• 제목/요약/키워드: Cochrane Risk of Bias

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Prevalence of Sarcopenia Among the Elderly in Korea: A Meta-Analysis

  • Choo, Yoo Jin;Chang, Min Cheol
    • Journal of Preventive Medicine and Public Health
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    • 제54권2호
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    • pp.96-102
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    • 2021
  • Objectives: Sarcopenia is a common disease in the elderly population that causes disability, poor quality of life, and a high risk of death. In the current study, we conducted a meta-analysis to report basic knowledge about the prevalence of sarcopenia in the elderly in Korea. Methods: We searched for articles in the MEDLINE, Cochrane Library, Embase, and Scopus databases published until December 28, 2020. Studies investigating the prevalence of sarcopenia in elderly Koreans aged ≥65 years were included. The methodological quality of the studies was evaluated using the Newcastle-Ottawa scale. Publication bias was evaluated using the Egger test and funnel plots. Results: In total, 3 studies and 2922 patients were included in the meta-analysis. All 3 studies used the European Working Group on Sarcopenia in Older People criteria for the diagnosis of sarcopenia. The total prevalence of sarcopenia was 13.1-14.9% in elderly men and 11.4% in elderly women. Conclusions: This meta-analysis is the first to estimate the pooled prevalence of sarcopenia in elderly Koreans, and its findings suggest that sarcopenia is common in this population. Therefore, attention should be paid to the prevention and control of sarcopenia.

소아 뇌성마비에 대한 추나 요법의 효과: 체계적 문헌고찰과 메타분석 (Chuna Manual Therapy for Cerebral Palsy in Children: A Systematic Review and Meta-analysis)

  • 남현서;한승희;안다영;백태현
    • 척추신경추나의학회지
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    • 제16권2호
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    • pp.29-38
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    • 2021
  • Objectives This study was aimed to evaluate the effects of Chuna manual therapy (CMT) for the treatment of cerebral palsy. Methods The randomized controlled trials (RCTs) on the treatment of CMT for cerebral palsy in children were selected among the literature published until January 2021 in seven databases. The quality of the literature was evaluated using the Cochrane's risk of bias tool, and RevMan 5.3 was used for the synthesis of results. Results Total 801 pediatric patient with cerebral palsy incontinence were finally selected from twelve RCTs. The total effective rate of the combined treatment general rehabilitation and CMT is statistically significantly higher (P<0.0001) than that of general rehabilitation alone. Conclusions This study suggests that general rehabilitation combined with CMT for cerebral palsy in children might be more effective in improving symptoms than general rehabilitation alone. As the number and quality of the literature included in the meta-analysis was insufficient, high-quality clinical studies on CMT for cerebral palsy would be required.

간담도 질환에서의 고빌리루빈혈증에 대한 인진호탕의 임상 효과 : 체계적 고찰 (Clinical Effect of Injinho-tang on Hyperbilirubinemia in Hepatobiliary Disorders: A Systematic Review)

  • 박근준;강희경;한창우
    • 대한한방내과학회지
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    • 제43권6호
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    • pp.1149-1161
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    • 2022
  • Purpose: This systematic review was conducted to evaluate the clinical effects of Injinho-tang on hyperbilirubinemia in hepatobiliary disorders. Methods: We searched for randomized controlled clinical trials that had administered Injinho-tang as an intervention in the following medical databases: Public/Publisher MEDLINE (PubMed), Excerpta Medica dataBASE (EMBASE), Cochrane library, Research Information Sharing Service (RISS), ScienceON, Oriental Medicine Advanced Searching Integrated System (OASIS), and China National Knowledge Infrastructure (CNKI). Among the retrieved studies, only trials that met the inclusion criteria were selected, and serum total bilirubin values were extracted and analyzed from the finally selected trials. Results: The serum total bilirubin values of 1,302 patients with various hepatobiliary diseases were synthesized through a meta-analysis, which confirmed a decrease in serum total bilirubin of 21.03 𝜇mol/L (95% CI -29.58~-12.49, p<0.01) in the group administered with Injinho-tang compared with the control group. Conclusions: Injinho-tang is effective in alleviating hyperbilirubinemia in hepatobiliary diseases when administered with conventional treatment. However, the potential risk of bias, high heterogeneity among the included trials, and differences in herbal composition are limitations of the results of this meta-analysis.

