• Title/Summary/Keyword: Coagulation factors

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Review for Clinical Studies of Oriental Medicine on the Treatment of Ovarian Hyperstimulation Syndrome (난소과자극증후군의 치료에 관한 한의 임상 연구 고찰)

  • Ku, Su-Jeong;Hwang, Deok-Sang;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bock
    • The Journal of Korean Obstetrics and Gynecology
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    • v.33 no.3
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    • pp.60-79
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    • 2020
  • Objectives: This review plans to assess the efficacy and effectiveness of oriental medicine for the treatment of Ovarian Hyperstimulation Syndrome (OHSS) through literature research and overview. Methods: Database searching was conducted to identify relevant randomized controlled trials (RCTs) on oriental medicine for the treatment of Ovarian Hyperstimulation Syndrome. Studies were searched from Journal of Korean Obstetrics and Gynecology, Korean Medical Database, Korean studies Information Service System, China National Knowledge Infrastructure, Cochrane library, PubMed and EmBase up to 21st May, 2020. Results: Seventeen studies were finally selected. Fifteen studies intervened with oral Chinese herb medicine, two studies intervened with acupuncture and moxibustion. Nine studies concluded that intervention with oriental medicine significantly relieved OHSS symptoms. Three studies reporting ovary diameter, four studies reporting abdominal circumference and other four studies reporting pelvic effusion showed significant reduction compared to control groups. Six studies showed significantly shorter duration for hospitalization in intervention groups. Only one study showed significantly higher pregnancy rate. Factors related with vascular permeability and blood cell coagulation were significantly lowered in intervention groups in general. Conclusions: From seventeen studies, oriental medicine relieved OHSS symptoms and showed treatment effectiveness. Further strictly designed studies and long-term observed studies are needed to establish evidences.

Clinical study on Renal Replacement Therapy for Acute Renal Failure following Cardiopulmonary Bypass (체외순환후 급성 심부전에 대한 신대체요법의 임삼적 검토)

  • 서경필
    • Journal of Chest Surgery
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    • v.25 no.3
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    • pp.232-239
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    • 1992
  • Acute renal failure is a well known serious complication following open heart surgery and is associated with a significant increase in morbidity and mortality rate. From 1984 to 1990, 33 patients who had acute renal failure following cardiopulmonary bypass received renal replacement therapy. PD[Peritonial dialysis] was employed in 11 patients and CAVH[continous arteriovenous hemofiltration] was employed in 22 patients. Their age ranged from 3 months to 64 years[mean 25.5$\pm$7.8 years]. The disease entities included congenital cardiac anomaly in 18, valvular heart disease in 15 and aorta disease in 2 cases. Low cardiac output was thought as a primary cause of ARF except two redo valve cases who showed severe Aemolysis k depressed renal function preoperatively. Mean serum BUN and creatinine level at the onset renal replacement therapy were 65$\pm$8 mg/dl and 3.5$\pm$0.4 mg/dl respectively, declining only after reaching peak level 7&10 days following the onset of therapy. Overall hospital mortality was 72.7%[24/33]; 81%[9/11] in PD group and 68.2% [15/22] in CAVH group respectively. The primary cause of death was low cardiac output & hemodynamic depression in all the cases. The fatal complications included multiorgan failure in 7, disseminated intravascular coagulation and sepsis in 6, neurologic damage in 4 and mediastinitis in 3 cases. No measurable differences were observed between CAVH and PD group upon consequence of acute renal failure and disease per se. The age at operation, BUN/Cr level at the onset of bypass and highest BUN/Cr level and the consequence of low output status were regarded as important risk factors, determining outcome of ARF and success of renal replacement therapy. Thus, we concluded that althoght the prognosis is largely determined by severity of low cardiac output status and other organ complication, early institution of renal replacement therapy with other intensive supportive measures could improve salvage rate in established ARF patients following CPB.

