• Tuberculosis and Respiratory Diseases
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• 제44권5호
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• pp.1132-1139
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• 1997

기관지에서 점액상피양 종양은 드문 병변으로 대부분은 임상적으로 양성 경과를 보이는 저등급 암종이나 때로는 치명적인 고등급 암종을 보일 수 있으며 치료는 병리학적 등급에 관계없이 외과적 절제가 우선이다. 저자들은 호흡곤란을 내원하여 우폐 전체의 허탈 소견을 보인 임신 32주의 여자에서 조직학적으로 확인되어 수술한 저등급의 점액 상피양암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Journal of Yeungnam Medical Science
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• 제3권1호
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• pp.343-349
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• 1986

본 교실에서는 2례의 뇌간부위 병소에서 BRW system을 이용한 정위적 생검술을 시행하여 악성 신경교종 및 신경교 성상 세포종 Grade II로 확진된 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 대한물리치료과학회지
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• 제13권4호
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• pp.27-34
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• 2006

Purpose : The purpose of this study is to prove the increasing range of motion of joint to the patients of adhesive capsulitis of the shoulder applied the gliding-mobilization. Subjects and methods : The subjects are patients of adhesive capsulitis of the shoulder who have limited range of motion due to capsular pattern on the shoulder. The subjects are volunteer patients without a history of neuromuscular problems and randomly distributed into two groups. 15 experimental subjects(4 male, 11 female) received therapy with gliding-mobilization applied on limited shoulder joint and a second group with 15 control subjects(6 male 9 female) was treated by physiological passive range of motion therapy. The data were analyzed with paired t-test to determine striking differences depending on the course of treatment. Result : 1) In the group treated by gliding-mobilization the range of motion in shoulder flexion was increased in accordance to the course of treatment, and paired t-test showed striking differences(p<.05). 2) The range of motion in shoulder extension was increased in accordance to the course of treatment, and paired t-test showed striking differences(p<0.05). 3) The range of motion in shoulder abduction was increased with serise of treatment, and paired t-test showed striking differences(p<0.05). Conclusion : The gliding-mobilization increases the range of motion of the patient of adhesive capsulitis of the shoulder.

• 대한임상독성학회지
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• 제10권1호
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• pp.1-7
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• 2012

Purpose: Herbal preparations have long been used for medical purposes by traditional cultures, and their use is increasing in modern societies. However, many herbal agents produce specific cardiovascular toxicities in humans. We performed this study in order to investigate the clinical characteristics of the cardiac toxicities associated with herbal remedies. Methods: We conducted a retrospective study of 45 patients (mean age $57{\pm}10$ years) who presented with cardiotoxicity between January 2007 and May 2011 due to ingestion of herbal remedy substances. Patients were identified as suffering cardiotoxicity if they presented with chest pain, EKG abnormality, and elevation of cardiac enzyme. Results: Of the 45 total cases, 17 included hemodynamic instability (37.8%), 7 with increasing cardiac enzyme (15.6%), 2 with cardiac arrest (4.4%) and one case of mortality (2.2%). The cardiotoxic herb group that demonstrated the worst clinical course was Ranunculaceae. Conclusions: In our study results, 57.6% of the herbal intoxication patients demonstrated the effects of cardiotoxicity. Thus, we recommend careful monitoring of herbal intoxication patients.

• 실천공학교육논문지
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• 제13권2호
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• pp.243-249
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• 2021

대학 자체로 선정한 대학 고유의 핵심 6개 역량들 중에서 측정된 부족한 사항들을 강화시켜 교육 목표에 도달하기 위해, 학생 융합적 사고 역량과 자기 계발 역량을 최대화하는 집중 이수형 과목 형태로 공학 관련 전공 콜라주 과목을 신설하였다. 학부/학과간 공유형 교육과정으로 진행하였고, 2020학년 1,2학기 각각에서 2개 이수 집단(전기전자제어공학부 전자공학전공; 26명, 광공학과; 28명) 54명을 대상으로 공통된20개 문항들의 설문 결과를 종합, 분석하였다. 그 결과 응답자75% 이상이 장소와 시간에 자유로운 온라인 학습에 긍정적이었고, 녹화된 동영상 학습 시간내 추가적인 상호작용 활동들과 팀티칭(team teaching) 방식을 보강한 집중 이수 형태는 학습 효과를 극대화할 수 있다고 판단한다.

• 실천공학교육논문지
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• 제15권2호
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• pp.341-349
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• 2023

K대학교 차원에서 집중이수형 전공 지식 연결 과목으로 개설된 교과목에 대해, '콜라주(collage)' 명칭으로 2022학년 1학기에 전자공학전공학생(21명)들과 다른 14개 전공 학생들(26명)과 함께 47명의 수강인원을 구성하여, 융합형 5주 이수형 독립과목으로 진행하였고, 대상자에 대해 리커트(Likert) 5점 척도의 10개 문항들에 대한 응답 결과를 정리하였다. 정리된 결과들을 4개 항목들(신뢰도, 정규성, 상관성, 집단간 평균차 유효성)을 대상으로 검정을 진행하였고, 학습 주제의 난이도와 수강자의 학년에 따라 학습의 만족도에 차이가 있음을 확인하였으며, 상관성이 높은 5개 설문 항목들에서 수강자 65% 이상의 학생들이 '보통' 이상의 긍정 평가로 응답했음을 확인하였다.

