• International Journal of Naval Architecture and Ocean Engineering
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• v.11 no.1
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• pp.82-96
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• 2019

A semi-submersible structure has been widely used for offshore drilling and production of oil and gas. The small water plane area makes the structure very sensitive to weight increase in terms of payload and stability. Therefore, it is necessary to lighten the substructure from the early design stage. This study aims at an optimization of hull structure based on a sophisticated yield and buckling strength in accordance with classification rules. An in-house strength assessment system is developed to automate the procedure such as a generation of buckling panels, a collection of required panel information, automatic buckling and yield check and so on. The developed system enables an automatic yield and buckling strength check of all panels composing the hull structure at each iteration of the optimization. Design variables are plate thickness and stiffener section profiles. In order to overcome the difficulty of large number of design variables and the computational burden of FE analysis, various methods are proposed. The steepest descent method is selected as the optimization algorithm for an efficient search. For a reduction of the number of design variables and a direct application to practical design, the stiffener section variable is determined by selecting one from a pre-defined standard library. Plate thickness is also discretized at 0.5t interval. The number of FE analysis is reduced by using equations to analytically estimating the stress changes in gradient calculation and line search steps. As an endeavor to robust optimization, the number of design variables to be simultaneously optimized is divided by grouping the scantling variables by the plane. A sequential optimization is performed group by group. As a verification example, a central column of a semi-submersible structure is optimized and compared with a conventional optimization of all design variables at once.

• Microbiology and Biotechnology Letters
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• v.50 no.1
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• pp.22-30
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• 2022

Haliotis discus hannai called abalone, is the valuable marine mollusks and the by-products of abalone processing are viscera. Brownish abalone male viscera (AMV), which have not been reported as having anti-inflammatory effects, was extracted with acetone and fractionated by different six acetone/hexane ratios (0, 10, 20, 30, 40, and 100%) using a silica column via in vitro ABTS and DPPH radical and nitric oxide (NO) production assay-guided fractionation. Among the fractions, the acetone/hexane ratio 40%, A40 exhibited the most potent radical scavenging activities and inhibition of lipopolysaccharide (LPS)-induced NO production without cytotoxicity. A40 inhibited LPS-induced intracellular reactive oxygen species (ROS) production in a dose-dependent manner. Western blot analysis revealed that A40 down-regulated the activation of NF-κB, MAPK (ERK 1/2, p-38, and JNK), and inflammatory enzymes, inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2. Moreover, this fraction inhibited the generation of pro-inflammatory cytokines such as interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α. These results suggested that AMV containing A40 with anti-inflammatory and anti-oxidantive effects, is the effective therapeutic and functional material for treating inflammatory disorders.

• International Journal of High-Rise Buildings
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• v.10 no.4
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• pp.311-321
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• 2021

Perception of the public to structural fires is very important because there are only a number of tall timber buildings constructed in the world. People are hesitating to accept tall timber buildings, so it is essential to ensure the first generation of tall timber buildings to a very high standard, especially fire safety. Right now, there are no specific design standards or regulations for fire design of tall timber buildings in Europe. Even though heavy timber members have better fire resistance than steel components, many conditions still need to be verified before considering the use of timber materials, e.g. fire spread, post-fire collapse, etc. This research numerically explores the structural behaviours of a tall Glulam building when one of its internal Glulam (Glued laminated timber) columns fails after sustaining a full 120-min standard fire and is removed from the established finite element building model created in SAP2000. The numerical results demonstrate that the failure and removal of the selected internal Glulam column may lead to the local failure of the adjacent CLT (Cross laminated timber) floor slabs, but will not lead to large disproportionate damage and collapse of the whole building. Here, the building is assumed to be located in Glasgow, Scotland, UK.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.1
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• pp.98-106
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• 2009

This work proposes a 1280-RGB $\times$ 800-Dot 70.78mW 0.l3um CMOS LCD driver IC (LDI) for high-performance 16M-color low temperature poly silicon (LTPS) thin film transistor liquid crystal display (TFT-LCD) systems such as ultra mobile PC (UMPC) and mobile applications simultaneously requiring high resolution, low power, and small size at high speed. The proposed LDI optimizes power consumption and chip area at high resolution based on a resistor-string based architecture. The single column driver employing a 1:12 MUX architecture drives 12 channels simultaneously to minimize chip area. The implemented class-AB amplifier achieves a rail-to-rail operation with high gain and low power while minimizing the effect of offset and output deviations for high definition. The supply- and temperature-insensitive current reference is implemented on chip with a small number of MOS transistors. A slew enhancement technique applicable to next-generation source drivers, not implemented on this prototype chip, is proposed to reduce power consumption further. The prototype LDI implemented in a 0.13um CMOS technology demonstrates a measured settling time of source driver amplifiers within 1.016us and 1.072us during high-to-low and low-to-high transitions, respectively. The output voltage of source drivers shows a maximum deviation of 11mV. The LDI with an active die area of $12,203um{\times}1500um$ consumes 70.78mW at 1.5V/5.5V.

