• BMB Reports
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• 제51권12호
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• pp.609-610
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• 2018

Glycosylation is one form of protein modification and plays a key role in protein stability, function, signaling regulation and even cancer. NleB and SseK are bacterial effector proteins and possess glycosyltransferase activity, even though they have different substrate preferences. NleB/SseKs transfer the GlcNAc sugar to an arginine residue of host proteins, leading to reduced $NF-{\kappa}B-dependent$ responses. By combining X-ray crystallography, NMR, molecular dynamics, enzyme kinetic assays and in vivo experiments, we demonstrated that a conserved HEN (His-Glu-Asn) motif in the active site plays a key role in enzyme catalysis and virulence. The lid-domain regulates the opening and closing of the active site and the HLH domain determines the substrate specificity. Our findings provide evidence for the enzymatic mechanism by which arginine can be glycosylated by SseK/NleB enzymes.

• 한국기계기술학회지
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• 제20권6호
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• pp.865-871
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• 2018

The 3-way valve have been used as a valve for opening and closing the valve by the flow control in the pressure system of the cryogenic and high pressure environment. In this paper, numerical analysis and experimental study on fracture nipple of 3-way ultra high pressure valve applied to space launch vehicle was carried out. We have developed a 3-way valve numerical simulation modeler of cryogenic environment using commercial software ANSYS 18.2. As results of numerical analysis, optimum nipple condition was derived. In addition, a 3-way valve prototype was fabricated and the fracture test was performed and compared with the numerical analysis results.

• International Journal of Computer Science & Network Security
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• 제23권6호
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• pp.140-146
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• 2023

A detailed survey, applications and challenges of video encoding-decoding systems is discussed in this paper. A novel architecture has also been set aside for future work in the same direction. The literature reviews span the years 1960 to the present, highlighting the benchmark methods proposed by notable academics in the field of video compression. The timeline used to illustrate the review is divided into three sections. Classical methods, conventional heuristic methods, and current deep learning algorithms are all used for video compression in these categories. The milestone contributions are discussed for each category. The methods are summarized in various tables, along with their benefits and drawbacks. The summary also includes some comments regarding specific approaches. Existing studies' shortcomings are thoroughly described, allowing potential researchers to plot a course for future research. Finally, a closing note is made, as well as future work in the same direction.

• 한국산학기술학회논문지
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• 제17권5호
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• pp.364-371
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• 2016

본 논문에서는 차량이 주차된 지형의 조건에 따라 적용되는 도어 개폐 보조력 예측 모델을 제시하였다. 경사도, 사용자의 힘 등의 조건에 따른 개폐력 설정을 위하여 작동 보조력에 대한 학습 모델을 구현하여 비교하였고, 예측 모델의 학습을 위하여 축소모형을 제작하여 실험을 통해 학습데이터를 얻을 수 있는 실험 모델을 구성하였다. 실제 보상력 데이터를 학습, 반영하여 적정 값을 도출할 수 있는 학습 알고리즘을 개발하고, 이를 적용할 수 있는 시스템을 개발하였다. 학습 방법 중에서 인공신경망(Artificial Neural Network, ANN)과 서포트 벡터 머신(Support Vector Machine, SVM) 알고리즘을 적용하여 비교 검증하였다. 실제 측정값과 비교 검증한 결과, 차량의 도어 개폐 보조력 예측을 위해서 서포트 벡터 머신의 상대적으로 높은 적용성을 확인할 수 있었으며, 이 예측 모델을 활용하여 경사, 사용자의 힘에 따라 도어 개폐 구동 모터가 보상해야 할 적정한 힘을 예측하여 시간에 따라 구동함으로써 사용자가 평지와 같은 힘으로 문을 제어할 수 있는 시스템 구성을 제시하였다.

• 공학기술논문지
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• 제10권3호
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• pp.285-290
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• 2017

Molding of body with ribs is the most difficult during flow molding process. The rib area is easy to be deformed at the rear side due to wall thickness variation. In this study, relationships between molding condition and deflection of rib-shaped part is investigated during the compression molding of fiber reinforced plastic composites, and the following results are derived. Polypropylene(PP), Polystyrene(PS), and stampable sheet(SS 40wt%) show the increment of deflection along with releasing temperature. For the correlation between incremental holding pressure load and deflection, stampable sheet exhibits lower deflection along with higher holding pressure, while PS shows significant increase of deflection with higher holding pressure, PP shows completely different characteristic, significant reduction of deflection along with higher holding pressure. Regarding to mold temperature and deflection, deflection amount of SS is the biggest, and PS shows the smallest. In addition, all three kinds shows the highest amount of deflection at 173C. Deflection is reduced when mold closing speed is increased. Amount of deflection in SS is larger and is not highly dependent on molding conditions like holding pressure and cooling parameters, compared with single component material like PP. This can be elucidated by anisotropic and inhomogeneous characteristics of glass fiber during filling process of stampable sheet composite.