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A Study on the Intervertebral Disc Temperature Distribution During Electrothermal Therapy (추간판의 전기열치료시 온도분포에 관한 연구)

  • 진의덕;탁계래;구자중;김한성;이성재;이정한
    • Journal of Biomedical Engineering Research
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    • v.24 no.1
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    • pp.23-29
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    • 2003
  • The prevalence of discogenic pain among patients with chronic low back pain is estimated to be about 40%. Lumbar discectomy is being performed as a treatment according to the studies done so far. Recently IDET- Intradiscal electrothermal therapy which is minimally invasive technique is being introduced. This study will investigate important factors of this procedure such as the temperature of heat source, loading times, and the temperature distribution within the intervertebral disc. This study utilized finite element analysis and experiment. It was able to analyze the temperature range of inner intervertebral disc by two mechanisms which are known to alleviate pain clinically. As a result, verification of temperature distribution to 15.6mm($\geq$45$^{\circ}C$) (Mechanism 1-coagulation inner annulus by heat) and 9mm($\geq$6$0^{\circ}C$) (Mechanism 2- contraction inner nucleus by heat) from the heat source was done.

Study of Scientific Comparison for the Characteristics of Black Ware Excavated from White Porcelain Kiln of Yongyeon-ri, Damyang and those of Other Regions

  • Choi, Jae Won;Han, Min Su
    • Journal of Conservation Science
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    • v.35 no.4
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    • pp.331-343
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    • 2019
  • The purpose of this study was to investigate the material characteristics of black wares excavated from Yongyeon-ri, Damyang and to clarify the correlation of the factors that develop black coulor compared with black wares excavated from other regions. As a results of absorption rate, colour coordinate, compositional mineral, section analysis and contents showed high correlation between the kilns and the waste dumplings, indicating that they were made using the same materials. Second, comparing the microtextures and contents of the glaze layer with the excavated sherds from other kilns, a characteristic coagulation phenomena of iron oxides were not observed in Yongyeon-ri and Gilmyeong-ri, and it was considered that the material, mixing ratio, and firing environment were different from those of Bonggok-dong. In addition, statistical analysis using the major components revealed that the bodies of Yongyeon-ri were highly correlated with those of Bonggok-dong, which is nearest to the region, and similar to Gilmyeong-ri in the glaze layer. The characteristics of colorant were different depending on Fe2O3 content and K2O content also contributed to the classification of the composition of each excavated kiln. Conclusionally, it can be seen from the scientific analysis that the colour of black wares excluded from different regions is materially different from that of iron oxide, the coloring condition, and the firing environment.

Separation Technologies for the Removal of Nitrate-Nitrogen from Aqueous Solution (수용액으로부터 질산성질소 제거를 위한 기술)

  • Seo, Yang Gon;Jung, Se Yeong
    • Clean Technology
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    • v.23 no.1
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    • pp.1-14
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    • 2017
  • At high nitrate concentrations, water must be treated to meet regulated concentrations because it results in threat to human health and eutrophication of natural water. However, it is almost impossible to remove nitrate by conventional water treatment methods such as coagulation, filtration and precipitation, due to its high water solubility. Therefore, other technologies including adsorption, ion exchange, reverse osmosis, denitrification, and electrodialysis are required to effectively remove nitrate. Each of these technologies has their own strengths and drawbacks and their feasibility is weighted against factors such as cost, water quality improvement, residuals handling, and pre-treatment requirements. An adsorption technique is the most popular and common process because of its cost effectiveness, ease of operation, and simplicity of design. Surface modifications of adsorbents have been enhanced their adsorption of nitrate. The nitrate-selective membrane process of electrodialysis reversal and reverse osmosis have proven over time and at many locations to be highly effective in removing nitrate contaminating problems in aqueous solutions. Both electrodiaysis and reverse osmosis methods generate highly concentrated wastes and need careful consideration with respect to disposal.

