• Title/Summary/Keyword: Chondrosarcoma

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Parachordoma of the Chest Wall -1 case report- (흉벽에 발생한 유척삭종(Parachordoma) -1예 보고-)

  • 박기성
    • Journal of Chest Surgery
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    • v.37 no.10
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    • pp.892-895
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    • 2004
  • Parachordoma is a very rare, slow-growing, and low-grade malignant tumor that occurs in the extremities and trunk. The differential diagnosis includes extraskeletal myxoid chondrosarcoma and chordoma in the histologic finding. Thus, histologic findings with immunohistochemistry may be helpful in distinguishing parachordoma from extraskeletal myxoid chondrosarcoma and chordoma. I report with a brief review of literatures one case of parachordoma of the chest wall which was successfully treated by en-bloc resection and chest wall reconstruction using 2 mm Gore-Tex$^{\circledR}$ soft tissue patch and free from recurrence for 16 months.

Chondrosarcoma of Nasal Septum (비중격에 발생한 연골육종)

  • Rho Young-Soo;Park Il-Seok;Kim Jin;Kim Jin-Hwan;Lim Hyun-Joon
    • Korean Journal of Head & Neck Oncology
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    • v.19 no.1
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    • pp.80-83
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    • 2003
  • Chondrosarcomas are uncommon tumors. Approximately 5-10% are located in the head and neck. Nasal septal chondrosarcoma is exceedingly rare, with an extensive review of the world literature revealing only 50 reported cases. Most occur in middle-aged man. Surgical resection is the definitive treatment of choice. Radiation and chemotherapy are reserved for residual or recurrent diseases and palliation. We present a case of nasal septal chondrosarcoma treated with craniofacial resection and postoperative radiation therapy.

MESENCHYMAL CHONDROSARCOMA ON THE MANDIBULAR BODY: A CASE REPORT (하악골체부에 발생한 간엽성 연골육종: 증례보고)

  • Byun, June-Ho;Choi, Moon-Jeong;Lee, Jong-Sil;Rho, Gyu-Jin;Kim, Jong-Ryoul;Park, Bong-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.34 no.6
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    • pp.653-656
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    • 2008
  • Mesenchymal chondrosarcoma is a rare malignant tumor of bone and soft tissue. This aggressive form of chondrosarcoma represents only 3% to 9% of all chondrosarcomas. This neoplasm is characterized by sheets or clusters of undifferentiated spindle or round cells surrounding discrete nodules of well-differentiated cartilage. We experienced a case of mesenchymal chondrosarcoma on mandibular body. Two years ago, the patient had been treated the intrabony cystic lesion on mandiblular left body. At that time, cartilage portion was not detected in the cystic specimen. Two years after cyst enucleation, the recurred large neoplasm in the mandibular left body was noted, and it was diagnosed as 4.5 cm sized mesenchymal chondrosarcoma. The mandibular tumor was widely resected and rigid-plate and cervical musculocutaneous flap were used for reconstruction of resected bone and soft tissues. No complications and recurrence were noted for 6 months postoperatively.

Mesenchymal Chondrosarcoma of the Calcaneous (종골에 발생한 간엽성 연골육종 - 1예 보고 -)

  • Sung, Ki-Sun;Son, Jeong-Gyeong;Cho, Eun-Yoon
    • The Journal of the Korean bone and joint tumor society
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    • v.11 no.2
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    • pp.219-223
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    • 2005
  • Mesenchymal chondrosarcoma is very rare and mostly occurs in lower extremity, especially femur, head and face, and pelvis in order. An eleven-year old male patient suffered from left heel pain for several months and underwent biopsy at another hospital. A Malignant bone tumor was suspected, so the patient was transferred to our hospital. We reviewed the outside pathologic slide, which revealed the diagnosis of mesenchymal chondrosarcoma. It was treated by a below knee amputation. Three months later, a chest computed tomography (CT) revealed multiple metastatic nodules in both lungs. All metastatic nodules were surgically excised and the patient received postoperative chemotherapy. As far as our knowledge, mesenchymal chondrosarcoma in the calcaneus is the first case in the world. Thus, we report a case of mesenchymal chondrosarcoma in the calcaneus with thorough review of documents.

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Multicentric Chondrosarcoma - case report - (다발성 연골육종 1례 보고)

  • Jeon, Dae-Geun;Lee, Jong-Seok;Kim, Sug-Jun;Lee, Soo-Yong
    • The Journal of the Korean bone and joint tumor society
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    • v.3 no.2
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    • pp.112-118
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    • 1997
  • Multicentric chondrosarcoma other than the mesenchymal subtype is rare separate entity. We experienced a case with nonmonomelic synchronous multicentric chondrosarcoma without any preexisting lesions of Oilier's disease or Maffucci's syndrome. To our knowledge, there was no report of synchronous nonmonomelic multicentric chondrosarcoma. A thirty-three year old man had right distal thigh pain of one and half year. Bone scan showed hot lesions on medial condyle of right femur and shaft of left femur. Plain X-ray showed osteolytic lesion on right femur and slight cortical thickening and calcific lesion was observed on left femoral shaft. Curettage and bone cement filling was done on both lesions. The pathology reports were grade I chondrosarcoma on both side of femur. At one month from operation, pathologic fracture of left femur occurred on bone cement-host bone junction. Conservative treatment and radiotherapy of 60Gy was done. At 8 months from operation, nonunion was evident. Segmental resection of left femur with contralateral fibula graft and second look operation on right condyle lesion were done. At 6 months from revision, fracture occurred at host-graft bone junction. We removed previous hardware and applied long DCP and massive autogenous bone graft. Afterwards, the patient looks good and union was progressing. But at 4 years from last operation, hypertrophic nonunion occurred. Another revision was done with condylar plate and bone graft and now he is well without any sign of local recurrence or metastasis.