• Journal of Korean Neurosurgical Society
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• 제29권5호
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• pp.635-639
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• 2000

Objective : Surgery for the microvascular decompression is mostly concerned with injury to the cranial nerves or brain stem by cerebellar retraction. Intraopeartive brain stem auditory evoked potentials(BAEPs) has been continuously monitored on surgery to evaluate the extent of injury, recovery of the nerves and prognosis. Methods : Of the 161 cases of CP angle surgery from Feb. 1996 to Apr. 1998, 103 cases were monitored during operation. Thirty five patients who had undergone similar surgery were selected and evaluated ; 23 patients were monitored and 12 were not during surgery. If monitor showed more than 0.5 mSec delay of latency, surgeon was given a warning not to retract brain any more. If more than 1mSec delay, surgeon was informed to stop surgery and wait for the returning of evoked potentials. The level of amplitudes and delay of latencies during the initial stage of operation, opening the dura, insertion of teflon patches, and closing the dura and recovery were then compared. Resuls : Twenty patients were male and 15 were female. Their average age was 50.26 years. Mean amplitude during the initial stage of operation was $0.60{\pm}0.25mV$, at opening the dura $0.56{\pm}0.26$, after teflon patches insertion $0.49{\pm}0.20$, and after closure of dura $0.47{\pm}0.28mV$. Mean latency during the early stage of operation was $6.08{\pm}0.67mSec$, at opening of dura $6.38{\pm}0.55$, insertion of teflon $6.97{\pm}0.59$, and closing the dura $6.17{\pm}0.54$. There was statistical significance in the difference of amplitudes between each procedures, and in the difference of latencies. For the complete recovery of amplitude and latency, it usually took average 5.65 minutes(0-20 min). In monitored group, only one patient required more than 20 minutes to recover and suffered from hearing disturbance after surgery. Others were recovered within 10 minutes without complications. However, 4 out of 12 patients who were not monitored showed hearing disturbance, and 1 patient had temporary facial palsy and dizziness(p＝0.000). Conclusion : The results indicate that continuous intraoperative monitoring of BAEPs during CP angle surgery is seen mandatory procedure to prevent operative complications.

• 대한치과교정학회지
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• 제27권5호
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• pp.801-813
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• 1997

정상교합자와 골격성 III급 부정교합자의 저작운동형태를 비교연구하기위해서 30명의 정상교합자와 20명의 골격성 III급 부정교합자를 대상으로 츄잉검을 사용하고 BioPAK system을 이용하여 전두면상에서 저작운동을 기록, 분석하였다. 각 개체마다 대표하는 저작경로를 정하여 저작폭경, 개구거리, 개구각, 페구각, 최대개구속도, 최대폐구속도를 알아보았다. 또 저작경로의 형태에 따라 특징적인 7가지 패턴으로 분류하여 다음의 결과를 얻었다. 1. 정상교합자군에 비해 골격성 III급 부정교합자군에서는 좀 더 다양하고 수직적인 저작양상을 나타내었다. 2. 저작폭경의 비교에서는 골격성 III급 부정교합자군이 정상교합자군에 비해 더 좁게 나타났다(p<0.01) 3. 개구거리에서는 골격성 III급 부정교합자군이 정상교합자군에 비해 더 작게 나타났으나 통계학적으로 유의성은 없었다(p>0.05). 4. 개구각과 폐구각에서는 골격성 III급 부정교합자군에서 정상교합자군보다 더욱 예각으로 나타났다(p<0.01). 5. 최대개구속도, 최대폐구속도에서는 정상교합자군에 비해 골격성 III급 부정교합자군에서 느리게 나타났으나 통계학적으로 유의성은 없었다(p>0.05). 6. 저작운동형태에 따른 분류에서 정상교합자군에서는 Type II가 73.4%로 가장 많은 비율을 차지하였으나, 골격성 III 급 부정교합자군에서는 Type III가 35.0%, Type II가 30.0%로 많은 비율을 차지하였다. 7. 저작운동형 태에 따른 분류에서 골격성 III급 부정교합자군에서는 Type IV(chopping type)가 25.0%로 정상교합자군 3.3%에 비해 많은 비율을 차지하였다.

• Journal of Oral Medicine and Pain
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• 제11권1호
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• pp.19-27
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• 1986

Registration of the mandibular movement in patients with temporomandibular joint noise (clicking and/or crepitus) was performed using one of mandibular tracking devices(SAPHON VISI-TRAINER CII,Tokyo Shizai-sha Inc.,Japan). The obtained results were follows : 1. In many cases, the movement pattern of light emitting diode(LED) attached on the mandibular midline showed lateral deviation from a vertical reference line which was pronounced in association with TMJ noise during opening and closing. 2. In patients with unilateral TMJ noise the mandibular midline usually towards the side demonstrating TMJ noise during opening. 3. A distinct V-shaped discontinuity in the trace of velocity of mandibular movement was found at the point of the TMJ noise. 4. In patients with TMJ noise the velocity of mandibular movement at the point of the TMJ noise was decreased rapidly. 5. In several cases, TMJ noise could be eliminated by traning of Rocabado`s control of TMJ rotations.

• 동력기계공학회지
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• 제20권3호
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• pp.57-63
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• 2016

This paper presents the experimental result and theoretical analysis result to investigate the correlation between the operating force, angle and locking torque for vehicle hood frame. Also, we derived the experimental equation that using the results for experiment and theory. The hood frame is switching-devices used for opening and closing the vehicle hood. It needs the correlation data between locking torques of each joint, operating force and angle of hood frame. The correlation data for torque and reaction force of hood frame obtained through experiment and theory analysis. Finally, the experimental equation of the locking torque prediction for the hood frame is derived.

• 동력기계공학회지
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• 제17권2호
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• pp.103-107
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• 2013

The structure of a variable liquid column oscillator(a VLCO) is analogous to that of the tuned liquid column damper used to suppress oscillatory motion in large structures like tall buildings and cargo ships. The VLCO is a system absorbing high kinetic energy of accelerated motions of multiple floating bodies in the effect of air springs occurred by installation of inner air chambers. Thus, VLCO can improve the efficiency of energy than wave energy converters of the activating object type made in Pelamis Company. In this research, the experiment was performed that a simple floating body was filled with internal fluid of same draft. The characteristics of motions were evaluated in each case of the opening or closing of the upper valves.