• BMB Reports
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• 제50권3호
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• pp.109-110
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• 2017

The nature of encoded information in neural circuits is determined by neuronal firing patterns and frequencies. This paper discusses the molecular identity and cellular mechanisms of spike-frequency adaptation in the central nervous system (CNS). Spike-frequency adaptation in thalamocortical (TC) and CA1 hippocampal neurons is mediated by the $Ca^{2+}$-activated $Cl^-$ channel (CACC) anoctamin-2 (ANO2). Knockdown of ANO2 in these neurons results in increased number of spikes, in conjunction with significantly reduced spike-frequency adaptation. No study has so far demonstrated that CACCs mediate afterhyperpolarization currents, which result in the modulation of neuronal spike patterns in the CNS. Our study therefore proposes a novel role for ANO2 in spike-frequency adaptation and transmission of information in the brain.

• Restorative Dentistry and Endodontics
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• 제20권2호
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• pp.732-743
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• 1995

The purpose of this study was to evaluate the adaptation of light cured dentin bonding agents to tooth structure by measuring contraction gaps on interfaces between cavity wall and composite resin under SEM study. In this study, class V cavities with cementum margin were prepared on the buccal surfaces of 15 extracted human premolar teeth and teeth were randomly assigned 3 groups of 5 teeth each. The cavities were filled with three dentin bonding agents and two composite resins were investigated for this study: three dentin bonding agents; Scotchbond 2, Scotchbond Multi-Purpose. All-Bond 2, two composite resins; Silux Pius, Z-100. Group 1 : Scotchbond 2 + Silux Plus Group 2 : Scotchbond Multi~Purpose + Z-100 Group 3 : All-Bond 2 + Z-100 The restored teeth were stored in 100% relative humidity at $37^{\circ}C$ for 7 days. And then, the roots of the teeth were removed with the tapered fissure bur and the remaining crowns were sectioned occlusogingivally through the center of restorations. Adaptation at tooth-restoration interface was assesed occlusally, gingivally, and axially by scanning electron microscope. The results were as follows : 1. In Group 1, the adaptation to dentinal wall of Scotchbond 2 was poor, but the adaptation to enamel wall of Scotchbond 2 was excellent. 2. In Group 2, the adaptation to occlusal was axial wall and gingival wall of Scotchbond Multi-Purpose was excellent. Especially in axially wall, the dentin bonding agents infiltrated into dentinal tubules and there was excellent adaptation to dentinal wall. 3. In Group 3, the adaptation to occlusal wall and axial wall of All-Bond 2 was excellent. But in gingival wall, there was gap formation between composite resin and dentin bonding agent.

• 보건의료산업학회지
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• 제7권3호
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• pp.111-123
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• 2013

The purpose of this study was to identify factors affecting stress and adaptation in newborn congenital heart disease patients of parents. Data were obtained through questionnaires from 181 newborn congenital heart disease inpatients of parents from P university in Y city. The data were analyzed SPSS 18.0, using descriptive statistics, Pearson correlation coefficients and stepwise multiple regression. Stress was negative correlated with level of patents adaptation. Social support, marital communication and family cohesion were positive correlated with level of patents adaptation. The explained variances for patents adaptation were 45.2% and factors affecting patients adaptation were congenital heart disease, family cohesion, stress, social support and marital communication. Educational intervention program for parents of newborn with congenital heart disease, reduce stress, and to increase the adaptation will be developed.

