• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 2005년도 추계 학술대회논문집
• /
• pp.55-59
• /
• 2005

CFD analysis has been conducted to find the two stage impeller configuration which is the most suitable for a stirred tank with an internal helical cooling coil and a cooling jacket, which is frequently used in chemical industries for highly exothermic reactions ranged from low to medium viscosity. Two typical types of impellers are considered; pitched paddle impellers and Rushton turbine impellers. Interestingly, pitched paddle impellers show a good mixing performance for multi-species, whereas Rushton turbine impellers achieve a good mixing performance for multi-phases. Besides the type of an impeller, the location of an impeller is another important factor to be considered in order to accomplish an effective mixing. The best set of types and locations of two impellers is recommended based on the coefficient of variation(CoV) value and the heat removal capability obtained from CFD results. The former is a measure to quantify the degree of mixing.

• 전자공학회논문지B
• /
• 제29B권10호
• /
• pp.78-89
• /
• 1992

In this paper, a multiresolution edge detction algorithm for speckle images is proposed. Due to the signal dependency of speckle images, the number of edge points detected depends on the local average intensity. Thus the edge detection method independent of the average intensity is required to detect properly real significant changes in an original signal. In the proposed method, candidate area is first selected based on the statistical propeties of speckle images,i.e., based on the busyness measure such as the CoV(coefficient of variation) and the difference between the real and theoretical CDF(cumulative density function). Then the real edges are extracted in a multiresolution environment. Computer simulation with test images shows that the proposed method reduces significantly false edges in relatively homogeneous areas while detects fine details properly.

• 한국전기전자재료학회논문지
• /
• 제13권8호
• /
• pp.667-674
• /
• 2000

The stability of ZnO-Pr$_{6}$/O$_{11}$-CoO-Er$_{2}$/O$_3$based varistors was investigated with Er$_{2}$/O$_3$additive content of the range 0.0 to 2.0 mol%. All varistors sintered at 130$0^{\circ}C$ exhibited the thermal runaway within short times even under weak d.c. stress. As a result these varistors were completely degraded. On the contrary the stability of varistors sintered at 135$0^{\circ}C$ was far better than that of 130$0^{\circ}C$. In particular the varistors added with 0.5mol% Er$_{2}$/O$_3$ which the nonlinear exponent is 34.83 and the leakage current is 7.38 $mutextrm{A}$ showed a excellent stability which the variation rate of the varistors voltage the nonlinear coefficient and the leakage current is below 1%, 2%, and 3.5% respectively even under more severe d.c. stress such as (0.80 V$_{1mA}$9$0^{\circ}C$/12h)+(0.85 V$_{1mA}$115$^{\circ}C$/12h)+(0.90 V$_{1mA}$12$0^{\circ}C$12h) Consequently it is estimated that the ZnO-0.5 mol% Pr$_{6}$/O sub 11/-1.0 mol% CoO-0.5 mol% Er$_{2}$/O sub 3/ based varistors will be used to develop the advanced Pr$_{6}$/O$_{11}$-1.0 mol% CoO-0.5 mol% Er$_{2}$/O$_{3}$ based varistors will be used to develop the advanced Pr$_{6}$/O$_{11}$-based ZnO varistors having the high performance and stability in future. future.ure. future.

• 한국해양학회지
• /
• 제26권1호
• /
• pp.59-66
• /
• 1991

동해 심해분지 시추퇴적물 (수심, 1850 m 에서 수평(H), 수직(V) 방향에 대한 음 속(V/SUB p/)과 감쇠계수 (q/SUB p/)가 실내분석방법으로 측정되었다. 채취된 시추퇴 적물이 길이는 약 250 m 이었으며, 측정 음원은 중심주파수 500 m 의 초음파 변환기 (ultrasonic p-wave transducer)가 사용되었다. 1,480~1,500 m/sec 정도의 변화를 보 이는 V/SUB p/의 비동방성 (A/SUB p/)은 $\pm$1.0% 이내로써, 수평 또는 수직 그 어느 쪽 이 빠르다고 판단하기는 어렵다. 이는 시료의 대부분이 균질 (homogeneous) 한 니질퇴 적상이며, 심한 생물교란 (bioturbation)과 함께 높은 공극율(85% 이상)에 따른 다량 의 해수 함유에 기인하는 것으로 판단된다. Q/SUB p/의 분포범위는 5~10 정도이며 전 반적으로 퇴적물 하부로 내려갈수록 감소하는 경향은 탄산염 (CaC0$_3$)과 유기물 함량 의 증가와 함께 silt가 증가하고 clay가 감소하는 퇴적물 입도 (texture)의 변화로 해 석된다. 그러나 화산재(volcanic ash)가 나타나는 최하부층에서는 14.9 의 높은 Q/SUB PH/값도 보이고 있다. V/SUB PH/와 Q/SUB PH/의 역상관관계는 퇴적물 물성변화 뿐만 아니라 높은 함수율로 인한 해수특성(높은 Q/SUB p/, 낮은 V/SUB p/)의 영향도 크게 작용하고 있음을 시사한다.

