• Title/Summary/Keyword: Clo

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The Effect of 2-Week Dual Therapy with Proton Pump Inhibitor and Amoxicillin in the Eradication of Helicobacter pylori Infection for Treatment of Children with Recurrent Abdominal Pain (만성 반복성 복통 환아에서 Helicobacter pylori 감염에 대한 Proton Pump Inhibitor 및 Amoxicillin 2주 치료 효과)

  • Lee, Young-Mock;Lee, Chang-Han;Chung, Ki-Sup
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.3 no.1
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    • pp.23-29
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    • 2000
  • Purpose: It has recently been recognized that Helicobacter pylori (H. pylori) is an important factor in the pathogenesis of recurrent abdominal pain (RAP) in children. But, the best treatment for H. pylori infection is still unsettled. This study was performed to evaluate the efficacy of 2 weeks dual therapy with proton pump inhibitor (PPI) and amoxicillin for children with H. pylori infection associated with RAP. Method: Our study included 24 children with RAP who were H. pylori positive assessed by CLO test and histologic examination (silver stain). We used the regimen consisted of PPI (omeprazole, 0.7 mg/kg/day) and amoxicillin (50 mg/kg/day) for 2 weeks to eradicate H. pylori. Eradication of H. pylori was determined 4 weeks after the termination of treatment using the CLO test and histologic examination. Results: The endoscopic diagnoses of patients were nodular gastritis in 11 cases, superficial gastritis in 7 cases, peptic ulcer in 4 cases and normal finding in 2 cases. H. pylori was eradicated in 12 cases by omeprazole and amoxicillin dual therapy for 2 weeks and the eradication rate was 50%. In 4 of 12 children in whom H. pylori had not been eradicated with that regimen, we successfully eradicated H. pylori with other regimens of which 2 or 3 drugs among omeprazole, amoxicillin, clarithromycin, colloidal bismuth subcitrate ($Denol^{(R)}$) and metronidazole were used. Conclusion: The dual therapy with PPI and amoxicillin for 2 weeks had no clear advantage over other regimens for the eradication of H. pylori infection in children. We concluded that the combi-nation of PPI and amoxicillin for 2 weeks is not so good for H. pylori eradication as other commonly used regimens.

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Effect of One- or Two-Week Triple Therapy with Omeprazole, Amoxicillin, and Clarithromycin on Eradication of Helicobacter pylori Infection in Children (소아에서 Omeprazole, Amoxicillin, Clarithromycin 삼제 병합 요법의 치료기간별 Helicobacter pylori 제균율)

  • Choi, In-Kyoung;Lee, Seung-Yun;Chung, Ki-Sup
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.5 no.1
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    • pp.19-25
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    • 2002
  • Purpose: The triple therapy with proton pump inhibitor (PPI) has been recognized as the treatment of choice in Helicobacter pylori (H. pylori) infection in adults. However, the effect of triple therapy with omeprazole, amoxicillin and clarithromycin (OAC) on eradication of H. pylori infection in children has not been established yet. This study was performed to evaluate the efficacy of OAC triple therapy and to compare the effect of one-week with two-week therapy on H. pylori eradication. Methods: From July 1998 to July 2000, 34 children with upper gastrointestinal symptoms, who underwent upper gastrointestinal endoscopy with biopsy at entry and 4 or more weeks after therapy, were enrolled in this study. H. pylori infection was assessed by CLO test and histologic examination (Hematoxylin-Eosin stain or Alcian yellow stain) with biopsy specimens. The regimen consisted of omeprazole (0.7 mg/kg/day), amoxicillin (50 mg/kg/day), and clarithromycin (25 mg/kg/day) for 1 week (n=21) or 2 weeks (n=13). Eradication of H. pylori was determined after the termination of treatment by the CLO test and histologic examination. Results: One-week treatment group consisted of 21 children (11 male, 10 female) with a mean age of $9.5{\pm}3.0$ years. Two-week group consisted of 13 children (4 male, 9 female) with a mean age of $9.9{\pm}4.0$ years. The endoscopic diagnoses included nodular gastritis in 19 cases, superficial gastritis in 7 cases, gastric ulcer in 4 cases, purpuric duodenitis in 2 cases, and normal in 2 cases. H. pylori was eradicated in 28 of total 34 children (82.4%). In 1-week group, H. pylori was eradicated in 17 of 21 children (81%). In 2-week group, H. pylori was eradicated in 11 of 13 children (84.6%). In remaining 6 cases in whom H. pylori had not been eradicated with OAC regimen, H. pylori infection persisted despite of the treatment with additional drugs such as colloidal bismuth subcitrate ($Denol^{(R)}$) and metronidazole. Conclusion: In this study, eradication rate of H. pylori with OAC regimen was 82.4%, and the triple therapy would be highly effective as primary treatment. However, there was no significant difference in the eradication rate between the 1-week and 2-week treatment group (P=0.785).