• 문화기술의 융합
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• 제7권3호
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• pp.255-260
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• 2021

본 연구는 중고령 성인학습자의 대학생활적응이 행복감에 미치는 영향을 알아보는데 목적을 둔다. 이를 위해 대구광역시 및 경북에 위치한 2년제 전문대학과 4년제 대학교에 재학 중인 중고령 성인학습자 321명을 대상으로 조사 및 분석하였으며, 그 결과는 다음과 같다. 첫째, 중고령 성인학습자의 일반적 특성에 따른 대학생활적응은 50대와 2학년, 건강상태가 좋은편이다가 높게 나타났고, 행복감은 여성과 60대, 3학년, 부부만 사는 가구형태에서 높게 나타났다. 둘째, 중고령 성인학습자의 대학생활적응과 행복감 간에는 정적 상관관계가 있으며, 그 중 내적성장 만족과 의미추구 만족의 상관관계가 가장 높게 나타났다. 셋째, 중고령 성인학습자의 대학생활적응이 행복감에 영향을 미치는 것으로 나타났으며, 대학생활적응의 하위요소인 성인학생관계적응이 행복감에 가장 큰 영향을 미쳤다. 이상의 연구결과는 대학생활에서 경험하는 다양한 긍정적인 경험이 학생 관계와 심리적인 안정감 및 육체적인 긴장을 완화시키고 내적인 성장에 대한 스스로의 만족감을 향상시킴으로 행복감에 영향을 줄 수 있음을 시사한다.

• International Journal of Advanced Culture Technology
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• 제10권3호
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• pp.1-10
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• 2022

This study examined the relationship between depression, anxiety, stress, and adaptation to college life of international students living in South Korea during the COVID-19 pandemic and the factors affecting the adaptation to college life. This study was carried out between December 3, 2021, to January 25, 2022, on international students living in South Korea. The questionnaires were composed of self-reported questionnaires, and the survey URL was sent as text messages to international students who understood the purpose and rationale of this study and consented to participate in the survey. The data were analyzed using SPSS WIN 22.0, and t-test, ANOVA, Pearson's Correlation Coefficient, and hierarchical regression were performed. As a result of the study, the average score of the study subjects was 8.44 points for depression, 8.28 points for anxiety, and 9. 28 points for stress. factors with significant differences in adaptation to college life according to general characteristics were living means and smoking. The relationship between the main variables, it was significant with depression (r=-.785, p<.001), anxiety (r=-.593, p<.001), and stress (r=-.726, p<.001). There was one negative correlation. It was found that the higher the depression, anxiety, and stress, the lower the college life adaptation. Lastly, depression (β=-.666, p<.001) was the factor affecting foreign students' adaptation to college life, and the explanatory power was 62%. Therefore, for international students to adapt to college life, it is necessary to establish an institutional strategy to detect depression, a negative psychological emotion, at an early stage and to systematically manage it. Also, it is necessary to find an intervention plan to relieve depression that can be applied in social isolation situations due to the spread of infectious diseases. Research confirming the intervention effect should be upgraded.

• 한국간호교육학회지
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• 제19권2호
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• pp.172-182
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• 2013

Purpose: This study was conducted to describe stress, stress coping, and school adaptation according to Myers-Briggs type indicator(MBTI) personality type in freshmen nursing students. Methods: This study was a cross sectional survey and the data was collected from 267 freshmen nursing students by means of self reported questionnaires from March 3 to 30, 2012. Collected data were analyzed on SPSS win 18.0. Results: 16 personality types were all seen in this study participants. There were no significant differences in stress, stress coping, and school adaptation according to 4 functions and 4 temperaments of MBTI. Conclusion: Nursing students show various personality types and we need to understand their diversity and reflect it to a school curriculum or education program development. Further study is required to identify the effects of self-understanding program on stress management and school adaptation.

• 대한임상검사과학회지
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• 제43권2호
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• pp.33-42
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• 2011

