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Development of targeted amplicon next-generation sequencing panel of 50 SNPs related to externally visible characteristics and behavior (외형 및 행동 습관 관련 50개 SNP 마커 분석을 위한 targeted amplicon next-generation sequencing 패널 개발)

  • Hee-Yeon Park;Yoonji Noh;Eung-Soo Kim;Hyun-Chul Park
    • Analytical Science and Technology
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    • v.37 no.3
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    • pp.189-199
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    • 2024
  • In forensic genetics, when it is not possible to confirm an individual's identity through STR profile analysis, additional information about the individual can be obtained using DNA-based phenotypic traits estimation. Recently, various researches have been conducted on methods to determine externally visible characteristics (EVC) such as eyes, hair, and skin color. However, relying solely on such phenotypic traits information has limitations for application in East Asian regions, including Korea. In this study, in order to utilize EVC related to an individual's appearance as investigative information, SNPs related to eye shape, hair thickness, skin color, as well as baldness, body type, high myopia, facial shape, acne, and behavioral habits were explored. A total of 50 SNPs were selected, and a targeted amplicon NGS panel capable of amplifying them all at once was developed. Experimental results confirmed the allelic types and frequencies of the 50 SNPs in 14 samples. We plan to use this panel to investigate the correlation between genotype and phenotype using various samples, and to develop methods for interpreting the results.

Automatic Estimation of Artemia Hatching Rate Using an Object Discrimination Method

  • Kim, Sung;Cho, Hong-Yeon
    • Ocean and Polar Research
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    • v.35 no.3
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    • pp.239-247
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    • 2013
  • Digital image processing is a process to analyze a large volume of information on digital images. In this study, Artemia hatching rate was measured by automatically classifying and counting cysts and larvae based on color imaging data from cyst hatching experiments using an image processing technique. The Artemia hatching rate estimation consists of a series of processes; a step to convert the scanned image data to a binary image data, a process to detect objects and to extract their shape information in the converted image data, an analysis step to choose an optimal discriminant function, and a step to recognize and classify the objects using the function. The function to classify Artemia cysts and larvae is optimally estimated based on the classification performance using the areas and the plan-form factors of the detected objects. The hatching rate using the image data obtained under the different experimental conditions was estimated in the range of 34-48%. It was shown that the maximum difference is about 19.7% and the average root-mean squared difference is about 10.9% as the difference between the results using an automatic counting (this study) and a manual counting were compared. This technique can be applied to biological specimen analysis using similar imaging information.

The Analysis of Industrial Difference in Skill Requirement for IT Personnel (정보기술 인력의 정보기술 스킬 요건 분석연구)

  • Oh, Seunng Hee;Park, Sang Hyeok;Cho, Nam Jae
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.9 no.3
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    • pp.187-194
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    • 2013
  • Being in era of the digital economy, the impact of IT on our economy more and more increased. Along with this effect, IT becomes origin of predominance of competition in every category of industry. Regarding new trends in industry, companies have to mutate their IT skill set. Every industry has their color and environment of IT and uncertainty is different. For a company, it is most important to plan own strategy with strategy view on industrial environment. The idea of this study is to find the difference of Skill Requirement in every category of industry by find what are the most important jobs and skills of IT in every industry. We set skills by categorized curriculum of specialized IT education center, then with IT specialist, checked and retouched the results and surveyed with IT people in every industry on skill set and job of IT. The result of this study can gives the idea to who design curriculum and build educational contents that would fulfill the need of field. Also, this study would be meaningful that it opens the field of study of skill requirement in Korea.

