• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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• pp.162-177
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• 2003

It has been known that the color of skin reflects the blood flow within. In lips, the capillaries close to the skin surface are numerous; hence lips are redder than the rest of face. However, dermatological research on lips is not as advanced as research on facial or body skin, and little was known about the relationship between relatively dull-colored lips and skin blood flow. The physiological differences between colorful and dull-colored lips were studied by a two-dimensional laser Doppler blood flow analyzer, a spectrometer for the measurement of the degree of oxygen saturation, and a confocal microscope for observing inside lips non-invasively. Dull-colored lips and the corner of lips (dull-colored compared to the center) showed relatively poor blood flow and lower oxygenated hemoglobin. It was found that colorful lips (generally the young) had a blood flow that tended to run straight in parallel with the skin surface. This unique blood-capillary structure can express clear red blood. Those with dull-colored lips had lost this unique structure. Their blood ran perpendicularly from the deep of the skin and down back again into the deep part as like the blood circulation patterns of facial skin. Therefore, the lips of the latter group had fewer blood capillaries near skin surface in the lips than that of the colorful-lips group. A lipstick containing a-glucosyl-hesperidin, which is derived from certain citrus fruits and can enhance blood circulation, was applied for evaluating its effects. Blood flow was increased 30 min after the application. After two weeks of daily application, the lips' condition became noticeably less dull. These findings suggest that the decrease of blood flow in dull-colored lips is caused by the loss of the unique capillary structure and the use of the lipstick to increase blood flow can give a vivid color to lips.

• 한국방사선학회논문지
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• 제17권5호
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• pp.751-759
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• 2023

유방 초음파 검사는 지방형 유방에서 영상화가 어렵고 미세 석회화를 찾는 데 어려움이 있지만, 미세 석회화의 발견은 유방암 선별 검사에 매우 중요하다. 초음파의 컬러 도플러 허상 중 반짝 허상은 영상에서 주로 결석이나 석회화 같은 강한 반사체에 발생되며 이를 이용한 평가 방법이 임상적으로 사용 중이다. 본 연구는 유방 석회화 중 가장 많이 차지하는 인산칼슘을 이용한 유방 모의 팬텀을 제작하여 초음파 장비의 컬러 도플러 설정 변수인 펄스 반복 주파수, 앙상블, 퍼시스트, 월 필터, 평활화, 선밀도, 임계값에 대해 실험을 진행했고 이를 통해 유방 초음파 검사에서 반짝 허상의 대조도를 개선하는 조건과 임상에서 이를 최대한 활용하기 위한 방안을 연구하고자 하였다. 그 결과 펄스 반복 주파수가 3.6 kHz ~ 7.2 kHz 범위에서 반짝 허상이 발생하며 10.5 kHz 이상에서는 발생하지 않았다. 앙상블의 경우 낮은 조건에서는 모든 크기의 석회화에 반짝 허상이 발생하였고 임계값 설정에서는 80에서 100 조건에서만 반짝 허상이 조금 증가했으며 1 mm 크기의 석회화에서는 발생하지 않았다. 퍼시스트, 월 필터, 평활화, 선밀도 설정은 반짝 허상이 발생하긴 했으나 조건별로 증가하지는 않아 설정 변수에 큰 의미가 없었으며 반짝 허상에 가장 큰 영향을 미친 것은 펄스 반복 주파수, 앙상블, 임계값으로 나타났다. 본 연구는 검사자가 컬러 도플러 설정을 조절하여 반짝 허상을 효과적으로 증가시키는 최적의 조건을 선택하는 데 도움이 될 것으로 사료된다.

• 한국임상수의학회지
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• 제19권2호
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• pp.268-271
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• 2002

Transitional cell carcinoma(TCC) was identified by cytological and ultrasonographic findings in an 11-year-old, intact female Yorkshire terrier with intermittent hematuria for three years. In color-doppler ultrasound images there was marked irregular wall thickness of the bladder surface and well-defined hyperechoic focal lesions within the mass. Active vascular response was observed in the surroundings of hyperechoic lesions.