Zinc plays a key role in genetic expression, cell division, and cell growth and is essential for the functions of more than 450 metalloenzyme. There are high concentrations of zinc in pigment epithelium in bullfrog eye. Zinc deficiency causes night blindness and abnormal dark adaptation. The purpose of this study was to identify ERG (electroretinogram) b-wave sensitivity during light and dark adaptation in bullfrog retina after zinc and zinc chelators treatment such as histidine and TSQ (N-(6-methoxy-8-qunolyl)-p-toluenesulfon amide). Especially, we focused whether histidine act as a zinc chelator in the Muller cell. The results of our study are summarized as follows: 1) Both zinc and histidine elevated ERG b-wave amplitude and threshold in Muller cells by accelerating rhodopsin regeneration time and increased a-peak absorbance during light adaptation. 2) TSQ reduced those by prolonging rhodopsin regeneration time and decrement of a-peak absorbance during light adaptation. 3) Zinc shortened rhodopsin regeneration time and prolonged a-peak absorbance. These results suggested that histidine may act as a zinc-mediated transporter in presynaptic Muller cell membrane rather than zinc chelator and acts as a GABA-receptor inhibitor which blocks $Cl^-$ influx to the postsynapse.

• 대한의용생체공학회:의공학회지
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• 제29권1호
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• pp.25-31
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• 2008

It is well known that temporal information, i.e speech onset, about input speech can be represented to the response nerve signal of auditory nerve better depending on the adaptation effect occurred in the auditory nerve synapse. In addition, the performance of a speech processor of cochlear implant can be improved by the adaptation effect. In this paper, we observed the emphasis characteristic of speech onset in the recently proposed adaptation algorithm, analyzed the characteristic of performance change according to the variation of parameters and compared with transient emphasis spectral maxima (TESM) is the previous typical strategy. When observing false peaks which are generated everywhere except speech onset, in the case of the proposed model, the false peak were generated much less than in the case of the TESM and it is more distinguishable under noise.

• 인간식물환경학회지
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• 제23권1호
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• pp.77-85
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• 2020

The purpose of this study was to examine the effects of a healing garden program based on internal factors of vocational adaptation on career attitude for college students with developmental disabilities. First, healing garden program was defined by a group of experts related to education for developmental disabilities in the industry and academia through the focus group interview. Second, the healing garden program for college students with developmental disabilities was carried out for 15 weeks. Third, this study examined the effects of healing garden program based on internal factors of vocational adaptation on career attitude for college students with developmental disabilities. The participants of this study were 55 college students with developmental disabilities in N University, with 25 students placed in the experimental group and the other 30 in the control group. As a result of examination, the difference between before and after the program, it was found that factors of career attitude were improved significantly after the program in the experimental group, with Factor 1 (determination) increased from 2.08 to 3.39, Factor 2 (finality) from 2.28 to 3.19, Factor 3 (confidence) from 2.20 to 3.69, Factor 4 (preparation) from 2.12 to 3.79, and Factor 5 (independence) from 1.88 to 3.63. But the control group did not show a significant improvement after 15 weeks of the program except Factor 3 (confidence) and Factor 5 (independence). It was found that the healing garden program based on internal factors of vocational adaptation had effects on career attitude for college students with developmental disabilities. Finally, the program will contribute to vocational rehabilitation for college students with disabilities. The findings further suggest that healing gardening programs that facilitate career attitudes must be continuously developed and applied in order to establish effective transition from school to the world of vocational adaptation.

• 대한추나의학회지
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• 제3권1호
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• pp.55-64
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• 2002

Objectives : Acupuncture therapy is known as a effective method to CVA with paralysis. To make clear about effectiveness of acupuncture affecting to active and static postural adaptation for the patient with hemiparesis, we studied whether acupuncture changed ability of maintenance with one leg standing posture, and character of gait such as gait velocity, cadence, stride length, step length and base of support. Methods : This clinical study has been carried out with 10 cases of CVA patient with hemiparesis. We treated patients with acupuncture for 4 weeks, estimated each paralytic leg and well leg before 1st treatment and after last treatment, and compared the change of one leg with the other. To estimate the change of ability of static postural adaptation, we checked the time of duration with one leg standing posture. And about active postural adaptation, we used temporal distance gait analysis with Ink-Foot-Print method. Results and Conclusions : In static postural adaptation, paralytic leg significantly improved the duration with one leg posture. And In active postural adaptation with gait analysis, paralytic leg showed significant improvement in stride length and step length. Base of support and cadence were also significantly improved.