• Advances in aircraft and spacecraft science
• /
• 제4권5호
• /
• pp.585-611
• /
• 2017

This article covenants with the post buckling witticism of carbon nanotube reinforced composite (CNTRC) beam supported with an elastic foundation in thermal atmospheres with arbitrary assumed random system properties. The arbitrary assumed random system properties are be modeled as uncorrelated Gaussian random input variables. Unvaryingly distributed (UD) and functionally graded (FG) distributions of the carbon nanotube are deliberated. The material belongings of CNTRC beam are presumed to be graded in the beam depth way and appraised through a micromechanical exemplary. The basic equations of a CNTRC beam are imitative constructed on a higher order shear deformation beam (HSDT) theory with von-Karman type nonlinearity. The beam is supported by two parameters Pasternak elastic foundation with Winkler cubic nonlinearity. The thermal dominance is involved in the material properties of CNTRC beam is foreseen to be temperature dependent (TD). The first and second order perturbation method (SOPT) and Monte Carlo sampling (MCS) by way of CO nonlinear finite element method (FEM) through direct iterative way are offered to observe the mean, coefficient of variation (COV) and probability distribution function (PDF) of critical post buckling load. Archetypal outcomes are presented for the volume fraction of CNTRC, slenderness ratios, boundary conditions, underpinning parameters, amplitude ratios, temperature reliant and sovereign random material properties with arbitrary system properties. The present defined tactic is corroborated with the results available in the literature and by employing MCS.

• Archives of Pharmacal Research
• /
• 제27권9호
• /
• pp.901-905
• /
• 2004

A rapid, sensitive and selective hydrophilic interaction liquid chromatography-tandem mass spectrometric(HILIC-MS/MS) method for the determination of tiapride in human plasma was developed. Tiapride and internal standard, metoclopramide were extracted from human plasma with dichloromethane at basic pH and analyzed on an Atlantis HILIC silica column with the mobile phase of acetonitrile-ammonium formate (190 mM, pH 3.0) (94：6, v/v). The ana-Iytes were detected using an electrospray ionization tandem mass spectrometry in the multi-ple-reaction-monitoring mode. The standard curve was linear (r＝0.999) over the concentration range of 1.00-200 ng/mL. The coefficient of variation and relative error for intra- and inter-assay at three QC levels were 6.4∼8.8％ and -2.0∼3.6％, respectively. The recoveries of tiapride ranged from 96.3 to 97.4％, with that of metoclopramide (internal standard) being 94.2％. The lower limit of quantification for tiapride was 1.00 ng/mL using 1 00 $\mu$L of plasma sample.

• 한국균학회소식:학술대회논문집
• /
• 한국균학회 2014년도 춘계학술대회 및 임시총회
• /
• pp.19-19
• /
• 2014

This study included the analysis of mushroom data collected from Mt. Chiak in Gangwon-do using various methods. Former studies of Korean mushrooms are limited by regional characters and there is less species diversity among the regions. This study tried to find a way for the forecast of mushroom distribution and appearance by indexes of species diversity. The indexes used in this study include the number of fungi (N), the number of species (S), similarity index (C), richness index (R1, R2), variety index (V1, V2), evenness index (E1, E2, E3, E4, E5), and dominance index (D1) to analyze variety of species diversity. Analyses of data of fungi using a multistage cluster sampling indicate that the average value of C for years was higher than the average value of C for areas. The mushrooms consisted of 208 species in 686 individuals in limited fungal collection from 2002 to 2003. One hundred thirty nine species in 393 individuals were collected in 2002, and 122 species 293 individuals were collected in 2003. The individuals collected in 2003 were smaller than 2002's individuals. Similarity, richness, and variety indexes' values of 2003 were reduced than 2002's values but dominance index of 2003 was increased than 2002's value. Generally the species diversity of the environment to evaluate the index of similarity, richness, and variety was a higher index; dominance index was lower than that of the surrounding environment, suggesting a good diversity. As a result, the occurrence of mushrooms in the surrounding environment and the various factors seem fell in 2002 compared to 2003. The majority genus of the limited fungal collection was Mycena genus in 63 individuals; the majority species was Laccaria laccata in 34 individuals. Ninety three species in 106 individuals were collected by the extended collection and the majority genus of the extended collection was Amanita genus in 17 individuals; the majority species was Amanita citrina (Schaeff.) Pers. which was found in 5 individuals. This demonstrates that periodical similarity's value was 0.159 is higher than special similarity's 0.119. This indicates that the probability of the appearance of same mushrooms in the same area in following year is higher than the probability of the appearance of same mushrooms in the surrounding area in same year. The value of coefficient of variation (CV), in which the amount of change is much or less by N is higher than the CV value by S. CV value of dominance index(D) was the highest r point among other indexes, and evenness index (E) was the lowest point among other indexes. The correlation matrix with 66 combinations between the indexes, the combinations with correlations was 46 combinations. These results revealed that indexes of R1, V2, and E1 were proper to represent species diversity of fungi based on the correlation matrix and the theory of statistical independence which means there is no or less mutual association. This research would contribute to the study about variable living creature by measuring method and in the future this would be used to figure out regulation about fungi with their correlation, values in ecosystem, develop improving new models about agricultural fungi species and numbers by investigating agricultural variable species.

