• BMB Reports
• /
• v.51 no.12
• /
• pp.609-610
• /
• 2018

Glycosylation is one form of protein modification and plays a key role in protein stability, function, signaling regulation and even cancer. NleB and SseK are bacterial effector proteins and possess glycosyltransferase activity, even though they have different substrate preferences. NleB/SseKs transfer the GlcNAc sugar to an arginine residue of host proteins, leading to reduced $NF-{\kappa}B-dependent$ responses. By combining X-ray crystallography, NMR, molecular dynamics, enzyme kinetic assays and in vivo experiments, we demonstrated that a conserved HEN (His-Glu-Asn) motif in the active site plays a key role in enzyme catalysis and virulence. The lid-domain regulates the opening and closing of the active site and the HLH domain determines the substrate specificity. Our findings provide evidence for the enzymatic mechanism by which arginine can be glycosylated by SseK/NleB enzymes.

• Journal of the Korean Society of Mechanical Technology
• /
• v.20 no.6
• /
• pp.865-871
• /
• 2018

The 3-way valve have been used as a valve for opening and closing the valve by the flow control in the pressure system of the cryogenic and high pressure environment. In this paper, numerical analysis and experimental study on fracture nipple of 3-way ultra high pressure valve applied to space launch vehicle was carried out. We have developed a 3-way valve numerical simulation modeler of cryogenic environment using commercial software ANSYS 18.2. As results of numerical analysis, optimum nipple condition was derived. In addition, a 3-way valve prototype was fabricated and the fracture test was performed and compared with the numerical analysis results.

• International Journal of Computer Science & Network Security
• /
• v.23 no.6
• /
• pp.140-146
• /
• 2023

A detailed survey, applications and challenges of video encoding-decoding systems is discussed in this paper. A novel architecture has also been set aside for future work in the same direction. The literature reviews span the years 1960 to the present, highlighting the benchmark methods proposed by notable academics in the field of video compression. The timeline used to illustrate the review is divided into three sections. Classical methods, conventional heuristic methods, and current deep learning algorithms are all used for video compression in these categories. The milestone contributions are discussed for each category. The methods are summarized in various tables, along with their benefits and drawbacks. The summary also includes some comments regarding specific approaches. Existing studies' shortcomings are thoroughly described, allowing potential researchers to plot a course for future research. Finally, a closing note is made, as well as future work in the same direction.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.5
• /
• pp.364-371
• /
• 2016

We developed a prediction model of assistance force for the opening/closing of an automobile door depending on the condition of the parking ground. The candidates of the learning models for the operating assistance force were compared to determine the proper force according to the slope and user's force, etc. The reduced experimental model was developed to obtain learning data for the estimation model. The learning algorithm was composed to predict the assistance force to incorporate real assistance force data. Among these algorithms, an Artificial Neural Network (ANN) and Support Vector Machine(SVM) were applied and the adaptability was compared between these models. The SVM provided more adaptability for the learning process of the door assistance force prediction. This paper proposes a system for determining the assistance force to control a door motor to compensate for the deviation of required door force in the slope condition, as needed in the plane condition.

• Journal of Advanced Engineering and Technology
• /
• v.10 no.3
• /
• pp.285-290
• /
• 2017

Molding of body with ribs is the most difficult during flow molding process. The rib area is easy to be deformed at the rear side due to wall thickness variation. In this study, relationships between molding condition and deflection of rib-shaped part is investigated during the compression molding of fiber reinforced plastic composites, and the following results are derived. Polypropylene(PP), Polystyrene(PS), and stampable sheet(SS 40wt%) show the increment of deflection along with releasing temperature. For the correlation between incremental holding pressure load and deflection, stampable sheet exhibits lower deflection along with higher holding pressure, while PS shows significant increase of deflection with higher holding pressure, PP shows completely different characteristic, significant reduction of deflection along with higher holding pressure. Regarding to mold temperature and deflection, deflection amount of SS is the biggest, and PS shows the smallest. In addition, all three kinds shows the highest amount of deflection at 173C. Deflection is reduced when mold closing speed is increased. Amount of deflection in SS is larger and is not highly dependent on molding conditions like holding pressure and cooling parameters, compared with single component material like PP. This can be elucidated by anisotropic and inhomogeneous characteristics of glass fiber during filling process of stampable sheet composite.

• Journal of Korean Neurosurgical Society
• /
• v.29 no.5
• /
• pp.635-639
• /
• 2000

