• Title/Summary/Keyword: Cold test

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The Effect of Tongkyu-tang on the Ovalbumin-inhalation Rat Model with Allergic Rhinitis (통규탕(通竅湯)이 알레르기 비염 모델 횐 쥐에 미치는 영향)

  • Jung, Jin-Young;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.18 no.2
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    • pp.36-50
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    • 2005
  • Background and Objectives: Allergic rhinitis is an allergic reaction characterized by sneezingm itchy nose, mouth and throat, congestion and/or nasal discharge. The offending allergenes are usually pollens, molds, dust mites and animal allergen. Recently, the incidence of infectious nasal diseases tend to decrease. However, allergic rhinitis has increased and treatment in most cases has only deat with the symptom. Tongkyu-tang was composed of sixteen crude drugs. The Oriental Medical References mention therapeutic effects of Tongkyu-tang on nasal obstruction, watery nasal discharg. And Tongkyu-tang has clinically been used for the treatment of common cold, headache, sternutation, rhinitis etc. Speacially Tongkyu-tang is one of the most frequently used medical treatment for the allergic rhinitis. Experimental studies were conducted to investigate for the effect of Tongkyu-tang on the changes of neutrophil segment, lymphocyte, total IgE and nassal tissue in allergic rhinitis of ovalbumin-inhalation rat. Meterial and Methods: Fifteen Sprague-Dawley rats were divided into three group: normal group, control group, experimental group. To induce the allergic rhinitis in control group and experimental group, rats were sentitized intraperitoneally with 0.1 % ovalbumin solution 3 times at intervals of I week. Then intranasal sensitization was performed by diffusing 0.1 % ovalbumin solution 3 times at intervals of 2 days. After that time, rat in the experimental group were oral administration treated by Tongkyu-tang for 28 days. We observed changes in nasal tissue; changes in the number of white blood cell, red blood cell and total Ig E; also changes in the segment of neutrophil and lymphocyte in blood. And we observed the changes of AST, ALT of three group. We used anova test statistically. Result: The number of leucocyte remained unchanged between three group. The number of erythrocyte was increased in experimental group and control group when compared with the normal group. The segment of neutrophil, in blood was decreased in experimental group when compared with the control group but, that was not significant statistically(p<0.05). The promotion of lymphocyte in blood was significantly decreased in experimental group when compared with the Control group(p<0.05). Total IgE was decreased in experimental group when compared with the control group but, that was not significant statistically(p<0.05). The cilium be well preserved in experimental group: the nasal tissue in experimental group was similar to in the normal group. Congestion and expantion of grandular cell in nasal submucosa, hypertropy of epithelium in nasal mucosa, acid mucus in epithelium and neutral mucus in subepithelium were decreased in experimental group when compared with the control group. Effect of Tongkyu-tang on the liver function were also studies in rats. Treatment of Tongkyu-lang did not affected on AST and ALT. Conclusion: Considering the above experimental results, it is suggested that oral administration treatment using Tongkyu-lang, without worry about liver function injury, decreased response on an Animal model with Allergic Rhinitis.

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A Preliminary Study with the Objective of Developing a Community based Postpartum Women's Follow-up Program (지역사회 중심의 산욕기 산모 추후관리 프로그램 개발을 위한 기초조사)

