• Title/Summary/Keyword: Cochrane Risk of Bias

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Safety and Efficacy of Low Level Laser for Alopecia : A Systematic Review (탈모에 대한 레이저의 안전성 및 유효성 : 체계적 문헌 고찰)

  • Lee, Bo-Ram;Lee, Ma-Eum;Ko, Kyoung-Sook;Seo, Hyung-Sik
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.4
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    • pp.90-100
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    • 2019
  • Objectives : The purpose of this study is to determine the safety and efficacy of low level laser. Methods : We searched 11 electronic databases(Pubmed, CAJ, EMBASE, Medline, Cochrane Library, KMBASE, KISS, KISTI, NDSL, RISS, Oasis) up to March 2019. We included randomized controlled trials(RCTs) using low level laser for alopecia. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results : 8 RCT studies were eligible in our review. The meta-analysis of 2 studies showed favorable results for the use of low level laser with minoxidil 5% than minoxidil 5% and 6 studies showed favorable results for the use of low level laser than placebo light. The results of meta-analysis showed that low-level laser has an efficacy on alopecia. There were no serious side effects or adverse effects. High risk of bias were observed in all studies. Conclusion : Now limited evidence is available to support low level laser for alopecia and further well-designed RCTs should be encouraged.

Baduanjin for Hypertension : Systematic Review (팔단금 도인 운동이 고혈압에 미치는 영향 : 체계적 문헌 고찰)

  • Cho, Hyung-Joon;Bae, Dong-Ryeol;Kim, Hee-Na;Hwang, Eui-Hyoung
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.12 no.1
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    • pp.43-56
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    • 2017
  • Objectives : To determine the effectiveness of Baduanjin for hypertension Methods : We searched 8 electronic databases(Pubmed, CAJ, EMBASE, Cochrane Library, KISS, KISTI, NDSL, RISS) up to April 2017. We included randomized controlled trials(RCTs) using Badanjin for hypertension. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results : 14 RCT studies were eligible in our review. 14 studies were divided into 4 groups, and 2 of them were meta-analysised. The meta-analysis of 10 studies showed favorable results for the use of Baduanjin with Usual care than Usual care. But, meta-analysis of 2 studies showed Baduanjin and Usual care has no difference. High risk of bias were observed in all studies. Conclusions : Although there are favorable results with meta-analysis, our systematic review are highly dependent on the single source of Chinese electrical database, CAJ. Now limited evidence is available to support Baduanjin combined usual care for hypertension and further well-designed RCTs should be encouraged.

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Tai-chi for Low back pain: Systematic Review (태극권 운동이 요통에 미치는 영향 : 체계적 문헌 고찰)

  • Choo, Su-Cheol;Kim, Kyu-Jin;Kim, Eun-Bi;Hwang, Eui-Hyoung
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.13 no.1
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    • pp.35-44
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    • 2018
  • Objectives: To determine the effectiveness of Tai-chi in treatinglow back pain. Methods: We searched 9 electronic databases(Pubmed, CAJ, EMBASE, Cochrane Library, Web of Science, KISS, KISTI, NDSL, and RISS) till April 2018 and included randomized controlled trials(RCTs) that used Tai-chi for lower back pain treatment. The methodological quality of each RCT was assessed usingthe Cochrane risk of bias tool. Results: As per the inclusion criteria, 5 RCTswere found to be eligible for our review. These studies were divided into 4 groups and meta-analysis was performed. The meta-analysis of 1 study showed favorable results regardingthe use of Tai-chi. Twostudies showed favorable results regardingthe use of Tai-chi with Tuina rather than Tuina alone. All studies were observed to have a high risk of bias. Conclusions: There is limited evidence available to support the effectiveness of Tai-chi in relieving low back pain;hence, additionalwell-designed RCTs should be encouraged for better evidence.

Review of Chuna Manual Therapy for Adult Digestive System Disease (추나 치료가 성인 소화기계 질환에 미치는 영향에 대한 문헌 고찰)

