• 한국멀티미디어학회논문지
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• 제22권12호
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• pp.1339-1346
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• 2019

In the characteristic of the brain malignant, the blood vessels and tumors have the same color and shape, and the boundary distinction is not clear, Therefore, it is difficult to observe the naked eye. Because of the high invasiveness, the risk of recurrence is high. Therefore, complete resection of the tumor is essential. The method for distinguishing the boundary between blood vessels and tumors is a fluorescence contrast method using indocyanine green (ICG), a fluorescence contrast agent. In ICG, the concentration range analysis is very important because the fluorescence expression state varies depending on the concentration. However, since the analysis result of the fluorescence expression condition is insufficient according to the current concentration, this paper proposes by analyzing the initial protocol of the concentration range. 780 nm infrared light was irradiated to the ICG sample to observe the fluorescence expression through a near infrared (NIR) camera. The wavelength is measured by using a spectrum instrument (ocean view) to observe the fluorescence expression wavelength of 811nm. As a result of analyzing the mol concentration according to each sample, the fluorescence expression range was found to be 16.15-0.16M and the optimum fluorescence concentration on the brightest part was found to be 3.23-0.81M.

• 한국정보통신학회논문지
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• 제15권7호
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• pp.1564-1572
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• 2011

본 논문에서는 증강현실을 위한 히스토그램 기반의 손 인식 기법을 제안한다. 손동작 인식은 사용자와 컴퓨터 사이의 친숙한 상호작용을 가능하게 한다. 하지만, 비젼 기반의 손동작 인식은 복잡한 손의 형태로 인한 관찰 방향 변화에 따른 입력 영상의 다양함으로 인식에 어려움이 따른다. 따라서 본 논문에서는 손의 형태적인 특징을 이용한 새로운 모델을 제안한다. 제안하는 기법에서 손 인식은 카메라로부터 획득한 영상에서 손 영역을 분리하는 부분과 인식하는 부분으로 구성된다. 카메라로부터 획득한 영상에서 배정을 제거하고 피부색 정보를 이용하여 손 영역을 분리한다. 다음으로 히스토그램을 이용하여 손의 특징점을 구하여 손의 형태를 계산한다. 마지막으로 판별된 손인식 정보를 이용하여 3차원 객체를 제어하는 증강현실 시스템을 구현하였다. 실험을 통해 제안한 기법의 구현 속도가 빠르고 인식률도 91.7%로 비교적 높음을 확인하였다.

• 한국정보통신학회논문지
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• 제15권4호
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• pp.851-859
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• 2011

본 논문에서는 인간과 컴퓨터의 상호작용을 위해 연속된 입력영상에서 인체의 실루엣과 조인트를 자동추출하고 조인트를 추적함으로 객체를 추적하는 방법을 제안한다. 또한 추출된 조인트를 이용하여 인체를 매핑하여 사람의 동작을 재현한다. 이를 위해 인체의 치수를 이용하여 인체 움직임을 제어하는 14개의 조인트로 인체를 모델링한다. 제안방법은 단일카메라로 RGB 컬러로 입력되는 영상을 색상, 채도, 명암의 영상으로 변환한 후 차 영상기법을 이용하여 인체의 실루엣을 추출한다. 추출된 실루엣의 코너점과 인체 모델링 정보를 이용하여 조인트를 자동 검출한다. 객체의 움직임 추적은 전체 영상 중 조인트를 중심으로 블록매칭 기법을 이용하며 추출된 조인트의 위치정보를 이용하여 인체의 움직임을 매핑한다. 제안방법을 실험동영상에 적용한 결과 인체의 실루엣과 조인트를 자동 검출하며 추출된 조인트로 인체의 매핑이 효율적으로 이루어졌다. 또한 조인트의 추적이 매핑된 인체에 반영되어 인체의 움직임도 적절히 표현되었다.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 1993년도 Proceedings of International Conference for Agricultural Machinery and Process Engineering
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• pp.1243-1253
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• 1993

