• Journal of the Korean Society of Marine Environment & Safety
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• v.12 no.2 s.25
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• pp.157-163
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• 2006

The scenario of $CO_2$ disposal in the deep-sea are thought to be possible method to reduce atmospheric $CO_2$ concentrations. However, it is necessary to clarify the effects of elevated $CO_2$ concentrations on both marine organisms and marine ecosystems. In this paper the literatures on the biological impact of elevated $CO_2$ concentrations in seawater and recent studies on the effects of elevated $CO_2$ concentrations on marine animals are reviewed. Elevated $CO_2$ concentrations may affect the physiological functions of marine animals such as acid-base regulation, blood oxygen transport and respiratory system, and ultimately lead to the death of marine animals. Although the fish used in the early studies on $CO_2$ effects are temperate, shallow-water species, deep-sea species should be experimented for the future study on $CO_2$ sequestration in the deep ocean.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.3
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• pp.398-407
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• 2020

Objective: The Yip1 domain family (YIPF) proteins were proposed to function in endoplasmic reticulum (ER) to Golgi transport and maintenance of the morphology of the Golgi, which were homologues of yeast Yip1p and Yif1p. YIPF3, the member 3 of YIPF family was a homolog of Yif1p. The aim of present study was to investigate the expression and regulation mechanism of porcine YIPF3. Methods: Quantitative realtime polymerase chain reaction (qPCR) was used to analyze porcine YIPF3 mRNA expression pattern in different tissues and pig kidney epithelial (PK15) cells stimulated by polyinosine-polycytidylic acid (poly [I:C]). Site-directed mutations combined with dual luciferase reporter assays and electrophoretic mobility shift assay (EMSA) were employed to reveal transcription regulation mechanism of porcine YIPF3. Results: Results showed that the mRNA of porcine YIPF3 (pYIPF3) was widely expressed with the highest levels in lymph and lung followed by spleen and liver, while weak in heart and skeletal muscle. Subcellular localization results indicated that it expressed in Golgi apparatus and plasma membranes. Upon stimulation with poly (I:C), the level of this gene was dramatically up-regulated in a time- and concentration-dependent manner. pYIPF3 core promoter region harbored three cis-acting elements which were bound by ETS proto-oncogene 2 (ETS2), zinc finger and BTB domain containing 4 (ZBTB4), and zinc finger and BTB domain containing 14 (ZBTB14), respectively. In which, ETS2 and ZBTB4 both promoted pYIPF3 transcription activity while ZBTB14 inhibited it, and these three transcription factors all played important regulation roles in tumorigenesis and apoptosis. Conclusion: The pYIPF3 mRNA expression was regulated by ETS2, ZBTB4, and ZBTB14, and its higher expression in immune organs might contribute to enhancing ER to Golgi transport of proteins, thus adapting to the immune response.

• Molecules and Cells
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• v.40 no.3
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• pp.169-177
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• 2017

Tissue-specific transcription is critical for normal development, and abnormalities causing undesirable gene expression may lead to diseases such as cancer. Such highly organized transcription is controlled by enhancers with specific DNA sequences recognized by transcription factors. Enhancers are associated with chromatin modifications that are distinct epigenetic features in a tissue-specific manner. Recently, super-enhancers comprising enhancer clusters co-occupied by lineage-specific factors have been identified in diverse cell types such as adipocytes, hair follicle stem cells, and mammary epithelial cells. In addition, noncoding RNAs, named eRNAs, are synthesized at super-enhancer regions before their target genes are transcribed. Many functional studies revealed that super-enhancers and eRNAs are essential for the regulation of tissue-specific gene expression. In this review, we summarize recent findings concerning enhancer function in tissue-specific gene regulation and cancer development.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.13 no.5
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• pp.110-117
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• 2004

In automatic welding process using a robot, seam tracking is one of the important parts. Sensor for seam tracking is divided broadly into two categories as non contact sensor and contact sensor. The arc sensor is one of the non contact sensors, and it can be applied in weaving arc and rotating arc welding process. In such the arc sensors, rotating arc sensor can be applied to high speed welding over tens of Hz. The decrease of self regulation by high rotating speed causes to improve accuracy and response of sensor. In this study, fuzzy controller was used to track the seam for the $CO_2$ arc welding which had unstable arc. It could be shown that the rotating arc sensor was better than the weaving arc sensor.

• Proceedings of the KIEE Conference
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• 2002.07d
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• pp.2568-2571
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• 2002

A LCD backlight inverter control IC based on the piezoelectric transformer (PZT) for Cold Cathode Fluorescent Lamp (CCFL) lighting is proposed. It is indeed a variable frequency, variable duty (VFVD) controller having dual feedback control loops for achieving both the regulation of lamp current and the maximum efficiency. The PWM controller regulates the lamp current, while the PLL controller tunes the operating frequency to the frequency that the efficiency of the combined LC-PZT resonator becomes maximum. The mixed PLL/PWM control technique lets the backlight inverter operate at the maximum efficiency in spite of the variation of component and environment. The controller features include a protection for an open or broken lamps, and an open lamp regulation.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2005.04a
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• pp.190-190
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• 2005

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2005.04a
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• pp.109-109
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• 2005

• Journal of the Korean Society for Heat Treatment
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• v.21 no.2
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• pp.101-110
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• 2008

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 2002.05a
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• pp.111-119
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• 2002

• Environmental and Resource Economics Review
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• v.18 no.3
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• pp.523-544
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• 2009

The purpose of this paper is to estimate the impact of foreign direct investment on environmental performance for 27 OECD countries using endogenous environmental policy model. The empirical test shows that with 1% increase in the ratio of inflow stock of foreign direct investment over domestic capital stock, emission on NOx and $CO_2$ will increase by 0.0071%(NOx) and 0.0165%($CO_2$) and 1% increase in the ratio of foreign capital stock induces 0.044%(fixed effect) and 0.047%(random effect) of economic growth. 1% increase of per labor total output increases 2.038%(fixed effect) or 1.890%(random effect) in reinforcement of environmental regulation. However, we could not confirm the Porter's hypothesis that the more strong environmental regulation leads technical innovation. The scale effects (0.0119, 0.0172) are estimated higher than the technical effects (-0.0048, -0.0007) in two pollutants (NOx, $CO_2$). It implies that each country needs to increase pollution abatement and control expenditure more aggressively to protect environment.