A Miniature Humanoid Robot That Can Play Soccor

  • Lim, Seon-Ho;Cho, Jeong-San;Sung, Young-Whee;Yi, Soo-Yeong
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.628-632
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    • 2003
  • An intelligent miniature humanoid robot system is designed and implemented as a platform for researching walking algorithm. The robot system consists of a mechanical robot body, a control system, a sensor system, and a human interface system. The robot has 6 dofs per leg, 3 dofs per arm, and 2 dofs for a neck, so it has total of 20 dofs to have dexterous motion capability. For the control system, a supervisory controller runs on a remote host computer to plan high level robot actions based on the vision sensor data, a main controller implemented with a DSP chip generates walking trajectories for the robot to perform the commanded action, and an auxiliary controller implemented with an FPGA chip controls 20 actuators. The robot has three types of sensors. A two-axis acceleration sensor and eight force sensing resistors for acquiring information on walking status of the robot, and a color CCD camera for acquiring information on the surroundings. As an example of an intelligent robot action, some experiments on playing soccer are performed.

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The correlation analysis of factors related to PMS through survey (월경전증후군과 관련된 요소를 분석하기 위한 설문조사 연구)

  • Cho, Jin-Hyong;Park, Ki-Bum;Kang, Hee-Chul;Kim, Dong-Il
    • The Journal of Korean Obstetrics and Gynecology
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    • v.19 no.4
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    • pp.174-204
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    • 2006
  • Purpose : The purpose of the present study was to know the correlation between PMS and personal factors as preceding research in order to make counter plan against PMS. Methods : Writer surveyed total 325 females(working 160 females and non-working 165 females) and made a statistical analysis in order to know the correlation between PMS and personal factors. Results : Factors that influence on PMS were caffeine intake, experience about taking contraceptive or not, family relations, annual income, now working or not, now taking exercise or not, stress, body mass index, experience of childbirth, color of menstruation, grade of menstrual pain, style of menstrual pain. Conclusion : Hereafter, we hope that this survey help Oriental Gynecological Clinic for treating PMS.

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Fiber Reinforced Inlay Adhesion Bridge

  • Cho, Lee-Ra;Yi, Yang-Jin;Song, Ho-Yong
    • The Journal of Korean Academy of Prosthodontics
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    • v.38 no.3
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    • pp.366-374
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    • 2000
  • FRC/ceromer system provides the clinician with a durable, flexible, and esthetic alternative to conventional porcelain fused to metal crowns. FRC is the matrix which is silica-coated and embedded in a resin matrix. The ceromer material which is a second generation indirect composite resin contains silanized, microhybrid inorganic fillers embedded in a light-curing organic matrix. FRC/ceromer restoration has a several advantages: better shock absorption, less wear of occluding teeth, translucency, color stability, bonding ability to dental hard tissues, and resiliency. It has versatility of use including inlay, onlay, single crown, and esthetic veneers. With adhesive technique, it can be used for single tooth replacement in forms of inlay adhesion bridge. In single tooth missing case, conventional PFM bridge has been used for esthetic restoration. However, this restoration has several disadvantages such as high cost, potential framework distortion during fabrication, and difficulty in repairing fractures. Inlay adhesion bridge with FRC/ceromer would be a good alternative treatment plan. This article describes a cases restored with Targis/Vectris inlay adhesion bridge. Tooth preparation guide, fabrication procedure, and cementation procedure of this system will be dealt. The strength/weakness of this restoration will be mentioned, also. If it has been used appropriately in carefully selected case, it can satisfy not only dentist's demand of sparing dental hard tissue but also patient's desire of seeking a esthetic restorations with a natural appearance.

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Naturalization of Implant Prostheses (자연감 있는 임플란트 보철물)

  • Kim, Dae-Hyun
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.8 no.1
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    • pp.96-103
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    • 1999
  • Restoration of missing oral tissues by using implant therapy is one of viable options in prosthodontic treatment. The purpose of oral rehabilitation are function, esthetics and phonetics. Recently, with the increasing esthetic demand of the patient, dentists and laboratory technicians are more concern ed about natural appearance of implant prostheses. There are so many factors which affect final esthetic results of treatment such a shape, color, proportion, gingival contour etc. To provide natural and vivid looking artificial prostheses to a patient, the careful diagnosis, treatment plan and laboratory Support is crucial. Several cases will be reviewed and discussed in terms of material, gingival shape, contour, speech and connection mode etc. to fabricate natural looking implant prostheses.

