• 한국동물위생학회지
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• 제46권4호
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• pp.357-362
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• 2023

A 7-year-old male Yorkshire Terrier dog was present to an animal clinic and a large soft mass was found in the spleen by radiological examination, and total splenorectomy was performed. Grossly, a large protruded splenic mass was soft to moderately firm and multilobulated. On the cut surface, the mass was off-white to tan, dark red, and rust colored with many cavitation and had gelatinous areas. Histologically, the tumor cells were characterized by coexistence of the primitive mesenchymal tissues and mature or immature cartilage tissues. Primitive mesenchymal areas were composed of round/oval or spindle shaped immature cells with high mitosis. The tumor cells of the cartilage areas were located in basophilic cartilaginous matrix. Intercellular matrix in the cartilaginous areas was stained blue with Masson's trichrome and deep blue with alcian blue, respectively. Immunohistochemically, the cartilaginous tumor cells demonstrated positive reactions for vimentin and S-100, and surrounding mesenchymal tumor cells are immunopositive for vimentin. This case was diagnosed as splenic extraskeletal mesenchymal chondrosarcoma of a Yorkshire Terrier dog, a toy breed.

• Journal of Yeungnam Medical Science
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• 제17권1호
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• pp.87-92
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• 2000

저자들은 영남대학교 의과대학 부속병원에서 간엽성 연골육종으로 진단받은 3례를 대상으로 임상 병리학적 특징을 분석하여 다음과 같은 결과를 얻었다. 환장의 연령은 25세에서 32세였고 평균연령은 28세였다. 종양의 평균 크기는 7.3cm였다. 조직학적으로 종괴는 이형성의 소세포로 구성된 고밀도의 부분과 분화가 좋은 초자양의 연골 조직이 섞여 있었다. 3례에서 종양 세포들은 S-100단백과 NSE에 양성이었고 desmin에 모두 음성이었다.

• 대한기관식도과학회지
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• 제4권2호
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• pp.249-253
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• 1998

Chondrosarcoma of bone commonly involve the pelvis, femur and shoulder girdle but the hyoid bone is a rare site for primary chondrosarcoma with approximately 10 cases having been reported in the literature. Radiologically it was well marginated and radiolucent mass with medullary bone destruction and central calcification. Wide surgical excision with or without radiotherapy is genera31y regarded as the treatment of choice for chondrosarcoma. Histopathology of chondrosarcoma was classified to clear cell chondrosarcoma, mucinous chondrosarcoma, dedifferentiated chondrosarcoma, and mesenchymal chondrosarcoma. We report a case of chondrosarcoma that originated from the right greater cornu of the hyoid bone, which underwent excision of the tumor with hemihyoidectomy and postoperative radiotherapy was performed.

• Imaging Science in Dentistry
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• 제42권2호
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• pp.115-119
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• 2012

Today, ultrasound imaging is being widely used to assess soft tissue lesions in the maxillofacial region. However, ultrasound investigations of intra-osseous lesions are rare, especially for tumors of the jaws. This report emphasized the capability of this useful imaging modality in identification of the characteristics of malignant conditions involving the bone. Mesenchymal chondrosarcoama, one of the unusual malignant conditions of the jaw, was presented in a young male with significant facial swelling. Different imaging modalities parallel with the histopathologic investigation confirmed the diagnosis. Interestingly, destruction of the bony cortex and new bone formation with a characteristic "sun ray appearance", highly suggestive of sarcomas, was manifested on the ultrasonograph. Thus, this report presented the ultrasonographic features of chondrosarcoma of mandible and considered the ultrasonography to be a useful imaging modality to evaluate intra-osseous jaw lesions.