An Investigation on Surgical Parameters for the Treatment of Intervertebral Disc during Electrothermal Therapy (디스크의 전기열치료시 수술변수에 관한 연구)

  • Jin E.D.;Choi J.S.;Tack G.R.;Lee B.S.;Lee B.Y.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.513-514
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    • 2006
  • Recently intradiscal electrothermal therapy is introduced, which is a new and minimally invasive technique fer the treatment of discogenic low back pain. This procedure involves the percutaneous threading of a flexible catheter into the disc under fluoroscopic guidance. The catheter, composed of thermal resistive coil, heats the posterior annulus of the disc, causing contraction of collagen fibers and destruction of afferent nociceptors. This study tries to investigate the effects of the important factors of this procedure such as heat source temperature and heat applying time on the temperature distribution within the intervertebral disc. This study utilized both computer simulation and the experiment for the verification of finite element analysis. FE analysis was carried out with ANSYS v7.0 (ANSYS Inc, USA) using 10,980 number of brick element and 12,551 number of node. The functional spinal units of 5 month old swine were used for the experiment and the temperature was monitored using 10 channel temperature measurement device MV200. Through this study, it was able to analyze the temperature range of inner intervertebral disc by two mechanisms which are known to alleviate pain clinically. The results showed that when the heat source temperature was kept up 80 degree for 1,020 seconds, the temperature of inner annulus reached at 45 degree up to the distance of 15.6mm from heat source, which explains coagulation of inner annulus by heat. When the same heat source was used, the temperature of inner nucleus reached at 60 degree up to the distance of 9mm from heat source, which explains contraction of inner nucleus by heat.

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Group A ${\beta}$-hemolytic Streptococcal Meningoencephalitis with Unilateral Hemiparesis (일측성 편마비를 동반한 A군 ${\beta}$-용혈성 사슬알균 수막뇌염 1례)

  • Kim, Ki-Won;Soon, Eu-Gene;Cha, Byung Ho;Lee, Hae Yong;Uh, Young;Kim, Sunjoo;Chun, Jin-Kyong
    • Pediatric Infection and Vaccine
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    • v.16 no.2
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    • pp.210-214
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    • 2009
  • Group A streptococcus (GAS) rarely causes meningoencephalitis in children without risk factors. A previously healthy 8 year-old child presented with lethargy, high fever, and vomiting. The clinical course was unusual including intractable seizures, disseminated intravascular coagulation (DIC), and left hemiparesis in spite of the appropriate and timely administration of antibiotics and corticosteroids. The microbiologic studies revealed that the pathogen was susceptible to penicillin and GAS M18 strains. This case showed the importance of the GAS vaccine in addition to appropriate antibiotics.

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Liquid Velocity and Local Fouling in Coagulation-submerged Microfiltration Module for Drinking Water Treatment (정수처리를 위한 응집-침지식 정밀여과 모듈의 유체유속 및 국부오염)

  • Choi, Youngkeun;Kim, Hyun-Chul;Noh, Soohong
    • Membrane Journal
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    • v.25 no.3
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    • pp.268-275
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    • 2015
  • Effects of aeration intensity on local fouling were investigated in submerged membrane modules. Higher liquid velocities were observed at the section with the lower fiber packing density. The liquid velocity is increased with increasing the gas-liquid injection factor. The high shear stress coincided with the high liquid velocity. The shear stress increases with the increasing of gas-liquid injection factor and the liquid velocity improves with the increasing of gas-liquid injection factor. Irreversible fouling resistance ($R_{ir}$) of the fiber position is significant in a local region of high suction pressure near the suction point of the fiber (position 1). The ratio of $R_{ir}/R_m$ and $R_{ir}/R_r$ of position 1 was highest compared to the position 2 and 3. Irreversible fouling resistances results confirmed the preferential deposition of foulants near the suction part of the fiber where the local suction pressure is the highest and correspondingly, more particles are accumulated to the membrane surface. The effects of local fouling along the fiber length are significant factors to optimize the design of submerged modules.

