• Proceedings of the Korean Magnestics Society Conference
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• 2017.05a
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• pp.151-151
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• 2017

• Proceedings of the Korean Magnestics Society Conference
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• 1998.10a
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• pp.76-77
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• 1998

• Proceedings of the Korean Magnestics Society Conference
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• 2000.09a
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• pp.512-513
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• 2000

• Proceedings of the Korean Magnestics Society Conference
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• 1999.10a
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• pp.44-45
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• 1999

• Proceedings of the Korean Magnestics Society Conference
• /
• 1999.10a
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• pp.110-111
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• 1999

• Proceedings of the Korean Magnestics Society Conference
• /
• 2016.05a
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• pp.81-82
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• 2016

• Proceedings of the Korean Magnestics Society Conference
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• 2016.11a
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• pp.55-55
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• 2016

• Journal of Pharmaceutical Investigation
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• v.32 no.2
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• pp.73-80
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• 2002

Cefuroxime axetil is a cephalosporin antibiotic having a high activity against a wide spectrum of Grampositive and Gram-negative microorganisms. It is a cephalosporin antibiotic which exist as 2 diastereoisomers: diastereoisomer A and B. It shows polymorphism of three forms: a crystalline form having a melting point of about $180^{\circ}C$, a substantially amorphous form having a high melting point of about $135^{\circ}C$ and a substantially amorphous form having a low melting point of about 70^{\circ}C$. The crystalline form of cefuroxime axetil is slightly soluble in water because diastereoisomer A has lower solubility than B in water. Substantially amorphous form of which there are no difference in solubility between diastereoisomer A and B has better solubility than crystalline form, but it forms a thicker gel than crystalline form upon contact with an aqueous medium. Based on this reason, cefuroxime axetil is not readily absorbable in the gastrointestinal tract, rendering its bioavailability on oral administration very low. The object of this study was to develop an improved non-crystalline cefuroxime axetil composition having a high physicochemical stability and bioavailability. A non-crystalline cefuroxime axetil solid dispersant showing no peak on a Differential Scanning Calorimetry (DSC) scan is prepared by dissolving cefuroxime axetil and a surfactant in an organic solvent; suspending a water-insoluble inorganic carrier in the resulting solution; and spray drying the resulting suspension to remove the organic solvent, said solid dispersant having an enhanced dissolution and stability of cefuroxime axetil and being useful for the preparation of a pharmaceutical composition for oral administration. Tablet was formulated with this cefuroxime axetil solid dispersant, disintegrants and other ingredients. It disintegrated and dissolved easily and dynamically in dissolution medium, so showed a good dissolution profile.

• Journal of Magnetics
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• v.5 no.3
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• pp.85-89
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• 2000

The hysteretic characteristics of giant magnetoimpedance (GMI) profiles have been measured in Co-based amorphous ribbon with various anisotropy angles $\theta_k$, and they have been analyzed by using the Stoner-Wohl-farth model. Two-peaks behavior with a dip near zero field is revealed in the measured GMI profile at 10 MHz irrespective of $\theta_k$. The negligible hysteresis of the field fur the dip is close to the calculation assuming the magnetization jump from a metastable to stable state. However, the hysteretic asymmetry far the angle range of $20^\circ\leq\theta_k < 60^\circ$ is well described by the divergence in the calculation without the magnetization jump. The asymmetry for $\theta_k\geq60^\circ$ may be due to the divergence, but the shapes of measured profiles are quite different from the calculations with single peak near zero field, indicating that Stoner-Wohlfarth model can be well used to describe GMI characteristics for the anisotropy angle range of $20^\circ\leq\theta_k < 60^\circ$at the frequency of 10 MHz in Co-based amorphous ribbons.

• Journal of the Korean Magnetics Society
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• v.4 no.2
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• pp.150-153
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• 1994

Magnetic field annealing method has been used to obtain proper hysteresis loop shapes which are useful to a device using amorphous ribbon. In this study, two pairs of Helmhotz coils were used to apply longitudinal and transverse magnetic field during annealing. For the measurement of coercive field strength noise which depends on magnetic field annealing, Co-based amorphous alloy ribbon $VITROVAC^{\circledR}$ 6030 was used. For the sample which was annealed under dc transverse and dc longitudinal magnetic field, coercive field strength noise was nearly independent of magnetizing frequency ranging from 1 to 100 kHz, but dc transverse and ac longitudinal magnetic fields annealed samples show that the coercive field strength noise decreased in power of magnetizing frequency. When magnetic domain nucleation occurred, the coercive field strength noise increased remarkably and decreased in power of magnetizing frequency.