• Title/Summary/Keyword: Choice-based Sample

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Evaluation of DNA Extraction Methods from Low Copy Number (LCN) DNA Samples for Forensic DNA Typing

  • Eom, Yong-Bin
    • Biomedical Science Letters
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    • v.15 no.3
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    • pp.229-232
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    • 2009
  • DNA isolation for PCR-based short tandem repeat (STR) analysis is essential to recover high yields of amplifiable DNA from low copy number (LCN) DNA samples. There are different methods developed for DNA extraction from the small bloodstain and gloves, commonly found at crime scenes. In order to obtain STR profiles from LCN DNA samples, DNA extraction protocols, namely the automated $iPrep^{TM}$ $ChargeSwitch^{(R)}$ method, the automated $QIAcube^{TM}$ method, the automated $Maxwell^{(R)}$ 16 DNA $IQ^{TM}$ Resin method, and the manual $QIAamp^{(R)}$ DNA Micro Kit method, were evaluated. Extracted DNA was quantified by the $Quantifiler^{TM}$ Human DNA Quantification Kit and DNA profiled by $AmpFISTR^{(R)}$ $Identifiler^{(R)}$ Kit. Results were compared based on the amount of DNA obtained and the completeness of the STR profiles produced. The automated $iPrep^{TM}$ $ChargeSwitch^{(R)}$ and $QIAcube^{TM}$ methoas produced reproducible DNA of sufficient quantity and quality trom the dried blood spot. This two automated methods showed a quantity and quality comparable to those of the forensic manual standard protocols normally used in our laboratory. In our hands, the automated DNA extraction method is another obvious choice when the forensic case sample available is bloodstain. The findings of this study indicate that the manual simple modified $QIAamp^{(R)}$ DNA Micro Kit method is best method to recover high yields of amplifiable DNA from the numerous potential sources of LCN DNA samples.

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Model of Simultaneous Travel time and Activity Duration for worker with Transportation Panel Data

  • Kim Soon-Gwan
    • Proceedings of the KOR-KST Conference
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    • 1998.09a
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    • pp.160-167
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    • 1998
  • Recent world-wide interest in activity-based travel behavior modeling has generated an entirely new perspective on how the profession views the travel demand process. This paper seeks to further promote the case of activity-based travel behavior models by providing some empirical evidence of relationship between travel time and activity duration decision for worker with transportation panel data. The travel time from home to work and from work to home, without activity involvement, is estimated by the Ordinary Least Squares (OLS) method. And, the travel time to and from the selected activity and the activity duration are modeled simultaneously by the Three Stage Least Squares (3SLS) method due to the endogenous relationship between travel time and activity duration. Two kinds of models, OLS and 3SLS, include selectivity bias corrections in a discrete/continuous framework, because of the inter-relationship between the choice of activity type/travel mode (discrete) and the travel time/activity duration (continuous). Estimation is undertaken using a sample of over 1300 household two-day trip diaries collected from the same travelers in the Seattle area in 1989. The behavioral consequences of these models provide interesting and provocative findings that should be of value to transportation policy formulation and analysis.

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A Study on the Artillery shell's EFD based on Charge (장약에 기반한 포병탄 EFD 산출 모형에 관한 연구)

  • Kim, Hyunsik;Ma, Jungmok
    • Journal of the Korea Society for Simulation
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    • v.28 no.1
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    • pp.11-21
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    • 2019
  • Modeling and simulation(M&S) method are used to quantify the weapon effectiveness. The weapon effectiveness of artillery shells was also partially studied, but there was a lack of research on the effects of the choice of charge. Therefore, this paper presents an artillery shell's EFD(Expected Fractional Damage) calculation model based on the charge and identifies differences in the weapon effectiveness of 3D building targets according to the selection of the charge. First, the input data of the calculation model was collected and a required number of shoots was calculated to achieve the desired effects using the proposed model. Finally, a paired sample t-test was conducted to verify the proposed model.