Objective : Surgery for the microvascular decompression is mostly concerned with injury to the cranial nerves or brain stem by cerebellar retraction. Intraopeartive brain stem auditory evoked potentials(BAEPs) has been continuously monitored on surgery to evaluate the extent of injury, recovery of the nerves and prognosis. Methods : Of the 161 cases of CP angle surgery from Feb. 1996 to Apr. 1998, 103 cases were monitored during operation. Thirty five patients who had undergone similar surgery were selected and evaluated ; 23 patients were monitored and 12 were not during surgery. If monitor showed more than 0.5 mSec delay of latency, surgeon was given a warning not to retract brain any more. If more than 1mSec delay, surgeon was informed to stop surgery and wait for the returning of evoked potentials. The level of amplitudes and delay of latencies during the initial stage of operation, opening the dura, insertion of teflon patches, and closing the dura and recovery were then compared. Resuls : Twenty patients were male and 15 were female. Their average age was 50.26 years. Mean amplitude during the initial stage of operation was $0.60{\pm}0.25mV$, at opening the dura $0.56{\pm}0.26$, after teflon patches insertion $0.49{\pm}0.20$, and after closure of dura $0.47{\pm}0.28mV$. Mean latency during the early stage of operation was $6.08{\pm}0.67mSec$, at opening of dura $6.38{\pm}0.55$, insertion of teflon $6.97{\pm}0.59$, and closing the dura $6.17{\pm}0.54$. There was statistical significance in the difference of amplitudes between each procedures, and in the difference of latencies. For the complete recovery of amplitude and latency, it usually took average 5.65 minutes(0-20 min). In monitored group, only one patient required more than 20 minutes to recover and suffered from hearing disturbance after surgery. Others were recovered within 10 minutes without complications. However, 4 out of 12 patients who were not monitored showed hearing disturbance, and 1 patient had temporary facial palsy and dizziness(p＝0.000). Conclusion : The results indicate that continuous intraoperative monitoring of BAEPs during CP angle surgery is seen mandatory procedure to prevent operative complications.

• The korean journal of orthodontics
• /
• v.27 no.5 s.64
• /
• pp.801-813
• /
• 1997

A comparative study was made on the chewing movements of normal occlusion and skeletal class m malocclusion. Thirty normal occlusion subjects and twenty skeletal class III malocclusion patients were given chewing gums for the study : using BioPAK system, the chewing movement on the frontal plane was recorded and analyzed. With a typical chewing path chosen representing each subject, chewing width, opening distance, opening and closing angles, maximum opening and closing velocities were observed. Seven characteristic patterns were classified based on the types of chewing paths. The followings are the results : 1. Compared with the normal occlusion group, the skeletal class III malocclusion group showed more varied and vertical chewing patterns. 2. In comparision of chewing widths, skeletal class m malocclusion group showed narrower path than the normal occlusion group(p<0.01). 3. In opening distance, skeletal class III malocclusion group appeared shorter than the normal occlusion group without statistical significance(p>0.05). 4. In opening and closing angles, skeletal class III malocclusion group showed more acute angles than the normal occlusion group(p<0.01). 5. In maximum opening and closing velocities, skeletal class III malocclusion group was slower than the normal occlusion group but with no statistical significance(P>0.05). 6. In the classification of chewing movement pattern, the normal occlusion group had Type II as the highest rate at 73.4% ; in skeletal class III malocclusion group, the highest rate was Type III at 35.0%, followed by Type II at 30.0% 7. In the classification of chewing movement pattern, Type IV(chopping type)of skeletal class III malocclusion group showed a higher rate with 25.0% over 3.3% of normal occlusion group.

• Journal of Oral Medicine and Pain
• /
• v.11 no.1
• /
• pp.19-27
• /
• 1986

Registration of the mandibular movement in patients with temporomandibular joint noise (clicking and/or crepitus) was performed using one of mandibular tracking devices(SAPHON VISI-TRAINER CII,Tokyo Shizai-sha Inc.,Japan). The obtained results were follows : 1. In many cases, the movement pattern of light emitting diode(LED) attached on the mandibular midline showed lateral deviation from a vertical reference line which was pronounced in association with TMJ noise during opening and closing. 2. In patients with unilateral TMJ noise the mandibular midline usually towards the side demonstrating TMJ noise during opening. 3. A distinct V-shaped discontinuity in the trace of velocity of mandibular movement was found at the point of the TMJ noise. 4. In patients with TMJ noise the velocity of mandibular movement at the point of the TMJ noise was decreased rapidly. 5. In several cases, TMJ noise could be eliminated by traning of Rocabado`s control of TMJ rotations.

• Journal of Power System Engineering
• /
• v.20 no.3
• /
• pp.57-63
• /
• 2016

This paper presents the experimental result and theoretical analysis result to investigate the correlation between the operating force, angle and locking torque for vehicle hood frame. Also, we derived the experimental equation that using the results for experiment and theory. The hood frame is switching-devices used for opening and closing the vehicle hood. It needs the correlation data between locking torques of each joint, operating force and angle of hood frame. The correlation data for torque and reaction force of hood frame obtained through experiment and theory analysis. Finally, the experimental equation of the locking torque prediction for the hood frame is derived.

• Journal of Power System Engineering
• /
• v.17 no.2
• /
• pp.103-107
• /
• 2013

The structure of a variable liquid column oscillator(a VLCO) is analogous to that of the tuned liquid column damper used to suppress oscillatory motion in large structures like tall buildings and cargo ships. The VLCO is a system absorbing high kinetic energy of accelerated motions of multiple floating bodies in the effect of air springs occurred by installation of inner air chambers. Thus, VLCO can improve the efficiency of energy than wave energy converters of the activating object type made in Pelamis Company. In this research, the experiment was performed that a simple floating body was filled with internal fluid of same draft. The characteristics of motions were evaluated in each case of the opening or closing of the upper valves.