• Title/Summary/Keyword: City Center

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A Study on the Neighborhood Street Characteristics for Residential Regeneration in Original Part of Seongnam City (성남기성시가지 주거지재생을 위한 생활가로 특성 연구)

  • Lee, Gi-Cheol;Lee, Young
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.1
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    • pp.23-32
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    • 2018
  • This study starts from the architectural and urban interest to integrate the daily life and behavior of residents in the city of Seongnam and to sustain the community. A fixed abode is something that can not be separated from the place and should be approached from a comprehensive perspective reflecting the physical and social conditions of the region. Although residential neighborhoods have a residential walking range, which has a steep slope, it has been formed in the suburbs of the residential area where commercial facilities are activated organically. The humanities and social organizations of the residents are integrated with the physical space and act as constituent factors of major cities. This is an attempt to suggest improvement and activation of existing cities based on their daily lives, rather than destroying cities and creating new ones. Also, it is proposed to 'Neighborhood Street' as an indicator of a uniform urban renewal plan for existing urban regeneration projects. Based on the definition of the city of living in the city, the center of the city will be located in the center of the city, and it will be the center of the city's bustling streets.

The Evaluation and Analysis of Structure of Biotope of City Center Area - In the case of Daegu district - (도시 중심부 지역의 비오톱 구조분석 및 평가 - 대구광역시 중구 사례지를 중심으로 -)

  • Ra, Jung-Hwa;Do, Hu-Jo
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.6 no.5
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    • pp.9-20
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    • 2003
  • The purpose of this study is to construct a database for landscape ecological planning with evaluation and analysis of structure of biotope of city center area for the preservation of species and biotope examining Jung-gu district of Daegu Metropolitan City which is the most extremely and rapidly urbanizing area. The assumption of this study is that the biotope structure of a city center area would be different from the other city area. The results of this study were as follows. 1) The results of the biotope type classification is that there were 11 biotope type groups and 41 detailed biotopes. 2) The primary evaluation is the process for grading general value of classified biotope types, and the result of primary evaluation is that there were 5 biotope types that were greater than third grade besides the biotope type of artificial riverbank with abundant green high water level land. The first grade of biotope type have not appeared in this area, however the fifth grade of biotope type have appeared total of 19 biotope types with the biotope type of the general shopping area with scarce green fields. 3) The secondary evaluation is the process for searching biotopes which are special value, and the result of secondary evaluation is that there were 2 biotopes for la, 7 biotopes for 1b, 2 biotopes for 2a, 1 biotope for 2b and there was no biotope for 2c, and for example, la is the large area that has many magor biotope site in terms of the living space. 4) Finally. scientific method for biotope type classification, the derailed investigation plan of high value biotope and the improvement plan based on the biotope map of city center area must be continued.

EGF Reverses Multi-drug Resistance via the p-ERK Pathway in HepG2/ADM and SMMC7721/ADM Hepatocellular Carcinoma Models

  • Yan, Feng;Bai, Li-Ping;Gao, Hua;Zhu, Chang-Ming;Lin, Li;Kang, Xiang-Peng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2619-2623
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    • 2014
  • Aim: To investigate signaling pathways for reversal of EGF-mediated multi-drug resistance (MDR) in hepatocellular carcinoma (HCC) models. Materials and Methods: HCC MDR cell strain HepG2/adriamycin (ADM) and SMMC7721/ADM models were established using a method of exposure to medium with ADM between low and high concentration with gradually increasing concentration. Drug sensitivity and reversal of multi-drug resistance by EGF were determined and the cell cycle distribution and apoptosis were analyzed by flow cytometry. Phosphorylation of ERK1, ERK2, ERK5 and expression of Bim were detected by Western blotting. Results: The results showed that HepG2/ADM and SMMC7721/ADM cells were resistant not only to ADM, but also to multiple anticancer drugs. When used alone, EGF had no anti-tumor activity in HepG2/ADM and SMMC7721/ADM cells in vitro, while it increased the cytotoxicity of ADM. EGF induced cell apoptosis and G0/G1 phase cell cycle arrest in HepG2/ADM And SMMC7721/ADM cells, while enhancing activity of p-ERKs and up-regulated expression of BimEL. Conclusions: EGF might enhance the chemosensitivity of HepG2/ADM and SMMC7721/ADM cells via up-regulating p-ERKs and BimEL protein.

Fragility Fractures of the Pelvis and Sacrum: Current Trends in Literature

  • Erick Heiman;Pasquale Jr. Gencarelli;Alex Tang;John M. Yingling;Frank A. Liporace;Richard S. Yoon
    • Hip & pelvis
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    • v.34 no.2
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    • pp.69-78
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    • 2022
  • Fragility fractures of the pelvis (FFP) and fragility fractures of the sacrum (FFS), which are emerging in the geriatric population, exhibit characteristics that differ from those of pelvic ring disruptions occurring in the younger population. Treatment of FFP/FFS by a multidisciplinary team can be helpful in reducing morbidity and mortality with the goal of reducing pain, regaining early mobility, and restoring independence for activities of daily living. Conservative treatment, including bed rest, pain therapy, and mobilization as tolerated, is indicated for treatment of FFP type I and type II as loss of stability is limited with these fractures. Operative treatment is indicated for FFP type II when conservative treatment has failed and for FFP type III and type IV, which are displaced fractures associated with intense pain and increased instability. Minimally invasive stabilization techniques, such as percutaneous fixation, are favored over open reduction internal fixation. There is little evidence regarding outcomes of patients with FFP/FFS and more literature is needed for determination of optimal management. The aim of this article is to provide a concise review of the current literature and a discussion of the latest recommendations for orthopedic treatment and management of FFP/FFS.

