• 한국약용작물학회:학술대회논문집
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• 2011.04a
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• pp.286-287
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• 2011

• Toxicological Research
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• v.11 no.2
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• pp.309-313
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• 1995

The aim and objective of this study are to carry out the liver protective activities against the $CCl_4$ intoxication in mice with some Iranian medicinal plants traditionally used for liver injuries. The methanol extracts of Cichorium intybus, Lactuca scarJoia, Eucalyptus camadulensis were evaluated. With various doses of these plants, liver protective activities were performed after $CCl_4$ administration to mice. The serum aminotransferases activites, liver sizes, and histopatological examinations of liver were studied. At a dose of 50 mg/ kg, all three plants were able to protect liver damages induced by $CCl_4$.

• Natural Product Sciences
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• v.5 no.4
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• pp.155-158
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• 1999

Several biological activities of extracts from roots of Cichorium intybus Linne (Compositae) were studied in this paper. The antiinflammatory activity of the methanol extract of this root was investigated against carrageenin induced edema in rat‘s hind paw. Significant inhibitory effects were observed at the dose of 1,000 mg/kg and were compared with aspirin as a control. The hepatoprotective activities of the methanol extract, ethylacetate and butanol fraction were studied on mice whose livers are damaged by $CCl_4$. The serum transaminase activities (ALT, AST) were reduced at the dose of 1,000 mg/kg of the methanol extract, 500 mg/kg of ethylacetate and butanol fraction, respectively. The bile juice secretion was also increased significantly from each fraction. The antidiabetic activity was examined on strepto-zotocin-induced diabetic rats with methanol extract. Methanol extract gave a significant reduction of blood glucose levels in 1 week and 3 weeks.

• Proceedings of the Plant Resources Society of Korea Conference
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• 1995.01a
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• pp.27-27
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• 1995

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2004.12a
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• pp.119-120
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• 2004

• Proceedings of the PSK Conference
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• 2000.04a
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• pp.148.1-148.1
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• 2000

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.04a
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• pp.58-58
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• 2022

• Journal of Bio-Environment Control
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• v.15 no.4
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• pp.417-420
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• 2006

To investigated the dormancy of chicory (Cichorium intybus L.) for production of high quality rootstocks, growth characteristics and abscisic acid (ABA) contents was conducted. The accumulation hours below $5^{\circ}C$ in field was increased slowly from October 7 to December 3, but there after increased largely. The rootstock weights was increased from the end of October to December 3, there after was not changed to December 3. ABA contents within the rootstock was not changed from October 7 to December 3, and there was suddenly increased for two weeks to December 24. As results of the sudden changed date of accumulation hours below $5^{\circ}C$, stopped date and period of rootstock growth, and sudden changed period of ABA contents, chicory has internal dormancy for two weeks from December 3 and low temperature requirement hours for the dormancy breaking is about 240.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2000.10b
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• pp.76-76
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• 2000

• Advances in Traditional Medicine
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• v.6 no.3
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• pp.196-201
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• 2006

The efficacy of alcoholic extract of Kasni (Cichorium intybus L.) to control hepatic damage induced by aflatoxin $B_1$ was explored in Swiss albino mice. Aflatoxin $B_1$ was administered orally to the mice with a daily dose of $66.6{\mu}g/kg$ body weight till three months. A signifi-cant increased in thio barbituric acid reactive substances (TBARS) levels with concomitant reduction in enzymatic (glutathione-s-transferase, glutathione peroxidase, superoxide dismutase, and catalase) and nonenzymatic (reduced glutathione) antioxidants were shown in aflatoxin treated group of mice. However, there was a significant reduction in increased TBARS levels and elevation in enzymatic. and non enzymatic antioxidant levels in group of mice which received alcoholic extract of kasni (300 mg/kg bw / day) along with aflatoxin. Histopathological analysis of liver samples also confirmed the hepatoprotective effect of kasni extract. These results suggest that kasni shows hepatoprotective effect against aflatoxin $B_1$ induced hepatic damage in mice.