  • Kim Myoung Hee
    • Journal of Korean Public Health Nursing
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    • v.15 no.1
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    • pp.27-41
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    • 2001
  • The purpose of this study was to discern the level of satisfaction of postpartum care in hospitals. the level of importance of traditional postpartum care and the need for home health care for postpartum women. The study's design was to obtain data needed to develop a community-based postpartum care program and to improve the quality of nursing for postpartum care recipients. Data for the study was collected from 1 March to 31 June 2000 from 116 postpartum care recipients treated in Chung-Buk, Korea. Data analysis consisted of frequency, percentage, t-test, and ANOVA. using SPSS win program. The results the of analysis were as follows: 1) The level of satisfaction of postpartum care in the hospital (mean 1.31) was very low. The most laudable items of nursing care by category were: moderate satisfaction with 'perineal wound care' (2.04) and 'afterpain observation'(2.09). The overall level of satisfaction of postpartum care in the hospital. however, was very low. 2) Among other items of postpartum care in the hospital, 'postpartum exercise' $(25.9\%)$. 'assessment and support for postpartum depression' $(25.9\%)$, 'operation wound care for women who underwent Caesarean sections' $(24.5\%)$. and 'contraception and family planning' $(20.4\%)$ showed a need for home health care for postpartum care recipients above $20\%$. 3) The level of importance of traditional postpartum care (Sanhujori) was relatively high (mean 2.72). The importance of Sanhujori by category was as followed: 'the fourth principle: protecting the body from harmful strains' was the highest (2.88), 'the third principle: eating well', 'the first principle: invigorating the body by augmenting heat and avoiding cold', 'the second principle: resting without working', 'the fifth principle: keeping clean' and 'the sixth principle: handling with the whole heart' showed 2.85, 2.80, 2.70, 2.51 and 2.46 respectively. 4) The need for home health care with Sanhujori was very low. 5) The relationship between demographic factors and the level of satisfaction with postpartum care in the hospital was as follows: the satisfaction levels were significantly different among' delivery frequency' and 'health status' alteration after delivery'. 6) The relationship between demographic factors and the importance of the Sanhujori category was as follows: There were no significant differences in the level of importance of the first and the forth principle of Sanhujori. The level of importance of the second principle of Sanhujori was significantly different among 'income' and 'family type'. The level of importance of the third principle of Sanhujori was significantly different among 'having a boy'. The level of importance of the fifth principle of Sanhujori was significantly different among 'income' and 'feeding type'. The level of importance of the sixth principle of Sanhujori was significantly different among 'education background' and 'feeding type'. In conclusion. the findings of this study illustrate the nursing needs of postpartum care recipients. It provides a challenge to caregivers in the healthcare industry to develop a continuous postpartum care program and integrative postpartum care system that embodies the oriental and western paradigm for the promotion of women's health.

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An Experimental Study of Strength Evaluation in Frozen Soils according to Direct Shear Box Systems (직접전단상자 시스템에 따른 동결토의 강도 평가에 관한 실험적 연구)

  • Kim, Sang Yeob;Kim, YoungSeok;Lee, Jangguen;Lee, Jong-Sub
    • Journal of the Korean GEO-environmental Society
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    • v.18 no.3
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    • pp.5-14
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    • 2017
  • Experimental study on strength characteristics of frozen soils is necessary for the safety evaluation of design and construction in cold region. The objective of this study is to evaluate the direct shear strength of frozen soils obtained from traditional system (Type-1), system with roller on the upper shear box (Type-2), and system with fixed upper shear box separated from bottom shear box (Type-3). Specimens mixed with sand, silt, and water are frozen to $-5^{\circ}C$, and then direct shear tests are conducted under the normal stress of 5, 10, 25, and 50 kPa. Experimental results show that the upper shear box of Type-1 touches the bottom shear box due to the rotation of the upper shear box. The shear strength obtained from Type-2 is overestimated because the preventing rotation force is added to shear force. Type-3 may acquire the only strength of the specimen, and shear strain at peak shear strength is similar to that at the beginning of vertical displacement occurrence. In addition, internal friction angle and cohesion at both peak and residual stresses in Type-3 are smaller than those of Type-2. This study shows that high strength specimens including frozen soils can be effectively evaluated using improved shear box system such as Type-3.

Evaluation of Thermoregulatory Properties of Thermal Underwear Named as 'Heating Underwear' using Thermal Manikin and Human Performance Test ('발열내복'이라 광고되는 시판 기능성 보온내복의 써멀 마네킹과 인체 착용 실험을 통한 체온조절 성능 평가)