Visual features of a mushroom(Lentinus Edodes L) are critical in sorting and grading as most agricultural products are. Because of its complex and various visual features, grading and sorting of mushrooms have been done manually by the human expert. Though actions involved in human grading looks simple, a decision making undereath the simple action comes form the results of the complex neural processing of the visual image. And processing details involved in the visual recognition of the human brain has not been fully investigated yet. Recently, however, an artificial neural network has drawn a great attention because of its functional capability as a partial substitute of the human brain. Since most agricultural products are not uniquely defined in its physical properties and do not have a well defined job structure, a research of the neuro-net based human like information processing toward the agricultural product and processing are widely open and promising. In this pape , neuro-net based grading and sorting system was developed for a mushroom . A computer vision system was utilized for extracting and quantifying the qualitative visual features of sampled mushrooms. The extracted visual features and their corresponding grades were used as input/output pairs for training the neural network and the trained results of the network were presented . The computer vision system used is composed of the IBM PC compatible 386DX, ITEX PFG frame grabber, B/W CCD camera , VGA color graphic monitor , and image output RGB monitor.

• 방송공학회논문지
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• 제17권3호
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• pp.459-470
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• 2012

본 논문은 영상 보간법을 이용하여 저해상도 깊이맵을 고해상도 깊이맵으로 변환하는 방법을 제안한다. 현재의 카메라 센서는 고해상도 색상 영상을 제공하는데 반해, 깊이 측정 장치는 저해상도의 깊이맵을 주로 제공한다. 본 논문은 기존의 양선형 보간법, 고등차수 보간법, 양측 보간법을 바탕으로 깊이맵에서 추출한 고주파 성분을 적용하여 깊이맵의 선명도를 증가한다. 이를 위해, 제안 방법은 고주파 성분 추출 단계, 고주파 성분 적용 단계, 및 영상 보간 단계를 거친다. 실험에서는 다양한 깊이맵 데이터에 제안 방법을 적용하였는데, 성능검증 방법으로 선명도(sharpness degree)와 블러 메트릭 (blur metric)의 두 객관적 측정을 통해서 제안 방법이 기존 방법에 비해 선명도가 약 2배 정도 증가했음을 보여준다. 또한 블러 메트릭은 평균 14%가 감소되었다.

• Nutrition Research and Practice
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• 제10권4호
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• pp.393-397
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• 2016

BACKGROUND/OBJECFTIVES: Artemisinin, a natural product isolated from Gaeddongssuk (artemisia annua L.) and its main active derivative, dihydroartemisinin (DHA), have long been used as antimalarial drugs. Recent studies reported that artemisinin is efficacious for curing diseases, including cancers, and for improving the immune system. Many researchers have shown the therapeutic effects of artemisinin on tumors such as breast cancer, liver cancer and kidney cancer, but there is still insufficient data regarding glioblastoma (GBM). Glioblastoma accounts for 12-15% of brain cancer, and the median survival is less than a year, despite medical treatments such as surgery, radiation therapy, and chemotherapy. In this study, we investigated the anti-cancer effects of DHA and transferrin against glioblastoma (glioblastoma multiforme, GBM). MATERIALS/METHODS: This study was performed through in vitro experiments using C6 cells. The toxicity dependence of DHA and transferrin (TF) on time and concentration was analyzed by MTT assay and cell cycle assay. Observations of cellular morphology were recorded with an optical microscope and color digital camera. The anti-cancer mechanism of DHA and TF against GBM were studied by flow cytometry with Annexin V and caspase 3/7. RESULTS: MTT assay revealed that TF enhanced the cytotoxicity of DHA against C6 cells. An Annexin V immune-precipitation assay showed that the percentages of apoptosis of cells treated with TF, DHA alone, DHA in combination with TF, and the control group were $7.15{\pm}4.15%$, $34.3{\pm}5.15%$, $66.42{\pm}5.98%$, and $1.2{\pm}0.15%$, respectively. The results of the Annexin V assay were consistent with those of the MTT assay. DHA induced apoptosis in C6 cells through DNA damage, and TF enhanced the effects of DHA. CONCLUSION: The results of this study demonstrated that DHA, the derivative of the active ingredient in Gaeddongssuk, is effective against GBM, apparently via inhibition of cancer cell proliferation by a pharmacological effect. The role of transferrin as an allosteric activator in the GBM therapeutic efficacy of DHA was also confirmed.