• 대한두경부종양학회:학술대회논문집
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• 대한두경부종양학회 1986년도 제3차 학술대회 연제순서 및 초록집
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• pp.6.2-8
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• 1986

• 대한세포병리학회:학술대회논문집
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• 대한세포병리학회 1992년도 제5차 추계학술대회 초록집
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• pp.17-17
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• 1992

• 대한골관절종양학회지
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• 제3권2호
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• pp.112-118
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• 1997

Multicentric chondrosarcoma other than the mesenchymal subtype is rare separate entity. We experienced a case with nonmonomelic synchronous multicentric chondrosarcoma without any preexisting lesions of Oilier's disease or Maffucci's syndrome. To our knowledge, there was no report of synchronous nonmonomelic multicentric chondrosarcoma. A thirty-three year old man had right distal thigh pain of one and half year. Bone scan showed hot lesions on medial condyle of right femur and shaft of left femur. Plain X-ray showed osteolytic lesion on right femur and slight cortical thickening and calcific lesion was observed on left femoral shaft. Curettage and bone cement filling was done on both lesions. The pathology reports were grade I chondrosarcoma on both side of femur. At one month from operation, pathologic fracture of left femur occurred on bone cement-host bone junction. Conservative treatment and radiotherapy of 60Gy was done. At 8 months from operation, nonunion was evident. Segmental resection of left femur with contralateral fibula graft and second look operation on right condyle lesion were done. At 6 months from revision, fracture occurred at host-graft bone junction. We removed previous hardware and applied long DCP and massive autogenous bone graft. Afterwards, the patient looks good and union was progressing. But at 4 years from last operation, hypertrophic nonunion occurred. Another revision was done with condylar plate and bone graft and now he is well without any sign of local recurrence or metastasis.

• 대한골관절종양학회지
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• 제12권1호
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• pp.71-77
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• 2006

연골 육종은 가장 흔한 원발성 골육종 중 하나로, 간엽성 연골육종을 제외하면 대체로 저 악성도 병변이며, 다발성 발현이나 원격 전이가 드문 것으로 알려져 있다. 다발성 내연골종(Ollier's disease)과 Maffucci's 증후군에서 다발성 연골육종이 발생한 례가 드물게 보고되었으며, 아직까지 한 관절을 사이에 두고 그 근위부와 원위부에서 연골육종이 동시에 발생한 례는 보고된 적이 없었다. 저자들은 30세 남자 환자에서 폐나 내장의 전이를 동반하지 않고, 한쪽 견관절을 사이에 두고 견갑골의 견봉과 상완골에서 동시에 발생한 다발성 연골육종을 경험하였으며, 이를 "동시성 다발성 관절 근접 연골육종"이라 명하였다. 견봉에 위치한 병변은 소파술과 함께 동종 골이식과 시멘트 충전술을 시행하였으며, 근위 상완골 병변은 설상 절제술과 시멘트 충전술을 시행하였다. 수술 후 18개월까지 재발의 증거가 관찰되지 않았으며, 통증 없이 전 범위 운동이 가능하였다.

• 동의생리병리학회지
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• 제27권1호
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• pp.136-138
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• 2013

Carcinosarcoma of gallbladder is a rare malignant tumor characterized by malignant epithelial and malignant mesenchymal components. Its pathogenesis is unknown and most of carcinosarcomas of gallbladder are associated with poor survival because the disease presents at an advanced stage. A 69-year-old man presented with right upper quadrant pain. The preoperative diagnosis was gallbladder cancer, and thus, curative radical cholecystectomy was performed. Pathologic examination of the surgical specimen revealed that the tumor was composed of carcinomatous components with adenocarcinoma and squamous cell carcinoma, and sarcomatous components with spindle cell sarcoma and chondrosarcoma, which was consistent with a diagnosis of primary carcinosarcoma of the gallbladder. The tumor was found to extend to the pericholecystic fat and no metastasis in regional lymph nodes.

• Journal of Korean Neurosurgical Society
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• 제58권3호
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• pp.281-285
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• 2015

Myxomas are rare benign tumors that originate from mesenchymal tissue. They usually develop in the atrium of the heart, the skin, subcutaneous tissue, or bone. Involvement of the skull base with an intracranial extension is very rare and not well-described in the literature. We report a rare case of primary intracranial ossifying myxoma arising from the anterior skull base and mimicking a huge chondrosarcoma, and we review the relevant literature.