patterns of five categories with any factors among the three faces of intellect? I've made progress this study focusing on such problems.

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Collaborative Filtering using Co-Occurrence and Similarity information (상품 동시 발생 정보와 유사도 정보를 이용한 협업적 필터링)

  • Na, Kwang Tek;Lee, Ju Hong
    • Journal of Internet Computing and Services
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    • v.18 no.3
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    • pp.19-28
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    • 2017
  • Collaborative filtering (CF) is a system that interprets the relationship between a user and a product and recommends the product to a specific user. The CF model is advantageous in that it can recommend products to users with only rating data without any additional information such as contents. However, there are many cases where a user does not give a rating even after consuming the product as well as consuming only a small portion of the total product. This means that the number of ratings observed is very small and the user rating matrix is very sparse. The sparsity of this rating data poses a problem in raising CF performance. In this paper, we concentrate on raising the performance of latent factor model (especially SVD). We propose a new model that includes product similarity information and co occurrence information in SVD. The similarity and concurrence information obtained from the rating data increased the expressiveness of the latent space in terms of latent factors. Thus, Recall increased by 16% and Precision and NDCG increased by 8% and 7%, respectively. The proposed method of the paper will show better performance than the existing method when combined with other recommender systems in the future.