• Title/Summary/Keyword: Clinical Research Information Service

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A Survey on the Use of Electroacupuncture by Traditional Korean Medicine Doctor (한의사의 전침사용 임상실태 조사보고)

  • Moon, Jin-Seok;Lee, Sang-Hun;Kim, Jung-Eun;Kim, Bo-Young;Choi, Sun-Mi
    • Journal of Acupuncture Research
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    • v.28 no.6
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    • pp.53-68
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    • 2011
  • Objectives : This study was conducted to investigate status of electroacupuncture(EA) stimulation and adverse effects as a basic information of EA clinical treatment. Methods : The survey was carried twice by e-mail and online service against the traditional Korean medicine doctors registered in the Association of Korea Oriental Medicine. Results : Seventy-eight percent of 284 responders used the EA. The EA was the most widely used for the stimulation of the meridian-muscle on musculo-skeletal pain. In terms of methodological procedure, doctors mainly apply acupuncture with the needle of 2 or 3 pairs of 0.25mm diameter to the depth of 10-50mm for 15 minutes. Respondents used mainly at the frequency of 10Hz and the automatic setting at the intensity of around 3-4 grade. The adverse effects were investigated less then 3% in the 45.9% respondents and non in the 40.5%. The most priority content for better EA treatment was "development of the effective stimulation program". Conclusion : In the result of survey, the frequency of practical use of EA was very high but the applied disease was concentrated in the pain. Hereafter, if the clinical study for safety and effectiveness is secured and more convenient EA tool is developed, the clinical application of the EA is likely to be more expanded.

A Clinical Research Analysis of the Korean Medicine for Peroneal Nerve Palsy (비골신경마비에 대한 국내 한의치료 임상연구 동향 분석)

  • Hong, Su Min;Lee, Eun Jung
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.3
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    • pp.61-74
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    • 2019
  • Objectives This study aimed to review clinical studies about Korean medicine used in peroneal nerve palsy. Methods In 11 online databases (Earticle, Research Information Sharing Service, Oriental Medicine Advanced Searching Integrated System, KMbase, Korean Traditional Knowledge Portal, National Digital Science Library, MEDLINE/Pubmed, Ebscohost, Cochrane CENTRAL, EMBASE, China National Knowledge Infrastructure), we searched clinical studies about Korean medicine. Among the studies that we've searched, we excluded the studies that are not related to Korean medicine, case reports, randomized controlled trials and retrospective studies. As a result, 16 case studies and 1 randomized controlled trial are included. Results Total number of patients was 123. In these studies, acupuncture (100%), herbal medicine (58.8%), pharmacopuncture (58.8%), Korean physical therapy (58.8%), moxibustion (41.1%), cupping (41.1%) etc. were used. In acupuncture, GB34 and ST36 were most frequently used. Most of the herbal medicines used in these studies were different. Range of movement were most frequently used in outcome measure. Conclusions In this study, we reviewed studies about Korean medicine used in peroneal nerve palsy. It was difficult to clearly determine which intervention has improved the symptom. In the future, Further clinical studies will be needed to retain the evidence for the treatment of peroneal nerve palsy. And also more randomized controlled clinical trials to prove the efficacy of Korean medicine will be needed.

Predictors of massive transfusion protocols activation in patients with trauma in Korea: a systematic review

