• Korean Journal of Applied Biomechanics
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• v.21 no.5
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• pp.529-540
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• 2011

The purpose of this study was to evaluate the kinematic characteristics of $5^{th}$ and $6^{th}$ hurdle clearances during the final of the 110-m hurdles at the IAAF World Championships, Daegu 2011. To this end, the hurdling motions of the top 4 ranked male hurdlers in the competition were analyzed. A total of 12 cameras were used to record their motions, with a sampling frequency of 120 Hz. The cameras were calibrated using $11{\times}2{\times}1\;m$ control objects that covered all of the lanes (1st~8th lanes). After analyzing all the data, we arrived at the following results. In the take-off phase, all athletes revealed similar take-off times (CT), and similar distances from the take-off to hurdleto (L1) and hurdle to landing (L2). In particular, Turner, ranked $3^{rd}$, had an inconsistent L2 and may need further training to correct it. In the flight phase, Richardson, ranked $1^{st}$, showed the longest flight distance, whereas Xiang, who was ranked $2^{nd}$, showed the highest CG height from the hurdle. For the step patterns, to increase the pitch frequency, Richardson and Xiang used shorter 3-step lengths than Turner and Oliver.

• The Korean Journal of Pharmacology
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• v.5 no.2
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• pp.141-148
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• 1969

The direct effect of isoproterenol on renal function, when given intravenously, is usually obscured by its potent hypotensive action. To obviate the latter action, isoproterenol was infused directly into one renal artery of the dog, the other kidney serving as a control for the general action. And following results were obtained. In the first series of experiments, the directic action of isoproterenol was ascertained. $1.0\;{\mu}g/kg/min$. reduced on both kidneys the urine flow, clearances of PAH and creatinine, as well as the amount of sodium excreted, but the effect was weaker on the experimental side than on contralateral side. With $0.1\;{\mu}g/kg/min$., two cases among 6 experiments showed marked diuresis, two cases no apparent effect, and another two marked antidiuresis on the experimental kidney, whereas the contralateral kidney exhibited antidiuresis in all cases. Further reducing the dose unmasked the diuretic action on the ,experimental kidney. In another series, the effects of isoproterenol on the blood flow distribution within the kidney and on sodium concentration gradient within the kidney tissue were observed. $0.05\;{\mu}g/kg/min$ isoproterenol markedly increased the medullary plasma flow and slightly increased total renal plasma flow and glomerular filtration rate, along with concomitant increase in the amount of sodium excreted and osmolar clearance, and decrease in reabsorption of free water. Sodium concentration gradient markedly decreased in the experimental kidney, reaching 2/3 of the value observed in the contralateral kidney at the papilla. It is thus concluded that isoproterenol exerts a diuretic action, when infused directly into a renal artery, and the mechanism of the action rests on its hemodynamic action, substantiated as the increase in glomerular filtration and in the medullary blood flow, resulting in washout of hyperosmolality produced by the coutercurrent multiplier system.

• Journal of Energy Engineering
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• v.21 no.2
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• pp.187-193
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• 2012

In this study, it was experimentally investigated the effect of the clearances distance between the rod and the impinging plate on characteristics of the thermal flow. For the heat transfer enhancement of wall jet region, the right triangle and the square rods were arranged in front of the impinging plate with various clearance distances. As results, the heat transfer enhancement rate of potential core region at H/B=2 was higher than that of transition region at H/B=10. In this experiment range, the maximum heat transfer enhancement rate was about 46 % higher at the square rod with H/B=2 and C=1mm compared with the flat plate. The heat transfer enhancement rate of the right triangle rod was on average about 3 to 8 % higher than that of the square rod, regardless of the clearance.

