• The Journal of Korean Academic Society of Nursing Education
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• v.6 no.1
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• pp.132-146
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• 2000

The purpose of this study was to explain the relationship between empowerment and satisfaction of clinical practice in nursing students. The instrument of this study was a structured questionnaire included empowerment and satisfaction of clinical practice. The data was collected from september 28, 1999 to March 31, 2000 and analyzed by Cronbach alpha, descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient and simple regression by using SPSS Win program. The result of research were as follows: 1. There was significant difference according to the general characteristic factor. The total empowerment was predicted by meaning of nursing, university and college, relationship of peer, clearance of study purpose. Satisfaction of clinical practice was predicted by university and college, clearance of study purpose. 2. There was a significant correlation between empowerment and satisfaction of clinical practice(r=0.442, p=0.000). 3. Empowerment was the highest factor predicting satisfaction of clinical practice. A total of 19.5% of the variance was explained in the total satisfaction of clinical practice. It was found that the higher the degree of perceived empowerment, the higher the degree of satisfaction of clinical practice. Therefore, nursing faculty should plan interventions to inspire satisfaction level of clinical practice by empowerment.

• Nuclear Engineering and Technology
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• v.44 no.7
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• pp.709-718
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• 2012

The pressurized water reactor APR1400 adopts DVI (Direct Vessel Injection) for the emergency cooling water in the upper downcomer annulus. The International Standard Problem number 50 (ISP-50) was launched with the aim to investigate thermal hydraulic phenomena during a 50% DVI line break scenario with best estimate codes making use of the experimental data available from the ATLAS facility located at KAERI. The present work describes the calculation results obtained for the ISP-50 using the RELAP5/MOD3.3 system code. The work aims at validation and assessment of the code to reproduce the observed phenomena and investigate about its limitations to predict complicated mixing phenomena between the subcooled emergency cooling water and the two-phase flow in the downcomer. The obtained results show that the overall trends of the main test variables are well reproduced by the calculations. In particular, the pressure in the primary system show excellent agreement with the experiment. The loop seal clearance phenomenon was observed in the calculation and it was found to have an important influence on the transient progression. Moreover, the collapsed water levels in the core are accurately reproduced in the simulations. However, the drop in the downcomer level before the activation of the DVI from safety injection tanks was underestimated due to multi-dimensional phenomena in the downcomer that are not properly captured by one-dimensional simulations.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.05a
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• pp.214-219
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• 2002

As the tangential flow inside the clearance of tribe elements such as bearings and seals is increased as the shaft speed increases, the system stability will be decreased due to the increment of the instability parameter. To reduce the tangential flow inside the clearance of the balance sleeve, anti-swirl injection mechanism is applied. The balance sleeve is used in resisting the axial force induced by impeller in high pressure multi-stage pump. In this paper, total three cases are experimentally investigated; original balance steeve, anti-swirl injection balance steeve with 0 axial degree and anti-swirl injection balance sleeve with 30 axial degree. Experiments are focused in the comparison of vibration level and leakage flow rate. The results clearly shows that the anti-swirl injection balance sleeve with 0 axial degree improves the vibration characteristics. However, the anti-swirl injection balance sleeve with 30 degree aggravates the vibration characteristics. In the standpoint of leakage performance, both anti-swirl injection balance sleeves show the better result than the original balance sleeve.

• The Korean Journal of Physiology and Pharmacology
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• v.2 no.4
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• pp.503-510
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• 1998