• Korean Journal of Remote Sensing
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• v.39 no.5_1
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• pp.563-576
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• 2023

In this study nitrogen dioxide (NO₂), formaldehyde (HCHO) from the Ozone Monitoring Instrument (OMI) and TROPOspheric Monitoring Instrument (TROPOMI), OMI/ Microwave Limb Sounder (MLS) tropospheric column ozone (TCO), and Airkorea ground-based O₃ data were analyzed to examine the photochemical reaction relationship between tropospheric ozone and its precursors nitrogen oxides (NOx) and volatile organic compounds (VOCs). As a result of analyzing the trend of long-term changes from 2006 to 2020 using OMI satellite data, TCO showed an increasing trend, NO₂ steadily decreased, and HCHO continued to increase in Northeast Asia. In addition, formaldehyde nitrogen dioxide ratio (FNR; HCHO/NO₂ ratio), an indicator of ozone sensitivity, is gradually increasing, which means that the VOC-limited regime is decreasing. This study conducted a sensitivity analysis of ozone generation using TROPOMI FNR and ground-based ozone (O₃) over the recent years (2019~2022) to identify the possible cause for the continuous increase of ozone in Korea. Similar to the previous studies, VOC-limited and transitional regimes appeared in megacities, and VOC-limited regimes also appeared in areas where major power plants were located. In VOC-limited regimes, in other words, areas where NOx is excessively saturated, the reduction in NOx emissions may have weakened the ozone titration and thus led to the increase of ozone. Therefore, VOC emissions should be reduced in the short term rather than NOx emissions to reduce ozone concentrations under the VOC-limited regime.

• Journal of Energy Engineering
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• v.20 no.1
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• pp.13-20
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• 2011

The high fuel flexibility of Micro Gas Turbine(MGT) has boosted their use in a wide variety of applications. Recently, the demand for biogas generated from the digestion of organic wastes and landfill as a fuel for gas turbines has increased. We researched the influence of firing landfill gas(LFG) on the performance and operating characteristics of a micro gas turbine combined heat and power system. $CH_4$ and $CO_2$ simultaneous recovery process has been developed for field plant scale to provide an isothermal, low operating cost method for carrying out the contaminants removal in Land Fill Gas(LFG) by liquid phase catalyst for introduce into the green house for the purpose of $CO_2$ rich cultivation of the plants. Methane purification and carbon dioxide stripping by muti panel autocirculation bubble lift column reactor utilizing Fe-EDTA was conducted for evaluate optimum conditions for land fill gas. Based on inflow rate of LFG as 0.207 $m^3$/min, 5.5 kg/$cm^2$, we designed reactor system for 70% $CH_4$ and 27% $CO_2$ gas introduce into MGT system with $H_2S$ 99% removal efficiency. A green house designed for four different carbon dioxide concentration from ambient air to 1500 ppm by utilizing the exhaust gas and hot water from MGT system.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2005.10a
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• pp.57-78
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• 2005

The vehicle routing problem (VRP) is to determine a set of feasible vehicle routes, one for each vehicle, such that each customer is visited exactly once and the total distance travelled by the vehicles is minimized. A feasible route is defined as a simple circuit including the depot such that the total demand of the customers in the route does not exceed the vehicle capacity. While there have been significant advances recently in exact solution methodology, the VRP is not a well solved problem. We find most approaches still relying on the branch and bound method. These approaches employ various methodologies to compute a lower bound on the optimal value. We introduce a new modelling approach, termed route-splitting, for the VRP that allows us to address problems whose size is beyond the current computational range of set-partitioning models. The route-splitting model splits each vehicle route into segments, and results in more tractable subproblems. Lifting much of the burden of solving combinatorially hard subproblems, the route-splitting approach puts more weight on the LP master problem, Recent breakthroughs in solving LP problems (Nemhauser, 1994) bode well for our approach. Lower bounds are computed on five symmetric VRPs with up to 199 customers, and eight asymmetric VRPs with up to 70 customers. while it is said that the exact methods developed for asymmetric instances have in general a poor performance when applied to symmetric ones (Toth and Vigo, 2002), the route splitting approach shows a competent performance of 93.5% on average in the symmetric VRPs. For the asymmetric ones, the approach comes up with lower bounds of 97.6% on average. The route-splitting model can deal with asymmetric cost matrices and non-identical vehicles. Given the ability of the route-splitting model to address a wider range of applications and its good performance on asymmetric instances, we find the model promising and valuable for further research.

