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Bio-hybrid dental implants prepared using stem cells with β-TCP-coated titanium and zirconia

  • Safi, Ihab Nabeel;Hussein, Basima Mohammed Ali;Al-Shammari, Ahmed Majeed
    • Journal of Periodontal and Implant Science
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    • v.52 no.3
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    • pp.242-257
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    • 2022
  • Purpose: This study investigated periodontal ligament (PDL) restoration in osseointegrated implants using stem cells. Methods: Commercial pure titanium and zirconium oxide (zirconia) were coated with beta-tricalcium phosphate (β-TCP) using a long-pulse Nd:YAG laser (1,064 nm). Isolated bone marrow mesenchymal cells (BMMSCs) from rabbit tibia and femur, isolated PDL stem cells (PDLSCs) from the lower right incisor, and co-cultured BMMSCs and PDLSCs were tested for periostin markers using an immunofluorescent assay. Implants with 3D-engineered tissue were implanted into the lower right central incisors after extraction from rabbits. Forty implants (Ti or zirconia) were subdivided according to the duration of implantation (healing period: 45 or 90 days). Each subgroup (20 implants) was subdivided into 4 groups (without cells, PDLSC sheets, BMMSC sheets, and co-culture cell sheets). All groups underwent histological testing involving haematoxylin and eosin staining and immunohistochemistry, stereoscopic analysis to measure the PDL width, and field emission scanning electron microscopy (FESEM). The natural lower central incisors were used as controls. Results: The BMMSCs co-cultured with PDLSCs generated a well-formed PDL tissue that exhibited positive periostin expression. Histological analysis showed that the implantation of coated (Ti and zirconia) dental implants without a cell sheet resulted in a well-osseointegrated implant at both healing intervals, which was confirmed with FESEM analysis and negative periostin expression. The mesenchymal tissue structured from PDLSCs only or co-cultured (BMMSCs and PDLSCs) could form a natural periodontal tissue with no significant difference between Ti and zirconia implants, consequently forming a biohybrid dental implant. Green fluorescence for periostin was clearly detected around the biohybrid implants after 45 and 90 days. FESEM showed the invasion of PDL-like fibres perpendicular to the cementum of the bio-hybrid implants. Conclusions: β-TCP-coated (Ti and zirconia) implants generated periodontal tissue and formed biohybrid implants when mesenchymal-tissue-layered cell sheets were isolated from PDLSCs alone or co-cultured BMMSCs and PDLSCs.

The Changes of Social Distance, Disability Awareness, and Activity Satisfaction of Occupational Therapy Students through the Parachute Play (낙하산 놀이에 따른 작업치료과 학생들의 성인 지적장애인에 대한 사회적 거리감, 장애인식, 활동 만족도의 변화)

  • Kim, Su-Hyeon;Son, Sung-Min
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.3
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    • pp.393-402
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    • 2020
  • The purpose is to provide the basic information about the changes of the social distance, disability awareness, and activity satisfaction of the occupational therapy students through the parachute play. The subjects were 10 students in the third grade of the occupational therapy. They participated in the parachute play for 4 weeks. Their social distance, disability awareness and activity satisfaction were evaluated. The results showed the changes that the social distance was decreased, disability awareness and the activity satisfaction was increased after the play. Thus, to form the positive social distance and disability awareness and increase the activity satisfaction, the parachute play should be provided for the occupational therapy students.