  • Lee, Hyo-Hyun;Lee, Young-Ran;Kim, Ji-Eun;Kim, Siyeon;Lee, Joo-Young
    • Fashion & Textile Research Journal
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    • v.17 no.4
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    • pp.657-665
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    • 2015
  • This study evaluated the thermoregulatory properties of functional thermal underwear ('heating underwear') in markets using a thermal manikin and human wear trials. One ordinary thermal underwear (ORD) and two functional thermal underwear (HEAT1 and HEAT2; manufactured goods, HEAT1: moisture absorbing heat release mechanism, HEAT2: heat storage, release mechanism) were chosen. Thermo-physiological and subjective responses were evaluated at an air temperature of $5.0{\pm}0.5^{\circ}C$ and air humidity of $30{\pm}5%RH$ with five male subjects ($21.6{\pm}1.3yr$ in age, $178.0{\pm}5.9cm$ in height, $68.2{\pm}5.9kg$ in body mass). Experimental conditions consisted of four ensembles that included winter clothes (Control: no underwear, ORD, HEAT1, HEAT2). Water-vapor resistance was greater in fabric of HEAT1 than others. The results were: 1) Total thermal insulation (IT) using a thermal manikin were not greater for HEAT1 (0.860clo) and HEAT 2 (0.873clo) than for ORD (0.886clo). 2) There were no significant differences in rectal temperature, mean skin temperature, heart rate and total body mass loss between the four conditions. Microclimate clothing temperature on the back was greater for ORD than for HEAT1 and HEAT2. Subjects felt more comfortable with HEAT1 than for others at rest. HEAT2 was higher in microclimate humidity when compared to other conditions. The results suggest that thermoregulatory properties of 'heating underwear' in market did not differ from those of ordinary thermal underwear in terms of total thermal insulation and thermoregulatory responses in a cold environment.

A Clinical Analysis of Surgically Managed Thyroid Nodule (외과적으로 치료한 갑상선 결절에 대한 임상적 고찰)

  • Jung In-Kyu;Kim Lee-Su;Choi Won-Jin
    • Korean Journal of Head & Neck Oncology
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    • v.9 no.1
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    • pp.16-24
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    • 1993
  • During 7 years, from Jan. 1986 to Dec. 1992, authors studied 208 cases of the surgically managed thyroid nodules at the Department of General Surgery, Han Kang Sacred Heart Hospital and obtained the following results. 1) Among the total 208 cases, male to female ratio was 1:11.2 in benign thyroid diseases and 1:9 in malignant thyroid diseases. The benign disease was prevalent between second and forth decade comparing with malignant disease between third and fifth decade. 2) The most common duration of illness was 3 months(26.0%). 3) Palpable neck mass was the most common chief complaint(100%). Palpitation. fatigue, and sweating were common complaints in patient with benign disease, and fatigue, palpitation, and sweating in malignant disease in decreasing order of frequency. 4) 55.8 % of lesions were in right lobe, 33.2% in left lobe, 5.8% in diffuse type, 4.8% in bilateral lobes, and 0.5% in isthmus. 5) The most common size of nodule was between 2.0cm and 3.9cm in diameter, which consisted of 55.1% of benign disease and 48.0% of malignant disease. 6) 86.5% of thyroid function test showed euthyroidism, 10.1% hyperthyroidism, and 3.4% hypothyroidism. 7) Thyroid scanning of 176 patients revealed cold nodules in 92.5% of benign diseases and in 92.9% of malignant diseases. 8) The most common benign disease was adenomatous hyperplasia(62.7%), and the most common malignant disease was papillary adenocarcinoma(80.0%). 9) Fine needle aspiration cytology was performed in 91 cases, and it showed 69.0% of sensitivity, 90.3% of specificity, and 83.5% of accuracy. 10) Frozen biopsy was performed in 109 cases. and it showed 93.9% of sensitivity, 100.0% of specificity, and 98.2% of accuracy. 11) The most commonly performed operation was unilateral lobectomy(including unilateral lobectomy with isthmectomy)(79.1%) in benign disease. and total thyroidectomy(62.0%) in malignant disease. 12) Postoperative complication showed 5 cases of wound infection (2.4%), 3 cases of transient hypoparathyroidism(1.4%), 3 cases of transient hoarseness(1.4%), 2 cases of postoperative bleeding(1.0%), 1 case of permanent hypoparathyroidism(0.5%), 1 case of permanent hoarseness(0.5%), and 1 case of postoperative pneumonia (0.5%).