• International Journal of Highway Engineering
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• v.19 no.6
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• pp.105-115
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• 2017

PURPOSES : The occurrence of unexpected disasters, including fire events, increases as the road network becomes complicated and traffic volume increases. When a fire event occurs on and under bridges, the damage extensively influences direct damage to structures, vehicles, and human life and secondary socioeconomic issues owing to traffic blockage. This study investigated potential fire-hazard risks on bridges of the Korean national route road. METHODS : The investigation was conducted using field investigation and analysis with satellite pictures and road views from commercial websites and the Bridge Management System (BMS). From the filed investigation, various potential fire resources were identified. The satellite pictures and road views were helpful in measuring and recognizing conditions underneath bridges, stowage areas, etc. RESULTS : There are various potential fire resources underneath bridges such as piled agricultural products, parked petroleum tanks, construction equipment, and attached high-voltage cables. A total of 94.6% of bridges have underneath clearances of less than 15 m. A bridge underneath volume that can stow a potential fire hazard resource was $7,332m^3$ on average, and most bridges have about $4,000m^3$ of space. Based on the BMS data, the amounts of PSC and steel girders were 29% and 25%, respectively. CONCLUSIONS : It was found that the amount of stowed potential fire hazard resources was proportional to the underneath space of bridges. Most bridges have less than 15 m of vertical clearance that can be considered as a critical value for a bridge fire. The fire risk investigation results should be helpful for developing bridge fire-protection tools.

• Journal of Pharmaceutical Investigation
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• v.25 no.3
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• pp.193-204
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• 1995

In order to examine the effect of extrahepatic cholestasis induced by common bile duct ligation on the hepatic function, the pharmacokinetics of antipyrine and d-propranolol were investigated in rats. In addition, in an attempt to observe the degree of direct hepatic injury, light and electron microscopic observations and conventional pathologic test using serum were performed. Five days after common bile duct ligation, antipyrine(15 mg/kg) and d-propranolol(3 mg/kg) were intravenously administrated to the rats, respectively. The total clearances of antipyrine and d-propranolol were significantly(p<0.05) decreased. Because hepatic clearance of antipyrine poorly extracted by the liver and that of d-propranolol highly extracted by the liver are respectively dependent on the hepatic intrinsic clearance and the hepatic blood flow, it may be concluded that extrahepatic cholestasis following five days after common bile duct ligation decreased the hepatic intrinsic clearance and the hepatic blood flow. SGPT, SGOT, cholesterol, bilirubin(total bilirubin, direct bilirubin) and alkaline phosphatase were significantly increased(p<0.05). The proliferation of bile ducts was prominent, and degeneration and necrosis of hepatocytes were observed by light microscope. Also, ultrastructurally, bile canaliculi were containing the amorphous materials and losing microvilli, and SER and RER in hepatocytes were dilated and vacuolated.

• Archives of Pharmacal Research
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• v.17 no.2
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• pp.124-130
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• 1994

Plasma phamacokinetics and renal excretion of theophylline (TP) and its metabolities were ivnestigated in rats. Plasma concentrations of TP declined in a monoexponential manner, while those of 1-methyluric (MU) and 1,3-dimethyluric(DMU) declined in a biexponential manner upon respective iv bolus injection of each compound at 6mg/kg dose. The total body clearances $(CL_r)$ of the metabolites were 4-6 fold larger than that of TP, while the distribution volumes of them at steady-state $(Vd_{ss})$ were 40-50% smaller than that of TP. The metabolites showed their plasma peaks in 30 min after iv injection of TP indicating than that to MU. Renal excretion of TP and its metabolites was studied in urine flow rate (UFR)-controlled rats. The renal clearance $(CL_r)$ of TP was inversely related to pasma TP concentrations, and much smaller than the glomerular filtration rate (GFR) suggesting tubular secretion and profound reabsorption in the renal tubule. The $(CL_r)$ of each metabolite also showed that inverse relationship, but far exceeded GFR suggesting that tubular secretion than GFR by ip injection of probenecid (142.7 mg/kg). It supports that the metabolies are secreted in the renal tubule, and suggests that they share a common transport system in their sectrtion processes with probenecid. On the other hand, the $(CL_r)$ of TP was not affected significantly by the probenecid treatment. Considering the inverse relationship of TP between the $(CL_r)$ and its ploasma concentrations,no effect of probenecid on $(CL_r)$ of TP is most likely due to negligible contribution of the secretion to the overall $(CL_r)$ of TP.