• 한국임상수의학회지
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• 제19권1호
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• pp.95-99
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• 2002

A 6-month-old, intacted male dog was admitted to Seoul Animal Medical Center. The referring veterinarian suspected that the patient might have congenital cardiac problem. It was diagnosed with patent ductus arteriosus(PDA) based on the physical examination, auscultation, radiography, electrocardiography and ultrasonogrphy. After surgical ductus closure, there were improved clinical conditions through by alleviation of atrial fibrilation and left heart enlargement.

• 대한환경공학회지
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• 제31권6호
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• pp.442-448
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• 2009

예혼합 분무화염의 유적군 연소 기구를 평가하기 위하여 레이저 가시화법, MICRO (multi-color integrated Cassegrain receiving optics) 및 PDA (phase Doppler anemometer) 광학계측 시스템을 이용하여 동시 시계열 계측을 실시하였다. 또한 유적군의 군연소수를 실험적으로 산출하여 이론해석에 적용하였을 경우 실제로 관찰되는 군연소 형태와 일치하는지에 대하여 검토하였다. 유적군 단면화상에 의해 확인된 모든 유적군에 대하여 실험적으로 군연소수 $G_c$를 산출한 결과 주로 내부 군연소와 외부 군연소로 분류되었으며 이론해석과 일치하였다. 또한 실제 관찰된 군연소 형태와 그 유적군의 군연소수를 이론해석에 적용한 경우에 군연소 형태가 일치하는 경우와 일치하지 않는 경우가 있었다. 일치하지 않는 원인은 군연소수를 유적의 기하학적 배치만으로 결정한 것이나 현상의 3차원성이 측정 결과에 영향을 미친 것이라고 생각되어진다.

• Imaging Science in Dentistry
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• 제48권3호
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• pp.153-160
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• 2018

Purpose: This study aimed to assess the reliability of ultrasonography (US) in comparison with cone-beam computed tomography (CBCT) as a tool for monitoring the healing of jaw lesions. Materials and Methods: Twenty-one radiolucent lesions in jaws referred to the Oral Surgery Department at our institution were selected for this study. All lesions underwent CBCT and US examinations. The anteroposterior, superoinferior, and mesiodistal dimensions of the lesions were measured on CBCT and US images before surgery and at 6 months after surgery. The dimensions were compared between the US and CBCT images. Blood-flow velocity around the lesions was measured by color Doppler before surgery and at 1 week and 6 months after surgery to assess the capability of US to show changes in blood-flow velocity around the lesion. Results: Before surgery, there were no significant differences between US and CBCT in the mesiodistal and anteroposterior dimensions, although a significant difference was found in the superoinferior dimension (P<.05). However, at 6 months after surgery, significant differences were found between US and CBCT in all dimensions, and it is likely that the US measurements more accurately reflected the extent of healing. The average blood-flow velocity increased at 1 week after surgery (5.84 cm/s) compared with the velocity before surgery (4 cm/s) (P<.05). Then, at 6 months after surgery, the blood-flow velocity significantly decreased (3.53 cm/s) compared to the velocity measured at 1 week after surgery (P<.05). Conclusion: US with color Doppler was confirmed to be a more efficient tool than CBCT for monitoring bone healing.

• 한국임상수의학회지
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• 제20권3호
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• pp.274-277
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• 2003

임상적으로 건강한 비글견 17두와 췌장염으로 진단된 5두(요크셔테리어 3두, 토이푸들 2두)의 견에서, 화학보정 없이 전방 십이지장동맥(cranial pancreaticodudenal artery: cPDA) 혈관저항지수(resitive index: RI)를 측정하고 이를 비교 평가하였다. RI 측정을 위해 이중 펄스 색도플러 초음파와 11-MHz 선형 위상차 배열 탐촉자를 이용하였다. 췌장염견(0.75$\pm$0.04)견의 평균 RI는 정상견(0.63$\pm$0.04)과 비교하여 유의성(t = 5.79, p = 0.001)있게 증가된 소견을 보였다. 췌장염에 이환 또는 의증 환축에서는 cPDA의 RI 평가 또한 보조적 진단 가치가 있음을 확인하였다.

