• 제목/요약/키워드: Clinical effectiveness

검색결과 2,365건 처리시간 0.035초

만성요통환자에 대한 Bee Venom과 Sweet Bee Venom의 치료효능 비교 연구 (The comparison of Effectiveness between Bee Venom and Sweet Bee Venom Therapy on Chronic Lower Back Pain.)

  • 김재홍;장선희;윤현민;안창범;장경전;김철홍;송춘호;최하나
    • 대한약침학회지
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    • 제11권4호
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    • pp.15-24
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    • 2008
  • Objective The aim of this study is to investigate if Sweet Bee Venom(SBV) Therapy has the equal effect in comparison with Bee Venom (BV) Therapy on Chronic Lower Back Pain. Methods Clinical studies were conducted to 39 patients who were treated Chronic Lower Back Pain in Dept. of Acupuncture and Moxibustion, Dongeui University from March 1 to June 30, 2008. Subjects were randomly devided into 2 groups : BV treated group(Group A, n=19), SBV treated group(Group B, n=20) In BV treated group(Group A), we treated patients with dry needle acupuncture and BV Therapy. In SBV treated group(Group B), we treated patients with dry needle acupuncture and SBV Therapy. All process of treatment were performed by double blinding method. 1. To estimate the efficacy of venom in controlling pain, we have checked Visual Analog Scale(VAS). 2. For evaluating functional changes of patients, we have checked Oswestry Lower Back Disability Questionnaire(ODI). 3. To estimate Itching which is the most prominent symptom of allergic reaction, we have checked Visual Analog Scale(VAS). Results 1. In controlling pain, the results of BV treated group(Group A) is more effective than that of SBV treated group(Group B). 2. In promoting function, the results of BV treated group (Group A) is more effective than that of SBV treated group(Group B). 3. In controlling itching, the results of SBV treated group(Group B) is more effective than that of BV treated group(Group A). Conclusions According to the study, SBV Therapy shows more effective result than BV Therapy in controlling itching. But BV Therapy is more effective than SBV Therapy in controlling pain and promoting function.

만성(慢性) B형(型) 간염환자(肝炎患者) 삶의 질(質) (Quality of Life in Chronic Viral B Hepatitis Patients)

  • 김헌수;이민규
    • 정신신체의학
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    • 제6권1호
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    • pp.35-45
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    • 1998
  • Objectives : The purpose of this study was to determine correlation between coping strategies to disease and quality of life in chrome viral B hepatitis patients ; to investigate difference of coping strategies to disease and quality in life between chronic viral B hepatitis patients and normal persons ; and to identify major variables related to quality in life of chronic viral B hepatitis patients. Methods: The authors used Weisman coping strategy scale for measuring coping ability and efficacies, and the questionnaire for measuring quality of life including physical, psychological, social and economical aspects and satisfaction of sexual life was made by authors based on related literatures. Data were collected through questionnaire survey over a period from Sep 15, 1994 to Nov 11, 1994. Subjects served for this study consisted of 94 chronic viral B hepatitis patients visited to department of internal medicine at one general hospital and 100 normal persons visited to one general hospital for routine check up of health. The collected data were analyzed by SAS and the statistical methods for analysis were Chisquare, t-test and multiple regression analysis. Results : 1) It was revealed that coping strategies to disease significantly correlated to individual's quality of life. 2) There was no significant difference in coping strategies to disease between chronic viral B hepatitis patients and normal persons. However, chronic viral B hepatitis patients showed the lower scroes of quality of life in physical, psychological and economical aspects. 3) The most important variables which were influenced upon quality of life were coping strategies to disease and satisfaction of sexual life. That is, the more active coping strategies to diseases and the higher satisfaction of sexual life, consequently the higher quality of life was. Especially male patient group or normal persons showed each other the higher scores of quality of life in physical and psychological area than female group or patient group. 4) No statistically significant difference in coping strategies to disease and quality of life was found between HBeAg positive group and HBeAg negative group. Conclusions : The authors suggest that chronic viral B hepatitis patients may show the lower score of quality of life than normal person. Therefore, quality of life assessment should become an integral part of all clinical area that seek to assess the effectiveness of treatment. Also, through the interdisciplinary approach, a comprehensive paradigm that can better account for the effects of chronic disease on the individual' s quality of life should be developed.