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Tracking and Capturing a Moving Object Using Active Camera Mounted on a Mobile Robot (이동로봇에 장착된 능동 카메라를 이용한 이동물체의 추적과 포획)

  • Park, Jin-U;Park, Jae-Han;Yun, Gyeong-Sik;Lee, Jang-Myeong
    • Journal of Institute of Control, Robotics and Systems
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    • v.7 no.9
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    • pp.741-748
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    • 2001
  • In this paper, we propose a method of tracking and capturing a moving object by a mobile robot. The position of the moving object is acquired from the relation through color-based image information from a 2-DOF active camera mounted on the mobile robot. The direction and rotational angular velocity of the moving object are estimated using a state estimator. A Kalman fiber is used as the state estimator for taking characteristics of robustness against noises and uncertainties included in the input data. After estimating the trajectory of the moving object, we decide on the optimal trajectory and plan the motion of the mobile robot to capture the target object within the shortest distance and time. The effectiveness of the proposed method is demonstrated by the simulations and experiments.

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Sign System of Common Spaces in Nursing Home (노인요양시설 공용생활공간의 안내표식 시스템에 관한 연구)

  • Chung, Mi-Ryum;Kim, Dae-Nyun
    • Korean Institute of Interior Design Journal
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    • v.18 no.5
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    • pp.200-210
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    • 2009
  • The Sign system of nursing home plays an important role when an elderly adapts to new environment and gets on daily life autonomously. Common living spaces are expecially important in maintaining social nature, adequate signage should be installed to aid them in finding their ways. Sign system is a comprehensive system consisted of various factors. In this research, it has been categorized as signage and cueing. Signage includes text and graphic signs, and cueing consists of floor plan configuration and sensual mechanism of visual, auditory, olfactory senses. Using this framework, held investigation and analysis were held in common area(shared living room, shared dining room, toilet) of 14 Korean, 8 Northern European, and 10 Japanese nursing home facilities. The result revealed that even though sign system should work as a combined unit, each factor was planed without relations to each other and did not perform mutually complementary role. Signage was installed too high, without considering the posture of elderly. Korean facilities used abundant and diverse signage compared to other countries. Japanese nursing home preferred cueing method over signage, and those of Northern Europe used plentiful visual cues such as color and ornaments.

Lighting Environment Design Research for Well-Being of Elderly People (고령자의 삶의 질 향상을 위한 조명환경 디자인 연구)

  • Yi, YonSoo
    • Korean Institute of Interior Design Journal
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    • v.26 no.5
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    • pp.34-41
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    • 2017
  • It is necessary to conduct a basic research on fusion of ighting design or lighting environment to improve the health and quality of life of elderly people. The purpose of this study is to analyze the lighting situation of elderly people 's residential facilities in terms of space environment design plan and to analyze the trends in smart home, design and technology. It is to provide basic data for the prototype of lighting fixtures for elderly people living facilities considering functional, physiological and emotional characteristics. For the study, the target sites were selected and the results of the illumination survey of the target facilities were divided into two types of spaces, residential and other public spaces, and their location, lighting fixtures' type, color temperature, illuminance. The results of the survey showed that the overall physical illumination compared to the recommended illuminance for the elderly satisfied the recommended range and provided the appropriate brightness for the elderly. However, in the application layout of the lighting fixtures, a monotonous arrangement and a lighting fixtures type consisting entirely of simple square type fixtures and downlight types were applied. It would be desirable to use different types of lighting fixtures in the design for various functions, such as making the environment more comfortable. Future research will propose a prototype for the design direction of the subdivided lighting fixtures that classify the space according to functions and understand the vision problem of the elderly while aesthetically.