Effects of cadmium exposure on renal $Na^+$ and $K^+$ transports were studied in rats. During the course of cadmium treatment (2 mg Cd/kg/day, s.c. injections for 3 weeks) renal tubular transports of $Na^+$ and $K^+$ were evaluated by lithium clearance technique. During the early phase (first week) of cadmium treatment, urinary $Na^+$ excretion decreased drastically and this was due to an increased $Na^+$ reabsorption both in the proximal and distal nephrons. During the late phase (third week) of cadmium treatment, filtered $Na^+$ load was decreased by reduction in GFR, but the renal $Na^+$ excretion returned to the control level due to impaired $Na^+$ transport in the proximal tubule. Urinary excretion of $K^+$ did not change during the early phase, but it rose markedly during the late phase of cadmium treatment. These results indicate that a light cadmium intoxication induces a $Na^+$ retention, and a heavy intoxication results in a $K^+$ loss. Possible mechanisms for these changes are discussed.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.12 no.8
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• pp.632-638
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• 2002

As the tangential flow inside the clearance of tribo elements such as bearings and seals is increased as the shaft speed increases, the system stability will be decreased due to the increment of the instability parameter. To reduce the tangential flow inside the clearance of the balance sleeve, anti-swirl injection mechanism is applied. The balance sleeve is used in resisting the axial force induced by impeller in high pressure multi-stage pump. In this paper, total three cases are experimentally investigated; original balance sleeve, anti-swirl injection balance sleeve with 0 axial degree and anti-swirl injection balance sleeve with 30 axial degree. Experiments are focused in the comparison of vibration level and leakage flow rate. The results clearly shows that the anti-swirl injection balance sleeve with 0 axial degree improves the vibration characteristics. However, the anti-swirl injection balance sleeve with 30 degree aggravates the vibration characteristics. In the standpoint of leakage performance, both anti-swirl injection balance sleeves show the better result than the original balance sleeve.

• YAKHAK HOEJI
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• v.26 no.4
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• pp.197-208
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• 1982

In this study attemps were made to obtain evidence as to the action of Mori Radicis Cortex on the renal' function of anesthetized mongrel dogs. 1. A light brown powder isolated from Mori Radicis Cortex (MRC) by a slight modification of Tanemura's method, when given intravenously in doses ranging 0.5 to 5.0mg/kg, elicited diuresis with the increase of positive water clearance and amounts of $Na^{+}$ and $K^{+}$ excreted in the urine. At this time the glomerular filtration rate, renal plasma flow and osmolar clearance were not observed to have any significant changes. This diuresis was augmented in process of time and its maximum effect was exhibited about 30 minutes after administration of MRC. 2. The MRC, when administered into a intra carotid artery, responded promptly with diuresis and natriuresis at a level too small to effect renal functions when administered intravenously. In this experiment the patterns of changes of renal function were the patterns of changes of renal function were the same as those of the above intravenously administered experiment. 3. When infused directly into a renal artery, the MRC exhibited little effect on either kidney. 4. During water diuresis, the MRC did not elicit diuretic action or significant changes in renal functions. The above observations suggest that the diuresis of MRC is brought about by the inhibition of the release of antidiuretic hormone with the mechanism facilitating the excretion of $Na^{+/}$ and $K^{+}$ in urine.

• Design & Manufacturing
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• v.15 no.4
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• pp.51-56
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• 2021

Piercing is the process of shearing a circular hole in sheet metal, whose high shear force makes it difficult to secure the durability of tools. In addition, uneven clearance between tools due to poor alignment of the piercing punch causes accelerated die wear and breakage of the tool. This study reviewed the feasibility of in-situ determining alignment failure during the piercing process by analyzing the signal deviation of a bolt-type piezo sensor installed inside the tool whose alignment level was controlled. Finite element analysis was performed to select the optimal sensor location on the piercing tool for sensitive detection of process signals. A well-aligned piercing process results in uniform deformation in the circumferential direction, and shearing is completed at a stroke similar to the sheet thickness. Afterward, a sharp decrease in shear load is observed. The misaligned piecing punch leads to a gradual decrease in the load after the maximum shear load. This gradual decrease is due to the progressive shear deformation that proceeds in the circumferential direction after the initial crack occurs at the narrow clearance site. Therefore, analyzing the stroke at which the maximum shear load occurs and the load reduction rate after that could detect the misalignment of the piercing punch in real-time.