Study about the Correlation Analysis between the Level of Smartphone Overdependence and Depression for Life Care of High School Students (고등학생들의 라이프 케어를 위한 스마트폰 과의존과 우울과의 관련성 연구)

  • Son, Sung-Min
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.4
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    • pp.309-315
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    • 2021
  • Purpose of this study is to analyze the correlation between the level of smartphone overdependence and depression among the high school student. Study subjects were 50 high school student. The assessment of the level of smartphone overdependence was used by the smartphone overdependence scale for adolescents and the assessment of the level of depression was used by Korean ver. of patient health questionnaire-9. As the results, the positive correlation was showed between the level of smartphone overdependence and depression and the statistically significant difference was showed. It was found that the higher the level of smartphone overdependence among high school students, the higher the level of depression. The smartphone overdependence among high school students could contribute to increase the level of depression. Thus, based on these results of this study, it is necessary to consider to reduce the level of smartphone overdependence and depression among high school students and subsequent studies should be conducted to clarify the casual relationship and influences of the level of smartphone overdependence and depression among high school students.

The Effect of Security Information Sharing and Disruptive Technology on Patient Dissatisfaction in Saudi Health Care Services During Covid-19 Pandemic

  • Beyari, Hasan;Hejazi, Mohammed;Alrusaini, Othman
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.16 no.10
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    • pp.3313-3332
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    • 2022
  • This study is an investigation into the factors affecting patient dissatisfaction among Saudi hospitals. The selected factors considered for analysis are security of information sharing, operational practices, disruptive technologies, and the ease of use of EHR patient information management systems. From the literature review section, it was clear that hardly any other studies have embraced these concepts in one as was intended by this study. The theories that the study heavily draws from are the service dominant logic and the feature integration theory. The study surveyed 350 respondents from three large major hospitals in three different metropolitan cities in the Kingdom of Saudi Arabia. This sample came from members of the three hospitals that were willing to participate in the study. The number 350 represents those that successfully completed the online questionnaire or the limited physical questionnaires in time. The study employed the structural equation modelling technique to analyze the associations. Findings suggested that security of information sharing had a significant direct effect on patient satisfaction. Operational practice positively mediated the effect of security of information sharing on patient dissatisfaction. However, ease of use failed to significant impact this association. The study concluded that to improve patient satisfaction, Saudi hospitals must work on their systems to reinforce them against the active threats on the privacy of patients' data by leveraging disruptive technology. They should also improve their operational practices by embracing quality management techniques relevant to the healthcare sector.

Preference and perception of low-sodium burger

  • Choi, Seung-Gyun;Yim, Sun-Goo;Nam, Sang-Myung;Hong, Wan-Soo
    • Nutrition Research and Practice
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    • v.16 no.1
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    • pp.132-146
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    • 2022
  • BACKGROUND/OBJECTIVES: Various sodium reduction policies have been implemented. However, there are limitations in the aspect of actual field applicability and efficiency. For effective sodium reduction, cooperation with the field is required and consumer preference must be considered. Thus, this study aimed to develop a low-sodium burger considering field applicability and consumer preference. MATERIALS/METHODS: Focus group interviews and in-depth interviews on the sodium reduction measures were conducted with nine professionals in related fields to discuss practical methods for sodium reduction from September 7 to 21, 2018. By reflecting the interview results, a burger using a low-sodium sauce was developed, and preference analysis for sodium in the burger sauces and finished products was performed. The consumer preference for low-sodium burgers was evaluated on 51 college students on November 12, 2018. RESULTS: The results of the professional interview showed that it is desirable to practice sodium reduction gradually, and by reflecting this, the burger sauce was prepared by adjusting the ratio of refined salt to 15%, 30%, and 50%. The sodium content of the burger using low-sodium sauce was 399 mg/100 g in the control group, 362 mg/100 g in the H1 group, and 351.5 mg/100 g in the H2 group, showing a 9.3-11.9% decrease in sodium in the H1 and H2 groups. The preference evaluation on the low-sodium burgers showed a higher preference for burgers with 9.3-11.9% sodium reduction, which did not affect the overall taste. CONCLUSIONS: This study examined the potential for sodium reduction in the franchise foodservice industry. An approximate 10% sodium reduction resulted in an increase in consumer preference without affecting the strength of the taste. Thus, if applied gradually, sodium reduction at practical levels could increase the consumer preference without changing the taste or quality and could be applied in the franchise foodservice industry.