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임상물리치료에 있어서 아로마테라피의 활용 (The Utilization of Aromatherapy in Clinical Physical Therapy)

  • 장정훈;정동혁;박래준
    • The Journal of Korean Physical Therapy
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    • 제15권1호
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    • pp.82-95
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    • 2003
  • Our health is intimately connected to the health of our environment. The contemporary world view which sees a radical distinction between humans as subjects and world as object can obscure our recognition of how much we rely on nature for health and survival. Indigenous traditions and contemporary scholars remind us that we live in a universe in which all things are connected, and in which nature continues to offer its gifts in co-creative partnership for the health and wellbeing of all. Living in awareness of our relationship with nature enables us to open more to the experience of nature's nurturing. Many complementary therapies derive from ancient practices that involve nature in healing partnership. Essential oils have been used for thousands of years. Hippocrates claimed that the way to health was through aromatic baths and massages. Much anecdotal evidence exists regarding aromatherapeutic positive effects on recipients. Aromatherapy is a branch of complementary or alternative therapy which is increasing in popularity, yet has scant scientific credibility. Aromatherapy should be defined as treatment using odors and practised as such. However, essential oils are usually used in conjunction with therapeutic massage and often combined with counselling of some kind. Aromatherapy complements and enhances the therapeutic powers of massage. Massage is one of the most wonderful ways to relax and is throughly beneficial to health. Massage can help unknot tense and aching muscles and other minor symptoms of stress, leaving patients fresh and energized. As the use of aromatherapy within a health care setting has grown so rapidly in recent years, and will continue to do so, the need for suitable training has become apparent. No health service can afford the risk of having staff who are inadequately trained in the practice of aromatherapy using essential oils incorrectly on those in a state of ill-health, especially if the essential oils used are not to a standard suitable for therapeutic use. Training to an acceptable level in aromatic therapy is essential for safety and effectiveness. Knowledge of the nature and make-up of essential oils, their effect on the body and the emotions, and how, when, and where to apply them is imperative in order for them to be beneficial to a patient's health. In order to achieve best practice, further research is necessary to explore the use of aromatherapy in the management of multiple disorder.

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불안장애의 정량화 뇌파 기반 뉴로피드백 훈련 효과 (The effects of QEEG based on neurofeedback training for anxiety disorder)

  • 조상희;조채형;박병운
    • 한국산학기술학회논문지
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    • 제17권9호
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    • pp.387-393
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    • 2016
  • 본 논문은 불안장애 환자 6명을 대상으로 32채널 정량화 뇌파(Quantitative Electroencephalograpy)와 뉴로피드백을 이용하여 뇌파를 분석하고 훈련하여 불안장애 환자의 정량화 뇌파 기반 뉴로피드백 훈련의 효과성에 대해 임상연구를 진행하였다. 불안수준을 측정하기 위해 심리생리학적 검사인 정량화 뇌파와 BAI(Beck Anxiety Inventory)를 실시하고, 그 결과를 통해 뉴로피드백 훈련도 진행하였다. 훈련 전 불안장애 환자의 정량화 뇌파 검사를 분석한 결과 6명 환자 모두의 측두엽에서 고베타파가 과잉활성화 된 양상을 볼 수 있었으며, 우뇌 측두엽(T4)의 세기(M=31.07)가 좌뇌 측두엽(T3)의 세기(M=29.11)보다 높았다. 이 결과를 바탕으로 뉴로피드백 프로토콜을 설정하고 훈련을 진행한 결과, 우뇌 측두엽의 베타파가 6명 환자 모두에게서 유의미하게 감소하였다. BAI점수를 분석한 결과 훈련 전의 평균이 23.57, 훈련 후의 평균이 12.14로 뉴로피드백 훈련 후 불안이 감소함을 알 수 있었다. 또한 약물복용을 했던 2명의 환자 중 한 명은 복용량이 줄어들었고 다른 한명은 약물을 중단하게 되었다. 이 결과는 정량화 뇌파 기반 뉴로피드백 훈련이 불안장애를 효과적으로 개선시키는데 사용될 수 있다는 것을 보여준다 하겠다.

