• 대한의생명과학회지
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• 제18권1호
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• pp.79-82
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• 2012

Acinetobacter infections are of great concern in clinical settings because of multi-drug resistance (MDR) and high mortality of the infected patients. The MDR Acinetobacter baumannii has emerged as a significant infectious agent in hospitals worldwide. The purpose of this study was to determine for molecular characterization of MDR A. baumannii clinical isolates obtained from the Wonju Christian Hospital in Gangwon province of Korea. A total of seventy nonduplicate A. baumannii isolates were collected from the Wonju Christian Hospital in Korea from March to April in 2011. All of the MDR A. baumannii isolates were encoded by $bla_{OXA-23-like}$ gene and all isolates with the $bla_{OXA-23-like}$ gene had the upstream element ISAba1 to promote increased gene expression and subsequent resistance to carbapenem. 16S rRNA methylase gene (armA) was detected in 44 clinical isolates which were resistant to amikacin, and phosphotransferase genes encoding aac(3)-Ia and aac(6')-Ib were the most prevalent. A combination of 16S rRNA methylase and aminoglycoside-modifying enzyme genes (armA, aac(3)-Ia, aac(6')-Ib, and aph(3')-Ia) were found in 31 isolates. The sequencing results for the quinolone resistance-determining region (QRDR) of gyrA and parC revealed the presence of Ser (TCA) 83 Leu (TTA) and Ser (TCG) 80 Leu (TTG) substitutions in the respective enzymes for all MDR. Molecular typing for MDR A. baumannii could be helpful in confirming the identification of a common source or cross-contamination. This is an important step in enabling epidemiological tracing of these strains.

• 보건의료산업학회지
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• 제11권3호
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• pp.105-114
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• 2017

Objectives : The purpose of this study was to investigate the effects of gambling environment factors (being around gambling, gambling ad access) and irrational gambling belief on the gambling behaviors of college students who experienced sports gambling. Methods : Study participants were 240 college students with sports gambling experience. Data were collected through self-report questionnaires and analyzed with SPSS 18.0. Results : Being around gambling and sports gambling ad access have a statistically significant effect on irrational gambling beliefs, which have statistically significant statistical effects on gambling addiction. Self-regulation did not show statistically significant regulatory effects between irrational gambling beliefs and gambling addiction. Conclusions : It is necessary to take a proactive approach to minimize the negative effects of sports betting and to be aware of the rapidly changing sports gambling environment factors.

• Communications for Statistical Applications and Methods
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• 제17권5호
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• pp.725-731
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• 2010

Economic Reliability test plans(ERTP) are proposed considering that the life time of the submitted items follow the Pareto distribution of the second kind. For various specified acceptance number, sample size and producer's risk, a minimum test termination time is obtained. A comparison of proposed plan has been made with the existing plan developed by Aslam et al. (2010). The results are explained by tables and example.

• Journal of Korean Neurosurgical Society
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• 제53권2호
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• pp.108-111
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• 2013

Burr hole drainage has been widely used to treat chronic subdural hematomas (SDH), and most of them are easily treated by simple trephination and drainage. However, various complications, such as, hematoma recurrence, infection, seizure, cerebral edema, tension pneumocephalus and failure of the brain to expand due to cerebro-cranial disproportion may develop after chronic SDH drainage. Among them, intracerebral hemorrhage after evacuation of a recurrent chronic SDH is very rare. Here, we report a fatal case of delayed intracerebral hemorrhage caused by coagulopathy following evacuation of a chronic SDH. Possible pathogenic mechanisms of this unfavorable complication are discussed and a review of pertinent literature is included.

• 대한한의진단학회지
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• 제10권1호
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• pp.141-152
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• 2006

Background and Objectives: The diagnosis of flood stasis pattern is one of the most important methods in oriental medicine. The aim of this study is to Develop clinically useful questionaire of Blood stasis(瘀血) and quantitative analysis. Methods: The questionnaire including symptoms and signs for diagnosis of Blood stasis pattern is studied by delphi method and statistical analysis. Result: By the delphi method and statistical analysis, 14 Items of questionnaries are choosen. Conclusion: Further research is necessary for improvement reliabilities and validities of the questionnaires of Blood stasis pattern.