State-of-the-art update for diagnosing diabetic foot osteomyelitis: a narrative review

  • Inha Woo;Seung Jae Cho;Chul Hyun Park
    • Journal of Yeungnam Medical Science
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    • v.40 no.4
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    • pp.321-327
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    • 2023
  • Recently, the International Working Group on the Diabetic Foot and the Infectious Diseases Society of America divided diabetic foot disease into diabetic foot infection (DFI) and diabetic foot osteomyelitis (DFO). DFI is usually diagnosed clinically, while numerous methods exist to diagnose DFO. In this narrative review, the authors aim to summarize the updated data on the diagnosis of DFO. An extensive literature search using "diabetic foot [MeSH]" and "osteomyelitis [MeSH]" or "diagnosis" was performed using PubMed and Google Scholar in July 2023. The possibility of DFO is based on inflammatory clinical signs, including the probe-to-bone (PTB) test. Elevated inflammatory biochemical markers, especially erythrocyte sedimentation rate, are beneficial. Distinguishing abnormal findings of plain radiographs is also a first-line approach. Moreover, sophisticated modalities, including magnetic resonance imaging and nuclear medicine imaging, are helpful if doubt remains after a first-line diagnosis. Transcutaneous bone biopsy, which does not pass through the wound, is necessary to avoid contaminating the sample. This review focuses on the current diagnostic techniques for DFOs with an emphasis on the updates. To obtain the correct therapeutic results, selecting a proper option is necessary. Based on these numerous diagnosis modalities and indications, the proper choice of diagnostic tool can have favorable treatment outcomes.

Social Benefits of Improved Water Quality at the Taehwa River Based on Citizen's Willingness-to-Pay (시민지불의사에 기초한 태화강 수질개선의 사회적 편익)

  • Kim, Jae-Hong
    • Journal of Environmental Policy
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    • v.6 no.1
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    • pp.83-109
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    • 2007
  • This study evaluates citizen's willingness-to-pay for the benefits from improved water quality of the Taehwa river in Ulsan, Korea, using a contingent valuation method with double-bounded dichotomous choice. The estimation results of the bivariate probit model shows the amounts of willingness-to-pay are monthly 3,458.5 Korean Won per household and yearly 14,760 million Korean Won for total households in Ulsan, Korea. These estimates are equivalent to the social values of improved water quality of the Taehwa river. This study also tests the inter-dependence between two answers, which may occur in the responses of the questions for the double-bounded dichotomous choice, and all the null hypotheses on the inter-dependence are rejected in this study.

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Economic Valuation of Urban Riverine Restoration and A Test of Social Desirability Bias (도심하천복원 경제가치 추정에서 사회규범편의 검정)

  • Choi, Andy S.;Sung, Chan Yong;Baek, Hyojin
    • Environmental and Resource Economics Review
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    • v.28 no.4
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    • pp.645-673
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    • 2019
  • The hypothetical nature of stated preferences can lead to a hypothetical bias that might work as a normative pressure, influencing survey responses. This paper aims to test the impact of social desirability bias by comparing economic estimates based on both subjective and objective valuation questions. The case study is about an urban riverine restoration project in Deajeon, South Korea. As valuation methods both contingent valuation and choice experiments were comparatively applied. Based on a nationally representative sample of 1,000 respondents, the test results offered contrasting conclusions between two test approaches. Accroding to the estimation results based on the conventional valuation, the marginal willingness to pay estimates are 10,500 KRW from CV; and 18,600 KRW for improving water quality, 2,200 KRW for the inside view, 8,900 KRW for the outside view, and 5,800 KRW for biodiversity from CE. A segmentation-based approach is a conventionally used method, which showed a limited impact of social desirability on willingness to pay estimates. The alternative parameterization-based approach measures a model-wide impact of social desirability, proving a significant bias. Although the study positioned a cheap-talk statement before the valuation section of the survey questionnaires, which might have pre-screened the bias, the overall implications of the results suggest a caution in reducing and observing hypothetical bias. There might remain a significant and substantial hypothetical bias even after cheap-talk, particularly in situations with strong social desirability, so that the potential role of objective valuation questions is guaranteed.

