• Title/Summary/Keyword: Clinical effectiveness

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Effects of the Gagam-Bopyeyangyeongjeon on the Lung Weakness Children(肺系虛弱兒) (폐계허약아(肺系虛弱兒)에 대한 가감보폐양영전(加減保肺養營煎)의 임상적 효능 연구)

  • Gok, Su-Yeong;Jung, Sun-Kyung;Lyu, Sun-Ae;Lee, Seung-Yeon
    • The Journal of Pediatrics of Korean Medicine
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    • v.24 no.2
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    • pp.88-98
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    • 2010
  • Objectives The purpose of this study is to evaluate the clinical effectiveness and prophylactic treatment effectiveness of Gagam-Bopyeyangyeongjeon(GGBYJ) on the Lung Weakness Children(肺系虛弱兒) who catch cold easily. Methods The study has been carried out from 27 children, who were treated with GGBYJ in Department of Pediatrics, $\bigcirc\bigcirc$ Oriental Medical Hospital from August to December in 2009. The study was completed through patient chart review and telephone survey. Results 1. Immediately after the treatment, there was significantly decreasing(p=0.005) on respiratory symptoms in the Lung Weakness Children(肺系虛弱兒) who catch cold easily. 2. After the treatment, when season changes (three months later), there were preventive and continuous effects on reducing morbidity and on decreasing degree of symptoms against new respiratory infections compared to the previous year before taking medicine. 3. GGBYJ improved the respiratory symptoms, and also anorexia, constipation, heights, skin and fatigue. Conclusions In conclusion, there were significant clinical and preventive effectiveness of GGBYJ for the Lung Weakness Children(肺系虛弱兒) who caught a cold easily. Further studies are needed with more clinical cases.

Systematic Review for the Development of the Clinical Study with Economical Assessment Protocol on Facial palsy (얼굴마비의 임상연구병행 경제성평가 프로토콜 개발을 위한 체계적 문헌고찰연구)

  • Gong, Na-Gyeong;Seo, Eunsung;Seon, Ji-Hye;Kim, Nam-Kwen
    • The Journal of Korean Medicine
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    • v.38 no.1
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    • pp.46-55
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    • 2017
  • Objectives: The aim of this study is reviewing the literature to extract the key parameter, study design, perspective, cost-effectiveness index and find the calibration parameter for the clinical study with economical evaluation protocol on facial palsy. Methods: Literature search is performed using PUBMED for literature published from January 2000 to December 2016. We included randomized controlled trials(RCTs) and modelling study with economic assessment in which human participated. Results: As a result of literature search, the 198 articles were found. After reviewing the title, abstract and full text, the 5 articles were selected. Selected articles are classified into 4 RCT studies dealing with quality of life and 1 CEA(cost-effectiveness analysis) study. Conclusions: We found reliable key parameters, calibration parameters and elements of economical assessment study, which might be necessary factors for developing research protocol of clinical trial with economic evaluation about facial palsy patients.

Correlation between Perception and Clinical Achievements of Nursing Students (간호학생의 지각과 실습성적 간의 상관 연구)

  • 한상숙
    • Journal of Korean Academy of Nursing
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    • v.6 no.2
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    • pp.25-31
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    • 1976
  • The present study was carried out for the period from July 14 through September 13, 1975 by means of questionnaire distributed to 300 nursing students whose extent of satisfaction is known to be relatively low compared with other students of the different course of study by applying the perceptual orientation scale based on the principle defining that the effectiveness in maintaining helpful relation with others in human society depends upon the perception possessed by individuals, The present study was intended to investigate the effectiveness of nursing profession for nursing students of the 4- year system and 3- year system nursing school and relationship between perceptual orientation and clinical achievements, thereby, attempting more efficient application of the perceptual orientation scale. The results obtained are summarized as follows : 1. There was observed no significant difference in perceptual orientation between the nursing students of the 4- year system and 3- year system nursing schools. 2. There was observed significant correlation between the perceptual orientation and clinical achievements of the nursing students. 3. In the comparison of the perceptual orientation Point and mean value by school significant difference was observed between schools other than B and C schools of the 4 - year system. 4. Marked correlation was observed between the perceptual orientation and clinical achievements of the students of 4 - year system nursing courses. 5. Low correlation was observed between the perceptual orientation and clinical achievements of the students of the 3- year system nursing school.

