• Journal of the Korean Chemical Society
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• v.53 no.4
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• pp.399-406
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• 2009

The fluorescence study was performed to see whether the adsorption orientation of 4-biphenyl acetonitrile(BPAN) on metal colloids can be changed by forming an inclusion complex with $\alpha$-cyclodextrin($\alpha$-CD). The fluorescence quenching was observed with increasing temperature to confirm the direct adsorption of BPAN to the Au and Ag colloidal surfaces. BPAN adsorbed on the metal colloids formed inclusion complex with $\alpha$-CD regardless of the kinds of metal colloids. The formation constants, 32 $M^{-1}$ and 13 $M^{-1}$ for Au and Ag colloids respectively, were obtained with Benesi-Hildebrand plot. The molecules adsorbed on both the Au and Ag colloidal surfaces behaved similarly to each other, leading to the conclusion that the orientation of BPAN adsorbed on the metal colloids can be modified with $\alpha$-CD.

• 대한핵의학회:학술대회논문집
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• 1969.12a
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• pp.9.1-9.1
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• 1969

• Clean Technology
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• v.26 no.4
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• pp.251-256
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• 2020

The biocompatibility and plasmonic properties of Au nanoparticles make them useful for photothermal therapy, drug delivery, imaging, and many other fields. This study demonstrated a novel, facile, economic, and green synthetic method to produce gold nanoparticles. Gold nanoparticles (AuNPs) with spherical and triangular shapes were effectively synthesized using only Schisandra chenesis fruit extract as the capping and reducing agent. The shape of the AuNPs could be engineered simply by adjusting the molar concentration of HAuCl4 in the reaction mixture. The as-synthesized AuNPs were characterized using UV-VIS spectroscopy, transmission electron microscopy (TEM), X-ray diffraction (XRD), dynamic light scattering (DLS), and energy dispersive X-ray analysis (EDXA). This study revealed that by using the HAuCl4 concentration in the AuNP synthesis, the shape and size of the AuNPs could be controlled by the concentration of HAuCl4 and Schisandra chinensis fruit extract as a surfactant. The as-synthesized AuNPs samples had sufficient colloidal stability without noticeable aggregation and showed the predominant growth of the (111) plane of face-centered cubic gold during the crystal growth. The catalytic efficiency of the AuNPs synthesized using Schisandra chenesis fruit extract was examined by monitoring the catalytic reduction of 4-nitrophenol to 4-aminophenol using Ultraviolet-visible spectroscopy (UV-Vis spectroscopy). The synthesized AuNPs showed good catalytic activity to reduce 4-nitrophenol to 4-aminophenol, revealing their practical usefulness.

• Proceedings of the Korean Vacuum Society Conference
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• 2015.08a
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• pp.228.1-228.1
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• 2015

We demonstrate a simple route to hybridize two different nanomaterials by using three-dimensional nanodishes that can be used as small plasmonic containers to host guest nanoparticles. Our nanodishes were fabricated using nanoimprint lithography and oblique-angle film deposition, and the guest nanoparticles were drop-casted onto the host nanodishes. Based on the proposed method, colloidal Au nanoparticles were assembled inside Au nanodishes in the form of a labyrinth. These Au nanoparticle-nanodish hybrids excited a strong surface plasmon resonance, as verified by a numerical simulation of the local field enhancement and by direct observation of the enhanced Raman signals. Our results point to the potential of the nanodishes as a useful platform for combining diverse nanomaterials and their functionalities.

