• 해양환경안전학회지
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• 제12권2호
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• pp.157-163
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• 2006

현재 대기중 $CO_2$ 농도를 감소시키기 위하여 $CO_2$를 해양에 격리 처리하고자 하는 방안이 모색되고 있으나 이러한 방안은 해양생물 및 생태계에 미치는 영향 정도에 따라 그 실현가능성이 결정될 것이다. 본 연구에서는 $CO_2$ 해양격리 처리와 관련하여 수행되어온 연구들을 정리하고, $CO_2$ 농도가 높아진 해양환경에서의 해양생물 특히 어류를 대상으로 수행된 최근의 연구결과를 정리하였다. $CO_2$ 농도의 증가는 어류에 있어 산염기조절, 호흡순환기적 조절 등과 같은 생리적 기능에 영향을 끼치고 결국 어류의 폐사를 초래할 것이다. $CO_2$가 해양생물에게 어떠한 영향을 미치는가에 대한 연구는 주로 천해어종을 대상으로 하여 진행되어 왔으나 향후의 연구는 천해어종에 대한 연구결과를 바탕으로 $CO_2$가 실제로 격리 처리되는 심해에서 $CO_2$에 대한 생물들의 응답에 관하여 조사할 필요가 있다.

• Asian-Australasian Journal of Animal Sciences
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• 제33권3호
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• pp.398-407
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• 2020

Objective: The Yip1 domain family (YIPF) proteins were proposed to function in endoplasmic reticulum (ER) to Golgi transport and maintenance of the morphology of the Golgi, which were homologues of yeast Yip1p and Yif1p. YIPF3, the member 3 of YIPF family was a homolog of Yif1p. The aim of present study was to investigate the expression and regulation mechanism of porcine YIPF3. Methods: Quantitative realtime polymerase chain reaction (qPCR) was used to analyze porcine YIPF3 mRNA expression pattern in different tissues and pig kidney epithelial (PK15) cells stimulated by polyinosine-polycytidylic acid (poly [I:C]). Site-directed mutations combined with dual luciferase reporter assays and electrophoretic mobility shift assay (EMSA) were employed to reveal transcription regulation mechanism of porcine YIPF3. Results: Results showed that the mRNA of porcine YIPF3 (pYIPF3) was widely expressed with the highest levels in lymph and lung followed by spleen and liver, while weak in heart and skeletal muscle. Subcellular localization results indicated that it expressed in Golgi apparatus and plasma membranes. Upon stimulation with poly (I:C), the level of this gene was dramatically up-regulated in a time- and concentration-dependent manner. pYIPF3 core promoter region harbored three cis-acting elements which were bound by ETS proto-oncogene 2 (ETS2), zinc finger and BTB domain containing 4 (ZBTB4), and zinc finger and BTB domain containing 14 (ZBTB14), respectively. In which, ETS2 and ZBTB4 both promoted pYIPF3 transcription activity while ZBTB14 inhibited it, and these three transcription factors all played important regulation roles in tumorigenesis and apoptosis. Conclusion: The pYIPF3 mRNA expression was regulated by ETS2, ZBTB4, and ZBTB14, and its higher expression in immune organs might contribute to enhancing ER to Golgi transport of proteins, thus adapting to the immune response.

• Molecules and Cells
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• 제40권3호
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• pp.169-177
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• 2017

Tissue-specific transcription is critical for normal development, and abnormalities causing undesirable gene expression may lead to diseases such as cancer. Such highly organized transcription is controlled by enhancers with specific DNA sequences recognized by transcription factors. Enhancers are associated with chromatin modifications that are distinct epigenetic features in a tissue-specific manner. Recently, super-enhancers comprising enhancer clusters co-occupied by lineage-specific factors have been identified in diverse cell types such as adipocytes, hair follicle stem cells, and mammary epithelial cells. In addition, noncoding RNAs, named eRNAs, are synthesized at super-enhancer regions before their target genes are transcribed. Many functional studies revealed that super-enhancers and eRNAs are essential for the regulation of tissue-specific gene expression. In this review, we summarize recent findings concerning enhancer function in tissue-specific gene regulation and cancer development.

• 한국공작기계학회논문집
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• 제13권5호
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• pp.110-117
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• 2004

In automatic welding process using a robot, seam tracking is one of the important parts. Sensor for seam tracking is divided broadly into two categories as non contact sensor and contact sensor. The arc sensor is one of the non contact sensors, and it can be applied in weaving arc and rotating arc welding process. In such the arc sensors, rotating arc sensor can be applied to high speed welding over tens of Hz. The decrease of self regulation by high rotating speed causes to improve accuracy and response of sensor. In this study, fuzzy controller was used to track the seam for the $CO_2$ arc welding which had unstable arc. It could be shown that the rotating arc sensor was better than the weaving arc sensor.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 하계학술대회 논문집 D
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• pp.2568-2571
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• 2002

A LCD backlight inverter control IC based on the piezoelectric transformer (PZT) for Cold Cathode Fluorescent Lamp (CCFL) lighting is proposed. It is indeed a variable frequency, variable duty (VFVD) controller having dual feedback control loops for achieving both the regulation of lamp current and the maximum efficiency. The PWM controller regulates the lamp current, while the PLL controller tunes the operating frequency to the frequency that the efficiency of the combined LC-PZT resonator becomes maximum. The mixed PLL/PWM control technique lets the backlight inverter operate at the maximum efficiency in spite of the variation of component and environment. The controller features include a protection for an open or broken lamps, and an open lamp regulation.

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2005년도 춘계학술대회 및 국제심포지움 초록집
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• pp.190-190
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• 2005

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2005년도 춘계학술대회 및 국제심포지움 초록집
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• pp.109-109
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• 2005

• 열처리공학회지
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• 제21권2호
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• pp.101-110
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• 2008

• 한국윤활학회:학술대회논문집
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• 한국윤활학회 2002년도 제35회 춘계학술대회
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• pp.111-119
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• 2002

• 자원ㆍ환경경제연구
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• 제18권3호
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• pp.523-544
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• 2009

본 연구는 목적은 내생적 환경정책모형(endogenous environmental policy)에 기초하여 외국인직접투자(foreign direct investment), 경제성장, 환경규제의 상호관계를 실증적으로 분석하는 것이다. 외국인자본비율의 1% 증가는 0.044%(고정효과), 0.047%(확률효과)의 경제성장효과를 유발하였으며, 노동자 1인당 생산량의 1% 증가는 2.038%(고정효과), 1.890%(확률효과)의 환경규제강화를 유도하는 것으로 계측되었다. 그러나 생산 과정에 있어 강력한 환경규제가 기술혁신의 유인으로 작용한다는 포터의 가설(Porter's theory)을 지지할 만한 실증결과는 보여주지 못하였다. 또한 2개의 대기오염물질 (NOx, $CO_2$)을 기준으로 규모효과(0.0119, 0.0172)가 기술효과(-0.0048, -0.0007)보다 크게 추정되었다. 이는 국제사회의 꾸준한 노력에도 불구하고 더욱 적극적인 환경보호를 위해 각국의 공공지출액을 증액시킬 필요성이 있음을 의미한다.