• Food Science of Animal Resources
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• v.44 no.3
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• pp.607-619
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• 2024

Probiotics are functional microorganisms that exhibit various biological activities, such as allergic reactions, inflammation, and aging. The aim of this study is to evaluate the effects of Bifidobacterium lactis CBT BL3 (BL) on the amyloid beta (Aβ)-mediated cognitive impairments. Oral administration of live BL to intracerebroventricularly Aβ-injected mice significantly attenuated short- and long-term memory loss estimated using the Y-maze and Morris water maze tests. We found that expression of apoptosisrelated proteins such as caspase-9, caspase-3, and cleaved poly (ADP-ribose) polymerase was significantly elevated in the brain tissues of Aβ-injected mouse brains when compared to that of the control mouse group. Interestingly, these expression levels were significantly decreased in the brain tissue of mice fed BL for 6 wk. In addition, the abnormal over-phosphorylation of mitogen-activated protein kinases (MAPKs) such as ERK1/2, p38 MAPK, and JNK in the brain tissue of intracerebroventricularly Aβ-injected mice was significantly attenuated by oral administration of BL. Taken together, the results indicate that Aβ-induced cognitive impairment may be ameliorated by the oral administration of BL by controlling the activation of MAPKs/apoptosis in the brain. This study strongly suggests that BL can be developed as a functional probiotic to attenuate Aβ-mediated cognitive deficits.

• Journal of Korean Academy of Nursing
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• v.42 no.1
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• pp.56-65
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• 2012

Purpose: This study was done to evaluate the effects of cognitive behavioral therapy in a victimized community district and to determine if the program is an effective nursing intervention to reduce posttraumatic stress disorder symptom, depression and state anxiety. Methods: A nonequivalent control group design was used for the study. The participants, 32 elementary school students, were selected from grades 4, 5, 6 and each student was assigned to either the experimental (16) or control (16) group. Cognitive behavioral therapy was used as the experimental treatment from April 9 to May 28, 2009. The experimental group received cognitive behavior therapy intervention 8 times. Data analysis was done using ANCOVA with SPSS 17.0. Results: After the intervention, the experimental group showed significantly lower levels of posttraumatic stress disorder symptoms than the control group. Conclusion: The findings from this study suggest that cognitive behavioral therapy is an effective nursing intervention to decrease the level of mental health problems of children in victimized district. Further research is required in order to identify the continuous effects of cognitive behavioral therapy.

• Journal of Korean Academy of Nursing
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• v.27 no.1
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• pp.36-48
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• 1997

This survey was performed to evaluate and compare cognitive function, self-esteem and depression in the elderly related to aging. The data were collected from 200 elders in eight homes for the elderly in Taegu. Data collection was done from June 1 to 31, 1996. The scale used to measure cognitive function was the MMSE-K(Mini-Mental State Examination-Korea), Self-esteem was measmed using Rosenberg's self-esteem scale and depression using SDS(Self-rating Depression Scale). A comparison of cognitive function, self-esteem and depression by aging were summarised as follows : 1. There were significant differences on the cognitive function score in the elderly according to age group(F=24.81, P<.01). 2. There were significant differences on the self-esteem score in the elderly according to age group(F=3.84, P<.5). 3. There were significant differences on the depression score in the elderly according to age group (F=5.90, P<.1). 4. The general characteristics which affected the cognitive function scores of the elders were sex (F=8.45, P<.5), educational level(F=8.86, P<.5), spousing(F=34.59. P<.01), and the perception of health(F=4.63, P<.5). 5. The general characteristic which affected the self-esteem scores of the elders was the perception of health(F=3.81. P<.5). 6. The general characteristic which affected the depression scores was the educational level(F=3.96, P<.5).