Changes of Problem Behavior, Sleep Quality, and Quality of Life of the People with Intellectual Disability Through the Application of Heavy Work Activities (힘든 일 활동의 적용에 따른 지적장애인의 문제행동과 수면의 질, 삶의 질의 변화)

  • Son, Sung-Min
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.7
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    • pp.501-509
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    • 2020
  • The purpose of this study was to provide basic information about the analysis of the changes in problem behavior, sleep quality and quality of life of the people with intellectual disability through the application of the heavy work activities. This study subjects were 10 people with intellectual disability and they participated in the this activities for 12 weeks. Through the application of heavy work activities, Korean-Adaptive Behavior Scale was used to analyze the changes in problem behavior, sleep quality assessment was used to analyze the changes in sleep quality and satisfaction with life scale was used to analyze the changes in quality of life. As the results, the decrease of problem behavior, the improvement of sleep quality and quality of life were showed. Heavy work activities should be act to decrease the problem behavior, improve sleep quality and quality of life of the study subjects. Thus, heavy work activities should be considered to apply for the people with intellectual disability.

Relationship Between Titleist Performance Institute Level 1 Test and the Performance of Professional Golf Players (프로 골프선수의 TPI Level 1 Test Score에 따른 경기력 수준 분석)

  • Kim, Jae-Eun;Do, Kwang-Sun;Kim, Cheong
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.2
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    • pp.27-35
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    • 2022
  • Purpose : The purpose of this study is to analyze the correlation between the TPI Level 1 test and the performance of KPGA professional golf players. Methods : In 2019, 30 KPGA golf players attempted in the TPI Level 1 test. Their performance was then compared with the test based on the players' aggregated official records on the KPGA website, The most meaningful prize money ranking, average driving distance, fairway landing rate, and average number of putts were considered to evaluate their performance. Additionally, to obtain the average value of the players' accumulated records, the period from the first game in March 2019 to the end of October was considered. Results : The criterion for the difference between the upper group and the lower group was set based on the 9 points of the TPI Level 1 test, which showed the most significant difference. The prize money ranking stood at 63.00±51.77 in the upper group and 113.92±68.79 in the lower group in the TPI Level 1 test, the difference was significantly higher (p<.05) for the upper group (p<.05). The average driving distance was 286.15±10.06 yds for the upper group and 277.39±8.49 yds for the lower group, group, with the driving distance significantly higher in the upper group (p<.05). Further, the average number of putts for the upper group was 1.81±.02 and 1.85±.04 for the lower group, indicating a significant difference. Conclusion : A higher TPI Level 1 test score is likely to have a positive effect on performance.. As a result of the statistical values of this study, it was found that players must possess at least 9 out of 17 types of physical abilities Therefore, it can be considered that training and intervention to acquire these physical abilities are essential.

Effects of Dietary Therapy with Korean Herbal Medicine and Cultivated Wild Ginseng Pharmacopuncture on Change of Body Composition: A Retrospective Study (산삼복합약침과 한약을 병행한 식이요법이 체성분 변화에 미치는 영향: 후향적 연구)

  • Lee, Jin-Hyuck;Kim, Seon-Jong;Lim, Jung-A;Shin, Jung-Min
    • Journal of Korean Medicine for Obesity Research
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    • v.22 no.1
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    • pp.86-92
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    • 2022
  • The purpose of this study was to investigate the effects of dietary therapy with Korean herbal medicine and cultivated wild ginseng pharmacopuncture on change of body composition retrospectively. We analyzed the medical records of 26 patients, who carried out dietary therapy with Korean herbal medicine and cultivated wild ginseng pharmacopuncture at Moemfit Clinic, Charmjin Oriental Medicine for 8-12 weeks. And exercise and nutrition were recommended self-developed food, Moemfit Shake, Moemfit Hankki and walking exercise for one hour a day. The body composition values (body weight, body mass index, body fat mass, skeletal muscle mass, waist-hip ratio, visceral fat area, percent body fat) decreased after dietary therapy with Korean herbal medicine and cultivated wild ginseng pharmacopuncture significantly. But, percent skeletal muscle increased significantly. Results from this investigation showed that dietary therapy Korean with herbal medicine and cultivated wild ginseng pharmacopuncture has positive effects on changes of body compositions.

