• 제목/요약/키워드: Clinical investigation

검색결과 1,276건 처리시간 0.022초

맥진의 현대적인 객관화 연구를 위한 기반조사 - I. 기계적 측정법에 대한 비교연구- (The basic investigation for the objective study on the pulsation)

  • 김경철;신순식;강희정;처철용
    • 동의생리병리학회지
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    • 제17권5호
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    • pp.1147-1150
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    • 2003
  • Modern Objectification of Pulse Diagnosis, One of the Four Diagnosis Method of Oriental Medicine, is necessarily project to improving Oriental medical clinic status and quality by standardization of diagnosis database. At that, accurate measurement equipment or devices(sensor, system and instruments, etc,) to exactly detect MacSang(脈診 : the parameter and subject of pulse diagnosis) have not developed yet. Existing Pulse diagnosis devices are not satisfy clinical needs and medical equipments quality. We study for pulse diagnosis system, that CD is satisfying oriental medical clinic needs, is ensuring accuracy and reappearance to support in clinical diagnosis and treatment, is guaranteeing the quality of medical equipments. theoretical base and convenience.

흉요추 신경근병증으로 발현된 수막암종증 1예 (A Case of Leptomeningeal Metastasis Presented with Thoracolumbar Radiculopathy)

  • 민지원;이지현;김민정;유봉구
    • Annals of Clinical Neurophysiology
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    • 제7권1호
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    • pp.22-24
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    • 2005
  • We report a case of thoracolumbar radiculopathy presented with first symptom of leptomeningeal metastasis. A 65-year old man with non-Hodgkins lymphoma with complete remission was referred for further investigation of dull pain and numbness of right lower quadrant of abdomen. Electromyogram revealed right thoracolumbar radiculopathy. After two weeks, he complained severe continuous bilateral frontal dull headache. An examination of the cerebrospinal fluid revealed malignant lymphoid cells. We would like to emphasize that radiculopathy sometimes presents with first symptom of leptomeningeal metastasis.

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Clinical Investigation in Effect of Riboflavin Sodium Phosphate on Prevention and Treatment for Patients with Radiotherapy Related Esophagitis

  • Shen, Kang;Huang, Xin-En
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권4호
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    • pp.1525-1527
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    • 2015
  • Objective: To investigate the clinical effect of riboflavin sodium phosphate on prevention of radiotherapy related esophagitis (RRE). Methods: This retrospective study involved 55 patients with middle and advanced esophageal cancer who were divided into an experimental group of 28 and a control group of 27 patients. Those in the experimental group were treated with riboflavin sodium phosphate combined with conventional symptomatic treatment during radiotherapy; while patients in control group received the latter alone. The incidence and degree of RRE were compared after radiotherapy. Results: The incidences of RRE in experimental and control group were 53.5% and 81.4%, respectively (p<0.05); the incidence of stages III and IV RRE in the experimental group was 17.8%, while in the control group it was 44.4% (p<0.05). Conclusion: Riboflavin sodium phosphate could significantly prevent RRE and reduce the incidence of stage III and IV disease. These results were worthy of further confirmation by randomized controlled trials.

간질의 평가와 진단 - 발작간 뇌파소견을 중심으로 - (Interictal EEG in Diagnosis and Assessment of Epilepsy)

  • 박건우
    • 생물정신의학
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    • 제8권2호
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    • pp.233-238
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    • 2001
  • The routine interictal electroencephalogram(EEG) continues to play an important role in the diagnosis and treatment of epilepsy. The clinical investigation of brain disease in the last decade has been marked by dramatic advances in functional imaging, magnetic resonance scanning and digitized EEG. Epilepsy is a disorder of electrical hyperirritability of cerebral cortex and the interictal EEG remains the most convenient means available to demonstrate cortical hyperirritability. The sensitivity and specificity of the EEG in the diagnosis of epilepsy have been disputed. In this review, the type of EEG findings in epilepsy are reviewed and the sensitivity and specificity of interictal epileptiform discharge are discussed. And also the role of EEG in various clinical situations are summarized.

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간질환(肝疾患)과 혈청효소(血淸酵素) (Serum Enzyme in Hepatic Disease)

  • 김원근
    • 보험의학회지
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    • 제3권1호
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    • pp.142-148
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    • 1986
  • Liver is an oragan which has various functions. For this functions in liver disease change variously, many methods of examination of them are invented. Each liver disease impairs these functions diversly rather than uniformly, thus it is possible to differentiate each disease by using various methods of testing it. Liver has high reproductive capacity and despite partial impairment of its function localized disease may not show any abnormality in liver function test due to compensation of remaining intact tissue of the liver. Thus the result of liver function test should be interpreted under adequate clinical investigation with other test, not depending on the liver function test only. This thesis deals with the composition, distribution in living body and clinical significance of liberating enzyme, GOT, GPT, and LDH which are included in serum enzyme that show abnormality in liver disease.

