• Title/Summary/Keyword: Coagulation test

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Clinical Significance of Coagulation Screening Tests and Platelet Counts in Children Undergoing Endoscopy (소아에서 내시경 검사의 출혈 위험 예측 인자로서 혈액 응고 검사 및 혈소판 검사의 의의)

  • Lee, Eun-Hye;Yang, Hye-Ran;Ko, Jae-Sung;Seo, Jeong-Kee
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.13 no.1
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    • pp.23-29
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    • 2010
  • Purpose: The aim of this study was to assess the benefits of routine pre-endoscopy coagulation screening tests and platelet counts in Korean children. Methods: Between March 2004 and December 2009, children who underwent gastrointestinal endoscopy for the evaluation of various gastrointestinal symptoms were included. All of the subjects included in the study also underwent routine coagulation screening and platelet count determinations prior to endoscopy and biopsy. The clinical records and laboratory tests were retrospectively reviewed in all patients. Results: One hundred sixty-two of 1,476 (11%) patients who underwent endoscopy had abnormal results on pre-screening coagulation tests. Fourteen patients underwent coagulation factor assays due to abnormal clotting results in consecutive tests or due to clinical evidence of a bleeding tendency. Seven patients were diagnosed with factor XII deficiency, one patient was diagnosed with von Willebrand disease, one patient had von Willebrand disease and factor XII deficiency, and one patient was presumed to have mild hemophilia. The remaining 4 patients had normal results with the factor assays. The results of platelet counts were normal with the exception of 1 patient. No patient had significant bleeding during the endoscopic procedures, despite abnormal pre-endoscopic coagulation tests. Conclusion: Routine coagulation screening tests and platelet counts revealed abnormal results in some patients. Most of the patients with abnormal clotting were shown to have a factor XII deficiency, which had no significant associated bleeding tendencies; the other patients were diagnosed with hemophilia or von Willebrand disease. Therefore, although abnormal pre-endoscopic coagulation is not always related to significant bleeding complications, pre-endoscopic coagulation screening may be useful in some children in predicting the risk of bleeding tendency during endoscopic procedures.

A STUDY OF SIMULATION AND CONTROL OF PAC COSING PROCESS IN WATER PURIFICATION SYSTEM

  • Nahm, Euisuck;Lee, Subum;Woo, Kwangbang;Han, Taehan
    • 제어로봇시스템학회:학술대회논문집
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    • 1995.10a
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    • pp.75-78
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    • 1995
  • In this paper it is concerned to develop control method using jar-test results in order to predict the optimum dosage of coaglant, PAC(PoliAluminum Chloride). Considering the relations with the reactions with the reaction of coagulation and flocculation, the five independent variables ( e, g, turbidity of raw water, water turbidity in flocculators, temperature, pH, and alkalynity) are selected out of parameters and they are put into calculation to develop a neural network model for PAC dosing process in water purification system. This model is utilized to predict optimum dosage of PAC. That is, the optimum dosage of PAC is searched in neural network model for PAC dosing process to minimize the water turbidity in flocculators. This searching is implemented by means of expert heuristics. The efficacy of the proposed contorl schemem and feasibility of acquired neural network model for PAC dosing contorl in water purification system is evaluated by means of computer simulation.

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Neonatal Coagulation Disorder: Diagnostic Approaches for Bleeding Neonates (신생아 혈액 응고질환: 출혈 경향을 보이는 신생아에 대한 진단적 접근)

  • Kim, Chun-Soo
    • Neonatal Medicine
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    • v.18 no.1
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    • pp.6-13
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    • 2011
  • All newborn infants with clinically significant bleeding should be evaluated for a hemostatic deficit. Medical history should include the following data: familial bleeding disorders, maternal illness and medication, age of bleeding onset, and prophylactic administration of vitamin K. The first essential step for evaluating bleeding neonates is determining whether the baby is sick or well. The physician should also evaluate the extent of the bleeding, features of bleeding lesions, and other abnormal findings from the physical examination. Skeletal anomalies may provide diagnostic clues. Depending on the clinical features and results of screening tests, other tests including coagulation factors may be useful for determining the diagnosis. All laboratory results must be considered in the context of age-related reference values. The platelet function analyzer provides a promising alternative to bleeding time. Fibrin degradation products and D-dimers are used for screening and specially testing fibrinolytic activity, respectively. The Apt test may help to rule out factors derived from maternal blood. Radiologic imaging studies are important because asymptomatic intracranial hemorrhages are common in neonates.

