• 한국유체기계학회 논문집
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• 제7권6호
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• pp.38-44
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• 2004

In this study, the overall performance and the effect of the tip leakage flow of the centrifugal compressor with a refrigerant HFC-l34a were numerically studied using CFX-TASCflow. To study the effect of the tip leakage flow, the numerical study of the overall performance of HFC-l34a centrifugal compressor with a cascade diffuser was preceded and compared with the experimental result. Six different tip clearances were used to consider the influence of the tip clearance on the performance. The tip leakage flow was illustrated for qualitative discussion. The results obtained in this study can be applied to the determination of the cold clearance.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2004년도 유체기계 연구개발 발표회 논문집
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• pp.43-48
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• 2004

A screw-type centrifugal pump was manufactured to carry solids primarily and its impeller has a wide flow passage. However, the effect of flow passage shape on delay of the choke due to entrained air has not been clarified yet. Moreover, because its impeller has a particular shape, only few studies have tried to clarify the pump performance and details of internal flow pattern of that pump. For that reason, we carried out the pump performance experiment under air-water two-phase flow condition with different impeller tip clearances, pump rotational speeds and void fractions by using a small screw-type centrifugal pump designed to acquire basic data. In a general centrifugal pump, it was reported that loss of pump head from single-phase flow to the choke due to air entrainment new the best efficiency point was large. However, the loss near the best efficient point in a screw-type centrifugal pump became less than that in a general centrifugal pump.

• 약학회지
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• 제45권6호
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• pp.664-669
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• 2001

Acebutolol is almost absorbed after oral administration, but its bioavailability is reduced because of considerable first-pass metabolism through the gastrointestinal tract and liver. The purpose of this study was to report the pharmacokinetic changes of acebutolol (15 mg/kg,oral) and its main metabolite, diacetolol in rabbits pretreated (15 mg/kg, oral) and coadministered (15 mg/kg, S. C., bid for 3 days) with diltiazem. The plasma concentration and area under the plasma concentration-time curves (AUC) of acebutolol and diacetolol were significantly increased in rabbits pretreated and coadministered with diltazem. The elimination rate constant ( $K_{el}$ ) and total body clearances (CL $_{t}$) of acebutolol and diacetolol were significantly decreased and half-life of those were significantly prolonged in the rabbit. Metabolite percentage rate of diacetolol to the plasma concentration of total acebutolol in rabbits pretreated and coadministered with diltiazem were significantly decreased. The results suggest that the dosage of acebutolol should be adjusted when the drug would be administered chronically with diltiazem in a clinical situation.n.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 1994년도 추계학술대회 논문집
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• pp.80-94
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• 1994

As for axisymmetirc sheet metal forming, a kind of pick-up apparatus for body-wrinkling is deviced. Experiments with both hemispherical and flat headed punches, with various clearances between punch and die, with respect to three kinds of materials each of which has two thicknesses, are performed. Firstly the process of evolution of body-wrinkling is observed. Then the critical blank-holding force (or meridional tensile force) for suppression of body-wrinkling at a specified punch-stroke is measured for all cases mentioned above. An empirical formula for it is proposed. Deformation patterns and stress distributions are analysed by the use of FEM. A simplified critical condition for body-wrinkling is formulated and introduced into the FEM program. And its effectiveness is checked by comparison with the experimental results. Using this FEM system, the governing factors of body-wrinkling are cleared up.

• 소성∙가공
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• 제3권4호
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• pp.440-453
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• 1994

The multi-stage deep-drawing processes including normal-drawing, reverse-drawing, and re-drawing are analyzed by use of the rigid-plastic finite element method. Computational results on the punch/die loads and thickness distributions were compared with the experiments of the current drawing processes. Deep-drawing processes of the redesigned shell to improve the specific strength and stiffness were simulated with the numerical method developed. With varying several process parameters such as blank size, corner radii of tools, and clearances, the simulation results showed the improvements in reducing the forming loads. Also forming defects were found during simulation and appropriate blank size could be verified.

