• Journal of Pharmacopuncture
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• v.6 no.3
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• pp.49-55
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• 2003

This study was undertaken to define the effect of ChungSangSaWhaTang on the norepinephrine-induced arterial contraction and the mechanism of ChungSangSaWhaTang-induced relaxation. In order to investigate the effect of ChungSangSaWhaTang on contracted rabbit carotid arterial strips, transverse strips with intact or damaged endothelium were used for the experiment using organ bath. To analyze the mechanism of ChungSangSaWhaTang-induced relaxation, ChungSangSaWhaTang extract infused into contracted arterial strips induced by norepinephrine after treatment of indomethacin, $N_{\omega}$-nitro-L-arginine, or tetraethylammonium chloride. ChungSangSaWhaTang relax arterial strip with endothelium contracted by norepinephrine, but in the strips without endothelium, ChungSangSaWhaTang-induced relaxation was significantly inhibited. The endothelium-dependent relaxation induced by ChungSangSaWhaTang was decreased by the pretreatment of $N_{\omega}$-nitro-L-arginine, but it was not observed in the strips pretreated with indomethacin or tetraethylammonium chloride. We suggest that ChungSangSaWhaTang may inhibit agonist-induced contraction through the formation of nitric oxide in the vascular endothelial cells.

• The Journal of Internal Korean Medicine
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• v.12 no.2
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• pp.113-128
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• 1991

This study has been carried out to investigate Pyu-Juk ( 肺積 ), Pyu-Ong ( 肺癰 ), Pyu-Ju ( 肺疽 ), Pyu-Am ( 肺癌 ) by referring to 56 literatures. The results were obtained as follows; 1. The treatllent-method of Pyu-Juk ( 肺積 ) are Ik Ki ( 益氣 ), SuI Yem Wha ( 洩陰火 ), So Juk ( 消積 ), Wha Juk ( 化積 ), Son Juk ( 損積 ), Ma Juk ( 摩積 ) Jo Chil Gi ( 調七氣 ), and herbs are Sik Bun Tang ( 息賁湯 ), Sik Bun Hwan ( 息賁丸 ), O Juk Hwan ( 五積丸 ), Ban ha Tang ( 半夏湯 ), Gil Gyung Tang ( 桔梗湯 ), Dae Chil Gi Tang ( 大七氣湯 ), Chil Gi Hwan ( 七氣湯 ) , Ga Gam Sik BlDl Hwan ( 加減息賁丸 ), Bil Rang San ( 檳郞散 ). 2. The treatment-method of Pyu-Ong ( 肺癰 ) Yang pyu ( 養肺 ), Yang Hyul ( 養血 ), Yang Gi ( 陽氣 ), Chung Geam Youn Pye ( 淸金潤肺 ), Hal Dam Bae Nong ( 豁痰排膿 ), Saeng Gi ( 生肌 ), herbs are Gil Gyung Tang ( 桔梗湯 ), Jung Ryuk Dae Jo Sa Pyu Tang ( ??大棗瀉肺湯 ), Chung Geom Wy Gyung Tang ( 千金 葦莖湯 ) Hwang Gi tang ( 黃嗜湯 ), Hyun Sam Chung Pyu Eum ( 玄蔘淸肺飮 ), Sip Mi Hwan ( 十味丸 ), Gil Gyung Baek San ( 桔梗白散 ), So Hong Eum ( 消膿飮 ), Sam Gi Bo Pyu Tang ( 蔘嗜補肺湯 ), sam Chul Gun Bi Tang ( 蔘朮健脾湯 ), Chung Pyu Gil Gyung Tang ( 淸肺桔梗湯 ), Yu Sung Hwan ( 如聖丸 ). 3. The treatment-method of Pyu-Ju ( 肺疽 ) are Be Bi ( 補脾 ), Bo Pyu ( 補肺 ), herbs are Hwang Gi Gum Jung Tang( 黃嗜補裨湯 ), lnSamBoPyuSan (人蔘補肺散) 4. The treatment-method of Pyu-Am ( 肺癌 ) are Bal Han ( 發汗 ), Chung Yul Hae Dok ( 淸熱解毒 ), Gang Hwa Do Dam ( 降火導痰 ), Hwa Rak Hwa a ( 和絡化瘀 ) Ik Pyu ( 益肺 ), Gun Bi ( 健脾 ), Ja Eum Yun Pyu ( 滋陰潤肺 ), Gi Hu Yang Bo ( 氣虛兩補 ), herbs are Gyul Yua Hae Dok Tang ( 莖熱解毒湯 ), Gang Hwa Jae ( 降火劑 ), Chil Yul Do Dam Tang ( 治熱導痰湯 ), Chong Ho Byul Gap Tang ( 靑蒿鱉甲湯 ), Ga gam Gil Gyung Tang ( 加減桔梗湯 ), Sang Mak San ( 生脈散), Yuk Mi Ji Hwang Tang ( 六味地黃湯 ), Baek Hap Go Geum Tang ( 百合固金湯 ), Dae Be Won Jun ( 大補元煎 ), Ga Mi Jae Che Bo Pyu Tang ( 加味載體補肺湯 ).