• Journal of Life Science
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• v.8 no.1
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• pp.72-84
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• 1998

Sprague Dawley rats(24 weeks of age) were divided and were given normal diet for 6 weeks, followed by normal diet and 2% cholesterol diet for 14 weeks. During these periods, 10 weeks’ exercises are performed after 4 weeks. And then we analyze the blood and adipose tissue by decapitating those rats. 1. Serum total cholesterol was enhenced by cholesterol diet, while aerobic exercise tended to reduce it. 2. Cholesterol diet slightly reduced serum HDL-C and LDL-c, where as aerobic exercise showed a tendency to decrease it. 3. Cholesterol diet slightly reduced phospholipid and triglyceride, but aerobic exercise showed a tendency to increase them. 4. Aerobic exercise significantly decreased adipose tissue in normal diet rats and tended to reduce it in cholesterol-dietary rats. These results suggest that aerobic exercise decrease serum total cholesterol and LDL-C, and as a result can prevent atherosclerosis.