일단계 전방 십자 인대 재 재건술 (One Stage Revision Anterior Cruciate Ligament Reconstruction)

  • 라호종;하정구;김상범;성정환;서정국;김진구
    • 대한관절경학회지
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    • 제13권2호
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    • pp.143-148
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    • 2009
  • 목적: 본 논문의 목적은 전방 십자 인대 재 재건술의 원인을 살펴보고, 일단계 재 재건술의 수술 술기의 유용성을 알아보고자 하는데 있다. 대상 및 방법: 2004년 11월부터 2008년 7월까지 전방 십자 인대 재 재건술을 시행한 33명을 대상으로 하였다. 전방 십자 인대 재 재건술의 원인은 대퇴터널의 종적 배열이 22예, 후외방 불안정성의 간과가 7예, 재건술 후 심한 외상이 3예, 재건술 후 심부 감염이 1예였다. 재 재건술시 대퇴 터널의 위치는 10시 또는 2시 방향의 외측 방향으로 하고, 경골터널은 대부분 기존의 터널을 이용하였다. 이전 수술 때 만들어진 이상 위치의 대퇴 터널은 고정 나사못 등을 제거하고, 수술 시 동종골을 나사 형태로 만들어 골이식을 시행하였다. 결과: 추시 기간은 평균 22.2개월(12~52개월)이었으며, 추시 결과 Lysholm score, IKDC 점수는 각각 재 재건술 전 평균 $61.5{\pm}16.8$, $63.9{\pm}15.1$에서 재수술 후 $86.3{\pm}11.5$, $81.3{\pm}14.3$으로 향상되었으며, KT-2000 arthrometer는 평균 $6.0{\pm}2.2\;mm$에서 $1.6{\pm}1.4\;mm$로 줄어들었다. 결론: 전방 십자 인대 일단계 재 재건술은 양호한 고정과 임상 결과로 유용한 술식으로 사료된다.

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2018 한국형 공황장애 치료지침서 : 초기 및 유지 약물치료 전략 (Korean Guidelines for the Treatment of Panic Disorder 2018 : Initial and Maintenance Treatment Strategies for the Pharmacological Treatment of Panic Disorder)

  • 김민경;이재헌;김민숙;김원;문은수;서호준;구본훈;양종철;이강수;이상혁;김찬형;유범희;서호석
    • 대한불안의학회지
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    • 제14권2호
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    • pp.53-62
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    • 2018
  • Objective : The Korean Association of Anxiety Disorders developed Korean guidelines for treatment of panic disorder (PD) 2018. In this paper, we discussed the consensus among psychiatrists, regarding initial and maintenance treatment strategies for pharmacological treatment of PD in Korea. Methods : Based on current treatment guidelines published by the American Psychiatric Association, the National Institute for Clinical Excellence, and the Canadian Psychiatric Association, we developed questionnaires pertinent to initial and maintenance treatment strategies for pharmacological treatment of PD. Seventy-two experts in PD answered questionnaires. We classified expert opinions into three categories, first, second, and third-line treatment strategies, by analyzing the 95% confidence interval. Results : Antidepressants, benzodiazepine anxiolytics, and cognitive-behavioral therapy (CBT) were recommended as treatments of choice (ToC), and first-line strategies for initial treatment of PD. Escitalopram, paroxetine, sertraline, and venlafaxine were preferred from among many anti-panic drugs. Mean starting dose of anti-panic drugs for initial treatment of PD was relatively lower, than that for other psychiatric illnesses such as major depressive disorder. In the case of maintenance treatment of PD, antidepressants and CBT were selected as ToC and first-line strategies. Patients were typically examined every four weeks during treatment, to review effectiveness and side effects of the drug. Pharmacotherapy was generally continued for one year or more. Conclusion : This study provides information about consensus among Korean experts regarding pharmacological treatment strategies for patients with panic disorder.