• 대한약리학회지
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• 제5권1호
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• pp.57-64
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• 1969

Acetylsalicylic acid, administered intravenously in a dose of 120 mg+250 mg/h, markedly decreased the urinary excretion of sodium and chloride, and slightly depressed potassium excretion, so that the ratio of urinary concentrations of potassium to sodium increased after ASA. Osmolar and free water clearances also diminished during water diuresis, and free water reabsorption $(T^cH_2O)$ decreased after ASA during mannitol diuresis. Glomerular filtration rate and urine flow rate changed little. When infused directly into a renal artery, ASA exhibited identical action on both kidneys, indicating that the renotropic action is mediated by some endogenous humoral agents or by some metabolites of ASA. A dose of 100 mg i.v. of spironolactone, a aldosterone antagonist, slightly reversed the renal reflect when given during maximum action of ASA. Ethacrynic acid could display its full diuretic action unhindered during maximum ASA action. Above observations lead to the suggestion that acetylsalicylic acid might release aldosterone and the action on electrolyte excretion may be mediated by the mineralocorticoid.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 춘계학술대회논문집
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• pp.1091-1098
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• 2003

Flexure bearings have been used in linear-resonant compressors to maintain a non-contacting clearance seal between the piston and cylinder. There are two types of tangential cantilever bearing and spiral arm bearing with flexure bearings. A newly devised linear flexure bearing (KIMM-Ml) for compression refrigeration machines is disclosed having improved tight gas clearance maintaining capability for better system performance. KIMM-Ml is an integrated device comprising an axially moving diaphragm with circumferentially arranged arc-shaped flexure blades secured between rim and hub spacers, which turn out to have higher radial stiffness than the one with circumferential tangential cantilever flexure blades. It is expected for KIMM-Ml to play a key role in designing long life, special purpose compression refrigeration machines by providing frictionless, non-wearing, linear movement and radial support for the machines as well as a gas clearance seal by maintaining extremely tight clearances between piston and cylinder.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집B
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• pp.121-126
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• 2001

In this study, the 4-way spool valve characteristics are clearly defined and proposed new type of spool valve. This paper presents governing equations of the flow through clearances between sleeve and spool as a model of orifice flow for null characteristic analysis, and programmed analysis software of it. This software is possible to basically analysis that not only which case of open center, closed center or critical center but +,- displacement of spool, lab position, boundary region and spool opening of the valve, and to estimate the pressure variation in the spool and external leak flow variation. We are convinced that the scale of load pressure difference is changed as lab condition of spool valve, and this scale is changed with boundary point on the annular clearance. It is vary useful to designer and user of spool valve with this design data and analysis software.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 1999년도 춘계학술대회 논문집
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• pp.105-110
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• 1999

Wire electrical discharge machining (WEDM) is one of the unconventional machining processes, which is utilizing electrical energy to remove work-piece. In recent years WEDM used widely in die-sinking industry because WEDM can machine any hard materials if only it has conductivity and can machine accurately to the complex geometry, for fine wire is used in WEDM for the tool electrode. However WEDM is non-contact machining process, which is utilizing discharge phenomena occurring between two electrodes, the size of the machined part is larger than that of the tool electrode size. It is called discharge gap or clearance the difference size between the tool electrode and the machined part in WEDM. By the experiment clearances according to the machining condition was investigated.

• 약학회지
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• 제25권1호
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• pp.15-25
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• 1981

This study was attempted to investigate the action of debrisoquine, a sympathetic blocking agent presently employed in treating hypertension, on renal function and to elucidate the mechanism of its action. Debrisoquine, given intravenously, elicited increased urine flow, osmolar and free water clearances, along with marked increases in excretion of both sodium and potassium. Glomerular filtration rate also increased, but renal plasma flow tended to decrease, so that the filtration fraction tended to increase. Rates of reabsorption of sodium and potassium in renal tubules were also significantly diminished. The diuresis induced by debrisoquine was completely blocked by treatment with phentolamine and reserpine, and also markedly inhibited by acute renal denervation. Debrisoquine, when injected directly into a renal artery, produced antidiuretic effect and a reduction in urinary excretion of sodium and potassium, along with diminished renal plasma flow and increased filtration fraction. The above observations indicate that debrisoquine, when given intravenously, induces diuresis in the dog as a result of both diminished tubular reabsorption of electrolytes and of renal hemodynamic changes, which seem to be related to its inhibitory action of catecholamine-release from the sympathetic nerve endings.