• Tunnel and Underground Space
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• v.22 no.1
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• pp.69-76
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• 2012

Theoretical backgrounds on the experimental methods of explosive welding, explosive forming and shock consolidation of powders are introduced. Explosive welding experiments of titanium (Ti) and stainless steel (SUS 304) plate were carried out. It was revealed that a series of waves of metal jet are generated in the contact surface between both materials; and that the optimal collision velocity and collision angle is about 2,100~2,800 m/s and $15{\sim}20^{\circ}$, respectively. Also, explosive forming experiments of Al plate were performed and compared to a conventional press forming method. The results confirmed that the shock-loaded Al plate has a larger curvature deformation than those made using conventional press forming. For shock consolidation of powders, the propagation behaviors of a detonation wave and underwater shock wave generated by explosion of an explosive are investigated by means of numerical calculation. The results revealed that the generation and convergence of reflected waves occur at the wall and center position of water column, and also the peak pressure of the converged reflected waves was 20 GPa which exceeds the detonation pressure. As results from the consolidation experiments of metal/ceramic powders ($Fe_{11.2}La_2O_3Co_{0.7}Si_{1.1}$), shock-consolidated $Fe_{11.2}La_2O_3Co_{0.7}Si_{1.1}$ bulk without cracks was successfully obtained by adapting the suggested water container and strong bonding between powder particles was confirmed through microscopic observations.

• Journal of Energy Engineering
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• v.25 no.4
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• pp.13-29
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• 2016

In this study, we analyzed the causes of major faults in the biogas plant through the case of gas engine failure when cogenerating electricity and heat using biogas as a fuel in the actual sewage treatment plant and suggested countermeasures. Hydrogen sulfide in the biogas entering the biogas engine and water caused by intermittent malfunction of the water removal system caused intercooler corrosion in the biogas engine. In addition, the siloxane in the biogas forms a silicate compound with silicon dioxide, which causes scratches and wear of the piston surface and the inner wall of the cylinder liner. The substances attached to the combustion chamber and the exhaust system were analyzed to be combined with hydrogen sulfide and other impurities. It is believed that hydrogen sulfide was supplied to the desulfurization plant for a long period of time because of the high content of hydrogen sulfide (more than 50ppm) in the biogas and the hydrogen sulfide was introduced into the engine due to the decrease of the removal efficiency due to the breakthrough point of the activated carbon in the desulfurization plant. In addition, the hydrogen sulfide degrades the function of the activated carbon for siloxane removal of the adsorption column, which is considered to be caused by the introduction of unremoved siloxane waste into the engine, resulting in various types of engine failure. Therefore, hydrogen sulfide, siloxane, and water can be regarded as the main causes of the failure of the biogas engine. Among them, hydrogen sulfide reacts with other materials causing failure and can be regarded as a substance having a great influence on the pretreatment process. As a result, optimization of $H_2S$ removal method seems to be an essential measure for stable operation of the biogas engine.

• Journal of Plant Biotechnology
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• v.40 no.3
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• pp.169-177
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• 2013

Recently, the number of people with diabetes is rapidly increasing, coupled with the fact that the insulin market is remarkably increasing. Therefore, molecular farming for plant-derived pharmaceutical protein production is reported as becoming more attractive than ever. In this study, we carried out experiments step by step for development of recombinant insulin constructs, which were transformed into E. coli system, in vitro transcription and translation system, and tobacco cells. At first, recombinant proinsulin protein was successfully produced in in vitro transcription and translation system with wheat germ extract. After which, recombinant construct of prominiinsulin encoded a fusion protein of 7.8 kDa with trypsin cleavage sites at N terminus and C terminus of minimized C-peptide was tried to in vitro expression using E.coli culture. After purification with His-tag column, the resulting recombinant prominiinsulin protein was processed with trypsin, and then checked insulin biosynthesis by SDS-PAGE and western blot analysis with anti-insulin monoclonal antibody. The immunoreactive product of trypsin-treated miniinsulin was identical to the predicted insulin hexamer. The construct of 35S promoter-driven preprominiinsulin recombinant gene with signal peptide region for ER-targeting and red fluorescence protein gene [N terminus ${\rightarrow}$ tobacco E2 signal peptide ${\rightarrow}$ B-peptide (1-29 AA) ${\rightarrow}$ AAK ${\rightarrow}$ A-peptide (1-21 AA) ${\rightarrow}$ RR ${\rightarrow}$ His6 ${\rightarrow}$ KDEL ${\rightarrow}$ C terminus] was transformed into BY-2 tobacco cells. A polypeptide corresponding to the 38-kDa molecular mass predicted for fusion protein was detected in total protein profiles from transgenic BY-2 cells by western analysis. Therefore, this recombinant preprominiinsulin construct can be used for generation of transgenic tobacco plants producing therapeutic recombinant insulin.