Utility Estimation of Pre-filtration on the Membrane Water Treatment Process (막여과 정수처리공정에서 전여과공정의 효용성 평가)

  • Park, Min Koo;Choi, Sang il
    • Journal of Korean Society of Water and Wastewater
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    • v.22 no.4
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    • pp.445-448
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    • 2008
  • The application of the membrane filtration process has been increased for the drinking water treatment system because of excellent quality of treated water compared with the sand filtration process. The selection of suitable pre-treatment processes and optimum flux according to the characteristics of raw water are important factors for the design of membrane processes. In this study, the most efficient pre-treatment processes for drinking water was selected by investigating the effects of pre-treatment processes on the operational stability of the membrane filtration process. Both lab-scale and pilot-scale experiments were conducted. In the lab-scale test, the effect of pre-treatment processes on the stability of the membrane filtration process was investigated indirectly by comparing the performance of membrane flux for raw water, pre-treated water, and membrane permeated water. In the pilot-scale test, the usefulness of prefiltration processes was assessed by comparing the performance of single membrane process and hybrid coagulation-membrane process. The results indicated that the coagulation process contributed to the stabilization of trans-membrane pressure (TMP) by removing contaminants on membranes, though the pre-filtration process had little effect on the TMP.

Minimizing of Residual Aluminum in Water Treatment Process (정수처리공정에서 잔류 알루미늄 최소화 방안)

  • 이미영;조덕희;박종현
    • Proceedings of the Korean Sanitation Conference
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    • 2004.11a
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    • pp.54-65
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    • 2004
  • Use of aluminum salts as coagulants In water treatment may lead to increased concentrations of aluminum in finished water. Aluminum is a suspected causative agent of neurological disorders such as Alzheimer's disease. The objective of this study was to examine variation and minimizing in residual aluminum concentration during water treatment process. The aluminum sources at Bokjeong Water Plant were present naturally aluminum in the raw water and derived due to use of PACS as a coagulant. Much of the raw water total aluminum were in particulate and suspended aluminum. In this study was compared the optimize condition to minimize the concentration of residual aluminum using Jar-test with the various coagulants such as alum, PAC, PACS. The results indicated that PACS was more effective than alum, PAC and insufficient or excessive alum, PAC, PACS addition led to increase residual aluminum. Adjustment raw water pH $6.5\~7.0$ before coagulation using PACS was capable of minimizing total and dissolved aluminum. Thus it is important that the optimal dosage of coagulant and the optimal pH adjustment before coagulation can decided to minimize the concentration of residual aluminum in treated water.

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Optimum Coagulation Conditions for Ceramic Microfiltration Membrane Process (세라믹 정밀여과막 공정을 위한 최적 응집조건)

  • Lim, Jae-Lim;Lee, Kyung-Hyuk;Lee, Young-Joo;Park, Jong-Yul
    • Membrane Journal
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    • v.22 no.2
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    • pp.135-141
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    • 2012
  • This study was carried out to find the optimum coagulation conditions for ceramic microfiltration process of Y water treatment plant. When pH of raw water from Y Dam was adjusted to 7, the efficiency of coagulation was the best and the optimun dosage of coagulant was 3 mg/L(as $Al_2O_3$) for turbidity of raw water less then 10 NTU in Jar test. In mini module test, the decay rate of specific flux was the lowest when PAC (poly Aluminum Chloride) was used among coagulants and pH was adjusted to 7. The decay rate of specific flux for raw water turbidity of 10~30 NTU was greatly decreased with increase of dosage of coagulant (PAC) while the rate was not significantly decreased for turbidity more than 50 NTU. In conclusion, the optimum dosage of PAC (11% as $Al_2O_3$) was 30 and 50 mg/L for raw water turbidity of less than 10 NTU and more than 50 NTU, respectively. The dosage of PAC should be increased linearly 30 to 50 mg/L depending on raw water turbidity of 10 to 50 NTU.

A Study on the improvement of Chemicals Dosing Performance using Neural network in a Purification Plant (신경회로망을 이용한 상수처리설비의 약품주입 성능개선에 관한 연구)

  • 류승기;최도혁;홍규장;문학룡;한태환;유정웅
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.12 no.3
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    • pp.104-113
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    • 1998
  • In genral, the water process facilities include the purification plant, the waste water plant and the process of this purification plant is consisted of the intake, coagulation, settling, filtration, disinfection. The coagulation is very important in filtration processing plant and is very related to process of turbidity. The coagulation to the turbidity is, however, not yet to be clarified and the amount of coagulant can not be easily calculated. Moreover the coagulant dosing amount has to be decided adaptively according to the qualities of the raw water. So, the automation of chemicals dosing process and the supervisory system were needed to improve the performance of facilities. In this paper, a neural network is employed to model the coagulation to the turbidity of the treated water and the historical jar-test data are used to train the neural network. And also, an automation system to support the coagulant dosing process using the neural network was implemented and was shown by the field test. This automation system for the operator support system was constructed the environment to supervise the state an management of facilities for the maintenance.

