• 제목/요약/키워드: Chronic arsenic intoxication

검색결과 2건 처리시간 0.015초

만성 비소 중독으로 의심되는 피부염 치험 1례 (A Clinical Experience of Dermatitis suspected Chronic Arsenic Intoxication)

  • 강병수;최정화;박수연;정민영;김종한
    • 한방안이비인후피부과학회지
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    • 제30권3호
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    • pp.201-210
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    • 2017
  • 만성 비소 중독으로 의심되는 피부염 환자를 양방 치료 없이 평혈음을 기본으로 한 한약과 침 치료 등 한방 단독 치료를 통하여 제반 증상을 호전시켰음을 관찰하여 보고한다.

Effect of an extract of Bauhinia variegata leaves on chronic arsenic intoxication in mice (Mus musculus): A preliminary study

  • Biswas, Surjyo Jyoti;Ghosh, Goutam
    • 셀메드
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    • 제4권3호
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    • pp.20.1-20.7
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    • 2014
  • Ethanolic leaf extract of Bauhinia variegata has been tested for its possible antioxidant potentials against sodium arsenite induced toxicity in mice. Mice were randomized into two groups of five and fifty mice. Group I consisting of 5 mice without any treatment with food and water ad libitum which served as normal control. Group II mice were fed with sodium arsenite in drinking water at 100 ppm concentration for two monthsthen they were segregated into five groups which were treated differently. Group II a mice received only arsenic as sodium arsenite with drinking water, Group II b were fed chronically 1 : 20 alcohol to distilled water (vehicle), Group II c, d, e mice were orally fed 50 mg/kg, 150 mg/kg and 250 mg/kg of B. variegata leaf extract of once daily for 15 and 30 days respectively along with arsenic. Several toxicity marker enzymes such as gamma glutamyl transferase, lactate dehydrogenase, aspartate and alanine aminotransferase, acid and alkaline phosphatase, catalase and superoxide dismutase along with haematological variables such as glucose 6-phosphate dehydrogenase, creatinine, bilirubin, haemoglobin and sugar in different groups of treated and control mice were studied. Results obtained from the in vivo experiment revealed that administration of sodium arsenite caused a significant increase in some enzymes while decrease in some. A similar trend was also observed with haematological variables. In contrast B. variegata treatment at 150 mg/kg favourably modulated these alterations and maintained the antioxidant status than other two doses i.e. 50 mg/kg and 250 mg/kg thereby making it a good candidate to be used as supportive palliating measures in arsenic induced toxicity.