• Title/Summary/Keyword: Coefficient of Determinant

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Quantitative Ultrasound Radiofrequency Data Analysis for the Assessment of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Using Magnetic Resonance Imaging Proton Density Fat Fraction as the Reference Standard

  • Sun Kyung Jeon;Jeong Min Lee;Ijin Joo;Sae-Jin Park
    • Korean Journal of Radiology
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    • v.22 no.7
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    • pp.1077-1086
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    • 2021
  • Objective: To investigate the diagnostic performance of quantitative ultrasound (US) parameters for the assessment of hepatic steatosis in patients with nonalcoholic fatty liver disease (NAFLD) using magnetic resonance imaging proton density fat fraction (MRI-PDFF) as the reference standard. Materials and Methods: In this single-center prospective study, 120 patients with clinically suspected NAFLD were enrolled between March 2019 and January 2020. The participants underwent US examination for radiofrequency (RF) data acquisition and chemical shift-encoded liver MRI for PDFF measurement. Using the RF data analysis, the attenuation coefficient (AC) based on tissue attenuation imaging (TAI) (AC-TAI) and scatter-distribution coefficient (SC) based on tissue scatter-distribution imaging (TSI) (SC-TSI) were measured. The correlations between the quantitative US parameters (AC and SC) and MRI-PDFF were evaluated using Pearson correlation coefficients. The diagnostic performance of AC-TAI and SC-TSI for detecting hepatic fat contents of ≥ 5% (MRI-PDFF ≥ 5%) and ≥ 10% (MRI-PDFF ≥ 10%) were assessed using receiver operating characteristic (ROC) analysis. The significant clinical or imaging factors associated with AC and SC were analyzed using linear regression analysis. Results: The participants were classified based on MRI-PDFF: < 5% (n = 38), 5-10% (n = 23), and ≥ 10% (n = 59). AC-TAI and SC-TSI were significantly correlated with MRI-PDFF (r = 0.659 and 0.727, p < 0.001 for both). For detecting hepatic fat contents of ≥ 5% and ≥ 10%, the areas under the ROC curves of AC-TAI were 0.861 (95% confidence interval [CI]: 0.786-0.918) and 0.835 (95% CI: 0.757-0.897), and those of SC-TSI were 0.964 (95% CI: 0.913-0.989) and 0.935 (95% CI: 0.875-0.972), respectively. Multivariable linear regression analysis showed that MRI-PDFF was an independent determinant of AC-TAI and SC-TSI. Conclusion: AC-TAI and SC-TSI derived from quantitative US RF data analysis yielded a good correlation with MRI-PDFF and provided good performance for detecting hepatic steatosis and assessing its severity in NAFLD.

Evaluation on Kinematic Factors Affecting Scores of Olympic Round Game during the Follow Through in Archery (양궁 올림픽 라운드기록에 영향을 미치는 팔로 드로우 국면의 운동학적 요인 평가)

  • Hah, Chong-Ku;Yi, Jae-Hun
    • Korean Journal of Applied Biomechanics
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    • v.18 no.1
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    • pp.227-234
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    • 2008
  • The purpose of this study was to investigate kinematic factors affecting scores of Olympic Round Game during follow through which was basic and important in archery. For this study, 8 male archers($20{\pm}1\;yrs$, $77{\pm}13kg$, $178{\pm}5\;cm$) of K university participated in the experiment. The seven infrared cameras (Qualisys MCU-240) were used to acquire raw data, and analyzed with Matlab6.5 for variables. The results were as follows: First, angular average velocity of shoulder joint affecting scores was a statistical significance (p=.65, p<.10), and the regression equation was y = - 0.0637 x + 17.074, and determinant coefficient $R^2$ = 0.874 respectively. Second, good records was acquired about $120^{\circ}$/sec. of angular average velocity of shoulder joint. Third, as records was lower and lower, a peak-pulse on angular average velocity of shoulder joint was great during follow through. In conclusion, the record was greater as angular average velocity of shoulder joint was smaller and smaller from $110^{\circ}$/sec. to $160^{\circ}$/sec. It is suggested that a lower angular average velocity of shoulder joint and no peak-pulse may obtain good scores during follow through.