• Bulletin of the Korean Chemical Society
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• v.32 no.12
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• pp.4171-4175
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• 2011

Bio-functionalized gold nanoparticles (AuNPs), which bio-specifically interact with biotin-(strept)avidin, were investigated in this study. AuNPs were functionalized with a synthetically-provided biotin-linked thiol (BLT), which was synthesized by amidation of the active ester of biotin with 2-mercaptoethylamine. The BLT-attached AuNP was bio-specific for streptavidin, making it potentially useful for biosensor applications. To test the bio-specific interactions, the colors, absorption spectra and TEM images were investigated for proteins such as streptavidin, cytochrome C, myoglobin and hemoglobin. The colors and absorption spectra changed when streptavidin was added to the BLT-attached AuNP solution. However, the color and spectra did not change when the other proteins were added to the same solution. These results show that the AuNPs provided a colloidal solution with excellent stability and highly selective absorption characteristics for streptavidin as a target molecule. Proteins were also screened in order to identify a general strategy for the use of optical biosensing proteins based on AuNPs. In addition, TEM images confirmed that streptavidin led the BLT-attached AuNPs to aggregate or precipitate.

• Bulletin of the Korean Chemical Society
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• v.35 no.1
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• pp.45-50
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• 2014

A fully packed capillary electrochromatographic (CEC) microchip with an on-column micro-solid phase extraction (SPE) bed for the preconcentration and separation of organic analytes was prepared. A linear microchannel with monodisperse colloidal silica packing was formed on a cyclic olefinic copolymer microchip with two reservoirs on both ends. Silver-cemented silica packing frit structure was formed at the entrance of the microchannel by electroless plating treatment as a base layer. A gold coating was formed on it by reducing $Au^{3+}$ to gold with hydroxylamine. Finally micro-SPE bed was formed by self-assembly adsorption of 1-dodecanethiol on it. Micro-SPE beds were about 100-150 ${\mu}m$ long. Approximately $10^3$ fold sensitivity enhancements for Sulforhodamine B, and Fluorescein in nM concentration levels were possible with 80 s preconcentration. Basic extraction characteristics were studied.

• 대한핵의학회:학술대회논문집
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• 1969.12a
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• pp.10-10
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• 1969

• 대한핵의학회:학술대회논문집
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• 1970.10a
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• pp.87.2-88
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• 1970

• The Korean Journal of Nuclear Medicine
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• v.2 no.1
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• pp.53-58
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• 1968

Both primary hepatoma and amebic liver abscess are probably the most common space-occupying disease of the liver in Korea, and the importance of their accurate distinction can not be overemphasized. Radiogold hepatoscanning has been widely used at St. Mary's Hospital, and recently blood disappearance rate of colloidal $^{198}Au$ has been introduced in the study of hepatic ailments. A review of the literature revealed few previous publications concerning the differential features of the two conditions although some characteristic scan findings of each condition have been described. The present study is aimed at a critical review and analysis of various photoscan findings and blood disappearance rate determinations of colloidal $^{198}Au$ of 34 cases of primary hepatoma and 30 cases of amebic liver abscess. Among many scan manifestations, prominence of the uninvolved liver tissue, "hemispherical cold area," and splenic uptake are much more commonly encountered in primary hepatoma and the blood disappearance rate tends to be far more frequently delayed in primary hepatoma than in abscess providing at least a statistically useful basis of distinction of the two diseases.

• Journal of Microbiology and Biotechnology
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• v.17 no.6
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• pp.1031-1035
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• 2007

Prostate specific $antigen-{\alpha}_1-antichymotrypsin$ was detected by a double-enhancement strategy involving the exploitation of both colloidal gold nanoparticles (AuNPs) and precipitation of an insoluble product formed by HRP-biocatalyzed oxidation. The AuNPs were synthesized and conjugated with horse-radish peroxidase-PSA polyclonal antibody by physisorption. Using the protein-colloid for SPR-based detection of the PSPJACT complex showed their enhancement as being consistent with other previous studies with regard to AuNPs enhancement, while the enzyme precipitation using DAB substrate was applied for the first time and greatly amplified the signal. The limit of detection was found at as low as 0.027 ng/ml of the PSA/ACT complex (or 300 fM), which is much higher than that of previous reports. This study indicates another way to enhance SPR measurement, and it is generally applicable to other SPR-based immunoassays.