  • Dongmin Seo;Inhae Heo;Juhong Park;Junsik Kwon;Hye-min Sohn;Kyoungwon Jung
    • Journal of Trauma and Injury
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    • v.37 no.2
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    • pp.97-105
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    • 2024
  • Purpose: Massive transfusion protocols (MTPs) implementation improves clinical outcomes of the patient's resuscitation with hemorrhagic trauma. Various predictive scoring system have been used and studied worldwide to improve clinical decision. However, such research has not yet been studied in Korea. This systematic review aimed to assess the predictors of MTPs activation in patients with trauma in Korea. Methods: The PubMed, Embase, Cochrane Library, Research Information Sharing Service databases, KoreaMed, and KMbase were searched from November 2022. All studies conducted in Korea that utilized predictors of MTPs activation in adult patients with trauma were included. Results: Ten articles were eligible for analysis, and the predictors were assessed. Clinical assessments such as systolic and diastolic blood pressure, shock index (SI), prehospital modified SI, modified early warning system (MEWS) and reverse SI multiplied by the Glasgow Coma Scale (rSIG) were used. Laboratory values such as lactate level, fibrinogen degradation product/fibrinogen ratio, and rotational thromboelastometry (ROTEM) were used. Imaging examinations such as pelvic bleeding score were used as predictors of MTPs activation. Conclusions: Our systematic review identified predictors of MTPs activation in patients with trauma in Korea; predictions were performed using tools that requires clinical assessments, laboratory values or imaging examinations only. Among them, ROTEM, rSIG, MEWS, SI, and lactate level showed good effects for predictions of MTPs activation. The application of predictors for MTP's activation should be individualized based on hospital resource and skill set, also should be performed as a clinical decision supporting tools.

Clinical Effectiveness of Traditional Herbal Medicine in the Treatment of Central Post-Stroke Pain and Thalamic Syndrome: a Systemic Review and Meta-analysis of Randomized Clinical Trials Based on Traditional Chinese Medicine Journals (뇌졸중 후 중추성 통증 및 시상증후군에 대한 한약치료의 효과 : 체계적 고찰 및 메타분석 - 중의학 저널을 중심으로)

  • Jung, Yu-jin;Kang, Eun-jin;Hong, Sang-hoon
    • The Journal of Internal Korean Medicine
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    • v.40 no.3
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    • pp.295-311
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    • 2019
  • Objectives: This research aimed to investigate Chinese clinical studies on the treatment of central post-stroke pain (CPSP) and thalamic syndrome after stroke with traditional herbal medicine (THM). Methods: Randomized controlled trials verifying the effects of herbal medicine on treating CPSP and thalamic syndrome after stroke were included in the study. Electrical and hand search were conducted in the China National Knowledge Infrastructure (CNKI), National Discovery for Science Leaders (NDSL), Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (Oasis) for CPSP and thalamic syndrome after stroke. A literature search was performed in the Chinese and Korean databases for papers published from January 1, 2010 to October 1, 2018. The selected literature was assessed by Cochrane's risk of bias. Results: Twelve reports on randomized controlled trials met the inclusion criteria from the 227 identified reports. Effective rate, comparison of visual analogy scale, present pain intensity, pain grading index, recurrence rate, follow-up, and a 36-item short form survey instrument were used to evaluate the treatments. The effective rate of the treatment group was significantly higher than that of the control group in all papers. Side effects occurred less frequently in the treatment group than in the western medicine control group. Conclusions: The treatment of CPSP and thalamic syndrome after stroke with THM was shown to be highly effective. Additional well-designed clinical trials are needed. This study can be used as a basis for further research on the treatment of CPSP and thalamic syndrome after stroke.

A Research to Evaluate the Reliability and Validity of Pattern Identifications Tool for Cognitive Disorder: A Clinical Study Protocol (인지장애 변증평가도구의 신뢰도와 타당도 평가: 임상연구 프로토콜)

  • Lee, Ji-yoon;Kim, Hwan;Seo, Young Kyung;Kang, Hyung Won;Kang, Wee-Chang;Jung, In Chul
    • Journal of Oriental Neuropsychiatry
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    • v.29 no.4
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    • pp.255-266
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    • 2018
  • Objectives: The objective of this study was to evaluate the reliability and validity of Pattern Identifications Tool for Cognitive Disorders (PIT-C) and verify the correlation with other related scales. Methods: The study in this protocol is a single group, prospective, observational one. The subjects of the study were men and women between the ages of 45 and 85, diagnosed with neurocognitive disorders by Diagnostic and Statistical Manual of Mental Disorder (fifth Edition) criteria (n=60, Clinical Dementia Rating (CDR)=0.5, Korean Version of Montreal Cognitive Assessment $(MoCA-K){\leq}22$). The reliability of PIT-C was evaluated as test-retest and inter-rater reliability. And correlation between PIT-C and other related scales was also assessed. Results: This study was approved by the Institutional Review Board (IRB) of Dunsan Korean Medicine Hospital of Daejeon University and registered in the Clinical Research Information Service (CRIS), and was made public in advance to ensure transparency of the research process and conduct ethical clinical trials. Conclusions: The results of this study can be used to classify neurocognitive disorders as Korean medicine and PIT-C will be helpful tool for primary health care.