• 한국학교보건학회지
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• 제5권1호
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• pp.74-83
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• 1992

The purpose of this study is to provide the basic data in developing environmental education curriculum by searching the consciousness junior-high school teachers in Seoul. 28 junior-high schools in Seoul were randomly selected and again selected 547 teachers to answer this questionnaire. The major findings of this study are as follows; 1. Teachers recognized the seriousness of environmental problems in the national level(about 54%) and Seoul level(about 90%) 2. Teachers recognized the need of environmental education at junior and high school(85%). 3. Only 17.5% of respondents marked to be selected Environmental Education at the 6th curriculum revision in their school. 4. If Environmental Education was selected at the 6th curriculum revision, about 58% of respondents recognized that Environmental Education Teacher should be responsible Environmental Education course. 5. If Environmental Education course was not selected at the 6th curriculum revision in their school, about 45% of respondents recognized that Environmental Education course should be done the whole subjects. 6. About 57% of respondents recognized that effective method of Environmental Education should be used audio-visual material. 7. About 25% of respondents recognized that environmental education should be prevented by Enterance-exam oriented education. Several improvements should be made on the following aspects; 1. At the 6th curriculum revision, Environmental Education course should be selected a required course. 2. At the Collage of Education, Environment-related course should be established. 3. Programs of environmental education should be urgently designed and improved so that teachers can proceed it more effectively.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.318.2-318.2
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• 2002

The effects of oxidative stress on the alterations of different antioxidant enzyme activity on mouse melanoma cells(B16F10) was investigated. Oxidative stress was induced by the exposeure to hydrogen peroxide(H2O2). B 16F 10 cells were exposed Phellinus linteus Ex. in combination with H2O2 and measured the time course of changes in cell viability and antioxidant enzyme activity. CAT activity peaked at 12 hr. On the contrary, SOD and GPX activity was maximum at 6 hr. The cell viability of Pheltinus linteus extracts in combination with hydrogen peroxide was higher than hydrogen peroxide alone.

• Journal of Industrial and Engineering Chemistry
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• 제68권
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• pp.238-245
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• 2018

The skin experiences constant physical stimuli, such as stretching. Exposure to excessive physical stimuli stresses the skin and can accelerate aging. In this study, we applied a method that allowed human fibroblasts and keratinocytes to be perfused with media to form 3D skin equivalents that were then uniaxially 10%-stretched for 12 h per day (at either 0.01 or 0.05 Hz) for up to 7 days to form wrinkled skin-on-a-chip (WSOC). There was more wrinkling seen in skin equivalents under 0.01 Hz uniaxial stretching than there was for non-stretched skin equivalents. At 0.05 Hz, the stratum corneum almost disappeared from the skin equivalents, indicating that stretching was harmful for the epidermis. At both frequencies, the production of collagen and related proteins in the skin equivalents, such as fibronectin 10 and keratin, decreased more than those in the non-stretched equivalents, indicating that the dermis also suffered from the repeated tensile stress. These results suggest that WSOCs can be used to examine skin aging and as an in vitro tool to evaluate the efficacy of anti-wrinkle cosmetics and medicines.

• Tuberculosis and Respiratory Diseases
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• 제51권6호
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• pp.540-549
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• 2001

연구배경 : 특발성 폐섬유화증 중 통상성 간질성 폐렴(Usual interstitial pneumonia)은 대부분 진행성으로 악화되는 매우 나쁜 질환이다. 조직학적으로 볼 때 상피하에 흩어져서 존재하는 fibroblastic foci에서 콜라겐 합성을 통한 폐 섬유화를 일으키는 것으로 알려져 있다. 이러한 fibroblastic foci와 폐기능을 포함한 임상적 지표 및 예후와의 상관관계를 알아보고자 하였다. 방 법 : 개흉 또는 흉강경을 통한 폐 생겸검사로 진단된 20명(남:여 13:7)을 대상으로 하여 폐 조직에서 fibroblastic foci의 양을 정량화 하였다. 결 과 : 1) Fibroblastic foci 양과, 폐기능검사, 동맥혈가스검사($AaDO_2$) 사이에는 유의한 상관관계가 없었으며, 기관지폐포 세척검사의 세포분획중 호중구 비율과는 의미있는 비례관계(p<0.05)가 있었다. 2) Fibroblastic foci/vol을 0.2를 기준으로 두 그룹으로 나누어 각 그룹간의 생존률, 폐기능검사, 기관판지폐포 세척검사의 세포분획비율의 차이를 비교한 결과 기판지폐포세척액의 호중구비율이 fibroblastic foci가 많은 군에서 의미있게 높았으며(p<0.05), 생존율, 폐기능점사등은 두 군간에 유의한 차이는 없었다. 결 론 : 본 연구에서는 fibroblasic foci가 UIP 환자의 예후 및 질환의 활성도를 나타내주는 지표로는 확실하지 않은 것으로 여겨지며, 추가로 좀더 많은 자료로 분석이 필요할 것으로 여겨진다.