• 한국환경농학회지
• /
• 제40권2호
• /
• pp.134-141
• /
• 2021

본 연구는 축산물 중 퀴녹사린계 살균제 chinomethionat의 잔류분석법을 확립하였다. 소고기, 돼지고기, 닭고기, 우유, 계란을 대표 시료로 선정하고 GC-ECD를 이용한 chinomethionat 단성분 정량 시험법을 개발하였다. 축산물 중 chinomethionat 잔류물을 acetone/dichloromethane (9/1, v/v)로 추출하고 추출첨가제 MgSO₄ 및 NaCl을 첨가한 후, dichloromethane로 분배하고 Florisil 흡착제로 정제하였다. 축산물 중 chinomethionat 정량한계는 0.02 mg/kg으로 결정되었으며, MLOQ 수준의 회수율은 84.8-100.9%, MLOQ 10배 수준에서는 85.7-103.0%의 우수한 회수율을 보였으며, 분석오차는 최대 5.2%로 재현성 역시 양호하였다. 본 연구에서 확립한 chinomethionat의 잔류분석법은 국내·외 축산물의 잔류농약 검사 및 분석에 적용 가능할 것으로 기대된다.

• Biomolecules & Therapeutics
• /
• 제6권2호
• /
• pp.219-224
• /
• 1998

The bioequivalence of two clarithromvcin products was evaluated with 16 normal male volunteers (age 23-28 yr, body weight 57.5-75.517g) following single oral dose. Test product was ReYon Clarithromycin tablets (ReYon Pharm. Corp., Korea) and reference product was Klarici $d_{R}$ tablets (Abbott Korea). Both products contain 250 mg of clarithromucin. One tablet of the test or the reference product was administered to the volunteers, respectively, by randomized two period cross-over study (2$\times$2 Latin square method). The determination of clarithromycin was accomplished using a modified agar well diffusion bioassay. As a result of the assay validation, the quantification of clarithromycin in human serum by this technique was possible down to 0.03$\mu$g/ml using 100$\mu$l of serum. The coefficient of variation (C.V.) was less than 10%. Average drug concentrations at each sampling time and pharmacokinetic parameters calculated were not significantly different between two products P>0.05); the area under the curve to last sampling time (24 hr) (AU $Co_{24hr}$ (8.10$\pm$ 1.26 vs 8.22$\pm$ 1.627g . hr/ml), AUC from time zero to infinite (AU $Co_{\infty}$) (8.61 $\pm$ 1.28 vs 8.84$\pm$ 1.71 $\mu$g . hr/ml), maximum plasma concentration ( $C_{msx}$) (0.87$\pm$0.22 vs 0.88$\pm$0.19 $\mu$g/ml) and time to maximum plasma concentration ( $T_{max}$) (2.69 $\pm$0.48 vs 2.56$\pm$ 0.51 hr). The differences of mean AU $Co_{24h}$, $C_{msx}$ and $T_{msx}$ between the two products (1.44, 1.39, and 4.65%, respectively) were less than 20%. The power (1-$\beta$) and treatment difference ($\Delta$) for AU $Co_{24hr}$, and $C_{max}$ were more than 0.8 and less than 0.2, respectivly. Although the power for $T_{max}$ was under 0.8, $T_{max}$. of the two products was not significantly different each other (p>0.05). These results suggest that the bioavailability of ReYon Clarithromycin tablets is not significantly different from that of Klarici $d_{R}$ tablets. Therefore, two products are bioequivalent based on the current results. results.sults.sults.s.s.s.s.s.s.s.

• 전자공학회논문지
• /
• 제53권6호
• /
• pp.155-166
• /
• 2016

전자유도 가열시설에서 정밀하고 일정한 주파수 성분에 의해 가열물체에 발열을 유도하려면 LC공진회로 설계단계에서 출력 주파수에 대한 커패시터의 정전용량(C)과 워크코일의 유도계수(L) 설정이 중요하다. 하지만 고유의 발열계수를 가진 물체의 가열위치와 범위에 직접유도를 하는 워크코일은 고정적으로 설계되는 반면 커패시터는 가변되도록 설계되어야만 전체장비의 활용도가 높아진다. 본 논문에서는 $1000V_{MAX}$ 최대전압과 $200I_{MAX}$ 전류에서 최대 700kHz의 고주파 LC공진 출력이 되도록 커패시터 내부구성 원자재 선정 및 공정설계 단계까지 단일전극 용량별 샘플을 추출하였다. 그리고 정전용량 규격변화에 따라 주파수 변화특성과 출력 파라메타 결과를 바탕으로 HF-LC공진용 전도냉각 커패시터의 최적설계를 위한 관계를 증명하는 기초 실험결과를 제시하였다.