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Intracranial Extraskeletal Myxoid Chondrosarcoma : Case Report and Literature Review

  • Park, Jin Hoon;Kim, Mi-Jung;Kim, Chang Jin;Kim, Jeong Hoon
    • Journal of Korean Neurosurgical Society
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    • v.52 no.3
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    • pp.246-249
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    • 2012
  • Intracranial extraskeletal myxoid chondrosarcoma is extremely rare, with only seven patients previously reported. We present a case report of a 21-year-old woman admitted for weakness in her right extremities and symptoms of increased intracranial pressure. Magnetic resonance imaging (MRI) revealed hydrocephalus and a well-enhanced large mass around her left thalamus. A left parietal craniotomy and a cortisectomy at the superior parietal lobule were performed. Total surgical resection was also performed, and pathology results confirmed an extraskeletal myxoid chondrosarcoma. Postoperative MRI showed no residual tumor, and the patient underwent radiotherapy. After six months of radiotherapy, the patient's headache and weakness had improved to grade IV. This malignant tumor showed high rates of recurrence in previous reports. We here report another occurrence of this highly malignant and rare tumor in a patient treated using total surgical excision and adjuvant radiotherapy.

A case of canine chondrosarcoma from the rib (늑골에서 발생한 개연골육종의 증례)

  • Kim, Sung-Jae;Kwak, Ho-Hyun;Park, In-Chul;Yoon, Byung-Il;Han, Jeong-Hee
    • Korean Journal of Veterinary Service
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    • v.35 no.2
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    • pp.147-151
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    • 2012
  • We report large tumors of the left thoracic cavity, which arose from the ribs, were diagnosed as chondrosarcoma in a 4-year-old male mixed dog. The dog was presented with swelling in the left side of the chest wall and lameness. The masses were found to be circumscribed, whitish-grey, large and firm. The cut surface revealed whitish-grey lobules of varying size with cartilaginous consistency. Those were subsequently metastasized to the lung and mandibular lymph node. Histologically, the tumors were made up of clusters of chondroid cells having pleomorphic hyperchromatic nuclei with occasional mitosis. A special and immunohistochemical staining was performed to confirm the diagnosis. Chondroid matrix in tumor showed a positive reaction for alcian blue-periodic acid-Schiff staining. Immunoreactivity to S-100 proteins was present in the cytoplasm and/or nucleus of chondrocytes in tumor. The final diagnosis was grade III chondrosarcoma in the rib, considering histological features in grading criteria.

Computed Tomography and Magnetic Resonance Imaging Features of Spinal Chondrosarcoma in a Cat

  • Minhee Lee;Sang-Kwon Lee;Juyoung Shin;Seulgi Bae;Kija Lee
    • Journal of Veterinary Clinics
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    • v.41 no.2
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    • pp.133-138
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    • 2024
  • An 8-year-old, spayed female Persian cat weighing 3.6 kg presented with a lumbosacral mass and bilateral weight bearing hindlimb lameness. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a dumbbell-shaped heterogeneous mass extending through the internal surface of the ileum and surrounding the lumbosacral junction. CT also revealed extensive osteoproliferation and bone lysis of the sacrum, but no evidence of any pulmonary metastasis. Furthermore, MRI revealed a focal area in the spinal cord showing connection with the adjacent tumor, suggesting tumor invasion into the spinal cord. Low-grade myxoid chondrosarcoma was histopathologically diagnosed. This is the first report describing CT and MRI findings of spinal cord chondrosarcoma in veterinary medicine. This study suggests that combining CT with MRI is a more sensitive tool for evaluating spinal tumors than using CT or MRI alone.

Synchronous Monomelic Juxta-articular Multicentric Chondrosarcoma -A Case Report- (동시성 단지성 관절 근접 다발성 연골 육종 -증례 보고-)

  • Oh, Joo-Han;Kim, Jae-Yoon;Gong, Hyun-Sik;Kim, Woo-Sung;Kim, Tae-Yune
    • The Journal of the Korean bone and joint tumor society
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    • v.12 no.1
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    • pp.71-77
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    • 2006
  • Chondrosarcoma is one of the most common types of primary bone sarcoma. With the exception of the mesenchymal subtype, chondrosarcomas are usually low-grade lesions and rarely show multicentricity or distant metastasis. Only rare cases of multicentric chondrosarcomas have been reported in association with Ollier's disease and Maffucci's syndrome. To our knowledge, no report has been issued of a synchronous multicentric chondrosarcoma occurrence across a joint. We experienced a 30-year-old man with a synchronous monomelic juxta-articular multicentric chondrosarcoma across a shoulder joint in the absence of pulmonary and visceral metastases. He was treated by curettage and cement filling with allograft in the acromion and wedge resection with cement filling in the proximal humerus. At the 18-month follow-up, there was no evidence of recurrence, and the patient had full range of motion without pain.

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