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The Effect of Adjustable Garment Closures and Layering on Insulation in Cold Weather

  • Kim, Chil-Soon;McCullough, Elizabeth
    • Fashion & Textile Research Journal
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    • v.3 no.5
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    • pp.479-485
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    • 2001
  • This study was to determine the effect of garment closures and layering systems on insulation, using a thermal movable manikin in cold weather conditions. The insulation values of ensembles with opened and closed features were measured, and those of four different layered clothing ensembles were tested while standing and while walking. Our research indicated that when there was an opening involved in design the system, insulation decreased; even a zip-out lining in the armpit affected little. If a light weight jacket and pants are put on over a fleece shirt and pants instead polyester underwear, the amount of insulation increase was 0.43 clo.

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Effects of relative humidity on comfort sensation by comparison between the young and the aged (여름철 냉방시 상대습도가 쾌적감에 미치는 영향(청년과 고령자의 비교를 중심으로))

  • 김동규;금종수;최광환;박희욱;김종열;주익성
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.10 no.4
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    • pp.381-388
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    • 1998
  • Hot and humid weather in summer generally brings about discomfort. Experiments on which relative humidity makes effects on the comfort sensation were performed to the young and the aged using sensation vote. From July to October 1996, seven college students and eleven aged people were exposed for 2 hours under six different conditions in the Pukyong National University test chamber so as to determine the effects of relative humidity on thermal and comfort sensations. Subjects were wearing same clothes, and the mean clo value was 0.5. The mean radiant temperature was equal to the air temperature and air velocity in the occupied zone around 0.lm/s. In the experiments, it was found that discomfort could be largely reduced when the humidity is controlled to low values in the settled high temperature.

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A Study on the Variation of Physiology Signals based on EEG with Humidity (습도 변화에 따른 뇌파 기반 생체신호 변화에 관한 연구)

  • Kim, Myung-Ho;Kim, Jung-Min
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.62 no.1
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    • pp.50-55
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    • 2013
  • Subjects with 0.7[clo]'s amount of clothing were estimated on their thermal comfort, concentrativeness, heart rate variability, stress and fatigue degree when given variation in relative humidity to 30, 40, 50, 60, 70, and 80[RH%], in an environmental test room of temperature 25[$^{\circ}C$], illumination 1000[lux] and air velocity 0.02[m/sec], by using EEG, learning ability and HRV. At the result, it was at 50~60[RH%] of relative humidity that subject's thermal comfort and concentrativeness were at the highest while stress were at the lowest, and it was at 60[RH%] of relative humidity that heart rate variability was most stabilized. It was found that when temperature and humidity of the environmental test room are at 25[$^{\circ}C$] and 50~60[RH%], subject's productivity and psychological state are least affected.

Experimental Study on Thermal Comfort Sensation and Physiological Responses of Koreans in various Thermal Conditions Part IV : Effects of Draft on Thermal Comfor in convection Heating (한국인의 온열쾌적감 및 생리신호에 관한 연구 Part IV : 대류난방시 Draft가 온열쾌적감에 미치는 영향)

  • 김동규;최호선;이기섭;금종수;최광환;배동석;이구형
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 1998.11a
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    • pp.116-120
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    • 1998
  • 난방.공조공간에서는 강한 기류가 Draft를 유발한다. Draft라 함은 인체가 기류(Air Movement)에 의해 원하지 않은 국부적인 냉각효과를 받는 것을 말한다(ASHRAE). 본 연구에서는 피험자의 체감실험을 통해 겨울철 대류난방시 실온 설정조건에 대한 기류속도의 허용범위을 찾고자 .하였다. 피험자는 일정 유니폼을 착용하고 의자에 앉은 상태로 실온 18.21.24$^{\circ}C$, 풍속 0.15.0.3.0.45m/s의 조건에서 기류감, 온냉감, 쾌불쾌감을 신고하였다. 실험시 착의량은 남자 0.7, 여자 1.0 clo이었으며, 실온이 21$^{\circ}C$일 때는 기류속도 0.15m/s까지, 실온이 24$^{\circ}C$일 때는 기류속도 0.3m/s까지 허용범위에 포함되었다.