  • Kim, Kyu-Jin;Choo, Su-Cheol;Lee, Jae-Won;Hwang, Eui-Hyoung
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.13 no.2
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    • pp.35-46
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    • 2018
  • Objectives : To determine the effectiveness of Chuna manual therapy(CMT) for Adult Visceral Diseases. Methods : To find evidence of CMT for adult digestive system disease, we used 9 electronic databases(Pubmed, CAJ, EMBASE, Cochrane Library, Web of Science, KISS, KISTI, NDSL, RISS) up to April 2018. We reviewed randomized control trials(RCTs) using Chuna for Digestive system disease. To assess the methodological quality of each RCT, we used the Cochrane risk of bias tool. Results : We identified 11 RCTs about irritable bowel syndrome, chronic ulcerative colitis, gastritis, gastroptosis, spleen entropathy, gastrointestinal dysfunction after stroke in 356 studies. All studies used total efficiency rate for main outcome. In all studies, CMT was effective for digestive system disease. Conclusions : CMT was effective for Digestive system disease. Risk of bias was high and the difference between the experimental group and the control group was not great. Considering that there were no reports of side effects, it seems possible to apply CMT to the treatment of adult digestive system disease.

The Efficacy of Acupuncture on Postpartum Urinary Incontinence: A Systemic Review and Meta-analysis (산후 요실금에 대한 침의 효과 : 체계적 문헌고찰 및 메타분석)

  • Lee, Soo-Hyung;Kim, Song-Baek
    • The Journal of Korean Obstetrics and Gynecology
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    • v.35 no.3
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    • pp.37-55
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    • 2022
  • Objectives: The purpose of this study is to investigate the efficacy and safety of acupuncture on postpartum urinary incontinence. Methods: 'postpartum urinary incontinence', 'postnatal urinary incontinence', 'acupuncture' were searched on 4 online databases (Cochrane Library, Pubmed, CNKI, OASIS). Randomized controlled trials (RCTs) that used acupuncture on postpartum urinary incontinence were included. The methodological quality of each RCT was assessed by using Cochrane risk of bias tool. Results: 12 RCTs were finally selected. The overall risk of bias was evaluated as uncertain. 11 studies showed that combined treatment group was better than control group in effective rate and/or ICIQ-SF total score, but among those 1 study was not statistically significant in ICIQ-SF total score. In the comparison of alone treatment group and control group, 1 study showed favorable effect in ICIQ-SF total score, but 1 study was not significant in effective rate. Conclusions: Treatment that include acupuncture can effect on postpartum urinary incontinence. but considering quality of studies, inconsistent and insufficient evidence, further well-designed studies are needed to confirm the efficacy and safety of this treatment.

Chuna Manual Therapy for Temporomandibular Joint Disorder: Systematic Review (추나요법이 턱관절 증후군에 미치는 영향: 체계적 문헌 고찰)

  • Bae, Dong-Ryeol;Cho, Hyung-Joon;Kim, Hee-Na;Hwang, Eui-Hyoung
    • Journal of Korean Medicine Rehabilitation
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    • v.27 no.3
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    • pp.71-79
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    • 2017
  • Objectives To determine the effectiveness of Tuina for temporomandibular joint disorder. Methods We searched 10 electronic databases (Pubmed, CNKI, EMBASE, Cochrane Library, KISS, KISTI, NDSL, RISS, KMBASE, DBpia) up to May 2017. We included randomized controlled trials (RCTs) using Tuina for temporomandibular joint disorder. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results 14 RCT studies were eligible in our review. 14 studies were divided into 4 groups, and meta-analysised. The meta-analysis of 6 studies showed favorable results for the use of Tuina. High risk of bias were observed in 9 studies. Conclusions Although there are favorable results with meta-analysis, our systematic review are highly dependent on the single source of Chinese electrical database, CNKI. Now limited evidence is available to support Tuina for temporomandibular joint disorder and further well-designed RCTs should be encouraged.

Effects of Nature-Based Programs for Workers in Korea: A Systematic Review

  • Shin, Jong-Yeon;Shin, Won-Sop
    • Journal of People, Plants, and Environment
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    • v.23 no.2
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    • pp.125-138
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    • 2020
  • The aim of this study was to review previous literature to determine the effects of nature-based program for workers. This systematic review was conducted in accordance with National Evidence-based Healthcare Collaborating Agency's guidance for undertaking systematic reviews for intervention. Literature search was performed using National Assembly Digital Library, Korean Studies Information Service System, and Korea Education & Research Information Service for literature published until March 2019. The participants were full-time workers, and intervention of nature-based programs was conducted in the outdoor, indoor, and indirect nature contact exposures, with comparators in the control group who did not receive the treatment. The results showed that the programs were effective in physical, psychological, and social health. The methodological quality of randomized controlled trials (RCT) was assessed using the Cochrane Risk of Bias(RoB) tool, while non-randomized controlled trials (N-RCT) were assessed using the Cochrane Risk of bias assessment tool for non-randomized studuies (RoBANS). A total of 16 studies were selected for assessment: two RCTs, 10 N-RCTs, and four one-group pretest-posttest designs. Most interventions were provided at the workplace and in the community. There were many kinds of nature-based interventions, and forest therapy and horticultural therapy programs were most common. Various interventions for workers effectively improved job stress, depression, serum cortisol and stress-response. However, the included studies lacked methodological rigor. Future research is needed to evaluate the long-term effectiveness of nature-based programs for workers using rigorous research designs.

