• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6359-6364
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• 2015

Background: Preclinical studies have shown that the combination of an aromatase inhibitor (AI) and capecitabine in estrogen receptor (ER)- positive cell lines enhance antitumor efficacy. This retrospective analysis of a group of patients with metastatic breast cancer (MBC) evaluated the efficacy and safety of combined AI with capecitabine. Materials and Methods: Patients with hormone receptor-positive metastatic breast cancer treated between 1st January 2005 and 31st December 2010 with a combination of capecitabine and AI were evaluated and outcomes were compared with those of women treated with capecitabine in conventional dose or AI as a monotherapy. Results: Of 72 patients evaluated, 31 received the combination treatment, 22 AI and 19 capecitabine. The combination was used in 20 patients as first-line and 11 as second-line treatment. Mean age was 46.2 years with a range of 28-72 years. At the time of progression, 97% had a performance status of <2 and 55% had visceral disease. No significant difference was observed between the three groups according to clinical and pathological features. Mean follow up was 38 months with a range of 16-66 months. The median PFS of first-line treatment was significantly better for the combination (PFS 21 months vs 8.0 months for capecitabine and 15.0 months for AI). For second-line treatment, the PFS was longer in the combination compared with capecitabine and Al groups (18 months vs. 5.0 months vs. 11.0 months, respectively). Median 2 year and 5 year survival did not show any significant differences among combination and monotherapy groups. The most common adverse events for the combination group were grade 1 and 2 hand-for syndrome (69%), grade 1 fatigue (64%) and grade 1 diarrhoea (29%). Three grade 3 hand-foot syndrome events were reported. Conclusions: Combination treatment with capecitabine and AI used as a first line or second line treatment was safe with much lowered toxicity. Prospective randomized clinical trials should evaluate the use of combination therapy in advanced breast cancer to confirm these findings.

• Journal of Christian Education in Korea
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• v.62
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• pp.101-133
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• 2020

This study is an attempt to grasp the fundamental characteristics and core structures of Bibliodrama, which has recently received a lot of attention in various fields including Christian education. Bibliodrama is a guided form of process-oriented staging of biblical texts in groups with the aim of mutually opening up the text and the biography of the participants in the implementation of holistic encounters (H. Aldebert). In the background of the birth of Bibliodrama can be found the hermeneutical efforts of the biblical scholar Walter Wink who sentenced the bankruptcy of historical criticism. He laid the biblical interpretative foundation for Bibliodrama which combines Bible and body. German theologian Gerhard Marcel Martin had a new experience of seeing the Bible through body activity during his life in New York, and based on that experience he began to work on the Bibliodrama. And the New Testament scholar Tim Schramm, who focused on the TCI (themecentered interaction) movement, found the optimal methodology to embody the interaction of biblical studies in Bibliodrama. On the other hand, Peter Pitzele, who wanted to realize the Bibliodrama in the tradition of Midrash, has developed a new type of Bibliodrama (Bibliolog) that is different from the European Bibliodrama. When we put together the positions of the pioneers of Bibliodrama, it turns out that it has three fundamental characteristics: body, interaction, and the empty space of the Bible. The body refers to the personality of learners participating in the Bibliodrama. They are not passive participants, but voluntary and active participants. Interaction is realized through the dramatic way of Bibliodrama. Bibliodrama aims for a dynamic process in which hermeneutical interaction occurs. The empty space of the Bible, which Bibliodrama pays attention to, allows us to understand why the Bible is not a fixed word but a living word that is still heard today. In order to understand the Bible as the content of education, Bibliodrama liberates the text that is fixed in a literal way and gives life by paying attention to the empty space of the Bible and reading it slowly.

• Journal of the Korean Home Economics Association
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• v.44 no.9
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• pp.77-87
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• 2006

This study focused on a premarital counseling program and examined its effectiveness. The program consisted of eight sessions and was conducted with twelve premarital couples: six in the experimental group and six in the control group. The results were as followings. First, the premarital counselling program influenced the relationships of the premarital couples such as communication, sexual attitude, conflict solution, financial management, openness, interpersonal trust, and intimacy. Second, the male group significantly improved more than the female group in the areas of communication, conflict solution, and sexual attitude. The effects of the program continued to be effective after three months.

• Journal of the Korean Home Economics Association
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• v.43 no.9 s.211
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• pp.15-26
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• 2005

The purpose of this study was to develop an educational program that enhances a single mother's social adaptation (self-esteem and sociality) based on the precedent studies. The subjects of this program were seven single motherswholive in C city in Chung Cheong Namdo. Paired-Sample t-test, individual change and group processing description data, and behavior observation record data were analyzed. Research results are as follows based on the research questions. First, a group of 8 single mothers who participated in the program showed an improvement of their social adaptation. Therefore, the effectiveness of the educational program was verified. Second, as the group session went on, the cohesion among the group members was solidified and their will to participate in the program was increased. Third, generally, individuals' understanding, acceptance, and adaptation toward themselves and others were enhanced. On the whole, the educational program for improving single mother's social adaptation was verified. We need to develop and implement more programs that enhance single mother's social adaptation in the future.