An Empirical Study of Logistics Performance and Outsourcing Types of Korean Distributors (유통업체의 정보물류시스템 아웃소싱 유형과 물류성과에 관한 실증연구)

  • Yoo, Chang-Kwon
    • Journal of Distribution Science
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    • v.12 no.4
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    • pp.41-46
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    • 2014
  • Purpose - This study focused on providing strategic findings that make significant sense for companies that are looking for a future outsourcing strategy. The study analyzes the results of outsourcing in the information logistics systems field and verifies the results through experimental study of the performance delivered by logistics outsourcing types. Research design, data, and methodology - The study sample was assembled based on a random sampling method used to extract the initial 451 companies from a list of Korean distributors, wholesalers, and retailers. Following that sample process, 423 companies were confirmed by verifying their e-mail address and contacts (telephone and fax numbers), and were selected as initial research subjects. We reduced that number to 331 companies for the survey sample through telephone interviews in advance with the 423 companies that were targeted, in order to verify whether they are in the field of outsourcing of information logistics systems. The period of the survey extended from November 10, 2013 to January 10, 2014. The number of collected surveys totaled 181. We reviewed the contents of the survey responses, and reduced the number of research subjects to 175. In this study, we used a standard analysis to investigate whether there is a difference in distribution results based on different types of outsourcing information in the logistics system field and, through T-verification, we investigated whether the difference between distribution results in each group resulting from that standard analysis is statistically significant. Results - These results show that there is a difference in distribution outcome, based upon type of distribution outsourcing. In addition, we determined that they are meaningful results by confirming that, for usability and to improve the capabilities of a third-party logistics service supplier, both the choice of reasonable outsourcing types and the enhancement of various types of alliances are very important success factors. Taken together these study results, with a goal of enhancing the distribution capabilities of a Korean distributor, can be implemented to enhance management results achievable by supplying an information logistics system in the form of strategic outsourcing rather than in the form of simple outsourcing. In addition, the outcomes of logistics distributors in Korea that are using outsourcing in the logistics information systems field show high performance results in commercial endeavors in the following order: competitive, pre-competitive, non-competitive, and pro-competitive. Conclusions - This study focused on providing strategic findings. However, in the case of outsourcing in the field of information logistics systems of Korean distributors, there has been a focus on simple outsourcing rather than on strategic outsourcing; furthermore, there has been a concentration on non-competitive forms instead of pro-competitive forms, which could achieve better distribution results. This discussion is presented in more detail in the analysis results of this study.

The Relationships between Age, Socio-ecoomic Status and Clothing Behavior of Korean Men (성인 남자의 연령 및 사회.경제적 지위와 의복행동과의 상관 연구)

  • 고애란
    • Journal of the Korean Home Economics Association
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    • v.25 no.1
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    • pp.1-10
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    • 1987
  • The purpose of this study was to investigate the relationships between demographic variables and seven aspects of clothing behavior of adult males, and to attempt to develop the measurement of men's clothing behavior. Age was ranked by five gradation (20∼60 ages) and socio-economic status was divided into three categories (high, middle, low) based on the subjects' education, occupation and economic status. Six aspects of clothing comfort, satisfaction, status symbol, conformity, fashion interest and clothing acceptance I were assessed with Koh's, Chung's and Lee's questionnaires. Clothing acceptance by line-drawing of clothing syles representing different levels of formality for occasions designed to measure the awareness of appropriate clothing category of business suits. The questionnaires in this study were administered to a sample of men living in Seoul. The sample was drawn by the random-cluster sampling method. The data from 362 respondants were analysed. To determine the internal validity of clothing behavior mesurement, factor analysis was computed, whereas to determine the reliability, Cronbach's alpha was calculated. The statistical methods adopted were correlation, one-way ANOVA, and multiple regression. The results obtained in this study were as follows: 1) As for clothing behavior instruments, items dealing with status symbol and fashion nterest were proved to be satisfactory as a measurement of adult males. Eight factors emerged on clothing acceptance Ⅱ, most of which were representing unappropriate clothing choice for occasion. 2) Demographic variables were significantly related to the adult males' clothing behavior. (1) Age was positively related to clothing conformity but negatively to fashion interest. (2) Socio-economic status was positively related to clothing satisfaction, status symbol, and fashion interest but negatively to clothing confort. (3) When age was controlled, socio-economic status was negatively related to comfort in 40∼50s age group only, and negatively related to clothing conformity in 20∼30s age group only. (4) Four subscales of clothing acceptance Ⅱ representing unappro-priate clothing practice for selected occasions were negatively related to age and/or socio-economic status.