Correlation between Measured Resting Energy Expenditure and Predicted Basal Energy Expenditure in Female College Students (여대생을 대상으로 한 실측 휴식대사량과 예측 기초대사량의 상관관계에 관한 연구)

  • Chang, Un-Jae;Lee, Kyeong-Ryeong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.2
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    • pp.196-201
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    • 2005
  • The aim of this study was to confirm the validity of predictive equations for the calculation of basal energy expenditure (BEE). One hundred twenty female college students were participated in this study. The resting energy expenditure (REE) was measured by indirect calorimetry for 30 minutes following an 12 hour overnight fasting. Among the available equations for predict BEE, Harris-Benedict, WHO/FAO/UNU and Cunningham methods were selected. Body composition was estimated by bioelectrical impedance analysis (BIA) for the equation of predicted BEE. The mean of measured REE was 1257.2$\pm$147.9 kcal/day, while the predicted value by Harris-Benedict, WHO/FAO/UNU and Cunningham were 1373.3$\pm$45.4 kcal/day, 1290.0$\pm$61.7 kcal/day and 1187.6$\pm$49.2 kcal/day, respectively. The Cunningham equation was more closed to measured values than Harris-Benedict and WHO/FAO/UNU equation by the correlation coefficient. Comparing Pearson's correlation coefficients, fat-free mass (FFM), body surface area (BSA) and body weight were higher than others such as height, body mass index (BMI), fat and fat%. The FFM's correlation coefficient was the highest as 0.74. Thus, the conclusion of this study suggested that the main determinant of BEE was FFM, and we derived a prediction equation as follows: BEE=-569.86+48.27 (FFM).

Studies on Determinant Factors of SCM Performance: From the Supplier Perspective (SCM 성과 결정요인에 관한 통합적 연구: 공급업체 관점으로)

  • Park, Kwang-Oh;Chang, Hwal-Sik
    • Asia pacific journal of information systems
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    • v.21 no.1
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    • pp.1-27
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    • 2011
  • In an attempt to cope with widespread, dynamic, and accelerating changes in both internal and external business environments, companies often utilize information technologies such as SCM(Supply Chain Management). To date, SCM research has mainly focused on the effects of dynamic factors on SCM success and emphasized adoption strategies and critical success factors. Consequently, the effects of more static factors such as interdependency between SCM partners have been largely ignored. The purpose of this study, therefore, is to examine the effects of both dynamic and static factors on SCM performance by controlling for information quality and partnership quality. The five factors examined in this study include innovative ness, mutual dependency, quality of information, partnership quality, and SCM performance. All factors were examined from the perspective of part suppliers, except the mutual dependency which was examined from two aspects: supplier's dependency on customer and customer's dependency on supplier. Data was collected through five hundred survey questionnaires distributed to the part supplier companies that have implemented SCM systems for at least one year. As a result, a total of 170 valid responses were obtained. A structural equation research model was fitted using SAS 9.1.3 and SMART-PLS 2.0. The results of this study can be summarized as follows. First, innovativeness positively affected SCM information quality. SCM partnership quality, and ultimately SCM performance. The path coefficient between innovativeness and information quality was 0.387, with a t-value of 3.528. Innovativeness also had a positively direct effect on partnership quality. The path coefficient was 0.351 with a t-value of 3.366. The total effect of innovativeness on partnership quality was significant, although its indirect effect on partnership quality by altering information quality was negligible. The total indirect effect of innovativeness on SCM performance by affecting information quality and partnership quality was significant with a p-value of 0.014. Innovativeness played an important role in determining SCM performance. Second, mutual dependency showed no significant effect on SCM information quality. This result contradicts the earlier assertion that the more dependent two companies are, the more accurate and timely the information they exchange ought to be. This study showed that this may not be the case; a partner may provide information of poor quality even when it is strongly dependent on the other. Mutual dependency showed significant effect on partnership quality. However, when the mutual dependency perceived by suppliers was divided into two parts, one being a supplier's dependency on its customer company and the other being a customer's dependency on the supplier, the latter showed a significant impact on the perceived SCM partnership quality. This result indicates that a customer company can hardly improve the partnership quality perceived by suppliers by making them more dependent. It improves only when the suppliers perceive that their partners, typically having more bargaining power, are more dependent on them. The overall effect of mutual dependency of any kind on SCM performance, however, was not significant. Although mutual dependency has been mentioned as an important static factor influencing almost every aspect of cooperation on a supply chain, its influences may not be as significant as it was initially perceived to be. Third, the correlation between information quality and partnership quality was 0.448 with a p-value of less than 0.001. Information quality had a path coefficient of 0.256 to partnership quality with a t-value of 2.940. The quality of information exchanged between partners may have an impact on their partnership quality. Fourth, information quality also had a significant impact on SCM performance with a path coefficient of 0.325 with a t-value of 3.611. In this study, SCM performance was divided into four categories: product quality, cost saving, service quality, and order fulfillment. Information quality has Significant impacts on product quality, cost saving and service quality, but not on order fulfillment. Fifth, partnership quality, as expected, had a significant impact on SCM performance. The path coefficient was 0.403 with a t-value of 3.539. Partnership quality, like information quality, had positive impacts on product quality, cost saving and service quality, but showed no impact on order fulfillment. It seemed that order fulfillment is the hardest category of performance that SCM can satisfy. One major limitation of this study is that it surveyed only the suppliers. To better understand the dual aspects of SCM, it is important to survey both suppliers and the assemblers, especially in pairs. This research, to our best knowledge, was the first attempt to study the level of dependency between the two groups by measuring the dual aspects of SCM and studying mutual dependency from the categories of suppliers and assemblers each.. In the future, a more comprehensive and precise measurement of SCM characteristics needs to be achieved by examining from both the supplier's and assembler's perspectives.

