• 대한의용생체공학회:의공학회지
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• 제35권5호
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• pp.151-159
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• 2014

Computed tomography (CT) is one of the most widely used medical imaging modality. However, substantial x-ray dose exposed to the human subject during the CT scan is a great concern. Region-of-interest (ROI) CT is considered to be a possible solution for its potential to reduce the x-ray dose to the human subject. In most of ROI-CT scans, the ROI is set to a circular shape whose diameter is often considerably smaller than the full field-of-view (FOV). However, an arbitrarily shaped ROI is very desirable to reduce the x-ray dose more than the circularly shaped ROI can do. We propose a new method to make a non-circular convex-shaped ROI along with the image reconstruction method. To make a ROI with an arbitrary convex shape, dynamic collimations are necessary to minimize the x-ray dose at each angle of view. In addition to the dynamic collimation, we get the ROI projection data with slightly lower sampling rate in the view direction to further reduce the x-ray dose. We reconstruct images from the ROI projection data in the compressed sensing (CS) framework assisted by the exterior projection data acquired from the pilot scan to set the ROI. To validate the proposed method, we used the experimental micro-CT projection data after truncating them to simulate the dynamic collimation. The reconstructed ROI images showed little errors as compared to the images reconstructed from the full-FOV scan data as well as little artifacts inside the ROI. We expect the proposed method can significantly reduce the x-ray dose in CT scans if the dynamic collimation is realized in real CT machines.

• Journal of Information Processing Systems
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• 제12권1호
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• pp.83-99
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• 2016

The latest research on the image-based fingerprint matching approaches indicates that they are less complex than the minutiae-based approaches when it comes to dealing with low quality images. Most of the approaches in the literature are not robust to fingerprint rotation and translation. In this paper, we develop a robust fingerprint matching system by extracting the circular region of interest (ROI) of a radius of 50 pixels centered at the core point. Maximizing their orientation correlation aligns two fingerprints that are to be matched. The modified Euclidean distance computed between the extracted orientation features of the sample and query images is used for matching. Extensive experiments were conducted over four benchmark fingerprint datasets of FVC2002 and two other proprietary databases of RFVC 2002 and the AITDB. The experimental results show the superiority of our proposed method over the well-known image-based approaches in the literature.

• Imaging Science in Dentistry
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• 제31권2호
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• pp.85-91
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• 2001

Purpose: To evaluate the effect of the slice thickness and the size of region of interest (ROI) on CT number using quantitative CT phantom Materials and Methods: The phantom containing 150 mg/cc, 75 mg/cc and 0 mg/cc calcium hydroxyapatite was scanned with 1, 3, 5 and 10 mm slice thicknesses by single energy quantitative computed tomography (QCT). CT numbers were measured on center position of the phantom. Shape of ROI was circular and sizes were 1, 3, 5, 11, 16, 21, 26 and 33 mm². ANOVA and Tukey's multiple comparison method were performed for statistical comparison of CT numbers according to different slice thicknesses. Coefficient of variation of CT number measured in each size of ROI was evaluated in same slice thickness. Results : CT numbers had statistically significant difference according to slice thicknesses (p<0.05). As the slice thickness increased, CT number also increased. As the density of phantom became lower and the size of ROI became smaller, the coefficient of variation of CT number increased. When the size of ROI was more than 11 mm² in 1 mm slice thickness, 5 mm² in 3 mm slice thickness and 3 mm² in 5 mm slice thickness, the coefficient of variation became consistent. In 10 mm slice thickness, the size of ROI had little effect on the coefficient of variation. Conclusion: CT number had variation according to the slice thickness and the size of ROI although the object was homogeneous. The slice thickness and the size of ROI are critical factors in precision of the CT number measurements.

• 한국컴퓨터그래픽스학회논문지
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• 제23권4호
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• pp.31-40
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• 2017

최근 3차원 세포 배양이 가능해 지면서 세포의 부피, 3차원 형태 등을 보다 정확하게 확인할 수 있게 되었다. 일반적으로 세포의 3차원 단층 정보는 공초점 현미경 또는 전자 현미경과 같은 특수한 현미경을 이용하여 관찰 해야 한다. 그러나 공초점 현미경은 일반 현미경에 비해 비용이 비싸며, 촬영 시간이 오래 걸린다. 따라서 일반적으로 사용되는 광학 현미경으로 세포의 3차원 형태복원을 하는 방법이 필요하다. 본 논문에서는 다초점 형광 영상을 기반으로 영상의 추정된 초점 값(focus estimator value)을 이용해 세포를 3차원으로 형태 복원하는 방법을 제안한다. 먼저 3차원으로 배양된 세포를 광학 현미경으로 초점을 변경 하면서 다초점 영상들을 촬영한다. 이후 영상에서 circular Hough transform을 이용하여 세포 군집의 대략적인 위치를 ROI(Region Of Interest)로 정한다. 획득한 ROI에 MSBF(Modified Sliding Band Filter)를 적용하여 ROI 내에 세포 군집의 외곽선을 추출하고, 추출된 외곽선을 기준으로 추정 초점 값을 구한다. 계산된 초점 값과 현미경의 NA(Numerical Aperture)을 이용하여 깊이를 고려한 세포 군집의 외곽선을 추출하고 추출된 외곽선을 통해 세포들을 3차원으로 형태 복원한다. 복원 결과는 세포 영상의 in-focus가 된 부분들을 하나로 합친 영상과 비교하여 검증한다.