A case of cataract surgery using phacoemulsification in a 12-year-old poodle

  • Kang, Myeong-Gon;Han, Dong-Hyun;Han, Sei-Myoung;Jung, Eun-Gyeom;Kim, Gyeong-Min;Cho, Jae-Hyeon;Koh, Phil-Ok;Won, Chung-Kil;Kim, Chung-Hui;Lee, Dongbin
    • Korean Journal of Veterinary Service
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    • v.45 no.3
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    • pp.221-228
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    • 2022
  • Cataracts occur commonly in older dogs, which can lead to partial or complete vision loss. In the present study, a 12-year-old male poodle presented for evaluation of ocular sinister (OS) cataract. This study was a clinical case report on the process of performing surgery using phacoemulsification (PHACO) and the problems that arise in patient diagnosed with OS cataract. In the oculus dexter (OD), the artificial eye was inserted because there was no electroretinography (ERG) response. In the OS, the ERG was 51.6 μV, so operation was performed because the visual pathway function remained. Slit-lamp biomicroscopy of the OS showed complete loss of vision as a hypermature cataract and that the lens was hardened. During the cataract surgery using PHACO, visco-elastic agents were used to maintain the shape of the eyeball, and the PHACO procedure took 3.13 minutes. The hardened lens and visco-elastic agents were removed from the eye through PHACO surgery, and the operation was completed by inserting an intraocular lens (IOL). As a result of managing IOP for 2 months after surgery, it remained stable at a maximum of 19 mmHg, and no postoperative ocular hypertension (POH) occurred. Currently, one year has passed since the operation, and the dog maintains its daily life with its left eye without any problems.

A Systematic Review on the Effects of Group Art Therapy on the Older with Dementia (집단미술치료가 치매 노인에게 미치는 영향에 대한 체계적 고찰)

  • Kim, Do-Yoen;Lee, Hye-Mi;Bae, Ji-Woo;Jung, Nam-Hae
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.4
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    • pp.71-81
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    • 2022
  • Purpose : This study aimed to present evidence by analyzing the characteristics and effectiveness of group art therapy interventions through an examination of domestic studies on group art therapy for older people with dementia. Methods : The database used DBpia, Riss, and Google Scholar, and the research period was from 2016 to November 2021. For the selected studies, the level of evidence was analyzed, bias evaluation was performed, and patient, intervention, comparison, and outcome were analyzed. For the evaluation of bias, the risk of bias assessment tool for non-randomized study (RoBANS) and Cochrane's risk of bias (RoB) were used. Results : As for the level of evidence of the included studies, level I consisted of five studies, and levels II and III each had one article. As a result of the bias evaluation of five studies through RoB, a "low risk of bias" was found for incomplete result data, selective result reporting, and others, except for four unclear evaluation areas. The "low risk of bias" ratio was 0~25 % in the evaluation of bias in two studies through RoBANS. For the evaluation tool, cognitive evaluation tool was used the most while mini-mental state examination-Korea was used the most frequently. For the intervention method, the most frequently used was group art therapy that employed recall in three studies, while collage, Korean painting, use of paper media, and procedural memory were used in each of the other studies. Each intervention was found to be significantly effective overall. Conclusion : This study provided clinical evidence by systematically reporting research on group art therapy for older people with dementia. In the future, it is necessary to check the effect of group art therapy on various areas other than cognition for older people with dementia. Moreover, the study should be conducted with the risk of bias sufficiently taken into consideration.