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소아에서 원인불명열의 진단적 접근 - 감염성 질환을 위주로 하여- (Diagnostic approach to the fever of unknown origin in children - Emphasis on the infectious diseases -)

  • 최은화
    • Clinical and Experimental Pediatrics
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    • 제50권2호
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    • pp.127-131
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    • 2007
  • Fever of unknown origin (FUO) has been a convenient term used to classify patients who warrant a particular systemic approach to diagnostic evaluation and management. The greatest clinical concern in evaluating FUO is identifying patients whose fever has a serious or life-threatening cause when a delay in diagnosis could jeopardize successful intervention. Thorough history and complete physical examination are critical to uncover the etiologic diagnosis. Most cases of FUO in children are caused by atypical presentations of common diseases rather than by typical manifestations of rare disorders. Selection of diagnostic tests and speed of investigation should be guided by a knowledge of the disease severity, patient age, epidemiologic and geographic information, and any positive findings from a detailed history and physical examination. The three most common causes of FUO in children are infectious diseases, connective tissue diseases, and malignancy. In general, the prognosis of FUO in children is better than that of adults. Although the outcome is dependent on the primary disease process, fever abates spontaneously in most cases in whom the cause of fever remains unclear.

백부근(百部根)에 관(關)한 문헌적(文獻的) 고찰(考察) (효능(效能) 및 약리작용(藥理作用)을 중심(中心)으로) (Study of Literature on RADIX STEMONAE(Investigation of efficacy and pharmacological action on RADIX STEMONAE))

  • 최해윤;김종대
    • 대한한의학방제학회지
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    • 제7권1호
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    • pp.65-76
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    • 1999
  • According to the study of literature on RADIX STEMONAE about its efficacy, pharmacological action, and clinical adaptive disease, the results are as follows; 1. About the efficacy of RADIX STEMONAE, it is known as moistening the lungs to arrest cough, and intestinal parasites from ancient to now, and dispelling phlegm is also known. 2. The clinical adaptation of RADIX STEMONAE is chronic bronchitis, pertussis, pulmonary tuberculosis in respiratory disease, and ascaricide for Ascaris, Enterobius vermicularis or eczema, pruritus, destroy louse for endermic liniment. 3. The pharmacological action of RADIX STEMONAE are antitussive, tuberculostatic, anthelmintic, antibacterial, antivirus, antifungal. 4. The antitussive mechanism of RADIX STEMONAE is central inhibitor for cough center of medulla oblongata, and the mechanisms of bronchial smooth muscle relax, and expectorant is also known.

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사르코이드증에 동반된 다발신경병증 (Sensorimotor Polyneuropathy Associated with Sarcoidosis)

  • 안석원;김동욱;홍윤호;이광우
    • Annals of Clinical Neurophysiology
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    • 제5권1호
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    • pp.39-41
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    • 2003
  • Sarcoidosis is a multisystemic granulomatous disease of unknown etiology ogenesis, and most frequently presented with bilateral hilar lymphadenopathy, pulmonary infiltration, skin and eye lesion. However, neurological involvement including peripheral neuropathy is relatively rare. We report a patient who had sensorimotor polyneuropathy without other systemic symptoms or organ involvements frequently reported in sarcoidosis. Laboratory investigation suggestive of sarcoidosis lead to sural nerve biopsy for confirmation, which demonstrated noncaseating granulomatous changes. Sarcoidosis shoud be included in the differential diagnosis in subacute polyneuropathy even if there is no usual symptoms or signs suggestive of the systemic disease.

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피부조직검사: 소신경섬유 평가의 유용한 방법 (Skin Biopsy: Emerging Method for Small Nerve Fiber Evaluation)

  • 손은희
    • Annals of Clinical Neurophysiology
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    • 제17권2호
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    • pp.53-60
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    • 2015
  • Skin biopsy with investigation of small nerve fiber in human epidermis and dermis has been proven to be a useful method for demonstration of small fiber neuropathy. Quantification of intraepidermal nerve fiber density using anti-Protein Gene Product 9.5 (PGP 9.5) antibody is standardized method to diagnose the small fiber neuropathy. Skin biopsy method also makes it possible to differentiate the type of nerve fibers by using different antibodies. Quantification of dermal structures with different type of nerve fibers could be used to invest pathophysiologic mechanism of diseased state.

Langenbeck씨 수술법에 의한 구개총상치험례 (A CASE OF PALATAL GUNSHOT WOUND OPERATED BY LANGENBECK METHOD)

  • 유광희;심영섭;용호택
    • 대한치과의사협회지
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    • 제13권7호
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    • pp.629-632
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    • 1975
  • The clinical investigation and operation procedure were described on the gunshot wound which involved on soft, hard palate and nasal cavity. The patient, 19 years old, female, admitted in Han Yang Medical Center with clinical diagnosis of maxillofacial injuries on Nov. 1973. No Significant signs include of airway obstruction, Oro-nasal bleeding were revealed only exception of rupture and perforation on the soft, hard palate. For closure and reduction of destructed palatal wound, operation was done in out patient dental clinic under local anesthesia by means of Langenbeck method. And to control of post-operative inflammation and reactive swelling, administration of accurate antibiotics and physical therapy were performed for 5 days after operation. On the 10th day after administration, patient was discharged with satisfactory result of operation.

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