• Korean Journal of Adult Nursing
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• v.29 no.2
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• pp.177-189
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• 2017

Purpose: A meta-analysis was conducted to identify the effect of cognitive improvement programs for the elderly with mild cognitive impairment (MCI) in Korea. Methods: Five databases, as well as relevant reference lists, of studies published from 2000 to 2016, were searched. Fourteen studies were identified. Quality assessments of included studies were conducted using the Scottish Intercollegiate Guidelines Network checklist. An R program was used to analyze effect sizes and to identify possible sources of heterogeneity among studies. The potential for publication bias was investigated using a funnel plot, Egger's regression test and sensitivity analysis. Results: The total effect size was large (Standardized Mean Difference [SMD]=1.44, 95% CI: 1.11~1.77), with cognition based intervention (SMD= 1.77, 95% CI: 1.26~2.29) and exercise intervention (SMD=1.13, 95% CI: 0.82~1.44). Statistically significant moderators were identified intervention type by meta-ANOVA analyses. Finally, no significant evidence of publication bias was found. Conclusion: There is clear evidence that cognitive improvement programs can greatly enhance cognition in elderly with MCI. Future research should examine the effects of non-pharmacological interventions targeting elderly populations with mild-to-severe cognitive impairment in order to develop and enhance the effectiveness of cognitive improvement programs in Korea.

• Korean Journal of Adult Nursing
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• v.21 no.3
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• pp.339-348
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• 2009

Purpose: We aimed to describe and compare the cognitive function, anxiety, and quality of life for the demented elderly in day care centers or nursing homes. Methods: We selected 44 subjects from day care centers and 63 subjects from nursing homes by performing convenience sampling. The Korean version of Mini Mental Status Examination was used for measuring cognitive status; Rating Anxiety in Dementia, for assessing anxiety; Korean Version of Quality of Life-Alzheimer's Disease, for assessing the quality of life. The data were collected from May to June 2008 and analyzed by SPSS/WIN 14.0. Results: 1) The cognitive function of the subjects in the day care center was higher than that of the subjects in the nursing home. Anxiety in the subjects in the nursing home was higher than that in the subjects in the day care center. 2) The cognitive function and quality of life of the subjects in the day care center showed statistically significant correlation, 3) The anxiety and quality of life of the subjects in the nursing home showed statistically significant correlation. Conclusions: Nursing interventions that improve the quality of life of the demented elderly should be considered and applied according to the degree of cognitive function and anxiety.

• Journal of the Korean Society of Food Culture
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• v.35 no.6
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• pp.553-568
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• 2020

This systematic review and meta-analysis aimed to determine whether food intake is effective in preventing diseases related to cognitive impairment. We searched English databases namely MEDLINE, PubMed and ScienceDirect from 2000 to May 2020, and Korean databases namely RISS, KISS, and DBPIA from 1990 to May 2020. We divided the data into 15 groups using the food group classification of the Korean Nutrition Society (KNS). The effect size (Cohen's d) was estimated using a random-effect model, and a 95% confidence interval was calculated for each study. We included 17 cross-sectional studies and 7 cohort studies which involved 45,115 participants. As a result of analyzing the subgroups in the Asian population of both sexes, it was observed that grain intake has a protective effect against cognitive impairment. For females, pulses and fish also have a protective role against cognitive impairment. In the case of seaweed, a negative relationship was found with a moderate protective effect against cognitive impairment (Cohen's d:-0.533, 95% CI: -0.939, -0.126; p=0.010) in Korean studies. Dairy products are associated with an increased risk of cognitive impairment in the American and European population but drinking alcohol is associated with a lower impairment risk. These results provide a basis for formulating the dietary guidelines for preventing dementia for each country.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.6
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• pp.2128-2147
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• 2021