Studies on Liquefaction of Semen (정액(精液)의 액화(液化)에 관한 연구(硏究))

  • Kim, Suk-Hee;Lee, Hee-Yong
    • Clinical and Experimental Reproductive Medicine
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    • v.3 no.2
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    • pp.35-42
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    • 1976
  • The human semen ejaculated in a form of liquid state, coagulates immediately after ejaculation, and then liquefies again. However, the mechanisms of neither coagulation and liquefaction of semen have not been explained clearly so far, and very limited numbers of report are available, although the spermatology and andrology made rapid progress. This clinical study has been undertaken to investigate the liquefaction phenomena and practicability of the results might be applied to fertility and infertility problems. As a preliminary study, in this report the liquefaction time of various semen groups is measured and analysed. The following results are obtained: 1. An average liquefaction time of semen of a total of 60 subjects: 25 minutes. 2. An average liquefaction time of semen according to sperm count: 1) Normospermia group (20 cases): 34 minutes. 2) Oligospermia group (20 cases): 21 minutes. 3) Azoospermia group (20 cases): 20 minutes. 3. An average liquefaction time of semen according to abstinence period: 1) Less than 3 days group (30 cases): 22 minutes. 2) More then 5 days group (30 cases): 28 minutes. In conclusion: 1. The liquefaction time of semen of the normospermia group is longer than oligospermia group or azoosermia group. 2. The liquefaction time of semen may not be greatly influenced by the various factors such as abstinence period, semen volume, semen pH, age of the subjects and so on. 3. In routine semen analyses, it is recommended to begin the analysis at least 25 minutes after the ejaculation. 4. Further studies are required in conjunction with practical application of liquefaction mechanism in infertility and fertility control.

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The Changes of Serologic Markers in Pneumoconiosis of Coal Workers (진폐증 환자에서의 혈청학적 표지자의 변화)

  • Yoo, Kwang-Ha;Yun, Ho-Sang;Lee, Sang-Yeup;Jin, Choon-Jo;Ahn, Cheol-Min;Kim, Hyung-Joong
    • Tuberculosis and Respiratory Diseases
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    • v.50 no.5
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    • pp.615-623
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    • 2001
  • Background : Pneumoconiosis is a parenchymal lung disease that results from the accumulation of coal dust in the lungs and the consequent tissue reaction. To evaluate the role of various personal factors in pneumoconiosis and the significance of some serologic markers for assessing the disease activity related to pneumoconiosis, the Rheumatoid Factor(RF), ${\alpha}_1$-AT, C-Reactive Protein(CRP), ceruloplasmin and fibrinogen levels were measured. Method : All the patients were males, 45-76 years old, and the mean duration of coal dust exposure was 23.2 years. 51 patients were classified as having Simple Pneumoconiosis (SP), 59 had Progressive Massive Fibrosis (PMF). Fifty eight men with ages ranging from 26-70 years were used as normal controls. The serum RF and CRP were titrated using an Autochemistry analyzer (HITACHI 7150 : Japan) and the ${\alpha}_1$-AT and ceruloplasmin levels were measured using a Nephelometer (Behring Nephelometer : Germany) and the fibrinogen levels were estimated by using an Autoanalyzer for hematologic coagulation. Result : There was a higher RF level in the SP, and PMF groups than in the control groups but there was no statistical difference. The CRP, ${\alpha}_1$-AT, and ceruloplasmin levels were also higher in the SP, and PMF groups. However, the fibrinogen concentration was within the normal ranges in both the SP and PMF groups. Conclusion : The CWP (Ed note : Define CWP) patients had significantly higher CRP, ${\alpha}_1$-AT, and ceruloplasmin levels compared to the control group. It is believed that these serologic changes could be used as a marker of the disease activity.

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