• International Journal of Costume and Fashion
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• v.13 no.1
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• pp.1-10
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• 2013

This study examines existing literature and uses case studies to identify the scope of fashion blogging and the evolving role of the personal style bloggers in the fashion business. Information on six popular personal style bloggers has been gathered to demonstrate the evolving business of these bloggers and their scope of operations that are relevant to fashion. The case of these six bloggers were drawn from popular media publications such as CNN, Wall Street Journal (WSJ), Time, Women's Wear Daily (WWD) and The New York Times. The case study of these six bloggers reveals that these personal style bloggers have used their reach and influence on the blog audience to procure and access business opportunities to grow their enterprise. The findings indicate that affiliation, partnership or collaboration with brands or established designers adds more value to a personal style bloggers resume. However, the findings also indicate that the popular fashion bloggers provide a new opportunity for marketing and promoting fashion brands and products to the younger generation.

• The Korean Journal of Financial Studies
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• v.4 no.1
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• pp.73-92
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• 1998

본 논문은 기독인 경영기업과 일반기업의 자본조달전략에 차이가 존재하는지를 미국 기독인 경영기업의 최고경영자를 대상으로 설문조사를 통해 실증분석하였다. 실증분석에 앞서 성경에 기초하여 부채에 관한 원리를 찾아서 정리하였다. 그 다음 도출된 차입원리에 기초하여 네 개의 가설을 설정하였다. 중심된 가설은 기독인 경영기업과 일반기업의 부채비율에 차이가 존재하는가 이었다. t-검증을 한 결과 두 집단의 부채비율에 통계적으로 유의한 차이는 없었다. 그러나 일부의 기독인 경영기업은 무부채정책을 추구하고 있는 것으로 조사되었다. 본 연구는 기업간의 상이한 자본구조의 차이를 성경적으로 접근하여 설명을 시도하였다는 데 그 의의가 있다.

• Journal of Contemporary Eastern Asia
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• v.12 no.1
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• pp.81-93
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• 2013

Over the past several decades, educational systems in many parts of the world have undergone manifold changes that have significantly affected the work environment of educators. Among other negative impacts of the globalized reforms in higher education has been the increasing prevalence of workplace bullying. The purpose of this research note is to serve different purposes: (1) examine the causes behind the changing landscape of higher education; (2) discuss previous and current research on workplace bullying; (3) introduce the methodology of the Taiwan Higher Education Faculty Survey (THEFS); (4) outline its anticipated outcome.

• Physical Therapy Korea
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• v.14 no.4
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• pp.7-13
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• 2007

The purpose of this study was to investigate correlations among objective measurements of spasticity in patients with brain lesions. Thirty-two stroke and traumatic brain injury subjects participated in the study. Spasticity was quantified using the knee first flexion angle, relaxation index obtained from a pendulum drop test, and the amplitude of a knee tendon reflex test. Pearson's product correlation coefficient was used to examine relationships among these measurements of spasticity. There was a significant positive correlation between the relaxation index and knee first flexion angle in patients with brain lesions (r=.895, p<.01). There was also significant negative correlation between the amplitude of knee tendon reflex and relaxation index (r=-.612, p<.01), and between amplitude and knee first flexion angle (r=-.537, p<.01). Thus, it is possible to use the knee first flexion angle as an objective measure of spasticity, rather than relaxation index, which is more complicated to obtain. Further studies are needed to explore the effects of functional improvement and long-lasting carryover effects of spasticity using a simple objective measure such as the knee first flexion angle from a pendulum test.

• Journal of Contemporary Eastern Asia
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• v.3 no.2
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• pp.1-6
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• 2004

On 27 June 2004, some one million voters went to the polls in Mongolia to elect 76 members of the Great State Hural, Mongolia's parliament. It was the fourth election held in Mongolia under the 1992 constitution. In the previous election, the former communist MPRP won a landslide, ousting the government of former democracy activists. Under the MPRP, Mongolia's economy performed extraordinary well. Surprisingly, the ruling Mongolian People's Revolutionary Party (MPRP) lost its two-thirds majority and half its parliamentarians in the 2004 election. But the Motherland Democracy Coalition (MDC), a coalition of Mongolia's most influential opposition parties, fell short of achieving a majority of its own. After the election, a grand coalition government was formed, paving the way for profound legal, social, and economic reforms.

• Journal of the Korean Chemical Society
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• v.19 no.1
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• pp.21-33
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• 1975

cis-and trans-2-butenedialdioximes are synthesized via 2-butenedials, very unstable precursors, and the conformation of the cis-isomer of those compounds is determined by the NMR spectra of 1,4-dideutero-and 1-deutero-cis-2-butenedialdioximes; it is certain that the conformation has an unsymmetrical structure as shown below.