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HEAT PIPE TYPE EXHAUST HEAT RECOVERY SYSTEM FOR HOT AIR HEATER

  • Kang, G.C.;Kim, Y.J.;Ryou, Y.S.;Rhee, K.J.
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 2000.11c
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    • pp.654-661
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    • 2000
  • Area of greenhouse increases rapidly up to 45,265ha by the year of 1998 in Korea. Hot air heater with light oil combustion is the most common heater for greenhouse heating in the winter season. However, exhaust gas heat discharged to atmosphere through chimney reaches up to 10~20% of total heat of the oil combusted in the furnace. In order to recapture the heat of this exhaust gas and to recycle for greenhouse heating, the heat pipe type exhaust heat recovery system was manufactured and tested in this experiment. The exhaust heat recovery system was made for space heating in the greenhouse. The system consisted of a heat exchanger made of heat pipes, ${\emptyset}15.88{\times}600mm$ located in the rectangular box of $600{\times}550{\times}330mm$, a blower and air ducts. The rectangular box was divided by two compartments where hot chamber exposed to exhaust gas in which heat pipes could pick up the heat of exhaust gas, and by evaporation of the heat transfer medium in the pipes it carries the heat to the cold compartment, then the blower moves the heat to greenhouse. The number of heat pipe was 60, calculated considering the heat exchange amount between flue gas and heat transfer capacity of heat pipe. The working fluid of heat pipe was acetone because acetone is known for its excellent heat transfer capacity. The system was attached to the exhaust gas path. According to the performance test it could recover 53,809 to 74,613kJ/hr depending on the inlet air temperature of 12 to $-12^{circ}C$ respectively when air flow rate $1,100\textrm{m}^3/hr$. The exhaust gas temperature left the heat exchanger dropped to $100^{circ}C$ from $270^{circ}C$ by the heat exchange between the air and the flue gas, the temperature difference was collected by the air and the warm air temperature was about $60^{circ}C$ at the air flow rate of $1,100\textrm{m}^3/hr$. This heat pipe type exhaust heat recovery system can reduce fuel cost by 10% annually according to the economic analysis.

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Assessment of Vibration Produced by the Grinder Used in the Shipbuilding Industry and Development of Prospective Prevalence Model of Hand-arm Vibration Syndrome (선박건조업에서 사용되는 그라인더의 진동평가와 수지진동증후군 예측 모델 개발)

  • Yim, Sanghyuk;Lee, Yunkeun;Park, Hee-Sok
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.16 no.4
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    • pp.398-412
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    • 2006
  • The purpose of this study is to investigate the relationship between the acceleration of vibration by the powered hand tools used in the shipbuilding industry, and to develop the prospective prevalence model for the hand-arm vibration syndrome among the shipbuilding workers.The acceleration levels and frequencies of six types of grinder were measured using the ISO5349 method along with the time of exposure to the vibration from the powered hand tools. Medical examination for 114 workers were performed using the cold provocation test. Comparisons were made between the estimated prevalence of hand-arm vibration syndrome from ISO5349 and the observed values from the medical examinations. By multiple regression, we developed the prospective prevalence model of hand-arm vibration syndrome produced by the hand tools used in the shipbuilding industry. 4 hour-energy-equivalent frequency-weighted accelerations were $6.23m/s^2$ in the grinding job done after welding, and $13.39m/s^2$ in the grinding job done before painting. The mean exposure time while holding powered hand tools was 4.64 hours. Prevalence rates of Raynaud's Phenomenon were 12.04% in the grinding after soldering, and 42.9% in the grinding before painting measured using the ISO5349 method. After exposure to vibration for 10.79 years, about a half of the workers in the grinding after welding could developed Raynaud's Phenomenon. For the workers in the grinding before painting, the latency was 5.02 years. The ISO equation for dose response relationship was not significantly correlated with observed recovery rates of finger skin temperatures, blood flows and amplitudes of nerve conduction velocities. A multiple regression model for dose-response relationship was proposed from the results. Recovery rate of the skin temperatures = -0.668+ 0.337 ${\times}$ 4 hour energy equivalent frequency-weighted accelerations + 0.767 ${\times}$ duration of vibration exposure(years) The validity was proved by multiple regression analysis after correlation transformation and regression results based on model-building data and validation data.

Micronucleus Test of DW-166HC, a Novel Radiopharmaceutic Anticancer Agent (신규 방사성 항암제 DW-166HC의 소핵시험)