침치료에 익숙한 한국의 여자 임상시험 피험자를 대상으로 한 침관 변형을 통한 Minimal acupuncture 경험 (A study on the minimal acupuncture using a modified guide tube for Korean female participants familiar with acupuncture therapy)

  • 노진주;정수경;최민선;최선미;김동일
    • 대한한방부인과학회지
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    • 제20권3호
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    • pp.200-212
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    • 2007
  • Purpose: To find objective validity of minimal acupuncture using a modified guide tube as a method to verify the effect of acupuncture. Methods: Subjects of this study were participants of a randomized clinical trial which was practiced to verify the effect of acupuncture on postmenopausal hot flash. There were 2 arms of treatment, one's for active acupuncture group(AG) with manipulation and De qi, the other's for minimal acupuncture group(MG) using a modified guide tube which was designed to give minimal stimulation to the patient. After 8 weeks' treatment followed by 4 weeks' observation, participants were asked to fill in self-report forms on their education, previous experiences of acupuncture, original idea on the efficacy of acupuncture and recognition of blinding. Results: 19 participants of 26 in AG and 19 of 26 in MG completed the self-report form. There was no difference between AG and MG in their education(p=0.5976, Fisher exact test) and previous experiences of acupuncture(p=0.9999, Fisher exact test). In their original ideas on the efficacy of acupuncture, most of AG and MG respondents have been thought that acupuncture is very effective or quite effective, and there was no difference between 2 groups(p=0.5065). 16 of 19 in AG and 14 of 19 in MG believed that they underwent more effective way, there was no statistical difference between 2 groups(p=0.6928, Fisher exact test). Participants believed in undergoing more effective way not because they recognized treatment method, but they were satisfied with the effectiveness of treatment retrospectively. Conclusion: As the result of this study, these authors suggest that minimal acupuncture using a modified guide tube is acceptable as a method to verify the effect of acupuncture in acupuncture-familiar Korean culture. Also further studies on the stimulation-specific effect of minimal acupuncture are demanded.

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봉독의 젖소 유방염 유래 그람 양성 및 음성 세균별 항균효과 분석 (Antibacterial effect of bee venom against Gram-positive and negative bacteria isolated from mastitis in dairy cattle)

  • 정숙한;오상익;이한규;정영훈;허태영;한상미;백귀정;조아라
    • 한국동물위생학회지
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    • 제44권3호
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    • pp.169-174
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    • 2021
  • Mastitis is an inflammatory condition of the mammary gland, most often caused by bacterial infections, resulting in significant economic losses to the dairy industry. Antimicrobial resistance has been of great concern because of the extensive clinical use of antibiotics. For this reason, the development of new compounds as an alternative treatment to bovine mastitis is needed. Bee venom has been widely used as an oriental treatment for several inflammatory diseases and bacterial infections. The aim of the present study was to evaluate the antimicrobial activity of bee venom on bacteria isolated from bovine mastitis. A total of 107 isolates from bovine mastitic milk samples collected in 2019 and 2020 in Jeonbuk province. All bacterial isolates were tested for susceptibility to bee venom of the honey bee (Apis mellifera). In order to obtain comprehensive antibacterial activities of the bee venom, we measured the minimal inhibitory concentration (MIC) of the bee venom against bacterial strains. Bee venom showed significant inhibition of bacterial growth of Gram-negative bacteria Citrobacter spp., Escherchia coli, Klebsiella spp., Pseudomonas spp., Serratia spp. and Raoultella with MIC values of 96, 81, 72, 230, and 85 ㎍/mL, respectively, and Gram-positive bacterial Enterococcus spp., Staphylococcus spp. and Streptococcus spp. with MIC values of 29, 21 and 16 ㎍/mL, respectively. The results indicated that the MIC values were different depending on the bacterial strains, and those of Gram-positive bacteria were lower than those of Gram-negative bacteria for bee venom. These findings suggested that bee venom could be an effective antimicrobial treatment for bovine mastitis; however, further research is necessary to evaluate the mechanism underlying the antimicrobial action, its effectiveness/safety in vivo and effective application for therapeutic use.