Processing Optimization and Physicochemical Characteristics of Collagen from Scales of Yellowfin Tuna (Thunnus albacares)

  • Han, Yuna;Ahn, Ju-Ryun;Woo, Jin-Wook;Jung, Cheol-Kyun;Cho, Sueng-Mock;Lee, Yang-Bong;Kim, Seon-Bong
    • Fisheries and Aquatic Sciences
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    • v.13 no.2
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    • pp.102-111
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    • 2010
  • This study was conducted to investigate the optimal conditions of collagen extraction from scales of yellowfin tuna (Thunnus albacares) using surface response methodology. Four independent variables of NaOH concentration and pretreatment fime in alkali pretreatment and enzyme concentration and treatment time in enzyme hydrolysis were used to predict a model equation for the collagen yield. The determinant coefficient ($R^2$) for the equation was 0.906. The values of the independent variables for the maximum yield were 0.32 N NaOH, 16.38 h alkali pretreatment time, 0.18% enzyme concentration, and 31.02 h enzyme treatment time. In the physicochemical properties of tuna scale collagen, sodium dodecyl sulfate-polyacrylamide gel electrophoresis of tuna scale collagen showed the same migration distances as that of calf skin collagen. The amide A, I, II, and III regions of tuna scale collagen in Fourier transform infrared measurements were shown in the peaks of 3,414 $cm^{-1}$, 1,645 $cm^{-1}$, 1,553 $cm^{-1}$, and 1,247 $cm^{-1}$, respectively. The amount of imino acids in tuna scale collagen was 18.97% and the collagen denaturation temperature was $33^{\circ}C$. The collagen solubility as a function of NaCl concentration decreased to 4% NaCl (w/v) and the collagen solubility as a function of pH was high at pH 2-4 and sharply decreased from pH 4 to pH 7. Viscosity of the collagen solution decreased continuously until $30^{\circ}C$ and this decreasing rate slowed in the temperature range of $35-50^{\circ}C$.

A Study on Hypertensive Patients Compliance to Medical Recommendations (고혈압 환자의 치료지시 이행에 관한 연구)