• Solar Energy
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• v.15 no.3
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• pp.127-140
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• 1995

This experimental study was carried out to examine the heat transfer characteristics of a 2-dimensional impinging air jet on a flat plate with a set of square rods. The objectives of the study were to investigate the flow and heat transfer characteristics caused by the square rods. Experiment was carried out first without using the rods to establish the baseline heat transfer performance. Then, rods of different widths and clearances were installed to cause the turbulence on the fluid flow. When rods are installed in front of the plate, the acceleration of the flow and the turbulence generation due to the rods and reattachment of the flow seem to contribute to the observed heat transfer augmentation and the heat transfer augmentation increases as the clearance decreases. With wider individual rod the heat transfer coefficient is higher, which is due to the increased acceleration and development of the eddies just before the rods.

• The Korean Journal of Pharmacology
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• v.16 no.1 s.26
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• pp.51-56
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• 1980

Phytolaccae Radix (PR), Brunella Herba (BH), Akebiae Lignum (AL) and Atractylis Rhizoma (AR) are some of the diuretic agents used in Chinese medicine and folk remedy. Water or methanol extracts of them (100mg/kg) were intravenously injected to rabbits in order to re-evaluate the effects on renal function. PR water extract elicited moderate diuresis while water extracts of BH, AL and methanol extract of AR had antidiuretic effects. Influence of PR on renal hemodynamics and $Na^+-K^+$-ATPase activity in rabbit kidney were observed in vivo and in vitro. The results were as follows: 1) Clearances of inulin and p-aminohippuric acid increased significantly after 15 minutes following the administration of PR water extract, but Na+ reabsorption rate was not changed. 2) The increase of $Na^+-K^+$-ATPase activity in renal cortex, outer and inner medulla was observed at 15 minutes after PR water fraction was given intravenously, and the change was most prominent in cortical area. 3) More than 50% of decrease in $Na^+-K^+$-ATPase activity in renal tissues was observed with PR water fraction $(10^{-2}g/ml)$ in vitro experiments. However, the inhibition of $Na^+-K^+$-ATPase activity was reversed with lower concentrations $(10^{-4}g/ml,\;10^{-6}g/ml)$ of PR water fraction in outer and inner medullary zone. These results suggest the diuretic effect of PR is due to improved renal hemodynamics, and contradictory reults concerning $Na^+-K^+$-ATPase activity require further investigation.

• Journal of Aerospace System Engineering
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• v.11 no.1
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• pp.28-34
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• 2017

Elastomeric o-ring performance and structure when subjected to a foreign object is studied using finite element analysis (FEA). Elastomeric o-rings have been studied using 2D analysis for a long time. Contact pressure is an important factor in o-ring design. When contact pressure is lower than applied pressure, leaking, vibration, and noise can occur; resulting in decreased output. In this study, we compared 2D and 3D analyses of elastomeric o-rings. Similar results were shown for 2D and 3D contact pressure. However, when an o-ring encounters foreign object matter, 3D analysis is required because contact pressure in every direction needs to be considered. We determined the influence of foreign matter on o-ring performance and structure by analyzing 10 cases with different clearances in a 3D model. Therefore, an o-ring encountering foreign object matter must be analyzed in 3D with the result included in the o-ring design.

• Journal of the Society of Naval Architects of Korea
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• v.39 no.3
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• pp.28-40
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• 2002

Turbulent flows around two-dimensional wing sections in ground effect are analysed by incompressible RANS equations and a finite difference method. The Baldwin-Lomax algebraic turbulence model is used to simulate high Reynolds number flows. The main purpose of this study is to clarify the two-dimensional ground effect and its flow characteristics due to different ground boundary conditions, i.e., moving and fixed bottom boundary. As a first step, to validate the present numerical code, the computational result of Clark-Y(t/C 11.7%) is compared with published numerical results and experimental data. Then, NACA4412 section in ground effect is calculated for various ground clearances with two bottom boundary conditions. According to the computational results, the difference in the lift and moment simulated with the two bottom boundary conditions is negligible, but the drag force simulated by the fixed bottom is to some extent smaller than that by the moving bottom. Therefore, it can be concluded that the drag force measured in a wind tunnel with the fixed bottom could be smaller than that with the moving bottom.