• Journal of Korean Neurosurgical Society
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• 제58권6호
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• pp.513-517
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• 2015

Objective : Microscopic indocyanine green (ICG) angiography is useful for identifying the completeness of aneurysm clipping and the preservation of parent arteries and small perforators. Neuroendoscopy is helpful for visualizing structures beyond the straight line of the microscopic view. We evaluated our prototype of endoscopic ICG fluorescence angiography in swine, which we developed in order to combine the merits of microscopic ICG angiography and endoscopy. Methods : Our endoscopic ICG system consists of a camera, a light source, a display and software. This system can simultaneously display real-time visible and near infrared fluorescence imaging on the same monitor. A commercially available endoscope was used, which was 4 mm in diameter and had an angle of $30^{\circ}$. A male crossbred swine was used. Results : Under general anesthesia, a small craniotomy was performed and the brain surface of the swine was exposed. ICG was injected via the ear vein with a bolus dose of 0.3 mg/kg. Visible and ICG fluorescence images of cortical vessels were simultaneously observed on the display monitor at high resolution. The real-time merging of the visible and fluorescent images corresponded well. Conclusion : Simultaneous visible color and ICG fluorescent imaging of the cortical vessels in the swine brain was satisfactory. Technical improvement and clinical implication are expected.

• 한국정보통신학회논문지
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• 제13권11호
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• pp.2273-2276
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• 2009

요즘 부모들이 유아들의 음악 교육에 대해서 관심이 많아지면서, 유아들이 능동적으로 음악을 즐길 수 있도록 지원하는 시스템이 요구되고 있다. 따라서 본 논문에서는 실시간 손 인식 기법을 이용한 건반 연주 시스템을 제안한다. 제안하는 시스템은 유아들이 쉽게 사용할 수 있도록, 종이 건반위에서 손가락을 움직이기만 하면 음원이 재생되어 연주하는 환경을 제공한다. 그리고, 제안하는 시스템은 연주에 필요한 비용을 최소화하기 위해서, 보급형 컴퓨터와 종이건반, 웹 카메라, 스피커만을 이용한다. 또한, 효율적이고 정확하게 건반과 손가락을 인식하기 위해서, 건반 인식 단계와 손가락 인식 단계를 구분한다. 건반 인식 단계에서는 건반을 구성하는 검정색과 흰색만 고려하여 건반을 인식하고, 손가락 인식단계에서 는 피부색만 고려하여 손가락을 인식한다.

• 치과방사선
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• 제24권1호
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• pp.85-94
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• 1994

The purposes of this study were clinical comparison and evaluation between digital radiography and conventional radiography for the detection of artificial interproximal caries. Four freshly extracted, unrestored posterior teeth were obtained and caries was simulated by drilling semicircled defects with variable size at the interproximal surface of each tooth. The experiments were performed with IBM-PC/32 bit-DX compatible, video camera(VM-S8200, Hitachi Co., Japan), and color monitor(Multisync 3D, NEC, Japan). Sylvia Image Capture Board for the ADC(analog to digital converter) was used, and spatial resolution was 512 × 480 with 256 gray levels. The obtained results were as follows: 1. At the condition of under exposure, the radiographs were superior to the digital images in readability. Also, as the size of the artificial lesion was increased, readability of the radiographs was elevated. 2. The digital images were superior to the radiographs in readability especially under over exsposure. 3. As the exposure time and size of lesion was increased, the gray level of region of interest of the digital image was decreased proportionally. 4. As the F-value of average gray level of region of interest at individual exposure time and size of lesion, gray level of the all lesion sizes was decreased in comparison with that of the normal enamel.

• 천문학회지
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• 제46권6호
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• pp.253-259
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• 2013

We present near-infrared light curves of HBC 722 after its the September 2010 outburst. We have been monitoring its near-infrared light curves since November 2010 with Korean Astronomy and Space Science Institute Infrared Camera System (KASINICS). HBC 722 exhibits large changes in optical and near-infrared brightness since its outburst. The J, H, and $K_s$ light curves over about 2.5 years show that in all observed bands HBC 722 progressively became fainter until around April 2011, down to J ~10.7, H ~9.9, $K_s$ ~9.3, but it is getting brighter again. Large scatter in the obtained light curve prevents us from finding whether there is any short timescale variation as reported in other optical observations. The near-infrared color of HBC 722 is becoming bluer since its outburst. The pre-outburst Spectral Energy Distribution (SED) of HBC 722 is consistent with that of a slightly reddened Class II YSO with the exception of the extraordinary IR-excess in the far-infrared region.