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Treatability Study on the Remediation Groundwater Contaminated by TPH Cr6+ : Lab-Scale Experiment (TPH와 6가 크롬으로 오염된 지하수 처리를 위한 실내 실험)

  • Lee, Gyu-Beom;Chang, Yoon-Young
    • Journal of Environmental Impact Assessment
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    • v.28 no.3
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    • pp.332-345
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    • 2019
  • The purpose of the study is to evaluate the treatability of contaminated groundwater with TPH and (or) $Cr^{6+}$. Laboratory scale tests were performed for oil/water separation, dissolved air flotation (DAF), coagulation and precipitation, and filtration with sand and activated carbon respectively. Two times of oil/water separation tests for total 40 minutes of separation or separating time shows 90.2 % of TPH removal rate. In case of DAF test for high TPH sample, the TPH removal rates were not varied significantly by the variation of microbubble size. However, tests for low TPH samples show that TPH removal rate increases as microbubbles are smaller. When coagulant was added to sample for DAF test, TPH removal rate was increased 12.3 %. SS removal rate by DAF was 97.9 % at $16-40{\mu}m$ and it was increased as the size of microbubble is reduced. Tests for coagulation and precipitation were performed to evaluate the removal of $Cr^{6+}$ in groundwater. The increase of $FeSO_4$ dosage increased $Cr^{6+}$ removal rate in the coagulation and precipitation process. As the amount of activated carbon in the filter media increased TPH removal rate in the filtration process. SS removal rate by the filtration was 96.7 % similar to the results of DAF process tests. The filtration process treats TPH and SS. Best design parameters are determined as the size of sand is $425-850{\mu}m$ and the ratio of activated carbon and sand is 50:50.

Study on the adsorption of Heavy Metals by Chitin, Chitosan, Cellulose and its Composite Beads (Chintin, Chitosan, Cellulose 및 혼합 Beads의 중금속 이온 흡착특성에 관한 연구)

  • 전수진;유병태
    • Journal of environmental and Sanitary engineering
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    • v.10 no.2
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    • pp.1-12
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    • 1995
  • Under accelerated industrial developments environment pollution comes out to be very stirious. Especially the ions of heavy metal from wastewater, even if they are minimal, accumulated in ecology circle and do finally injury to human health. The general process for removal of heavy metals include coagulation and following sedimentation, ion -exchange and active carbon adsorption and sedimentation that applicate in popular, needs the expense of coagulant the additional treatment of sludge on the general process of coagulation and sedimentation. It is also a serious problem that the second pollution caused by coagulant. However chelating adsorption that uses natural chelating high- molecular compound has not pollution problem Among chelating high- molecules, the diminishing chitin that contained in crustaceans as crawfish and crab in our country with affluent water resources are easy to get. So it is advantageous to use this ubiquitous material for removing heavy metals because we could reuse natural resource. In this research, the author tested the effectiveness of the adsorption and removal of heavy metal ions by chitin and its derivatives. Chitin and cellulose became beads and used as flocculant, in this test. The results are as follows . First, bead showed higher removal ratio than powder in the comparative test on adsorbents such as chitin, chitosan and cellulose. Secondly, in the variety test by the kinds of adsorbent and time. chitosan bead and cellulose bead that showed the highest removal ratio. One hour need to remove the ions of heavy metal. Thirdly, the results of the adsorption degree test by pH revealed high removal ratio adsorption of chitin, cellulose and chitosan bead in alkalin condition but chitosan bead in acidic condition.

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Application of Water Treatment with Membrane in Seomjin River (섬진강 수계에서 막여과 정수처리 공정 적용성 평가)

  • Kim, Jongdoo;Park, Kyungwook;Park, Chulhwi
    • Membrane Journal
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    • v.23 no.1
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    • pp.12-23
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    • 2013
  • On the subject of river bed water in Seomjin river, it had accomplished the verifying experiment of membrane filtration pilot plant for evaluating the applicability of its process throughout the prediction of membrane fouling as a function of the pore size of membrane and the determination of optimum coagulant dosage. On the result of the experiment for the evaluation of the membrane fouling as a function of the pore size, a increasing rate of irreversible resistance of membrane pore size $0.1{\mu}m$ and $0.01{\mu}m$ was measured each $0.44{\times}10^{12}/m^2$ and $0.42{\times}10^{12}/m^2$, respectively. And on the result of Flux-test, it showed that the optimum coagulant dosage was measured lower than the it of the Jar-test. The result to be operated in a condition of a permeate flux $1.0{\sim}1.5m^3/m^2{\cdot}day$ without coagulation and a permeate flux $1.0{\sim}2.0m^3/m^2{\cdot}day$ with coagulation was maintained at stable trans-membrane pressure (TMP) value for 6 months up to. Therefore it showed that the stable operation without the coagulation was possible on permeate flux $1.0{\sim}1.5m^3/m^2{\cdot}day$ in the operation of membrane filtration process.