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Detachable Liner and Insulation of Outdoor Clothing (착탈식 라인어와 아웃도어 의복의 보온성)

  • Kim, Chil-Soon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.26 no.12
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    • pp.1756-1764
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    • 2002
  • 본 연구의 목적은 의복시스템 내 에서 착탈이 가능한 라이너 가 있을 때 얼마만큼의 보온성 이 증가되는가를 알고자 하는 것이다. 서로 다른 섬유조성 과 두께를 가지는 3개 의 의복앙상블을 선정하여 움직일 수 있는 마네킨을 사용하여 14$^{\circ}C$로 조절되어 있는 인공기후실에서 보온성을 측정하였다. 그 결과 라이너 사용 후 보온성이 증가되었는데 그 정도는 라이너 의 두께 와 섬유조성에 따라서 다르며 약 0.5 clo 증가하였다. 이 결과로부터 착탈 가능한 라이너의 사용으로 추운기후에 어느 정도 적응 할 수 있는가를 확인할 수 있었다.

Computer Simulation for Calculation of Thermal Insulation in Korean Folk Clothes (한복의 보온력 평가를 위한 컴퓨터 시뮬레이션)

  • 권오경;성수광
    • Journal of the Korean Society of Clothing and Textiles
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    • v.21 no.7
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    • pp.1153-1161
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    • 1997
  • The insulation provided by clothing system is usually expressed in terms of a coo units and its distribution of the body, directly affect convective, conductive, and radiant heat loss from the skin to the environment Evaporated heat loss is dependent upon fabric permeability, the amount of body surface area covered by clothing, and the pumping of air between the body and garment layers. Persons at low to medium activity levels, dressed in conventional apparel in door environments, usually do not lose a large amount of heat through evaporation. Thermal manikin technology is used to measure the resistance to heat transfer provided by clothing systems. The reciprocal of this value, 6.45 W/m2.$^{\circ}C$ is often used in calculations for convenience. The purpose of this study was to implement a research program for calculation the insulation value (clo), body surface area and basal metabolic rate of selected clothing system. The project provided for the building of an insulation data base for use in evaluating and comparing new and improved garments.

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Thermal Environment and Heating Regulation System of the Co-Generation Apartment (열병합발전 아파트의 난방조절방식과 온열환경)

  • 윤정숙
    • Journal of the Korean Home Economics Association
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    • v.30 no.3
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    • pp.131-140
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    • 1992
  • The purpose of this study was to investigate the heating regulation systems and the thermal environment of the Co-Generation apartment house in winter. Personal self-administration and interview method were used in the survey of this study. The respondents were 352 housewives who resided in Mokdong apartement using Co-Generation heating systems. Data was analyzed using SPSS PC+ computer package. The results of this study were summarised as follow; The typical patterns of heating regulation systems were intermittent and partial heating in the living room and bedroom exclusive of kitchen area. The present condition of the thermal environment were relatively warm in winter and Heatng regulation systems were influenced by type of location. Determinants of the thermal sensation and thermal comfort were the type of location of apartment as a architectural factor, clo as a personal factor.

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유기 Hectorite Gel의 Rheology에 미치는 극성연가제에 관한 연구

  • 김창규
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.10 no.1
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    • pp.49-74
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    • 1984
  • Rheology of gels prepared with stearyl dimethyl benzyl ammonium hectorite (SDBAH) and various polar additives in n-butyl acetate was investigated by measuring the viscosity and rheogram. Including generally recognized polar additives, additional studies on the rheogram and viscosity were made with ether-type methyl cellosolve and carbitol, with dimethyl sulfoxide (DMSO) having sulfonyl group, and furthermore with above-mentioned polar additives containing small quantity of water, It was observed that molecular size, dipole moments and dielectric constants of polar additives had a great influence on viscosity increase and rheology of SDBAH gel, and the increase of SDBAH interlayer spacing was important factor in gel formation and viscosity change. It was also shown that thixotropy effect was increased with the increase of polar additive concentration, finally changed to rheopexy from thixotropy as the concentration of polar additives was increased more than about 40% of SDBAH weight. In addition thixotropy changed to rheopexy as the increase of shear rate. It was further found that the aqueous solutions of polar additives (water content, 5-25%) had more effects on rheology than additives without water, and particularly 95clo DMSO solution was the most effective. And the optimum concentration of polar additives showing maximum viscosity in the same SDBAH concentration system was examined.

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