The Effect of Sayeok-san for Insomnia: A Systematic Review and Meta-Analysis (사역산(四逆散)의 불면 치료 효과 : 체계적 문헌 고찰 및 메타 분석)

  • Huh, Tae-young;Ha, Da-jung;Kim, Kyoung-min
    • The Journal of Internal Korean Medicine
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    • v.42 no.4
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    • pp.547-562
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    • 2021
  • Objectives: This study evaluated the effectiveness of Sayeok-san for treating insomnia. Methods: We conducted a search using keywords, such as "Sayeoksan", "Si-ni-san", and "insomnia" in eight databases (CNKI, Wanfang, Pubmed, Embase, Cochrane, NDSL, OASIS, RISS) on July 17, 2012. There was no limit placed on the publication period of the papers, and we used Cochrane's risk of bias tool to assess their quality. Meta-analysis was classified according to the outcome measurements, such as total effective rate and PSQI. Results: Nine RCTs were selected. Meta-analysis showed that the treatment group, which used Sayeok-san, had a higher total effective rate than did the control group that used only Western medicine. The treatment group also had a lower average of PSQI and TSS (TCM symptom score) than did the control group. Conclusion: This study suggests that Sayeok-san is effective in treating insomnia. However, these findings should be interpreted cautiously due to unknown or high risk of bias of the included trials.

Application of Traditional East Asian Herbal Medicine for Atrophic Vaginitis: A Systematic Review of Randomized Controlled Trials (위축성 질염에 대한 한약 투약의 효과 : 체계적 문헌 고찰)

  • Park, Eo-Jin;Jo, Hee-Geun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.32 no.3
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    • pp.227-244
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    • 2019
  • Objectives: To evaluate the effectiveness and safety of application of Traditional East Asian Herbal Medicine (TEAM) in the treatment of Atrophic Vaginitis (AV). Methods: Randomized Controlled Trials (RCTs) were obtained from PubMed, Cochrane Library, Embase, CNKI, RISS, NDSL, and KISS. The risk of bias was assessed by using Cochrane's risk of bias tool, and RevMan 5.3 software was used. Results: 26 RCTs with 3,162 patients were identified and reviewed. Among them, 21 RCTs observe the effect of integrated traditional Chinese and Western medicine. 23 RCTs reported treatment groups was statistically effective than control groups in the study. Also, the recurrence rate was estimated in 10 RCTs and was lower than control groups. 12 studies observed adverse events (AEs) and severe AEs were not reported. Conclusions: This review suggested that TEAM was safe and effective in the treatment of AV. TEAM may also decrease the recurrence rate. However, this could not be proven conclusively. To ensure evidence-based clinical practice, well-designed trials with larger sample sizes are needed.

Traditional Herbal Medicine for Dysfunctional Uterine Bleeding versus Western Medicine: A Systematic Review of Randomized Controlled Trials (기능성 자궁출혈에 대한 한약치료 : 체계적 문헌 고찰)

  • Park, Eo-Jin;Jo, Hee-Geun;Choi, Ji-Hyun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.31 no.4
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    • pp.110-127
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    • 2018
  • Objectives: To evaluate the effectiveness and safety of traditional herbal medicine (THM) in the treatment of dysfunctional uterine bleeding (DUB) versus conventional western medicine. Methods: Randomized Controlled Trials (RCTs) comparing THM vs. conventional western medicine for DUB, were obtained from PubMed, Cochrane Library, Embase, CNKI, RISS, NDSL, KISS and OASIS. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 16 RCTs with 1,659 patients were identified and reviewed. 10 RCTs reported THM was statistically effective than control group in effective rate. Also recurrent rate was estimated in 6 RCTs and was lower than control group. 7 studies observed adverse events (AEs) and severe AEs were not reported. Conclusions: Despite several limitations, this review suggested that THM was safe and effective in the treatment of DUB. THM may also decrease the recurrence rate. However, this could not be proven conclusively. To ensure evidence-based clinical practice, more sternly designed trials are warranted.