• Journal of Korean Neurosurgical Society
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• 제53권3호
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• pp.201-203
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• 2013

In most cases, subdural hematoma (SDH) is regarded as a complication of head injury and nontraumatic causes are rare. Moreover, spontaneous chronic SDH in child or adolescent is very unusual. Here, we present the case of a healthy 14-year-old girl who was diagnosed as a spontaneous chronic SDH. The patient presented with severe headache following blurring of vision two weeks ago without any history of trivial head injury. Computed tomography and magnetic resonance imaging depicted a chronic SDH. The cause of the hematoma was not established. After performing burr hole drainage of the hematoma, the patient made an uneventful recovery. We explore the potential risk factors and pathophysiology implicated in this condition. Possible pathogenic mechanisms of this unique case are discussed and a review of the pertinent literature is included.

• Journal of Korean Neurosurgical Society
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• 제58권6호
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• pp.563-565
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• 2015

Juxtafacet cysts are implicated in neural compression. Thus far, it is known that surgical removal is the definitive treatment for symptomatic juxtafacet cyst because spontaneous regression is rare, and the failure rate of conservative treatment is high. We have reported a rare case of right-sided juxtafacet cyst development after the spontaneous resolution of contralateral left-sided facet cyst. The left-sided facet cyst resolved spontaneously without surgical treatment, but a juxtacyst developed on the contralateral facet on the right side, as illustrated on 4-year follow-up magnetic resonance images. To the best of our knowledge, this is the first report of newly developed contralateral juxtafacet cyst after spontaneous regression. Herein, we have discussed the natural history and the management of this rare case.

• 대한두개안면성형외과학회지
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• 제20권6호
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• pp.408-411
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• 2019

Hairless scalp areas can occur due to trauma, tumors, or congenital disease. This aesthetically unpleasing condition can lead to psychosocial distress, and thin skin flaps may be prone to scarring. Treating the hairless scalp by simple excision is challenging because of skin tension. Tissue expanders are a good option for hairless scalp resurfacing. However, a single expansion may be inadequate to cover the entire defect. This report describes good results obtained using a serial resurfacing method involving re-expansion of the flap with a tissue expander to treat two patients with large lesions: one due to aplasia cutis congenital and another who underwent dermatofibrosarcoma protuberance resection. The results suggest that scalp resurfacing by serial tissue expansion using a tissue expander can be used for extensive lesions.

• 대한화학회지
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• 제19권1호
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• pp.21-33
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• 1975

매우 不安定한 中間生成物인 2-butenedial을 거쳐서 cis- 및 trans-2-utenedialdioxime을 合成하고, cis-이성질체의 형태(conformation)를 決定하였다. 1,4-dideutero- 및 1-deutero-cis-2-butenedialdioxime의 NMR 解析에 依해서 目的物의 형태가 아래와 같은 非對稱構造임을 밝혔다.

• Applied Microscopy
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• 제45권3호
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• pp.150-154
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• 2015

Negative staining electron microscopy facilitates the visualization of small bio-materials such as proteins; thus, many electron microscopists have used this conventional method to visualize the morphologies and structures of biological materials. To achieve sufficient contrast of the materials, a number of imaging parameters must be considered. Here, we examined the effects of one of the fundamental imaging parameters, electron beam exposure time, on electron densities generated using transmission electron microscopy. A single site of a negatively stained biological sample was illuminated with the electron beam for different times (1, 2, or 4 seconds) and sets of micrographs were collected. Computational image processing demonstrated that longer exposure times provide better electron densities at the molecular level. This report describes technical procedures for testing parameters that allow enhanced evaluations of the densities of electron microscopy images.