• Applied Microscopy
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• 제44권4호
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• pp.138-143
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• 2014

Transmission electron microscope (TEM) is an excellent tool for studying the structure and properties of nanostructured materials. As the development of $C_s$-corrected TEM, the direct analysis of atomic structures of nanostructured materials can be performed in the high-resolution transmission electron microscopy (HRTEM). Especially, fast Fourier transform (FFT) technique in image processing is very useful way to determine the crystal structure of HRTEM images in reciprocal space. To apply FFT technique in HRTEM analysis in more reasonable and friendly manner, we made a new circular region of interest (C-ROI) FFT script and tested it for several HRTEM analysis. Consequentially, it was proved that the new FFT application shows more quantitative and clearer results than conventional FFT script by removing the streaky artifacts in FFT pattern images. Finally, it is expected that the new FFT script gives great advantages for quantitative interpretation of HRTEM images of many nanostructured materials.

• 전자공학회논문지SC
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• 제48권6호
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• pp.57-62
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• 2011

본 논문에서는 초전도 자석의 자장 균일도를 개선하기 위한 방법으로 3가지 형태의 magnet 모델을 제안하고 각각의 자석 형태에 대하여 같은 세기의 자장을 (Magnet field strength) 가질 경우에 최소전력 방식으로 최적화된 전류 분포에 해당하는 coil wire의 길이, 그리고 해당 조건에서의 자장의 불균일도를 시뮬레이션을 통하여 비교, 분석하였다. 구성된 3가지 magnet type을 동일한 조건 (계산 점의 개수 18개, 20cm DSV)에 대해서 wire길이와 main field inhomogeneity를 비교하였으며, 이러한 시뮬레이션 결과를 통하여 얻을 수 있는 결론은 계산점의 수가 적을수록 wire의 길이는 짧아지나 field inhomogeneity는 높아진다는 것이다. 즉, Magnet shim을 수행할 경우 계산점을 줄이는 방법으로는 짧은 wire의 길이와 main field homogeneity를 동시에 만족하도록 최적화 하는 것이 거의 불가능함을 의미하는 것이다. 그러나 DSV를 줄였을 경우에 계산점을 줄였을 때에 비해 우수한 결과 값을 얻을 수 있었다. 결론적으로 공간적으로 개방되어 있는 magnet model의 경우 계산점을 줄여 shimming을 진행할 경우 동일한 imaging region의 크기에 대해 더 많은 전류(또는 wire 길이)가 필요하고 field 균일도도 떨어졌으나 작은 ROI를 대상으로 영상을 얻는 경우 유용하게 사용될 수 있다.

• 한국임상보건과학회지
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• 제3권1호
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• pp.276-289
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• 2015

Purpose. To efficiently manage hospitals, this study aims to analyze the general characteristics, common-type balance sheet, common-type profit and loss statement and financial ratio of a tertiary general hospital and use the results as basic data for future hospital development by comprehending causes for problems and analyzing hospital management. Methods. By using information about a tertiary general hospital, located in A Metropolitan City, provided through Alio (www.alio.go.kr), a public organization information provider, Health Insurance Review & Assessment Service, and Ministry of Health and Welfare, this study used data during 3 years(2011 to 2013) by analyzing the general characteristics, common-type balance sheet, common-type profit and loss statement, industrial mean ratio and financial ratio of hospitals. Results. This study came to the following conclusions through the general characteristics, common-type balance sheet, common-type profit and loss statement, industrial mean ratio, financial ratio, circular chart and ROI by analyzing the data from 2011 to 2013. Conclusions. Overall, A Tertiary General Hospital showed an increase in fixed cost due to the construction of J Hospital and even in the size of capital and assets. It also showed an increase in medical profit, but the increase of its medical cost was higher, resulting in a financial loss. Especially, this hospital showed a slight decrease in net profit, featuring a reduction in inventory turnover. When the management of A Tertiary General Hospital was predicted based on such features, this hospital is expected to improve its profit structure through the opening of J Hospital, and it is necessary for this hospital to increase and sustain the turnover rate of inventories accumulated by managing them better.