The Analysis of u-City Management and Control service for Efficient City Integration management center (효율적인 도시 통합 운영센터를 위한 u-City 관제 서비스 분석)

  • Eom, Tae-Young;Lee, Sung-Hwan;Kim, Woo-Ju
    • 한국IT서비스학회:학술대회논문집
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    • 2009.05a
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    • pp.106-109
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    • 2009
  • u-City 통합운영센터는 u-City 운영의 가장 기본이면서 기존 도시와 u-City를 차별화 하는 중요한 요소이다. 이에 따라 도시통합운영센터에서 효과적으로 제공해야 하는 u-City 서비스 선정을 위한 분류가 마련되어야 한다. 본 연구에서는 u-City 도시통합운영센터의 중요 기능인 관제에 해당하는 서비스들을 분류하고 향후 u-City 도시통합운영센터를 구축할 때 관제 관점에서 고려되어야 할 서비스들에 대하여 제언하고자 한다.

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Local Community Development Model Building Study after Radioactive waste disposal facility Siting on GyeongJu (방사성 페기물 처분장 입지 후 지역 변화 모델 구축)

  • Oh, Young-Min;Yu, Jae-Kook
    • Korean System Dynamics Review
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    • v.7 no.1
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    • pp.119-146
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    • 2006
  • City of Gyeongju's referendum finally offered the long-waited low-level radioactive waste disposal site in November 2005. Gyeongju's positive decision was due to the various economic rewards and incentives the national government promised to the city. 300 million won for an accepting bonus, 8.5 billion won, annual revenue fro the entry quantity of waste into the city's disposal site, the location of the headquarter building of the Korean Hydro and Nuclear Power Co., and the accelerator research center. All of the above will affect the city's infrastructure and the citizens' economic and cultural lives. Population, land use, economic structure, environment and quality of life will be affected. Some will be very positive, and some will be positive. This research project will see the future of the city and forecast the demographic, economic, physical and environmental changes of the city via computer simulation's system dynamics technique. This kind of simulation will help City of Gyeongju's what to prepare for the future. The population forecasting of the year 2026 will be 289,069 with the waste disposal site, and 279,131 without the waste disposal site in Gyeongju. The waste disposal site and the relocation of the company headquarters and location of the accelerator research center will attract 9,938 individuals more with 511 manufacturing shops and 1944 service jobs. The population increase will bring 3,550 more houses constructed in the city. Land use will also be affected. More land will be developed. However, mad, water plant and waste water plant will not be expanded as much. The city's financial structure will be expanded, due to the increased revenues from the waste disposal site, and property tax revenues from the middle-class employees of the company, and the high-powered scientists and technologists from the accelerator research center. All in an, the future of the city will be brighter after operating the nuclear waste disposal site inside the city.

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A Study on Using U-Service to Strengthen Urban Competitiveness

  • Shin, Jin-Dong;Lee, Jae-Won;Lee, Sang-Hun;Kim, Hyong-Bok
    • Spatial Information Research
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    • v.17 no.4
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    • pp.417-430
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    • 2009
  • This study examined correlations between U-Service for U-City and assessment indicators for urban competitiveness. The results of this study show that U-Service is used as a means of strengthening urban competitiveness in six types of cities, despite the differences in degree of contribution. The proper use of U-Service in Safety & Health City and Vitality (Economy) City has significantly contributed to strengthening the competitiveness of such cities. Of the assessment items for urban competitiveness, common items and Culture City type show that U-Service has not contributed much to strengthening urban competitiveness. The analysis shows that because common items are part of the assessment items for urban policies, these items are not suitable to the character of a U-City that implements U-Service through intelligent physical facilities. On the other hand, U-Service related to the Culture City type is relatively less developed. This study found out that U-Service could be used to reinforce urban competitiveness.

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Evaluation of Insecticidal Activity of Plant Extracts against the Diamondback Moth, Plutella xylostella (Lepidoptera: Plutellidae) on Vegetable Plant (배추좀나방(Plutella xylostella)에 대한 식물추출물의 살충력 평가)

  • Choi, I-Jin;Kwon, Hyuk-Hyun;Lee, Han-Ho;Son, Hyoung-Gi;Hong, Sang-Kil;Kang, Jong-Woon;Park, Yu-Soon
    • Korean Journal of Plant Resources
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    • v.26 no.1
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    • pp.19-25
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    • 2013
  • This study focused on the usefulness of plant extracts for a city organic farm. Insecticidal activity of 8 plant species, plants crude extracts by ethanol and water, against third instar larvae (susceptible strain) of Plutella xylostella was evaluated in this study. Ethanol(25%) extracts of plant materials had better insecticidal activity than water extracts at the room temperature. Insecticidal activity were investigated by leaf disc spray method. Five plant extracts (Capsicum annuum, Chelidoniun majus, Leonurus sibiricus, Coptis japonica, Mentha piperascens) showed over 50% insecticidal activity to P. xylostella at the concentration of $1500mg{\cdot}L^{-1}$. Extract of C. annuum showed the highest insecticidal activity (83.3%) against P. xylostella. Phytotoxicity was not observed on Raphanus sativus and Brassica campestris with spray application. Seed germination and growth of two plants were not affected. Extract of C. japonica revealed 73.3% control efficacy against P. xylostella of R. sativus and showed 70% control efficacy against those of B. campestris, respectively, in plastic house. Insecticidal activity against various insects was observed in C. japonica extract as 87.4% for R. sativus and 74.3% for B. campestris in the field. These results suggested that extracts of C. annuum, C. japonica showed the highest insecticidal activity, and could be used as city farm insecticides for organic farming.