Effectiveness after Designation of a Trauma Center: Experience with Operating a Trauma Team at a Private Hospital

  • Kim, Kyoung Hwan;Han, Sung Ho;Chon, Soon-Ho;Kim, Joongsuck;Kwon, Oh Sang;Lee, Min Koo;Lee, Hohyoung
    • Journal of Trauma and Injury
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    • 제32권1호
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    • pp.1-7
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    • 2019
  • Purpose: The present study aimed to evaluate the influence of how the trauma care system applied on the management of trauma patient within the region. Methods: We divided the patients in a pre-trauma system group and a post-trauma system group according to the time when we began to apply the trauma care system in the Halla Hospital after designation of a trauma center. We compared annual general characteristics, injury severity score, the average numbers of the major trauma patients, clinical outcomes of the emergency department, and mortality rates between the two groups. Results: No significant differences were found in the annual patients' average age ($54.1{\pm}20.0$ vs. $52.8{\pm}18.2$, p=0.201), transportation pathways (p=0.462), injury mechanism (p=0.486), injury severity score (22.93 vs. 23.96, p=0.877), emergency room (ER) stay in minutes (199.17 vs. 194.29, p=0.935), time to operation or procedure in minutes (154.07 vs. 142.1, p=0.767), time interval to intensive care unit (ICU) in minutes (219.54 vs. 237.13, p=0.662). The W score and Z score indicated better outcomes in post-trauma system group than in pre-trauma system group (W scores, 2.186 vs. 2.027; Z scores, 2.189 vs. 1.928). However, when analyzing survival rates for each department, in the neurosurgery department, in comparison with W score and Z score, both W score were positive and Z core was higher than +1.96. (pre-trauma group: 3.426, 2.335 vs. post-trauma group: 4.17, 1.967). In other than the neurosurgery department, W score was positive after selection, but Z score was less than +1.96, which is not a meaningful outcome of treatment (pre-trauma group: -0.358, -0.271 vs. post-trauma group: 1.071, 0.958). Conclusions: There were significant increases in patient numbers and improvement in survival rate after the introduction of the trauma system. However, there were no remarkable change in ER stay, time to ICU admission, time interval to emergent procedure or operation, and survival rates except neurosurgery. To achieve meaningful survival rates and the result of the rise of the trauma index, we will need to secure sufficient manpower, including specialists in various surgical area as well as rapid establishment of the trauma center.

가상현실 프로그램을 사용한 재활치료의 효과성 연구: 체계적 고찰 (A Study on the Effectiveness of Rehabilitation by Virtual Reality Program: Systematic Review)

  • 박다솔;신가인;우예신;박혜연
    • 재활복지
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    • 제22권3호
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    • pp.209-224
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    • 2018
  • 본 연구는 가상현실 프로그램을 사용한 재활치료의 효과성에 대해 체계적으로 분석하여 국내 임상현장에서 재활치료에 종사하는 의료인, 의료기사 및 연구자들에게 다양한 가상현실 기반의 재활치료와 효과성에 대한 정보를 제공하여 가상현실 기반의 재활치료가 임상에서 적절하게 적용될 수 있도록 하고자 한다. 연구 방법으로 학술연구정보서비스(Research Information Sharing Service; RISS), Google Scholar, Pubmed 데이터베이스를 사용하여 2007년 1월부터 2017년 12월까지의 논문을 검색하였다. 주요 검색어는 'Virtual Reality AND Rehabilitation', 'Virtual reality AND Effect'를 사용하였다. 최종적으로 10편의 해외 학술지에 게재된 논문을 본 연구의 분석 대상으로 선정하였다. 선정된 논문은 PICO (Patient, Intervention, Comparison, Outcome) 형식을 사용하여 정리하였다. 연구 결과 10개의 논문에서 참여한 대상자를 유형별로 분석한 결과, 대상자는 총 4가지로 분류되었으며 그 종류는 뇌졸중, 뇌종양, 파킨슨병, 신장질환이었다. 중재에 사용한 가상현실 기반 도구들은 IREX 3건(30%), X-box Kinect 2건(20%), Nintendo Wii 2건(20%), [Existing tool + VR]이 1건(10%), [Mobile application + VR]이 1건(10%)이었다. 중재 결과 10개의 논문 모두 기능향상이 나타났으며 신체기능이 24회(66%), 정신기능 6회(17%), 인지기능 5회(14%), 일상생활활동이 1회(3%)였다. 따라서 본 연구는 가상현실 기반 재활치료와 그 효과를 정리하여 재활치료서비스의 전문성과 질을 향상시키고, 영역을 확대하는 기초자료로 활용될 수 있을 것이다.