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Rapid and Sensitive Detection of Hepatitis C Virus in Clinical Blood Samples Using Reverse Transcriptase Polymerase Spiral Reaction

  • Sun, Wenying;Du, Ying;Li, Xingku;Du, Bo
    • Journal of Microbiology and Biotechnology
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    • v.30 no.3
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    • pp.459-468
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    • 2020
  • This study established a new polymerase spiral reaction (PSR) that combines with reverse transcription reactions for HCV detection targeting 5'UTR gene. To avoid cross-contamination of aerosols, an isothermal amplification tube (IAT), as a separate containment control, was used to judge the result. After optimizing the RT-PSR reaction system, its effectiveness and specificity were tested against 15 different virus strains which included 8 that were HCV positive and 7 as non-HCV controls. The results showed that the RT-PSR assay effectively detected all 8 HCV strains, and no false positives were found among the 7 non-HCV strains. The detection limit of our RT-PSR assay is comparable to the real-time RT-PCR, but is more sensitive than the RT-LAMP. The established RT-PSR assay was further evaluated for detection of HCV in clinical blood samples, and the resulting 80.25% detection rate demonstrated better or similar effectiveness compared to the RT-LAMP (79.63%) and real-time RT-PCR (80.25%). Overall, the results showed that the RT-PSR assay offers high specificity and sensitivity for HCV detection with great potential for screening HCV in clinical blood samples.

Comparison of the effectiveness of essential oil mouthrinse and interdental brush in patients with fixed orthodontic appliances (Original Article 1 - 교정 장치를 접착한 환자에서 essential oil mouthrinse와 치간 칫솔의 효과 비교)

  • Hong, Sook-Chan;Kang, Sung-Taek;Shin, Joo-Hee;Lim, Yong-Kyu;Lee, Dong-Yul
    • The Journal of the Korean dental association
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    • v.48 no.5
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    • pp.371-378
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    • 2010
  • The objective of this study was to compare the effectiveness of essential oil mouthrinse and interdental brush for oral hygiene in orthodontic patient. 90 patients, with fixed orthodontic appliances, were divided into 3 groups(Group 1: patients who had only used toothbrush, group 2: toothbrush + essential oil mouthrinse, group 3: toothbrush + interdental brush). Then, plaque index(PI) and gingival index(GI) were evaluated at before(T0), 3 weeks after(Tl) and 6 weeks after(T2) the experiment. The present study revealed the following conclusions: (1) There was statistically significant decrease in PI and GI of groups 2 and 3 comparing to those of group 1 during 6 weeks.(p<0.05) (2) There was no significant difference in the level of decrease in PI and GI between group 2 and group 3.(p<0.05) The present study thus implied that use of mechanical or chemical aid such as interdental brush and mouth rinse in addition to toothbrushing may help maintaining oral hygiene in patients undergoing fixed orthodontic treatment for prolonged duration.

Clinical Test for Evaluation of Effectiveness of the Micro-current Stimulation in Facial Skin Care (미세전류 자극이 얼굴 피부개선에 미치는 영향에 관한 임상시험 연구)

  • Cho, Seungkwan;Kim, Seong Guk;Kim, Yong-Min;Park, Se-Keun;Lee, Chi Hwan;Kim, Hansung
    • Journal of Biomedical Engineering Research
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    • v.37 no.5
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    • pp.195-207
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    • 2016
  • This study examined the effectiveness of micro-current stimulation (MCS) to improve the facial skin qualities by performing clinical test. The MCS is generally known that provide healing response in the damaged tissue and pain relief through activating the adenosine triphosphate (ATP) and protein synthesis. In here, we can hypothesize that the improvement of facial skin qualities may occur due to MCS, since the induction of micro-current from outside may enhance the cellular activity according to ATP activation. From the clinical test, our results showed that a variety of evaluating categories, which is able to assess the skin qualities, significantly enhanced due to stimulation of micro-current after 7 and 14 days. Therefore, we can estimate that MCS in human facial skin may be effective to improve the skin qualities.

Effects of a Psychiatric Nursing Clinical Practice Program Using Situation-Oriented Case-Based Learning: A Qualitative Study

  • Lee, Sowon;Kim, Boyoung
    • International Journal of Advanced Culture Technology
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    • v.10 no.3
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    • pp.210-219
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    • 2022
  • Psychiatric nursing is a specialty where nursing students experience many difficulties in applying what they have learned in theory to clinical practice. Therefore, a situation-oriented case-based strategy is required to help them overcome the limitations of psychiatric nursing clinical practice and reduce their burden. This study aimed to measure the effectiveness of a psychiatric nursing clinical practice program using situation-oriented case-based learning. Participants comprised 63 nursing students in psychiatric nursing classes. The students were asked to create a scenario of interaction between a nurse and patient based on a case study. Empathy, therapeutic communication ability, and attitudes toward mental illnesses were measured. We analyzed the effectiveness of the program by comparing changes in the nursing students' empathy, therapeutic communication ability, and attitude toward mental illness after the program. The participants showed significant increases in empathy and therapeutic communication abilities. However, there were no significant changes in attitudes toward mental illnesses. Based on the results of this study, it is expected that situation-based learning will be effective for students who have difficulties in certain aspects, such as COVID-19, or where there are limited clinical practice opportunities, such as psychiatric nursing.