  • 최영희
    • Journal of Korean Academy of Nursing
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    • v.10 no.2
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    • pp.73-85
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    • 1980
  • The purpose of this study was to investigate the compliance behavior of hypertensive patients in light of their health belief model that explains an individual's compliance with health maintenance or getting well. Although there are many effective regimens and treatments for hypertension nowadays. the most important point to be taken to consideration in their behavioral aspect is their compliance with regard to the control of body weight. eating habits as to salt and cholesterol intake. stresses. activity patterns and smoking as related to their life style. The important reasons for the failure in the control of hypertensive patients are the complexity of regimens to be complied to. irregular medication and the life long restrictions in their own life style. The compliance of patients to medical regimens and rocommendations or failure to do so is an essential factor. Accordingly. the degree of the patient's compliance is an important determinant as to the success or failure of hypertension control. The subjects for this study were 187 hypertensive patients selected from admitted and out patients of the medical department at seven University Hospitals in Seoul. Data was collected from Dec. 1, 1979 to Feb. 15, 1980 using the questionaire method and was analysed by the use of means. standard deviations, coefficient of correlations, analysis of variance and multiple regression analysis. The results obtained are as follows A. Of the seven independent variables in light of health belief model. benefit. barrier and severity are closely related to patient's compliance behavior. Therefore these variables could be used as determinants to predict and modify the hypertensive behavior. 1. Benefit is the most important and significant of the variables for explaining the dependent variables. It accounts for the highest variance of patient's compliance. (23.62%) 2. Then taking the former together with barrier. the variance of compliance showed on increase. (26.59%) 3. And with the addition of severity to the first two. the variance of compliance was also increased. (28.l2 %) B. Except for susceptibility all the independent variables such as severity. benefit, knowledge. motivation and barrier are correlated to dependent variable compliance. C. Sex. marital status and religion appeared to have significant influence on the dependent variables. Therefore one could conclude that the more the patients are aware that hypertension is a threat to health. the more they understand the benefit of taking actions to prevent such a threat. and the less they perceive any barrier when taking action. the more compliant they become in following medical regimens and recommendations. Age. marital status and religion played a significant influence to their compliance. Accordingly. the selected structural variables and demographic variables which have influenced sick role behavior of the hypertensive patient must be integrated to teaching and counselling programs for better hypertension control.

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Some Factors Affecting Bone Mineral Density of Korean Rural Women (농촌 성인 여성들의 골밀도에 영향을 미치는 요인 분석 연구)

  • 이정숙
    • Journal of Nutrition and Health
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    • v.32 no.8
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    • pp.935-945
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    • 1999
  • The factors affecting bone mineral density (BMD) of 103 rural women aged 30 to 76 years were investigated. Data for food and nutrient intake was obtained by 24-hour recall method. BMD of lumbar spine(L1-L4), femoral neck, ward's triangle and trochanter was measured by XR-series x-ray bone densitometer. Serum was collected and analyzed for total Ca, P and ionized Ca (Ca++)content. Relationship between the factors and BMDs was analyzed by Pearson's correlation coefficient(r) and multiple regression analysis. The results are summarized as follows. 50% of the subjects under 50 years of age($\leq$49 yr group) and 86.4% of the subjects from 50 up($\geq$50yr group) were classified as osteopenia or osteoporosis. Mean body weight, height and BMI were 153.1cm, 59.1kg and 25.0kg/$m^2$ in $\leq$49 yr group and 151.9cm, 55.9kg, and 24.2kg/$m^2$ in $\geq$50 yr group. BMDs of lumbar spines and femurs ranged from 0.84 to 1.05g/$m^2$ and from 0.67 to 1.16g/$m^2$ in $\leq$49 yr group, and ranged from 0.67 to 0.85kg/$m^2$ and from 0.68 to 0.44g/$m^2$ in $\geq$50 yr group, respectively. On the whole, the BMDs were reduced to 83.8 to 94.2% of peck bone mass in $\leq$49 yr group and 55.2 to 78.9% of those in $\geq$50 yr group. Mean daily intake of Ca was much less than the Korean RDA, \67.2% in $\leq$49 yr group and 62.3% in $\geq$50 yr group. The average concentration of total Ca, P and Ca++ in serum were within normal range in both age group. Both age and height were significantly related with BMD in both age group but the relationship tended to be stronger in $\geq$50 yr group than in $\leq$49 yr group. Body weight was also a potent determinant of BMD only in 50 yr group. In $\leq$49 yr group, total food intake was positively related with BMDs of ward's triangle, L1 and L2 and intake of cereals and grain products, sugars and sweets, milk and dairy products was positively related with BMDs measured in this study. On the contrary, intake of eggs, oil and fats were positively related with a few BMDs in 50 yr group. The BMDs were positively affected by intake of energy, protein, carbohydrate, Ca, P and Fe in $\leq$49 yr group and those of protein, fat Ca, P, vitamin B1, vitamin B2 and vitamin C in $\geq$50 yr group. It was noteworthy that serum Ca++ concentration was positively related with BMDs of lumbar spine in boty age groups. According to multiple regression analysis, the four factors, age, body weight, height and BMI additionally accounted for 21% of the variance in BMD of trochanter in $\leq$49 yr group and only two factors, age and C a intake accounted for 38% of that of femoral neck in $\geq$50 yr group. Further investigation is necessary to make sure of the relations between BMD and serum Ca++ level.