Cognitive radio systems are being implemented recently to tackle spectrum underutilization problems and aid efficient data traffic. Spectrum sensing is the crucial step in cognitive applications in which cognitive user detects the presence of primary user (PU) in a particular channel thereby switching to another channel for continuous transmission. In cognitive radio systems, the capacity to precisely identify the primary user's signal is essential to secondary user so as to use idle licensed spectrum. Based on the inherent capability, a new spectrum sensing technique is proposed in this paper to identify all types of primary user signals in a cognitive radio condition. Hence, a spectrum sensing algorithm using improved convolutional neural network and long short-term memory (CNN-LSTM) is presented. The principle used in our approach is simulated annealing that discovers reasonable number of neurons for each layer of a completely associated deep neural network to tackle the streamlining issue. The probability of detection is considered as the determining parameter to find the efficiency of the proposed algorithm. Experiments are carried under different signal to noise ratio to indicate better performance of the proposed algorithm. The PU signal will have an associated modulation format and hence identifying the presence of a modulation format itself establishes the presence of PU signal.

• Journal of Science Education
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• v.37 no.1
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• pp.142-156
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• 2013

The purpose of this study was to analyze observation characteristics through eye movement according to cognitive style. For this, developed observation task that can be shown the difference between wholistic cognitive style group and analytic cognitive style group, measured eye movement of university students who has different cognitive style, as given observation task. It is confirmed the difference between two cognitive style groups by analysing gathered statistics and visualization data. The findings of this study were as follows; First, Compared observation sequence and pattern by cognitive style, analytic cognitive style group is concerned with spider first and moving on surrounding environment, whereas wholistic cognitive style group had not fixed pattern as observing spider itself and surrounding area of spider alternately or looking closely on particular part at first. When observing entire feature and partial feature, wholistic cognitive style group was moving on Fixation from outstanding factor without fixed pattern, analytic cognitive style had certain directivity and repetitive investigation. Second, compared the ratio of observation, analytic cognitive style group gave a large part to spider the very thing, wholistic cognitive style group gave weight to surrounding area of spider, and analytic group shown higher concentration on observing partial feature, wholistic cognitive style group shown higher concentration on observing wholistic feature. Wholistic cognitive style group gave importance to partial features in surrounding area, and wholistic feature of spider than analytic cognitive style group, analytic cognitive style group was focus on partial features of spider than wholistic cognitive style group. Through the result of this study, there are differences of observing time, frequency, object, area, sequence, pattern and ratio from cognitive styles. It is shown the reason why each student has varied outcome, from the difference of information following their cognitive style, and the result of this study help to figure out and give direction to what observation fulfillment is suitable for each student.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.6
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• pp.677-687
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• 2008

CR technology is an intelligent technology which can sense the spectrum environment an adaptively adjust the parameters for wireless transmission. In this paper, by using CR-UWB, the spectrum efficiency of the transmission channel is largely improved; Furthermore, the interference to other system can be effectively avoided. In this paper, we propose a solution on interference problem of UWB system using cognitive radio. We use interference temperature model of cognitive radio that has proposed by FCC for estimating interference signal. Calculating channel capacity of UWB system with interference temperature, we suggest how to solve interference problem. We have used genetic algorithm in cognitive engine's calculation precess. The proposed UWB System with cognitive radio shows very efficient in solving interference problem.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.4
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• pp.505-512
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• 2013

PURPOSE: The purpose of this study applied computerized cognitive therapy and proprioception exercise to stroke patients and analyzed improvement in their changes in Electrocephalogram(EEG). METHODS: The subjects were 30 patients who were diagnosed with stroke and they were randomly selected to a proprioceptive training group(n=15), a cognitive training group(n=15). The experiment was performed for three times per week for 6 weeks and EEG was measured before and after the experiment. RESULT: Before and after the experiment in each group of experiments, the ${\alpha}$-and ${\beta}$-wave study showed significant changes but, there was no significant difference in the change between groups before and after the experiment. CONCLUSION: From the above results, the cognitive training and the proprioception training have a positive impact in stroke patients EEG changes, but it is difficult to suggest a better therapeutic interventions. However, as compared with that the cognitive training that directly involved in the cognitive and brain activation, the proprioception training have changes on brain activation. Therefore, of Clinical therapeutic interventions, the proprioception training can be presented effectively to the changes in brain activation in stroke patients.