• Clinical and Experimental Reproductive Medicine
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• 제46권1호
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• pp.30-35
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• 2019

Objective: Bilateral uterine artery ligation (UAL) is a fertility-preserving procedure used in women experiencing postpartum hemorrhage (PPH). However, the long-term effects of this procedure on ovarian function remain unclear. The aim of this study was to investigate whether bilateral UAL compromised ovarian reserve and ovarian blood supply. Methods: This prospective study included 49 women aged between 21 and 36 years who had undergone a cesarean section for obstetric indications. Of these, 25 underwent uterine bilateral UAL to control intractable atonic PPH. The control group consisted of 24 women who had not undergone bilateral UAL. Standard clinical parameters, the results of color Doppler screening, and ovarian reserve markers were assessed in all participants at 6 months after surgery. The clinical parameters included age, parity, cycle history, body mass index, and previous medication and/or surgery. Color Doppler screening findings included the pulsatility index (PI) and resistance index (RI) for both the uterine and ovarian arteries. The ovarian reserve markers included day 3 follicle-stimulating hormone (FSH) levels, antral follicle count, and $anti-M\ddot{u}llerian$ hormone (AMH) levels. Results: There were no significant differences in the ovarian reserve markers of day 3 FSH levels, antral follicle count, and AMH levels between the study and control groups (p> 0.05 for all). In addition, no significant differences were observed in the PI and RI indices of the uterine and ovarian arteries (p> 0.05 for all). Conclusion: In this study, we showed that bilateral UAL had no negative effects on ovarian reserve or ovarian blood supply, so this treatment should be used as a fertility preservation technique to avoid hysterectomy in patients experiencing PPH.

• Imaging Science in Dentistry
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• 제52권2호
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• pp.209-217
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• 2022

Purpose: The aim of this study was, firstly, to determine the concordance of ultrasonographic and histopathological diagnoses in patients in whom apical resection was already indicated. Secondly, this study aimed to determine whether lesions were periapical granulomas or cysts, and to compare them after root canal treatment using ultrasonography and periapical radiographs. Materials and Methods: In the first stage of the study, ultrasonographic and histopathologic diagnoses of 10 lesions were compared. Secondly, the periapical radiographs and ultrasonographic images of 44 lesions were measured. The presence of internal vascularity was determined by ultrasonographic color and power Doppler modes. Follow-up examinations of healing after root canal treatment were performed using ultrasonography and periapical radiographs, and these modalities were compared. Results: In the periapical granuloma and cyst groups, the measurement values decreased for all variables. There was no significant difference in the dimensional changes of lesions between the 2 groups, and ultrasonography and periapical radiographs were compatible. The pre-diagnoses were compared with histopathological diagnoses and were found to be compatible. Conclusion: The ultrasonographic color and power Doppler techniques could be an effective method for diagnosing periapical lesions as cysts or granulomas. After root canal treatment of granulomas and cysts, the dimensional shrinkage and healing patterns appear to be similar. Ultrasonography and periapical radiographs were consistent in terms of dimensional comparisons, and ultrasonography may be an alternative method for follow-up of the healing of periapical lesions.

• Korean Journal of Radiology
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• 제22권11호
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• pp.1834-1840
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• 2021

Objective: To analyze the computational fluid dynamics (CFD) of femoral artery pseudoaneurysm (FAP), identify a suitable location and timing for percutaneous thrombin injection (PTI) based on this analysis, and report our clinical experience with the procedure. Materials and Methods: CFD can be used to analyze the hemodynamics of the human body. An analysis using CFD recommended that the suitable location of the needle tip for PTI is at the center of the aneurysm sac and the optimal timing for starting PTI is during the early inflow phase of blood into the sac. Since 2011, seven patients (three male and four female; median age, 60 years [range, 43-75 years]) with FAP were treated with PTI based on the devised suitable location and time. Prior to the procedure, color Doppler ultrasonography was performed to determine the location and timing of the thrombin injection. Results: The technical success rate of the PTI was 100%. The amount of thrombin used for the procedure ranged from 200 IU to 1000 IU (median, 500 IU). None of the patients experienced any symptoms or signs of embolic complications during the procedure. Follow-up CT images did not reveal any embolism in the lower extremities and showed complete thrombosis of the pseudoaneurysm. Conclusion: Based on our study of CFD, PTI administered centrally in the FAP during early inflow, as seen on color Doppler, can be an effective technique.