Review of Research Topics on Abdominal Examination (복진(腹診)에 대한 국내 연구동향 분석 및 연구방향 제안)

  • Kim, Jihye;Park, Jeong Hwan;Kim, Keun Ho
    • The Journal of Korean Medicine
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    • v.37 no.3
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    • pp.1-12
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    • 2016
  • Objectives: The abdominal examination is a diagnosis method for determining a morbid condition of the chest and abdomen by touching and pressing. This study reviewed research trends concerning the abdominal examination and suggested of future research directions for quantification of abdominal examination. Methods: A systematic literature search was carried out for relevant articles published between 2000 and 2016 in five databases such as Korean studies Information Service System(KISS), Oriental Medicine Advanced Searching Integrated System(OASIS), DataBase Periodical Information Academic (DBpia), National Digital Science Library and PubMed based on the Keywords 'abdominal examination'. Results: 128 articles were collected for analysis. Overview on the abdominal examination based on selected 17 articles. Then selected articles have been reclassified by diseases of clinical research and parameters for diagnosis of abdominal examination. Conclusions: Taken together, instrument for quantitative evaluation of abdomen characteristic fit to the traditional Korean Medicine have not yet developed. It is suggested that in order to dominate the market about abdominal examination in advance, more concern should be paid to establishing appropriate development of quantitative criteria and instrument. This review will help researcher to systematically understand and to develop Korean medical device as globally competitive device.

Assessment of the Application Status of Transcutaneous/Percutaneous Vagus Nerve Stimulation for Musculoskeletal Pain: A Scoping Review for Utilization in Korean Medicine and Subsequent Research (경피적 미주 신경 자극술의 근골격계 통증에 대한 적용 현황 파악: 한의학적 활용 및 후속 연구를 위한 Scoping Review)

  • Gun Hee Bae;Jeong Hoon Ahn;Dong Jin Jang;Jeong Hee Noh;Jae Kwon Shin;Eun Seok Jin;Sun Kyu Yeom;Seung Ju Oh
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.1
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    • pp.65-81
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    • 2024
  • Objectives This study aimed to understand the general research trends, applicated disease, and methodology of transcutaneous/percutaneous vagus nerve stimulation, contemplating its clinical use in traditional Korean medicine and future research directions. Methods A scoping review was conducted following Arksey and O'Malley Framework Stage and adhering to the PRISMA extension for scoping reviews: checklist and explanation. Papers published until October 30, 2023, were investigated across 10 databases (PubMed, Embase, Scopus, Web of Science, China National Knowledge Infrastructure, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, KMbase, Science ON, Research Information Sharing Service. The search terms used were 'Transcutaneous/Percutaneous vagus nerve stimulation'. Results Since 2021, the application of transcutaneous/percutaneous vagus nerve stimulation for musculoskeletal symptoms has been actively researched, predominantly in Asia (37%), Europe (37%), and North America (21%). All 19 papers were part of clinical studies. Chronic pain was noted that most applied disease, it also was found to potentially aid in acute post-surgical pain relief. Major assessment tools include not only simple pain metrics but also pain perception, vagal nerve tension, quality of life, and inflammatory markers. Most procedures were carried out through the ear, which offers a favorable site for therapeutic stimulation without notable side effects. And parameter analysis, frequencies typically ranged around 25 Hz to 30 Hz, while pulse widths were commonly set at 250 ㎲ or 300 ㎲. Conclusions Transcutaneous/percutaneous vagus nerve stimulation is easily accessible through acupuncture in Korean medicine. Therefore, if future studies establish parameters and clinical significance, it could be utilized as a therapeutic modality.