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A study the effect of sex on choice of occupation and work location and on earnings : Comparison of on-site workers with home-based workers in the U.S. (성별(性別)이 직업과 시장노동 장소의 선택 및 소득에 미치는 영향에 관한 연구 : 미국의 직장근무자와 재택근무자의 비교를 중심으로)

  • 김효정
    • Journal of the Korean Home Economics Association
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    • v.36 no.7
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    • pp.123-141
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    • 1998
  • 본 연구는 미국의 직장근무자와 재택근무자의 비교를 통해, 남성과 여성의 소득차이를 살펴보고 이를 설명하는 요소들에 대해 분석하였다. 본 연구를 위해 설정된 가설은 다음과 같다.: (1) 성별은 직업과 시장노동의 장소를 선택하는데 있어서 유의한 요소이다. (2) 직업 및 시장노동의 장소가 결정된 후에도 성별은 시간당 소득에 영향을 미치는 변수이다. 연구자료로는 Census of Population and Housing, 1990 [United States]: Public Use Microdata Sample: 1/10,000 Sample이 이용되었으며, 16세 이상, 65세 이하의 응답자로 일주일에 적어도 한 시간 이상 일하는 근로자를 중심으로 하여 7,272명이 연구 대상으로 고려되었다. 직업 및 시장노동의 장소에 대한 선택에서 성별의 영향을 살펴보기 위해 판별분석이 행해졌으며, 분석 결과 교육수준, 연령, 인종, 남녀의 수, 주택구조와 함께 성별이 유의한 요소임이 밝혀졌다. 직업과 시장노동의 장소가 결정된 후 성별이 시간당 소득에 미치는 영향을 알아보기 위해 전체표본과 6개의 직업범주에 따라 회귀분석이 실시되었다. 전체표본을 대상으로 한 회귀분석의 결과, 시간당 소득을 예측하는데 있어서 성별은 유의하지 않은 것으로 나타났으나, 6개의 직업범주에 따라 시간당 소득을 추정한 결과, 성별은 모든 직업범주에서 유의한 것으로 나타났다. 그러나 재택근무자가 되는 것은 시간당 소득을 규정하는데 있어서 유의한 변수가 아닌 것으로 나타났다. 이것은 특정 직업 내에서 시장노동의 장소보다는 성별이 재택근무자에 있어서 소득의 차이를 설명하는데 중요한 요소임을 암시하고 있다. 본 연구에서 사용된 자료는 직업 및 시장노동의 장소에 대한 결정이나 소득에 영향을 미칠 수 있는 변수들에 대한 충분한 정보를 갖고 있지 않고, 또한 재택근무자의 표본수가 너무 적었기 때문에 일부 변수들은 직업의 선택이나 소득을 예측하기 위한 요소들로 포함될 수 없었다. 따라서 후속연구에서는 이를 보완해야 할 것이며, 최근 들어 우리 나라에서도 재택근무에 대한 관심이 대두되고 있으나 아직 개념정의나 그 중요성과 가치, 그리고 실태 파악과 같은 연구가 활발히 이루어지지 못하고 있으므로 이에 대한 심층적인 연구가 행해져야 할 것이다.

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A Study of The Purchasing Tendency of Health-care Masks Based on The User-centered Design Concept-centered on the Form and Color of the Mask (사용자 중심 디자인개념에 기초한 보건용 마스크의 구매 경향성에 관한 연구 - 마스크의 형태와 색상 중심으로)

  • Ma, Lin;Kim, Myung-Soo
    • Journal of the Korea Convergence Society
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    • v.11 no.9
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    • pp.143-154
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    • 2020
  • Due to the widespread of COVID-19 pandemics, as the health care supplies. Thus the facial mask has been transformed from personal health product into social epidemic prevention product, and its design is more inclined to be User-centered design. First employed health facial mask which is sold in the market as the method subject, under the concept of " User-centered design", this article analyzes the design elements such as appearance and color of the facial mask. Second used the analysis approach of sample, character and positioning map, this article conducts the comparative analysis research of collected sample and data and find the relationship of User-centered design, purchase tendency and health care facial mask. When the users purchase the mask, through the research on the relationship between the choice of form or color of mask and design element of mask, it can compensate for the blank spot of design and has some references.