• Design & Manufacturing
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• v.16 no.4
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• pp.46-51
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• 2022

The piercing process of creating holes in sheet metals for mechanical fastening generates high shear force. Real-time monitoring technology could predict tool damage and product defects due to this severe condition, but there are few applications for piercing high-strength aluminum. In this study, we analyzed the load signal to predict the punch's wear level during the process with a piezoelectric sensor installed piercing tool. Experiments were conducted on Al6061 T6 with a thickness of 3.0 mm using piercing punches whose edge angle was controlled by reflecting the wear level. The piercing load increases proportionally with the level of tool wear. For example, the maximum piercing load of the wear-shaped punch with the tip angle controlled at 6 degrees increased by 14% compared to the normal-shaped punch under the typical clearance of 6.7% of the aluminum piercing tool. In addition, the tool wear level increased compression during the down-stroke, which is caused by lateral force due to the decrease in the diameter of pierced holes. Our study showed the predictability of the wear level of punches through the recognition of changes in characteristic elements of the load signal during the piercing process.

• Biomolecules & Therapeutics
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• v.24 no.2
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• pp.199-205
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• 2016

This study aimed to investigate the in vivo relevance of P-glycoprotein (P-gp) in the pharmacokinetics and adverse effect of phenformin. To investigate the involvement of P-gp in the transport of phenformin, a bi-directional transport of phenformin was carried out in LLC-PK1 cells overexpressing P-gp, LLC-PK1-Pgp. Basal to apical transport of phenformin was 3.9-fold greater than apical to basal transport and became saturated with increasing phenformin concentration ($2-75{\mu}M$) in LLC-PK1-Pgp, suggesting the involvement of P-gp in phenformin transport. Intrinsic clearance mediated by P-gp was $1.9{\mu}L/min$ while passive diffusion clearance was $0.31{\mu}L/min$. Thus, P-gp contributed more to phenformin transport than passive diffusion. To investigate the contribution of P-gp on the pharmacokinetics and adverse effect of phenformin, the effects of verapamil, a P-gp inhibitor, on the pharmacokinetics of phenformin were also examined in rats. The plasma concentrations of phenformin were increased following oral administration of phenformin and intravenous verapamil infusion compared with those administerd phenformin alone. Pharmacokinetic parameters such as $C_{max}$ and AUC of phenformin increased and CL/F and Vss/F decreased as a consequence of verapamil treatment. These results suggested that P-gp blockade by verapamil may decrease the phenformin disposition and increase plasma phenformin concentrations. P-gp inhibition by verapamil treatment also increased plasma lactate concentration, which is a crucial adverse event of phenformin. In conclusion, P-gp may play an important role in phenformin transport process and, therefore, contribute to the modulation of pharmacokinetics of phenformin and onset of plasma lactate level.

• The Journal of the Korea Contents Association
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• v.14 no.6
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• pp.255-261
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• 2014

The generation amount of radioactive waste has been rapidly increased by increase of the usage of radioisotope source in medical field. Especially, the use of the radioactive source of I-131 with short half-life of 8.02 days used in treatment of thyroid has been increased, and all of the wastes concerned have been disposed by means of the self-disposal method. IAEA proposed criteria for clearance level of waste which depends on the individual (10 ${\mu}Sv/y$) and collective dose (1 man-Sv/y), and concentration of each nuclide (IAEA Safety Series No 111-P-1.1, 1992 and IAEA RS-G-1.7, 2004). In this study, various radioactive wastes in medical fields are collected and measured for establishing the disposal methods and procedures of radioactive wastes. In addition, comparison evaluation of decay storage period between the half-life which was calculated by attenuation curve based on real measurement and analytical half-life is considered. With comparing the theoretical half-life and the effective half life(7.72 days) which was based on the decay equation of measured data, it is resulted in the theoretical half-life is longer than effective half-life. The storage period of radioactive waste for self-disposal may be curtailed. The result of this study will be proposed as ISO standard.