• 대한디지털의료영상학회논문지
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• 제13권3호
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• pp.111-115
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• 2011

PET/CT(Positron Emission Tomography/Computed Tomography) is an examination combining morphological and functional information in one examination. The purpose of this study is to see the lowest CT dose for attenuation correction in the PET/CT maintaining good image quality when considering CT scan dose to the patients. We injected $^{18}F$-FDG and water into the cylinder shaped phantom, and obtained emission images for 3 mins and transmission images(140 kVp, 8 sec, 10~200 mA for transmission images), and reconstructed the images to PET/CT images with Iterative method. Data(Maximum, Minimum, Average, Standard Deviation) were obtained by drawing a circular ROI(Region Of Interest) on each sphere in each image set with Image J program. And then described SD according to the CT and PEC/CT images as graphes. Through the graphes, we got the relationships of mA and quality of images. SDs according to CT graph were 16.25 at 10 mA, 7.26 at 50 mA, 5.5 at 100 mA, 4.29 at 150 mA, and 3.83 at 200 mA, i.e. the higer mA, the better image quality was presented. SDs according to PET/CT graph were 1823.2 at 10 mA, 1825.1 at 50 mA, 1828.4 at 100 mA, 1813.8 at 150 mA, and 1811.3 at 200 mA. Calculated SDs at PET/CT images were maintained. This means images quality is maintained having nothing to do with mA of high and low.

• Imaging Science in Dentistry
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• 제48권1호
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• pp.45-49
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• 2018

Purpose: The aim of this study was to evaluate the quantitative strain elastography of tongue carcinoma using intraoral ultrasonography. Materials and Methods: Two patients with squamous cell carcinoma (SCC) who underwent quantitative strain elastography for the diagnosis of tongue lesions using intraoral ultrasonography were included in this prospective study. Strain elastography was performed using a linear 14 MHz transducer (Aplio 300; Canon Medical Systems, Otawara, Japan). Manual light compression and decompression of the tongue by the transducer was performed to achieve optimal and consistent color coding. The variation in tissue strain over time caused by the compression exerted using the probe was displayed as a strain graph. The integrated strain elastography software allowed the operator to place circular regions of interest (ROIs) of various diameters within the elastography window, and automatically displayed quantitative strain (%) for each ROI. Quantitative indices of the strain (%) were measured for normal tissues and lesions in the tongue. Results: The average strain of normal tissue and tongue SCC in a 50-year-old man was 1.468% and 0.000%, respectively. The average strain of normal tissue and tongue SCC in a 59-year-old man was 1.007% and 0.000%, respectively. Conclusion: We investigated the quantitative strain elastography of tongue carcinoma using intraoral ultrasonography. Strain elastography using intraoral ultrasonography is a promising technique for characterizing and differentiating normal tissues and SCC in the tongue.

• 한국방사선학회논문지
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• 제16권6호
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• pp.673-680
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• 2022

본 연구에서는 PLA를 기반으로 알루미늄, 나무, 구리, 카본, 대리석이 각각 20% 함유된 재질들의 CT number를 분석하고 영상에 어떠한 영향을 미치는지 분석하고자 하였다. 보급형 3D 프린터를 이용하여 5×30×30 ㎣(두께×직경×높이)의 원기둥 모양 팬텀을 제작하였다. 관전압을 80, 100, 120 kV로 변화시키고, 관전류초를 100, 200 mAs로 변화시켜 테이블 중앙에 놓인 팬텀을 총 6가지 조건으로 횡단 스캔하였다. Image J를 이용하여 원형의 ROI를 설정하고 물질부 CT number의 정량값과 주변부 CNR의 정량값을 구하였다. 물질부의 CT number 평균값은 PLA-나무20%, PLA-대리석20%, PLA-카본20%, PLA-100%, PLA-알루미늄20%, PLA-구리20% 순으로 높아졌고(p<0.05), kV 증가에 따른 CT number는 음의 상관성을 확인하였다. 주변부의 CNR값은 PLA-대리석20%, PLA-구리20%, PLA-카본20%, PLA-나무20%, PLA-알루미늄20%, PLA-100% 순으로 증가 됨을 확인하였다(p<0.05). 각 재료별 HU 값과 유사한 인체 장기는 PLA-구리20%는 치밀골, PLA-알루미늄20%는 해면골, PLA-100%는 응고된 혈액, PLA-카본20%와 PLA-대리석20%는 간, 근육, 비장, PLA-나무20%는 지방과 유사한 값이었다. 또한 모든 재료에서 필라멘트 주변부 영상을 흐리게 하는 흐림 현상을 확인하였고 특히 PLA-100%에서 영상 주변부 흐림 현상이 가장 많은 것을 확인하였다. 따라서 의료용팬텀 제작의 재질을 선정할 때 목표 장기의 HU 값을 반영하고, 팬텀 주변부의 흐림 현상을 고려하는 것이 바람직하다고 판단하며 본 연구가 기초 자료를 제공할 수 있을 것이라 사료된다.