Effects of Manual Therapy on Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Eunsang Lee;Hyunjoong Kim
    • Physical Therapy Rehabilitation Science
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    • 제12권1호
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    • pp.12-18
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    • 2023
  • Objective: Chemotherapy is usually given to inhibit cancer progression. It is the most common side effect of chemotherapyinduced peripheral neuropathy (CIPN) after chemotherapy, and its symptoms include pain such as paresthesia, dysesthesia, allodynia, hyperalgesia, and electrical stimulation. Therefore, in this review, randomized controlled trials (RCTs) were combined to analyze the effect qualitatively and quantitatively in order to find out the effect of manual therapy on patients with CIPN through a meta-analysis. Design: A systematic review and meta-analysis Methods: This review conducted a literature search through international databases (CINAHL, Embase, MEDLINE, Web of Science) in December 2022 to synthesize the effect of manual therapy on the symptomatic improvement of CIPN. Qualitative evaluation (risk of bias) and quantitative evaluation using ReVMan provided by the Cochrane Group were expressed as a random effect model and standardized mean difference (SMD). Results: In four RCTs 165 patients with CIPN were evaluated for symptoms of neuropathy. The experimental group consisting of manual therapy and its subcategories showed significant improvement compared to the control group. The results analyzed through the random effects model were SMD=-1.11; 95% confidence interval, -1.97 to -0.24. Conclusions: We came to the conclusion that manual therapy could significantly contribute to improving the symptoms of CIPN, and since it may vary depending on the technique of manual therapy, further studies on manual therapy suitable for neuropathy are needed.

여성 복압성 요실금에 대한 뜸 치료의 효과 : 체계적 문헌 고찰 (The Efficacy of Moxibustion for Female Stress Urinary Incontinence: a Systematic Review)

  • 박혜린;조희근
    • 대한한방부인과학회지
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    • 제33권4호
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    • pp.1-22
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    • 2020
  • Objectives: The purpose of this review is to evaluate the efficacy of moxibustion for stress urinary incontinence (SUI) in women. Methods: For relevant randomized controlled trials (RCTs), we searched the following databases from their inception to September 1, 2020: The Cochrane Library, PubMed, EMBASE, Chinese National Knowledge Infrastructure Database (CNKI), Koreanstudies Information Service System (KISS), Research Information Sharing Service (RISS), and National Digital Science Library (NDSL). The key search terms were 'stress urinary incontinence' and 'moxibustion'. Data extraction and assessment of risk of bias were conducted by two authors independently. Results: A total of 11 RCTs were finally included in this systematic review. In all studies, moxibustion treatment was applied as an adjuvant therapy to the conventional treatment, and the most common conventional treatment was pelvic floor muscle training (PFMT). The treatment group (conventional treatment plus moxibustion) showed statistically more significant effect than the control group (conventional treatment only) in various evaluation indicators including urinary incontinence frequency, 1 hour urine pad test, quality of life, the clinical efficacy rate, and pelvic muscle strength. Conclusions: In this study, we investigated the efficacy of moxibustion as an adjuvant therapy for female SUI patients. Further studies are needed to supplement the safety of moxibustion and the evaluation of moxibustion dose.

측두하악 장애 치료를 위한 수기치료에 대한 체계적 고찰의 프로토콜 (Manual Therapy in the Treatment of Temporomandibular Disorders: A Protocol for a Systematic Review)

  • 김형석;정재영;정석희
    • 한방재활의학과학회지
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    • 제25권4호
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    • pp.41-46
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    • 2015
  • Objectives This systematic review will analyse randomised controlled trials (RCTs) of manual therapy in patients with temporomandibular disorders (TMDs) to evaluate the efficacy of this approach. Methods RCTs will be identified in the following ten databases based on searches starting with their inception: MEDLINE, EMBASE, CENTRAL, four Korean databases as KoreaMed, DBPIA, NDSL, and RISS and three Chinese databases as CNKI, VIP and Wanfang. The quality of these studies will be analysed using the Cochrane risk of bias. A meta-analysis will be conducted, and subgroup analysis will be considered if comparatively large heterogeneity is detected. Conclusions We plan to publish this systematic review in a peer-reviewed journal. Findings from this review may contribute to the treatment process in clinical situations. Trial registration number: PROSPERO 2015: CRD42015024090

소아 유뇨증에 대한 추나요법의 효과: 체계적 문헌고찰과 메타분석 (Chuna Manual Therapy for Pediatric Enuresis: A Systematic Review and Meta-analysis)

  • 김기현;이남우;신병철
    • 척추신경추나의학회지
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    • 제12권2호
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    • pp.15-29
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    • 2017
  • Objectives: To systematically review and evaluate the effectiveness of Chuna manual therapy (CMT) on Pediatric Enuresis. Methods: We searched 12 English, Chinese and Korean databases by using relevant search terms up to October 2017. Every randomized controlled trials (RCTs) of CMT for Pediatric Enuresis were considered for inclusion. The methodological quality of RCTs was assessed by the Cochrane risk of bias tool. Results: Eleven RCTs with 1110 participants were included. The meta-analysis of 11 studies revealed that CMT had statistically significant effects for Pediatric Enuresis compared to other medications in terms of effective rate. Safety issues are minor. Conclusions: This systematic review suggests that CMT may have positive effects on Pediatric Enuresis and safe treatment as a non-pharmacological treatment, but evidence is limited. For a better quality review, more and high-quality RCTs with standardized interventions are needed to offer sufficient evidence on the effects of CMT for Pediatric Enuresis.