  • Moon, Eun-Yi;Lee, Jin;Lee, Won-Yong;Choi, Chung-Ha;Lee, Dog-Keun;Ryu, Jei-Man;Chung, Yong-Ho;Yoon, Sung-June;ark, Kyung-Bae
    • Biomolecules & Therapeutics
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    • v.5 no.3
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    • pp.278-283
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    • 1997
  • DW-166HC ($^{166}$ Holmium ($^{166}$ Ho)-Chitosan complex) is a new radiopharmaceutic anticancer agent with a broad anti-tumoriginec spectrum, especially against human fepatic cancer. DW-166HC was evaluated for the appearance of micronucleus in polychromatic erythrocytes (PCEs) of mouse bone marrow cells after subcutaneous and intravenous single administration. Bone marrow cells were prepared at 24 hr and 48 hr after DW-166HC-I ($^{165}$ Ho-Chitosan complex cold compound) administration and at 24 hr, 72 hr and 2 weeks after DW-166HC ($^{166}$ Ho-Chitosan complex : hot compound) administration. The results showed there was no statistically significant increase of the numbers of PCEs with micronucleus in all DW-166HC-I administered groups compared with a negative control group but there was statistically significant increase of the numbers of PCEs with micronucleus at 24 hr and 72 hr in all DW-166HC administered groups, which was recovered after 2 weeks from the drug administration. The results also showed the ratio of normochromatic erythrocytes (NCEs) to PCEs of all DW-166HC-I administered groups was not significantly different from that of a negative control group but there was significant difference this ratio at 24hr and 72 hr in all DW-166HC administered groups compared with that of negative group, which was also recovered after two weeks from the drug administration. These results suggested that DW-166HC-I may not cause any chromosomal damage but DW-166HC has in vivo mutagenic potential because of its radioactivity.

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Evaluation on the In-plane Bending Moment for T-joints with Square Hollow Structural Sections (각형강관 T형 접합부의 면내 휨모멘트 평가)

  • Park, Keum Sung;Lee, Sang Sup;Choi, Young Hwan;Bae, Kyu Woong
    • Journal of Korean Society of Steel Construction
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    • v.21 no.5
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    • pp.451-459
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    • 2009
  • The purpose of this study was to evaluate the in-plane bending moment for T-joints made of cold-formed square hollow steel sections. In the previous studies, the T-joint was shown not to have an obvious peak load, and the failure mode was the main chord flange failure at the branch-width-to-chord-width ratio ($\beta$) of below 0.71. Based on the experimental results, including the tests conducted by Zhao, the deformation limit of 1% B was proposed for ${16.7{\leq}2{\gamma}(=B/T){\leq}33}$ and ${0.34{\leq}{\beta}(=b_{1}/B){\leq}0.71}$. Then, the ultimate in-plane bending strength was shown to be Mu=1.5${\cdot}$M1% B. The existing strength formulae for the original T-joint were investigated and were determined to be the main chord flange failure for the branch-squared T-joint. The bending strength formulae of CIDECT and other researchers were compared with the test results. Finally, a reasonably good agreement with Zhao's formula was found. Therefore, the design guidelines were presented based on Zhao's strength formula for T-joints.

A Study on Digital Infrared Thermographic Imagic Characters of women suffering from Postpartum disease (DITI를 이용한 산후풍 환자의 체표 온도 특성 연구)

  • Park, Kyoung-Sun;Lee, Yoon-Jae;Hwang, Deok-Sang;Lee, Jin-Moo;Lee, Chang-Hoon;Cho, Jung-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub
    • Journal of Oriental Medical Thermology
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    • v.6 no.1
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    • pp.49-55
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    • 2008
  • Purpose: During Postpartum period many women complain multiple pain, cold hypersensitivity, hot flush, sweating and so on. We call the postpartum disease as San Hu Pung. We studied characters of DITI Characters of women suffering from Postpartum disease. Methods: We studied 55 patients visiting OOhospital from February 2006 to November 2007. The subjects were categorized in two groups, symptom group(37) and no symptom group(18). We measured the temperatures of abdomen(CV17, CV12, CV4), upper and lower limb(PC8, LU4, LR3, ST32) and back(GB21, BL18, BL53). We studied the difference of DITI between two groups by Student T-test using SPSS for windows (version 12.0). Results: The general characteristics such as age, days of postpartum, primiparity, cesarean section, partum season, breast-feeding of two groups were not different statistically. Temperatures of abdomen(CV17, CV12, CV4) and back(GB21, BL18, BL53) of two groups were not different statistically. Temperatures of Lt. PC8 and both LR3 of symptom group were statistically higher than no symptom group. The difference between Lt. PC8 and LU4, both LR3 and ST32 of symptom group were statistically higher than no symptom group. Conclusion: The results suggest that women suffering from Postpartum disease shows high temperature on hand and foot. It seems that postpartum disease patients tend to have blood deficiency. DITI can be useful to diagnose San Hu Pung. The more studies to diagnose San Hu Pung would be needed.

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