Clinical Effect of Injinho-tang on Hyperbilirubinemia in Hepatobiliary Disorders: A Systematic Review (간담도 질환에서의 고빌리루빈혈증에 대한 인진호탕의 임상 효과 : 체계적 고찰)

  • Keunjoon Park;Heekyung Kang;Changwoo Han
    • The Journal of Internal Korean Medicine
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    • v.43 no.6
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    • pp.1149-1161
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    • 2022
  • Purpose: This systematic review was conducted to evaluate the clinical effects of Injinho-tang on hyperbilirubinemia in hepatobiliary disorders. Methods: We searched for randomized controlled clinical trials that had administered Injinho-tang as an intervention in the following medical databases: Public/Publisher MEDLINE (PubMed), Excerpta Medica dataBASE (EMBASE), Cochrane library, Research Information Sharing Service (RISS), ScienceON, Oriental Medicine Advanced Searching Integrated System (OASIS), and China National Knowledge Infrastructure (CNKI). Among the retrieved studies, only trials that met the inclusion criteria were selected, and serum total bilirubin values were extracted and analyzed from the finally selected trials. Results: The serum total bilirubin values of 1,302 patients with various hepatobiliary diseases were synthesized through a meta-analysis, which confirmed a decrease in serum total bilirubin of 21.03 𝜇mol/L (95% CI -29.58~-12.49, p<0.01) in the group administered with Injinho-tang compared with the control group. Conclusions: Injinho-tang is effective in alleviating hyperbilirubinemia in hepatobiliary diseases when administered with conventional treatment. However, the potential risk of bias, high heterogeneity among the included trials, and differences in herbal composition are limitations of the results of this meta-analysis.

Literature Review of Domestic Randomized Controlled Trials for Hominis Placenta Pharmacopuncture

  • Hea Sun Chun
    • Journal of Acupuncture Research
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    • v.41
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    • pp.228-244
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    • 2024
  • This study was conducted to analyze research trends, quality, and bias of pharmacopuncture studies, etc., on domestic randomized controlled trials (RCTs) using hominis placenta pharmacopuncture (HPP). A total of 13 domestic RCTs were selected by searching two domestic online databases (Research Information Sharing Service and Oriental Medicine Advanced Searching Integrated System). The publication of domestic RCTs using HPP began in 2000, and most studies targeted peripheral facial paralysis and gynecological diseases. Most studies have shown the Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) checklist reporting rate of > 50.0%; however, four subitems, including "depth of insertion," showed a reporting rate < 50.0%. Some studies have shown significant improvement in the HPP group; however, the sample size was diverse, the observation period was short, the effect of stimulation of the same acupoint between the two groups could not be ruled out, and the overall risk of bias was mostly "some concern." In addition, further development of STRICTA that reflects the characteristics of pharmacopuncture therapy is necessary.

Satisfaction in the National Cancer Screening Program for Breast Cancer with and without Clinical Breast Examination

  • Han, Mi-Ah;Jun, Jae-Kwan;Choi, Kui-Son;Park, Eun-Cheol;Lee, Hoo-Yeon
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.63-67
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    • 2012
  • The purpose of this study was to evaluate whether screening by clinical breast examination (CBE) in addition to mammography affected participant satisfaction in the National Cancer Screening Program (NCSP). Data were derived from the Quality Evaluation of National Cancer Screening satisfaction survey. This population-based nationwide telephone survey included participants who had been screened by the NCSP for breast cancer between June and August 2010 (n=2,370), and collected information on satisfaction with screening and screening service use. Five multiple regression models were used to determine satisfaction according to screening method, and according to each of five satisfaction measures (pre-screening information transfer, staff interpersonal skills, physical surroundings, reporting of results and general satisfaction). A total of 1,858 (78.4%) participants were screened by mammography alone and 512 (21.6%) by both mammography and CBE. Satisfaction was significantly higher in subjects screened by both mammography and CBE compared with those screened by mammography alone.