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운동요법으로서 태극권이 혈압에 미치는 영향 : 신속 체계적 고찰 (Effect of Tai Chi as Therapeutic Exercise on Blood Pressure : Rapid Systematic Review)

  • 황의형;허광호;이금산
    • 한방재활의학과학회지
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    • 제23권1호
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    • pp.101-113
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    • 2013
  • Objectives : The purpose of this study is to systematically analyze the effect of Tai Chi as therapeutic exercise on depressing blood pressure. Methods : We reviewed articles published in the PubMed, Chinese Academic Journals(CAJ) and five Korean databases. The searching keywords were "Tai chi AND blood pressure" and "Tai chi AND hypertension". We evaluated the quality with Cochrane risk of bias tool. Results : In the 114 articles searched, 7 randomized controlled clinical trials were selected. Yang(楊) style Tai chi, exercising over 30 minutes a time and over three times a week, had an effect on decreasing blood pressure. However, Wu(吳) style Tai chi was not effective in decreasing blood pressure. Conclusions : Usual exercises for hypertension patients should be performed in the form of moderate exercises intensity for 10-26 weeks by 30-60 minute a time, over 3 times a week. The study of Tai Chi on blood pressure needs to follow this criteria in the future.

소아 자폐스펙트럼 장애의 추나 치료에 대한 중의학 임상 연구 고찰 (Review of Traditional Chinese Medicine Clinical Studies on Tuina Treatment of Children's Autism Spectrum Disorder)

  • 박젬마
    • 대한한방소아과학회지
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    • 제35권3호
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    • pp.28-42
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    • 2021
  • Objectives The purpose of this study is to investigate the effect of Tuina treatment for children with Autism Spectrum Disorder (ASD), and to propose guidance to future studies or application in clinical setting. Methods The articles published from year 2000 to May 2021 by China National Knowledge Infrastructure (CNKI) were searched by setting up field as '中醫學', '中藥', '中西醫結合' and by setting up keyword as '小儿自閉症', '儿童自閉症', '自閉症譜系障碍', 'Autism', 'Autism spectrum disorder' that corresponds to participant and '推拿', '導引', '按摩', 'Tuina', 'massage'. Results Nine selected articles were analyzed and summarized by authors and year published, characteristics, diagnostic criteria, treatment methods and contents, treatment duration, evaluation criteria and results of the study. The articles were also reviewed by reported side effects, and evaluated the quality of the study according to Cochrane Handbook's Risk of Bias 2 (RoB 2) assessment of the Randomized Control Trial (RCT) articles. All studies used Tuina treatment to achieve effective results for pediatric autism spectrum disorder. Conclusion Pediatric Tuina treatment (TM) is a non-invasive treatment that does not stimulate patients with unstable ASD but increase patient adherence, and can be safely and simply operated. Therefore, pediatric Tuina treatment is worth utilizing as a clinical basis for further development of ASD treatment.

인터넷 기반 교육 중재가 산욕기 어머니 건강에 미치는 영향에 대한 체계적 고찰 (Maternal Health Effects of Internet-Based Education Interventions during the Postpartum Period: A Systematic Review)

  • 채정미;김현경
    • 지역사회간호학회지
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    • 제32권1호
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    • pp.116-129
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    • 2021
  • Purpose: This study aimed to investigate the maternal health effects of internet-based education interventions on parturients during the postpartum period through a systematic review of randomized controlled trials. Methods: An electronic literature search of the Cochrane Library, CINAHL, EMBASE, Eric, PsycINFO, PubMed, RISS, and KISS databases was performed, using the combination of keywords such as 'parenthood education', '*natal education', '*birth intervention', 'internet-based intervention', 'randomized controlled trial'. The inclusion criteria were peer-reviewed papers in English regarding randomized controlled trials of internet-based postnatal education interventions. Educational interventions were delivered through any web, mobile, eHealth, mHealth, virtual reality, short message service, or social networking service platform. Quality appraisal was performed using the Risk of Bias 2 (RoB 2) for randomized controlled trials. Nine articles were yielded, and the intervention effects were analyzed. Results: Internet-based education interventions during the postpartum period affect maternal self-efficacy, postpartum depression, and successive breastfeeding; however, they do not affect maternal satisfaction and parenting confidence. Conclusion: This study demonstrated that internet-based education interventions affect maternal health status in terms of psychological, emotional, and physical wellness. Therefore, maternal health care professionals can utilize remote education using the internet or mobile-based interventions during the postpartum period.