Systematic Review of Soyeom Pharmacopuncture Therapy for Pain (임상에서 흔히 접하는 통증에 대한 소염약침요법의 체계적 문헌고찰)

  • Kim, Myeong-Kyu;Seo, Ha-Ra;Ha, Hyun-Ju;O, Tae-Yeong;Jeon, Dong-Hwi;Li, Yu-Chen;Lee, Jae-eun;Lee, Eun-Jung;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.27 no.3
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    • pp.95-105
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    • 2017
  • Objectives To evaluate the evidence supporting the effectiveness of Soyeom pharmacopuncture therapy for Pain. Methods We conducted search across 6 electronic databases (Pubmed, CAJ, Oasis, RISS, DBPIA and KoreanTK) and 2 journals to find clinical trials that used Soyeom pharmacopuncture therapy as treatment for pain. The methodological quality of Randomized controlled clinical trials (RCTs) was assessed using the Cochrane Risk of Bias (RoB) tool, while NRCTs (Non-Randomized controlled clinical trials) were assessed using the Risk of Bias Assessment tool for Non-randomized Study (RoBANS) tool. Results Among 75 articles that were searched, 5 RCTs and 2 NRCTs were finally selected. Among 7 selected studies, all studies showed that Soyeom pharmacopuncture therapy has significant effect on Pain. Conclusions Our systematic review found encouraging but limited evidence of Soyeom pharmacopuncture therapy for Pain. We recommend clinical trials which compare the effectiveness of Soyeom pharmacopuncture therapy with other pharmacopuncture therapies to clarify the effectiveness of Soyeom pharmacopuncture therapy from other pharmacopuncture therapies.

Clinical Benefit of Computerized Cognitive Therapy in Patients with Brain Disease : A Systematic Review and Meta-Analysis (뇌질환 환자에서 전산화 인지치료의 임상적 유용성 : 체계적 고찰 및 메타분석)

  • Song, Seungil;Park, Sowon
    • Journal of The Korean Society of Integrative Medicine
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    • v.8 no.4
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    • pp.277-289
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    • 2020
  • Purpose : This study aims to confirm the clinical usefulness of computerized cognitive therapy program for patients with brain diseases in Korea and to present basic data that can confirm the effectiveness of computerized cognitive therapy program to experts related to rehabilitation in the future. Methods : A systematic review and meta-analysis research method was used to confirm the clinical effectiveness of computerized cognitive therapy applied to patients with brain diseases in Korea. Based on the national institute of health and medical colleges association (NECA) systematic literature manual and preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines for conducting research through systematic review and meta-analysis methods. Systematic review was PICOST-SD was used to research and select papers. For meta-analysis, the data was input and analyzed separately by literature result using the revman manager 5.3 program and the results were presented visually through tables and forest, funnel plot figure. Results : As a result of comprehensive analysis of the contents of the finally selected literature, it as found that studies on stroke and dementia were mainly conducted. In addition, through the evaluation of the quality of the literature, most of the existing computerized cognitive therapy studies were identified as high-quality studies, but the results were insufficient for randomization and blinding. And through meta-analysis, the clinical effectiveness of computerized cognitive therapy on cognitive function, activities of daily living, and visual perception function of patients with brain disease was found. Conclusion : The research literature that applied computerized cognitive therapy to brain disease subjects was comprehensively analyzed and identified. It is thought that this could be used as basic data on the characteristics of cognitive therapy that should be applied to patients with brain diseases in the future and the usefulness of computerized cognitive therapy program in actual clinical practice.

Chuna Manual Therapy for Primary Insomnia; A Review of Clinical Study (일차성 불면증의 추나 치료에 대한 문헌 연구 보고)

  • Hwang, Man-Suk
    • Journal of Korean Medicine Rehabilitation
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    • v.26 no.3
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    • pp.79-84
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    • 2016
  • Objectives To evaluate the evidence supporting the effectiveness of Chuna manual therapy for primary insomnia. Methods The researcher conducted search across the 3 electronic databases (Pubmed, CAJ and Oasis) to find all of randomized controlled clinical trials(RCTs) that used Chuna manual therapy as a treatment for primary insomnia. Results Four RCTs met inclusion criteria. The meta-analysis showed positive results for the use of Chuna manual therapy in terms of the PSQI when compared to medication treatments alone. Positive results were also obtained, in terms of the PSQI, when comparing Chuna manual therapy combined with acupuncture therapy to acupuncture therapy alone, but was not statistically significant. Conclusions The review found encouraging but limited evidence of Chuna manual therapy for primary insomnia. We recommend clinical trials which compare the effectiveness of Chuna manual therapy with usual care to obtain stronger evidence without the demerits of trial design.