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Shear Wave Velocity Estimation of Railway Roadbed Using Dynamic Cone Penetration Index (동적 콘 관입지수를 이용한 철도노반의 전단파속도 추정)

  • Hong, Won-Taek;Byun, Yong-Hoon;Choi, Chan Yong;Lee, Jong-Sub
    • Journal of the Korean Geotechnical Society
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    • v.31 no.11
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    • pp.25-31
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    • 2015
  • Elastic behavior of the railway roadbed which supports the repeating dynamic loads of the train is mainly affected by the shear modulus of the upper roadbed. Therefore, shear wave velocity estimation of the uniformly compacted roadbed can be used to estimate the elastic behavior of the railway roadbed. The objective of this study is to suggest the relationship between the dynamic cone penetration index (DCPI) and the shear wave velocity ($V_s$) of the upper roadbed in order to estimate the shear wave velocity by using the dynamic cone penetration test (DCPT). To ensure the reliability of the relationship, the dynamic cone penetration test and the measurement of the shear wave velocity are conducted on the constructed upper roadbed. As a method for measurement of the shear wave velocity, cross hole is used and then the dynamic cone penetration test is performed at a center point between the source and the receiver of the cross hole. As a result of the correlation of the dynamic cone penetration index and the shear wave velocity at the same depths, the shear wave velocity is estimated as a form of involution of the dynamic cone penetration index with a determinant coefficient above 0.8. The result of this study can be used to estimate both the shear wave velocity and the strength of the railway roadbed using the dynamic cone penetrometer.

Determinant Factor Analysis for the Spread of Water Reuse (물재이용 활성화를 위한 결정요인분석)

  • Park, Hyunju;Kim, Tschungil;Han, Mooyoung
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.4
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    • pp.271-276
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    • 2014
  • The purpose of this study was to survey Suwon citizens over the age of 20 in order to provide basic data on the extent of coverage of the city's water reclamation system and to set guidelines for a policy on water reuse. The survey used a questionnaire with two fields, rainwater use and wastewater recycling, for analyzing factors that influenced water reuse. A factor analysis of 19 questionnaires gave a Cronbach's alpha coefficient greater than 0.4. Factors that influenced rainwater use were environmental protection, water charges, and the risk of climate change. Of the total explanatory power, the share of rainwater use and environmental protection was 39.7% and 28.1% respectively. Environmental protection (explanatory power 24.2%) had an effect on the explanatory power of wastewater reuse. When factors influencing wastewater recycling, like cost of recycling, water management policy, climate change, and suspension of tap water supply were included, the explanatory power of each of these factors went up by 4.3%, 2.8%, 3.3%, and 1.1%, respectively. For more effective wastewater recycling, a water management policy that factors in the above is required, along with a campaign to educate citizens on water management and environment conservation. Additionally, it may be necessary to improve the reliability and the quality of water supply.

Evaluation of various cephalometric measurements to predict the prognosis of early Class III malocclusion treatment (III급 부정교합의 조기 치료 예후 예측를 위한 두부방사선 계측 변수의 평가)

  • Son, Myung-Ho;Chang, Young-Il
    • The korean journal of orthodontics
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    • v.34 no.3 s.104
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    • pp.205-218
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    • 2004
  • The aims of this study were to investigate the differences in the early craniofacial morphology of Class III malocclusions with good, fair and poor occlusal stability and to elucidate a key determinant for distinguishing the cases. Lateral cephalograms of 30 subjects with Class III malocclusion in the mixed dentition were analyzed at the start of treatment (mean age of $8.58\pm1.47$). All subjects were reevaluated after a mean period of $7.50\pm1.94$ years comprising active treatment and retention. At this time, the samples were divided into three groups: good (10 subjects), fair (10 subjects) and poor (10 subjects) occlusal stability groups. According to the results of ANOVA, there were significant morphological differences in the early stage among the good, fair and poor occlusat stability groups, especially in variables that represented the vertical skeletal relationships. As well, there were already more dental compensations in the poor occlusal stability group. Stepwise discriminant analysis on the measurements at the time of first observation identified only one predictive variable: AB to mandibular plane angle(AB-MP). With this discriminant function, $83.3\%$of the original grouped cases were correctly classified and the canonical correlation coefficient was 0.857. In conclusion, AB-MP can be a possible predictor for the eventual prognosis of early Class III treatment. If it is below 60, the prognosis of early Class III treatment is expected to be poor, while if it is above 65, a good prognosis is expected.